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The map label for this gene is allR [H]

Identifier: 119897115

GI number: 119897115

Start: 882604

End: 883407

Strand: Reverse

Name: allR [H]

Synonym: azo0824

Alternate gene names: 119897115

Gene position: 883407-882604 (Counterclockwise)

Preceding gene: 119897120

Following gene: 119897111

Centisome position: 20.19

GC content: 67.66

Gene sequence:

>804_bases
GTGGTCGTCAAGAAGCCAGAACCTACCCCCGCGGCAGAAGCCAAGAACCCCATCCAGGTCATCGAGCGCATGATGAAGCT
GCTCGACGTGCTCGCGCATCACGCCGATCCGGTGCCGCTGAAGCAGCTCGCACTGGAAACCGGGCTTCACCCCTCCACCG
CACACCGCATCCTGGGTGCGATGACCCAGAGCGGCTTTGTCGAGCGCTCTGACGCCGGCGTCTACCGCCTCGGCATTCGA
TTGCTGGAACTCGGCAGCCTGGTGAAGTCGCGCATCTCGCTGCGCGAGACCGCCATGCCGGCGATGCTCAAGCTGCATGC
CACGACAGGCGAAAGCGTCAACCTCGGCATCCGCGCCGGCGACGAGATCGTCTATGTGGAGCGCACGTCGAGCGGCCGGT
CCTCGGTGCGGGTCGTGCATATCGTCGGCGCGCGCGCCCCGCTGCATACCACCGCCACCGGCAAGCTCTTCCTCGTCGAG
GACGGTCTGGAAAGAGTCCGCGACTACGCCCGGCGCACCGGCCTGCCGGCGTCCACCTCCGCCTCCATCACCACGCTGCC
GCTGCTGGAAAAGGAACTCGACAAGGTGCGCCGTCACGCGGTGGCCTTCGACCTCGATGAAGTCGAGGCCGGCGTCCGCT
GCATTGCGGCCGGCATCCGCGACGACAGCGGCGAGCTGATCGCCGGGTTGTCGCTGTCCACGCCGTCGGAGCGCTTCAAC
CCCGACTGGGCACCGCTGGTGCGCGATACCGCCGACGAGATTTCGCAGGCGCTCGGCTGGCGCCAACGCCGCACGGCGAC
GTAA

Upstream 100 bases:

>100_bases
ATTCCCTCTCCCCGTCCAGGCCCGCGCCTTTTCATTTCACTAGGCGAAATTAAGCCGCCCGGTTACCATTCGCAAGTTAC
GGAAAACCCTCAAATATCCA

Downstream 100 bases:

>100_bases
ACGGCGAAGCGCTCCGGAGAGCGCTTCGTGTTGTAACGGTAAGGCCGGTCGCCCGCAGGCGTTCAGCTGTCGCGCCGCGC
CGCCGCGGTGGCCACGTGCG

Product: negative regulator of allantoin and glyoxylate utilization operons

Products: NA

Alternate protein names: Negative regulator of allantoin and glyoxylate utilization operons [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MVVKKPEPTPAAEAKNPIQVIERMMKLLDVLAHHADPVPLKQLALETGLHPSTAHRILGAMTQSGFVERSDAGVYRLGIR
LLELGSLVKSRISLRETAMPAMLKLHATTGESVNLGIRAGDEIVYVERTSSGRSSVRVVHIVGARAPLHTTATGKLFLVE
DGLERVRDYARRTGLPASTSASITTLPLLEKELDKVRRHAVAFDLDEVEAGVRCIAAGIRDDSGELIAGLSLSTPSERFN
PDWAPLVRDTADEISQALGWRQRRTAT

Sequences:

>Translated_267_residues
MVVKKPEPTPAAEAKNPIQVIERMMKLLDVLAHHADPVPLKQLALETGLHPSTAHRILGAMTQSGFVERSDAGVYRLGIR
LLELGSLVKSRISLRETAMPAMLKLHATTGESVNLGIRAGDEIVYVERTSSGRSSVRVVHIVGARAPLHTTATGKLFLVE
DGLERVRDYARRTGLPASTSASITTLPLLEKELDKVRRHAVAFDLDEVEAGVRCIAAGIRDDSGELIAGLSLSTPSERFN
PDWAPLVRDTADEISQALGWRQRRTAT
>Mature_267_residues
MVVKKPEPTPAAEAKNPIQVIERMMKLLDVLAHHADPVPLKQLALETGLHPSTAHRILGAMTQSGFVERSDAGVYRLGIR
LLELGSLVKSRISLRETAMPAMLKLHATTGESVNLGIRAGDEIVYVERTSSGRSSVRVVHIVGARAPLHTTATGKLFLVE
DGLERVRDYARRTGLPASTSASITTLPLLEKELDKVRRHAVAFDLDEVEAGVRCIAAGIRDDSGELIAGLSLSTPSERFN
PDWAPLVRDTADEISQALGWRQRRTAT

Specific function: Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786715, Length=253, Percent_Identity=31.6205533596838, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1789999, Length=271, Percent_Identity=28.4132841328413, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082359, Length=269, Percent_Identity=29.368029739777, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786468, Length=248, Percent_Identity=29.4354838709677, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788131, Length=228, Percent_Identity=30.7017543859649, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790752, Length=215, Percent_Identity=26.046511627907, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788581, Length=245, Percent_Identity=25.7142857142857, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29044; Mature: 29044

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVKKPEPTPAAEAKNPIQVIERMMKLLDVLAHHADPVPLKQLALETGLHPSTAHRILGA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHH
MTQSGFVERSDAGVYRLGIRLLELGSLVKSRISLRETAMPAMLKLHATTGESVNLGIRAG
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCCCCEEEEEECC
DEIVYVERTSSGRSSVRVVHIVGARAPLHTTATGKLFLVEDGLERVRDYARRTGLPASTS
CEEEEEEECCCCCCCEEEEEEEECCCCCEECCCCEEEEEHHHHHHHHHHHHHCCCCCCCC
ASITTLPLLEKELDKVRRHAVAFDLDEVEAGVRCIAAGIRDDSGELIAGLSLSTPSERFN
CCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHCC
PDWAPLVRDTADEISQALGWRQRRTAT
CCHHHHHHHHHHHHHHHHCCHHHCCCC
>Mature Secondary Structure
MVVKKPEPTPAAEAKNPIQVIERMMKLLDVLAHHADPVPLKQLALETGLHPSTAHRILGA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHH
MTQSGFVERSDAGVYRLGIRLLELGSLVKSRISLRETAMPAMLKLHATTGESVNLGIRAG
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCCCCEEEEEECC
DEIVYVERTSSGRSSVRVVHIVGARAPLHTTATGKLFLVEDGLERVRDYARRTGLPASTS
CEEEEEEECCCCCCCEEEEEEEECCCCCEECCCCEEEEEHHHHHHHHHHHHHCCCCCCCC
ASITTLPLLEKELDKVRRHAVAFDLDEVEAGVRCIAAGIRDDSGELIAGLSLSTPSERFN
CCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHCC
PDWAPLVRDTADEISQALGWRQRRTAT
CCHHHHHHHHHHHHHHHHCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA