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The map label for this gene is murA [H]

Identifier: 119897106

GI number: 119897106

Start: 870517

End: 871767

Strand: Direct

Name: murA [H]

Synonym: azo0815

Alternate gene names: 119897106

Gene position: 870517-871767 (Clockwise)

Preceding gene: 119897105

Following gene: 119897108

Centisome position: 19.89

GC content: 68.27

Gene sequence:

>1251_bases
ATGGACAAGTTGTTGATTGAAGGCGGCCGCCGGCTTTCCGGCGAAGTTGCCATTTCCGGCGCCAAGAACGCGGCGCTGCC
CATCCTGTGCGCCGCCCTGCTGACGCGCGAACCGGTTACGTTCACCAACGTGCCGCGCCTGAACGACATCGGCACGCTGC
TCAAGCTGCTGGGTCAGATGGGCGTCAAGGTGGAGCGCGAAGACGATCGCGTGACCCTCGACGCTTCTGCGCTCGACAAT
CCGGTCGCCCCGTACGAGATGGTCAAGACCATGCGGGCGTCGATCCTGGTGCTTGGCCCGCTGGTGGCGCGCTGTGGCGA
TGCGCGGGTGTCGCTGCCCGGCGGCTGCGCGATCGGCGCCCGCCCGGTTGACCAGCACATCAAGGGCCTGCAGGCGATGG
GCGCCGAAGTGCGTGTCGAACACGGCTACGTGCAGGCCCAGGTGCCGCGGCTCAAGGGGGCCCGGCTGTTCACCGACATG
GTGACCGTGACCGGCACCGAGAACCTGATGATGGCGGCCTGCCTGGCGCAGGGCGAAACCGTCATCGAAAATGCCGCGCG
CGAGCCCGAGGTCGTCGACCTGGCCAACTGTCTGGTGGCCATGGGCGCCCAGATCTCCGGCGCCGGGACCGACGTGATCC
GCATCCGCGGCGTCGACGCGCTGCACGGCGCCACTCACCGCATCATGCCGGATCGCATCGAAACGGGAACGTATCTCTGT
GCCGCAGCCGTAACCGGCGGTGAAGTGCGTCTCACCGGCACTTCGTCGTGCTACCTGGATGCGGTGATCGACAAGCTGAT
GGATGCCGGTTGCGAAGTCGTCTCCGAGCGCGACGCGATCCGCCTCGCGGCGCCGCGCCGCCCGCAGGCGGTGAACCTGC
GCACGGCGCCGTATCCGGCTTTTCCCACCGACATGCAGGCGCAGTTCATGGCGCTCAACTGCGTGGCCGACGGGGCGGCG
ATGATCCGCGAGACCATCTTCGAGAACCGCTTCATGCACGCGGTGGAACTGCAGCGTCTCGGCGCGGACATCCGCATCGA
CGGCAACACCGCGGTGGTGCGCGGCGTGGAGCGCTTGCAGGGCGCCACGGTGATGGCGACCGACCTGCGCGCTTCCGCCA
GCCTGGTCGTTGCCGGCCTGGTGGCCGAGGGCGAGACGGTGATCGAACGGATCTACCACCTCGACCGCGGCTACGAGCGG
CTCGAAGAAAAGCTCGCCGCGCTCGGCGCCAGCGTCCGCCGGCTGAGTTGA

Upstream 100 bases:

>100_bases
CCTGCAGCTGCAGACCTATACGCCCGCCAAGTGGGAAACGGTGCGCGGCGAGCTGGGCCTGTAAAAGGCCGGCGGCCGCC
GGCCCGTCATTCGAGGTTTC

Downstream 100 bases:

>100_bases
GCCTGCGACCGGCCCCGCGGCCGGTCGCCCCTCACAGCGCGAGGCAGCCCGCCGCCTCGGGCTGCCACACCACTTCCAGC
ACCTGCAGACGGATCGCGCT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MDKLLIEGGRRLSGEVAISGAKNAALPILCAALLTREPVTFTNVPRLNDIGTLLKLLGQMGVKVEREDDRVTLDASALDN
PVAPYEMVKTMRASILVLGPLVARCGDARVSLPGGCAIGARPVDQHIKGLQAMGAEVRVEHGYVQAQVPRLKGARLFTDM
VTVTGTENLMMAACLAQGETVIENAAREPEVVDLANCLVAMGAQISGAGTDVIRIRGVDALHGATHRIMPDRIETGTYLC
AAAVTGGEVRLTGTSSCYLDAVIDKLMDAGCEVVSERDAIRLAAPRRPQAVNLRTAPYPAFPTDMQAQFMALNCVADGAA
MIRETIFENRFMHAVELQRLGADIRIDGNTAVVRGVERLQGATVMATDLRASASLVVAGLVAEGETVIERIYHLDRGYER
LEEKLAALGASVRRLS

Sequences:

>Translated_416_residues
MDKLLIEGGRRLSGEVAISGAKNAALPILCAALLTREPVTFTNVPRLNDIGTLLKLLGQMGVKVEREDDRVTLDASALDN
PVAPYEMVKTMRASILVLGPLVARCGDARVSLPGGCAIGARPVDQHIKGLQAMGAEVRVEHGYVQAQVPRLKGARLFTDM
VTVTGTENLMMAACLAQGETVIENAAREPEVVDLANCLVAMGAQISGAGTDVIRIRGVDALHGATHRIMPDRIETGTYLC
AAAVTGGEVRLTGTSSCYLDAVIDKLMDAGCEVVSERDAIRLAAPRRPQAVNLRTAPYPAFPTDMQAQFMALNCVADGAA
MIRETIFENRFMHAVELQRLGADIRIDGNTAVVRGVERLQGATVMATDLRASASLVVAGLVAEGETVIERIYHLDRGYER
LEEKLAALGASVRRLS
>Mature_416_residues
MDKLLIEGGRRLSGEVAISGAKNAALPILCAALLTREPVTFTNVPRLNDIGTLLKLLGQMGVKVEREDDRVTLDASALDN
PVAPYEMVKTMRASILVLGPLVARCGDARVSLPGGCAIGARPVDQHIKGLQAMGAEVRVEHGYVQAQVPRLKGARLFTDM
VTVTGTENLMMAACLAQGETVIENAAREPEVVDLANCLVAMGAQISGAGTDVIRIRGVDALHGATHRIMPDRIETGTYLC
AAAVTGGEVRLTGTSSCYLDAVIDKLMDAGCEVVSERDAIRLAAPRRPQAVNLRTAPYPAFPTDMQAQFMALNCVADGAA
MIRETIFENRFMHAVELQRLGADIRIDGNTAVVRGVERLQGATVMATDLRASASLVVAGLVAEGETVIERIYHLDRGYER
LEEKLAALGASVRRLS

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=59.0909090909091, Blast_Score=481, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44392; Mature: 44392

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00185 IPNS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLLIEGGRRLSGEVAISGAKNAALPILCAALLTREPVTFTNVPRLNDIGTLLKLLGQM
CCCCEECCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
GVKVEREDDRVTLDASALDNPVAPYEMVKTMRASILVLGPLVARCGDARVSLPGGCAIGA
CCEEEECCCCEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
RPVDQHIKGLQAMGAEVRVEHGYVQAQVPRLKGARLFTDMVTVTGTENLMMAACLAQGET
CCHHHHHHHHHHCCCEEEEECCEEEEECCCCCCCCCEEHHEEECCCCHHHHHHHHHCCCH
VIENAAREPEVVDLANCLVAMGAQISGAGTDVIRIRGVDALHGATHRIMPDRIETGTYLC
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHCCHHCCCCCCCCCCCEEE
AAAVTGGEVRLTGTSSCYLDAVIDKLMDAGCEVVSERDAIRLAAPRRPQAVNLRTAPYPA
EEEECCCEEEEECCCHHHHHHHHHHHHHCCHHHHCCCCCEEEECCCCCCEEEEECCCCCC
FPTDMQAQFMALNCVADGAAMIRETIFENRFMHAVELQRLGADIRIDGNTAVVRGVERLQ
CCCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHC
GATVMATDLRASASLVVAGLVAEGETVIERIYHLDRGYERLEEKLAALGASVRRLS
CCEEEEECHHCCHHEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDKLLIEGGRRLSGEVAISGAKNAALPILCAALLTREPVTFTNVPRLNDIGTLLKLLGQM
CCCCEECCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
GVKVEREDDRVTLDASALDNPVAPYEMVKTMRASILVLGPLVARCGDARVSLPGGCAIGA
CCEEEECCCCEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
RPVDQHIKGLQAMGAEVRVEHGYVQAQVPRLKGARLFTDMVTVTGTENLMMAACLAQGET
CCHHHHHHHHHHCCCEEEEECCEEEEECCCCCCCCCEEHHEEECCCCHHHHHHHHHCCCH
VIENAAREPEVVDLANCLVAMGAQISGAGTDVIRIRGVDALHGATHRIMPDRIETGTYLC
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHCCHHCCCCCCCCCCCEEE
AAAVTGGEVRLTGTSSCYLDAVIDKLMDAGCEVVSERDAIRLAAPRRPQAVNLRTAPYPA
EEEECCCEEEEECCCHHHHHHHHHHHHHCCHHHHCCCCCEEEECCCCCCEEEEECCCCCC
FPTDMQAQFMALNCVADGAAMIRETIFENRFMHAVELQRLGADIRIDGNTAVVRGVERLQ
CCCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHC
GATVMATDLRASASLVVAGLVAEGETVIERIYHLDRGYERLEEKLAALGASVRRLS
CCEEEEECHHCCHHEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA