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The map label for this gene is mraY [H]

Identifier: 119897172

GI number: 119897172

Start: 942301

End: 943389

Strand: Direct

Name: mraY [H]

Synonym: azo0881

Alternate gene names: 119897172

Gene position: 942301-943389 (Clockwise)

Preceding gene: 119897171

Following gene: 119897173

Centisome position: 21.53

GC content: 66.57

Gene sequence:

>1089_bases
ATGCTGCTCGAACTCGCCCTCTGGCTCGGCCAGGACATCCGCGGTTTCAACGTCTTCGGCTACATCACGCTGCGGACGGT
GCTGGCCGCGCTCACCGCGCTGGCGATCTCGCTCACCGCCGGGCCGGGCGTCATCCGCTGGCTGGCCGCCAAGAAAATCG
GCCAGGCGGTGCGCGACGACGGCCCCAAGTCGCACCTCACCAAGGCCGGTACGCCGACCATGGGCGGCGCGCTGATCCTG
ATCGCCATCGGCATCACCATCCTGCTGTGGGGCGATCTGCGCAACGCCTACGTGTGGGTCACGCTGCTGGTCACGCTCGG
CTTCGGCGCGGTGGGCTGGGTGGATGACTGGCGCAAGGTGGTGCACCGCGACCCGAAGGGCCTCGCGAGCCGCTGGAAGT
ATTTCTGGACCTCGGCGATCGCGCTCGGCGCTTCGATCTTCCTCGGTCTCAGCGCCACCACGCCGGCCGAAACCGAACTG
ATCGTGCCCTTCTTCAAGGCGGTGGCCTATCCGCTCGGCGTCTACGGCTTCATCGCGCTCACCTACTTCGTCATCAACGG
CACCAGCCACGCGGTCAACCTCACCGACGGCCTGGACGGCCTGGCGATCATGCCGACGGTGATGGTCGCCGGCGCACTGG
CGATCTTCGCCTACGTCGCCGGCCACGCCGGCTTCTCCAAGTACCTCGGCGTGCCCTACATCGCCGGCGCGGGCGAGCTC
GCGGTGTTCTGCGGCGCGATCTGCGGTGCCGGTCTCGGCTTCCTGTGGTTCAACGCCTATCCGGCCGAAGTCTTCATGGG
CGACGTCGGCGCGCTCGCGCTCGGCGCCGCGCTTGGCACCATCGCGGTCGTGGTGCGGCAGGAAATCGTGCTCTTCATCA
TGGGCGGCCTGTTCGTCGCCGAAACCCTCTCGGTGATGGTGCAGGTGCTGTACTTCAAGGCATCCGGGGGCAAGCGCATC
TTCCGCATGGCGCCGCTGCATCACCACTACGAACTGAGCGGCTGGAAGGAAACCCAGGTGGTGGTGCGCTTCTGGATCAT
CACCCTGATGCTGGTGTTGTTCGGCCTGTCGACGCTGAAACTGAGATGA

Upstream 100 bases:

>100_bases
GTGCTGGTGAAGGGCTCGCGCTTCATGAAGATGGAGCGGGTGGCGGACGCGCTTGCGGCACTGCACAATGGCGCCCCCCA
AAAGGACACGAACTCGTAAC

Downstream 100 bases:

>100_bases
CGCAGCCGTCCTTCTCCTCCTCGCTTGCTGGCCGCCACGTGCTCGTGCTCGGGCTGGGCGAGTCCGGTCTGGCCATCGCC
CGCTGGTGCGCGCGCTGCGG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MLLELALWLGQDIRGFNVFGYITLRTVLAALTALAISLTAGPGVIRWLAAKKIGQAVRDDGPKSHLTKAGTPTMGGALIL
IAIGITILLWGDLRNAYVWVTLLVTLGFGAVGWVDDWRKVVHRDPKGLASRWKYFWTSAIALGASIFLGLSATTPAETEL
IVPFFKAVAYPLGVYGFIALTYFVINGTSHAVNLTDGLDGLAIMPTVMVAGALAIFAYVAGHAGFSKYLGVPYIAGAGEL
AVFCGAICGAGLGFLWFNAYPAEVFMGDVGALALGAALGTIAVVVRQEIVLFIMGGLFVAETLSVMVQVLYFKASGGKRI
FRMAPLHHHYELSGWKETQVVVRFWIITLMLVLFGLSTLKLR

Sequences:

>Translated_362_residues
MLLELALWLGQDIRGFNVFGYITLRTVLAALTALAISLTAGPGVIRWLAAKKIGQAVRDDGPKSHLTKAGTPTMGGALIL
IAIGITILLWGDLRNAYVWVTLLVTLGFGAVGWVDDWRKVVHRDPKGLASRWKYFWTSAIALGASIFLGLSATTPAETEL
IVPFFKAVAYPLGVYGFIALTYFVINGTSHAVNLTDGLDGLAIMPTVMVAGALAIFAYVAGHAGFSKYLGVPYIAGAGEL
AVFCGAICGAGLGFLWFNAYPAEVFMGDVGALALGAALGTIAVVVRQEIVLFIMGGLFVAETLSVMVQVLYFKASGGKRI
FRMAPLHHHYELSGWKETQVVVRFWIITLMLVLFGLSTLKLR
>Mature_362_residues
MLLELALWLGQDIRGFNVFGYITLRTVLAALTALAISLTAGPGVIRWLAAKKIGQAVRDDGPKSHLTKAGTPTMGGALIL
IAIGITILLWGDLRNAYVWVTLLVTLGFGAVGWVDDWRKVVHRDPKGLASRWKYFWTSAIALGASIFLGLSATTPAETEL
IVPFFKAVAYPLGVYGFIALTYFVINGTSHAVNLTDGLDGLAIMPTVMVAGALAIFAYVAGHAGFSKYLGVPYIAGAGEL
AVFCGAICGAGLGFLWFNAYPAEVFMGDVGALALGAALGTIAVVVRQEIVLFIMGGLFVAETLSVMVQVLYFKASGGKRI
FRMAPLHHHYELSGWKETQVVVRFWIITLMLVLFGLSTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=362, Percent_Identity=60.4972375690608, Blast_Score=411, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 38802; Mature: 38802

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS01347 MRAY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLELALWLGQDIRGFNVFGYITLRTVLAALTALAISLTAGPGVIRWLAAKKIGQAVRDD
CCEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
GPKSHLTKAGTPTMGGALILIAIGITILLWGDLRNAYVWVTLLVTLGFGAVGWVDDWRKV
CCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
VHRDPKGLASRWKYFWTSAIALGASIFLGLSATTPAETELIVPFFKAVAYPLGVYGFIAL
HCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TYFVINGTSHAVNLTDGLDGLAIMPTVMVAGALAIFAYVAGHAGFSKYLGVPYIAGAGEL
HHHHEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEECCCCHH
AVFCGAICGAGLGFLWFNAYPAEVFMGDVGALALGAALGTIAVVVRQEIVLFIMGGLFVA
HHHHHHHHHCCHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETLSVMVQVLYFKASGGKRIFRMAPLHHHYELSGWKETQVVVRFWIITLMLVLFGLSTLK
HHHHHHHHHHHHCCCCCCEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCHHHHC
LR
CC
>Mature Secondary Structure
MLLELALWLGQDIRGFNVFGYITLRTVLAALTALAISLTAGPGVIRWLAAKKIGQAVRDD
CCEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
GPKSHLTKAGTPTMGGALILIAIGITILLWGDLRNAYVWVTLLVTLGFGAVGWVDDWRKV
CCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
VHRDPKGLASRWKYFWTSAIALGASIFLGLSATTPAETELIVPFFKAVAYPLGVYGFIAL
HCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TYFVINGTSHAVNLTDGLDGLAIMPTVMVAGALAIFAYVAGHAGFSKYLGVPYIAGAGEL
HHHHEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEECCCCHH
AVFCGAICGAGLGFLWFNAYPAEVFMGDVGALALGAALGTIAVVVRQEIVLFIMGGLFVA
HHHHHHHHHCCHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETLSVMVQVLYFKASGGKRIFRMAPLHHHYELSGWKETQVVVRFWIITLMLVLFGLSTLK
HHHHHHHHHHHHCCCCCCEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCHHHHC
LR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA