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The map label for this gene is glnS [H]

Identifier: 119897127

GI number: 119897127

Start: 894555

End: 896288

Strand: Reverse

Name: glnS [H]

Synonym: azo0836

Alternate gene names: 119897127

Gene position: 896288-894555 (Counterclockwise)

Preceding gene: 119897130

Following gene: 119897126

Centisome position: 20.48

GC content: 66.49

Gene sequence:

>1734_bases
ATGAATCCGAACGACAACAAGGACGGCGCGCCCGCCGCTCCCAGCAACTTCATCCGCAACCAGATCGACGAAGACAACCG
CAGCGGCAAGTGGAGCGGCCGCGTCGAGACGCGCTTCCCGCCCGAGCCCAACGGCTACCTGCACTACGGCCACGCCAAGT
CGATCTGCCTGAACTTCGGGCTGGCGGAAAGCTATGGCGGCGCCTGCCACCTGCGCTTCGACGACACCAACCCGGAGAAG
GAAGAGCAGGAATACGTCGATTCCATCATCGAGGCGGTGCAGTGGCTCGGCTTCGACTGGCGTGAGCACCTCTACTTCGC
CTCCGACTACTTCGACATCATGTACGCCTGCGCCGAATCGCTGATCAAGGCCGGCAAAGCCTATGTCGATTCGCTGTCGG
CCGAGGAAATGCGCGCGCTGCGCGGCACGCTGACCGAGCCGGGCAAGGACAGCCCGTTCCGCACCCGCAGCATCGACGAG
AACCTCGACCTCTTCCGCCGCATGCGCGCCGGCGAGTTCGCCGAAGGCACGCACGTCCTGCGCGCCAGGATCGACATGGC
GAGCCCCAACATCAACCTGCGCGATCCGGCGATCTACCGCATCCGCCGTGCCACCCACCACCGCACCGGCGACAACTGGT
GCATCTACCCGATGTACACCTTCGCGCACCCGATCGAGGACGCGATCGAGAACATCACCCATTCGATCTGCACGCTCGAA
TTCGAGGACCAGCGCCCGTTCTACGACTGGCTGCTCGACGCGCTCGCTTCCGCCGGCCACTTCCCACGCCCGCTGCCGCA
GCAGATCGAGTTCGCCCGCCTCAACCTCACCTACGTGGTGCTCTCCAAGCGCAAGCTGATCCAGCTGGTGGACGAAGGCC
ATGTGGACGGCTGGGACGACCCGCGCCTGCCCACGCTGGTCGGCGCGCGCCGCCGCGGCTTCACCGCCGAAGGCTTCCGC
CTGTTCGCAGAACGCATCGGCGTGACCAAGTCGGACTCCTGGATCGACATGAGCACGCTGGAAGAATGCATGCGCGAGCA
CCTCAACGAGGCCGCCGAACGCCGCGTCGCGGTGCTCGACCCGTTGAAGCTCGTCATCACCAACTACGCCGAAGGCGCCA
GCGAGCAGTGCCACGCGCCCAACCATCCGCTCAAGCCCGAACTCGGCAAGCGCGACATGCCCTTCGGCCGCGAGCTGTGG
ATCGAGCGCGAGGACTTCATGGAAGAGCCGGTGAAGGGCTTCCACCGCCTCTACCCCGGCAACACCGTGCGCCTGCGCTA
CGGCTACGTGGTGAAGTGCACCGGCTGCGAGAAGGACGCCGACGGCAACGTGACCGCCGTGCTCGCCGAATACATGGCGG
ACTCCAAGTCCGGCACGCCCGGCGCCGACAACTACAAGGTCAAGGGCAACCTGCACTGGGTGTCGGCCGCCCACGGCTAC
GCCGCCGAGATCCGCCTCTACGACCGCCTGTTCGCCCATCCGCACCCCGGCCAGCGCCGCGAGGGCGATCCCGAAGGCTA
CGAGCGCAGCTTCCTCGAAGACATCAACCCGGACTCCAAGCGCGTCATCCGCGCCTGGCTGGAACCCGCGCTGCGCGCCG
CCAAGCCGGAAGAACGCTTCCAGTTCGAACGCCACGGCTACTTCGTCGCCGACCGCCGCGACTCGGTGGACGGCGCGCCG
GTGTTCAACCGCACGGTGACGCTGAAGGATTCGTGGGCCAAGGGCGGAAAGTGA

Upstream 100 bases:

>100_bases
AACGCCGGCCGGACGGGCCGCTCTGCCCATCGGCTACAATTGCGCGCATTCGCAATCCGCATGCAACGCGGCGCCCCGCG
CCGCCGGGACTATCCGACCG

Downstream 100 bases:

>100_bases
AGCGTTTAAGCGCTCATCGCAGCGAGCCCCCCGGCCATTCCCCCTCCCCTTCAAGGGGAGGTTTGGGGTGGGGATGGGGT
GCTCGCCCCATACAAACGCC

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MNPNDNKDGAPAAPSNFIRNQIDEDNRSGKWSGRVETRFPPEPNGYLHYGHAKSICLNFGLAESYGGACHLRFDDTNPEK
EEQEYVDSIIEAVQWLGFDWREHLYFASDYFDIMYACAESLIKAGKAYVDSLSAEEMRALRGTLTEPGKDSPFRTRSIDE
NLDLFRRMRAGEFAEGTHVLRARIDMASPNINLRDPAIYRIRRATHHRTGDNWCIYPMYTFAHPIEDAIENITHSICTLE
FEDQRPFYDWLLDALASAGHFPRPLPQQIEFARLNLTYVVLSKRKLIQLVDEGHVDGWDDPRLPTLVGARRRGFTAEGFR
LFAERIGVTKSDSWIDMSTLEECMREHLNEAAERRVAVLDPLKLVITNYAEGASEQCHAPNHPLKPELGKRDMPFGRELW
IEREDFMEEPVKGFHRLYPGNTVRLRYGYVVKCTGCEKDADGNVTAVLAEYMADSKSGTPGADNYKVKGNLHWVSAAHGY
AAEIRLYDRLFAHPHPGQRREGDPEGYERSFLEDINPDSKRVIRAWLEPALRAAKPEERFQFERHGYFVADRRDSVDGAP
VFNRTVTLKDSWAKGGK

Sequences:

>Translated_577_residues
MNPNDNKDGAPAAPSNFIRNQIDEDNRSGKWSGRVETRFPPEPNGYLHYGHAKSICLNFGLAESYGGACHLRFDDTNPEK
EEQEYVDSIIEAVQWLGFDWREHLYFASDYFDIMYACAESLIKAGKAYVDSLSAEEMRALRGTLTEPGKDSPFRTRSIDE
NLDLFRRMRAGEFAEGTHVLRARIDMASPNINLRDPAIYRIRRATHHRTGDNWCIYPMYTFAHPIEDAIENITHSICTLE
FEDQRPFYDWLLDALASAGHFPRPLPQQIEFARLNLTYVVLSKRKLIQLVDEGHVDGWDDPRLPTLVGARRRGFTAEGFR
LFAERIGVTKSDSWIDMSTLEECMREHLNEAAERRVAVLDPLKLVITNYAEGASEQCHAPNHPLKPELGKRDMPFGRELW
IEREDFMEEPVKGFHRLYPGNTVRLRYGYVVKCTGCEKDADGNVTAVLAEYMADSKSGTPGADNYKVKGNLHWVSAAHGY
AAEIRLYDRLFAHPHPGQRREGDPEGYERSFLEDINPDSKRVIRAWLEPALRAAKPEERFQFERHGYFVADRRDSVDGAP
VFNRTVTLKDSWAKGGK
>Mature_577_residues
MNPNDNKDGAPAAPSNFIRNQIDEDNRSGKWSGRVETRFPPEPNGYLHYGHAKSICLNFGLAESYGGACHLRFDDTNPEK
EEQEYVDSIIEAVQWLGFDWREHLYFASDYFDIMYACAESLIKAGKAYVDSLSAEEMRALRGTLTEPGKDSPFRTRSIDE
NLDLFRRMRAGEFAEGTHVLRARIDMASPNINLRDPAIYRIRRATHHRTGDNWCIYPMYTFAHPIEDAIENITHSICTLE
FEDQRPFYDWLLDALASAGHFPRPLPQQIEFARLNLTYVVLSKRKLIQLVDEGHVDGWDDPRLPTLVGARRRGFTAEGFR
LFAERIGVTKSDSWIDMSTLEECMREHLNEAAERRVAVLDPLKLVITNYAEGASEQCHAPNHPLKPELGKRDMPFGRELW
IEREDFMEEPVKGFHRLYPGNTVRLRYGYVVKCTGCEKDADGNVTAVLAEYMADSKSGTPGADNYKVKGNLHWVSAAHGY
AAEIRLYDRLFAHPHPGQRREGDPEGYERSFLEDINPDSKRVIRAWLEPALRAAKPEERFQFERHGYFVADRRDSVDGAP
VFNRTVTLKDSWAKGGK

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=545, Percent_Identity=45.3211009174312, Blast_Score=413, Evalue=1e-115,
Organism=Homo sapiens, GI62241042, Length=527, Percent_Identity=33.3965844402277, Blast_Score=277, Evalue=2e-74,
Organism=Escherichia coli, GI1786895, Length=568, Percent_Identity=57.0422535211268, Blast_Score=647, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=108, Percent_Identity=34.2592592592593, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17543332, Length=548, Percent_Identity=42.5182481751825, Blast_Score=403, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17511007, Length=530, Percent_Identity=32.6415094339623, Blast_Score=254, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6324742, Length=580, Percent_Identity=40.5172413793103, Blast_Score=385, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6321192, Length=543, Percent_Identity=34.4383057090239, Blast_Score=271, Evalue=2e-73,
Organism=Drosophila melanogaster, GI17864488, Length=544, Percent_Identity=41.3602941176471, Blast_Score=398, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24649466, Length=527, Percent_Identity=34.1555977229602, Blast_Score=266, Evalue=2e-71,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 66011; Mature: 66011

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPNDNKDGAPAAPSNFIRNQIDEDNRSGKWSGRVETRFPPEPNGYLHYGHAKSICLNFG
CCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCEEEECCHHHHHEECC
LAESYGGACHLRFDDTNPEKEEQEYVDSIIEAVQWLGFDWREHLYFASDYFDIMYACAES
CHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHEEHHHHHHHHHHHHHHH
LIKAGKAYVDSLSAEEMRALRGTLTEPGKDSPFRTRSIDENLDLFRRMRAGEFAEGTHVL
HHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHH
RARIDMASPNINLRDPAIYRIRRATHHRTGDNWCIYPMYTFAHPIEDAIENITHSICTLE
HEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEHHHHHCHHHHHHHHHHHHHEEEE
FEDQRPFYDWLLDALASAGHFPRPLPQQIEFARLNLTYVVLSKRKLIQLVDEGHVDGWDD
ECCCCCHHHHHHHHHHHCCCCCCCCCHHHHEEHEEEEEEEECHHHHHHHHHCCCCCCCCC
PRLPTLVGARRRGFTAEGFRLFAERIGVTKSDSWIDMSTLEECMREHLNEAAERRVAVLD
CCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCHHHC
PLKLVITNYAEGASEQCHAPNHPLKPELGKRDMPFGRELWIEREDFMEEPVKGFHRLYPG
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCC
NTVRLRYGYVVKCTGCEKDADGNVTAVLAEYMADSKSGTPGADNYKVKGNLHWVSAAHGY
CEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEECEEEEEECCCCC
AAEIRLYDRLFAHPHPGQRREGDPEGYERSFLEDINPDSKRVIRAWLEPALRAAKPEERF
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHH
QFERHGYFVADRRDSVDGAPVFNRTVTLKDSWAKGGK
HHHHCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MNPNDNKDGAPAAPSNFIRNQIDEDNRSGKWSGRVETRFPPEPNGYLHYGHAKSICLNFG
CCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCEEEECCHHHHHEECC
LAESYGGACHLRFDDTNPEKEEQEYVDSIIEAVQWLGFDWREHLYFASDYFDIMYACAES
CHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHEEHHHHHHHHHHHHHHH
LIKAGKAYVDSLSAEEMRALRGTLTEPGKDSPFRTRSIDENLDLFRRMRAGEFAEGTHVL
HHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHH
RARIDMASPNINLRDPAIYRIRRATHHRTGDNWCIYPMYTFAHPIEDAIENITHSICTLE
HEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEHHHHHCHHHHHHHHHHHHHEEEE
FEDQRPFYDWLLDALASAGHFPRPLPQQIEFARLNLTYVVLSKRKLIQLVDEGHVDGWDD
ECCCCCHHHHHHHHHHHCCCCCCCCCHHHHEEHEEEEEEEECHHHHHHHHHCCCCCCCCC
PRLPTLVGARRRGFTAEGFRLFAERIGVTKSDSWIDMSTLEECMREHLNEAAERRVAVLD
CCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCHHHC
PLKLVITNYAEGASEQCHAPNHPLKPELGKRDMPFGRELWIEREDFMEEPVKGFHRLYPG
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCC
NTVRLRYGYVVKCTGCEKDADGNVTAVLAEYMADSKSGTPGADNYKVKGNLHWVSAAHGY
CEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEECEEEEEECCCCC
AAEIRLYDRLFAHPHPGQRREGDPEGYERSFLEDINPDSKRVIRAWLEPALRAAKPEERF
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHH
QFERHGYFVADRRDSVDGAPVFNRTVTLKDSWAKGGK
HHHHCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA