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The map label for this gene is corC [H]

Identifier: 119897072

GI number: 119897072

Start: 836270

End: 837115

Strand: Direct

Name: corC [H]

Synonym: azo0781

Alternate gene names: 119897072

Gene position: 836270-837115 (Clockwise)

Preceding gene: 228906475

Following gene: 119897073

Centisome position: 19.11

GC content: 65.13

Gene sequence:

>846_bases
ATGGATAGTGTCCCTAGTAAACCGACCCTGCTCGAACGGCTGTCTTCCATGCTCTCGCGAGAGCCGGAAGACCGCGACGA
GTTGCTGGTCCTGCTGCACGCCGCGCTCGAGCGCGGCCTGCTCGATGCCGACGCCTTCTCGATCATCGAGGGCGCGTTGC
AGGTTTCCGAACTCCAGGTCCGCGACGTGATGGTGTCGCGCTCGCGCATGGATGTCATCCGCCTCGCCGACCCCATGGAG
CGCATCGCCGAGTTCGTCATCGATACCGCGCATTCGCGCTTTCCGGCGGTGGGTGAAAGCAAGGACGACGTGGTCGGCAT
CCTGCTGGCCAAGGACCTGTTGCGCTACTTCGCCGGGCGTGAATTCAACCTGCGCGAAATGCTGCGGCCGGCCGTGTTCG
TGCCGGAGTCCAAGCGCCTCAACGTGCTGCTGCGCGAATTCCGCGTCAGCCACAATCATATGGCCATCGTCGTCGATGAG
TACGGCGGCGTCTCCGGCCTGATCACCATCGAAGACGTGCTCGAACAGATCGTCGGTGACATCGAGGACGAGTACGACTT
CGACGAGATCGGCGCGCGCATCCGGCTGGATCACAAGGGCCGCTACCGGGTGCAGGCGAGCACCGAGATCGAGGACTTCA
ATGCGGCCTTCGGCACCCGCTGCCATGAGGAGGACGTCGATACCATCGGCGGCCTGATCCTGCGGCGGCTCGGGCGCCTG
CCGGTGCGCGGCGAGGTGATCGACGTCGACGGGCTGCGGGTGCAGGTCCTGCGCGCCGACAGCCGTCGCATCCACACCTT
GCTGGTCGAGCGTCTGCCGCAGGTTTCCGACGTGACGGCGAACTGA

Upstream 100 bases:

>100_bases
CCTGAGGAGGCACGCGGGAAGATCGAGGATTTGGGAGCGTACGTAACACGCATGAAACTTGCTCGGTCCCAAATCCTGGT
TCTTGTCTACCGCACCCTAC

Downstream 100 bases:

>100_bases
TGCGGCGCCTGGTGCTGGCCGCGCTGGCGGGCGCGACGCTTACGCCCGCGCTGGCGCCGTTCGAACTGTTTCCGCTCGCC
CTCGTGAGCCTGGCCGGGCT

Product: putative magnesium and cobalt efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MDSVPSKPTLLERLSSMLSREPEDRDELLVLLHAALERGLLDADAFSIIEGALQVSELQVRDVMVSRSRMDVIRLADPME
RIAEFVIDTAHSRFPAVGESKDDVVGILLAKDLLRYFAGREFNLREMLRPAVFVPESKRLNVLLREFRVSHNHMAIVVDE
YGGVSGLITIEDVLEQIVGDIEDEYDFDEIGARIRLDHKGRYRVQASTEIEDFNAAFGTRCHEEDVDTIGGLILRRLGRL
PVRGEVIDVDGLRVQVLRADSRRIHTLLVERLPQVSDVTAN

Sequences:

>Translated_281_residues
MDSVPSKPTLLERLSSMLSREPEDRDELLVLLHAALERGLLDADAFSIIEGALQVSELQVRDVMVSRSRMDVIRLADPME
RIAEFVIDTAHSRFPAVGESKDDVVGILLAKDLLRYFAGREFNLREMLRPAVFVPESKRLNVLLREFRVSHNHMAIVVDE
YGGVSGLITIEDVLEQIVGDIEDEYDFDEIGARIRLDHKGRYRVQASTEIEDFNAAFGTRCHEEDVDTIGGLILRRLGRL
PVRGEVIDVDGLRVQVLRADSRRIHTLLVERLPQVSDVTAN
>Mature_281_residues
MDSVPSKPTLLERLSSMLSREPEDRDELLVLLHAALERGLLDADAFSIIEGALQVSELQVRDVMVSRSRMDVIRLADPME
RIAEFVIDTAHSRFPAVGESKDDVVGILLAKDLLRYFAGREFNLREMLRPAVFVPESKRLNVLLREFRVSHNHMAIVVDE
YGGVSGLITIEDVLEQIVGDIEDEYDFDEIGARIRLDHKGRYRVQASTEIEDFNAAFGTRCHEEDVDTIGGLILRRLGRL
PVRGEVIDVDGLRVQVLRADSRRIHTLLVERLPQVSDVTAN

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=239, Percent_Identity=24.2677824267782, Blast_Score=98, Evalue=8e-21,
Organism=Escherichia coli, GI1786879, Length=266, Percent_Identity=44.3609022556391, Blast_Score=218, Evalue=3e-58,
Organism=Escherichia coli, GI87082033, Length=223, Percent_Identity=30.9417040358744, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693175, Length=212, Percent_Identity=30.6603773584906, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790664, Length=261, Percent_Identity=24.5210727969349, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788119, Length=220, Percent_Identity=29.0909090909091, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 31751; Mature: 31751

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSVPSKPTLLERLSSMLSREPEDRDELLVLLHAALERGLLDADAFSIIEGALQVSELQV
CCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
RDVMVSRSRMDVIRLADPMERIAEFVIDTAHSRFPAVGESKDDVVGILLAKDLLRYFAGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC
EFNLREMLRPAVFVPESKRLNVLLREFRVSHNHMAIVVDEYGGVSGLITIEDVLEQIVGD
CCCHHHHHCCCEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHHHHHHH
IEDEYDFDEIGARIRLDHKGRYRVQASTEIEDFNAAFGTRCHEEDVDTIGGLILRRLGRL
CCCCCCHHHCCCEEEECCCCCEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
PVRGEVIDVDGLRVQVLRADSRRIHTLLVERLPQVSDVTAN
CCCCEEEECCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDSVPSKPTLLERLSSMLSREPEDRDELLVLLHAALERGLLDADAFSIIEGALQVSELQV
CCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
RDVMVSRSRMDVIRLADPMERIAEFVIDTAHSRFPAVGESKDDVVGILLAKDLLRYFAGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC
EFNLREMLRPAVFVPESKRLNVLLREFRVSHNHMAIVVDEYGGVSGLITIEDVLEQIVGD
CCCHHHHHCCCEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHHHHHHH
IEDEYDFDEIGARIRLDHKGRYRVQASTEIEDFNAAFGTRCHEEDVDTIGGLILRRLGRL
CCCCCCHHHCCCEEEECCCCCEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
PVRGEVIDVDGLRVQVLRADSRRIHTLLVERLPQVSDVTAN
CCCCEEEECCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]