Click here to switch to the map view.

The map label for this gene is gluQ [H]

Identifier: 119897036

GI number: 119897036

Start: 795366

End: 796367

Strand: Reverse

Name: gluQ [H]

Synonym: azo0745

Alternate gene names: 119897036

Gene position: 796367-795366 (Counterclockwise)

Preceding gene: 119897039

Following gene: 119897035

Centisome position: 18.2

GC content: 74.65

Gene sequence:

>1002_bases
ATGCGGCGCCAACCCGGCGCCCGCAGCACGCGGGCACCGCCGTCCGCTGGCCGCCTGCCGATGACCGCCGCCGATACCGC
TCCCGTCCCGCGTCCCGTTCCGCCGGCGCCCGCGCGCTATGTCGGCCGCTTTGCGCCCTCCCCCACCGGCCCCCTGCATT
TCGGCTCGCTCGTTGCCGCTGCCGCGAGCTGGCTGGAGGCCCAGGCCCACGACGGGCGCTGGCTGCTGCGCATCGAGGAT
GTGGACGCGCCGCGCTGTGTGCCTGGCGCAGCCGCGGACATCCTCGCCACGCTCGACCGTTTCGGCTTCCGGTGGGACGG
GGAGGTGGTGTACCAGAGTACGCGCACCGCAGCCTACGAAGCGGCGCTCGAACACCTGCGCAGCAGCGAGCACGCCTTTC
CCTGCGGTTGCACGCGCGCCGAACTCGCCGCCGCACCGCTTGCCCGCGACGGCTCGCGCCGCTACCCGGGCACCTGCCGC
AACGGCCTCGCCCCAGGGCGCGGCGCGCGCGCCTGGCGGGTGCGGGCGGAAGGCGTGGTGCGCTTCGAAGACGGCGTACA
GGGCTGGCAGGAGGAGGATCTCGCGCGCGACTGCGGCGACTATGTGGTACGGCGCGCCGACGGGTTGTTCGCCTACCAGC
TCGCGGTCGTGGTGGACGATGCCGCAGCCGGCGTCACCCACGTCGTGCGCGGTGCCGACCTGCTCGATTCCACCGCGCGC
CAGATCCATCTCCACCGCCTGCTGGGCAGTGCCGCGCCGGCGCATGCCCATGTGCCCGTGGCCACCAACGCCGCCGGCGA
GAAGCTGTCGAAGCAGACCCACGCGCTCGCGCTCGATCCCGCCGCTCCGGCGCCCGCGCTGCTGGCGGCGCTGGCCTTTC
TCGGCCAGAATCCCCCGCCAGAACTTGCGCGCGCCACGCCGGCGGAGGTATGGGCATGGGCGCGCATGCACTGGCACCTT
GCCGGCGTGCCCCGCCAGCGCCACGCGCCGGCTCCAGCCTGA

Upstream 100 bases:

>100_bases
GCAGAAGAAAACAGGGTGAAGGGAGGGCCGCCGCGCCCTCGATGAGTGCGCCGCGAGGGCGGACCGGCGCGCAGCCGGGC
AGGCGGCGGCGAATGCTATC

Downstream 100 bases:

>100_bases
GGACCCACACATGCCAGCCACCCCGCAAGGACAGTTCATCGACGACATCGCCGGCCTGCGCCGCGTGCTGCAGCAGACCC
GCAGCATCGCCGTGGTGGGC

Product: glutamate-tRNA ligase

Products: NA

Alternate protein names: Glu-Q-RSs [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MRRQPGARSTRAPPSAGRLPMTAADTAPVPRPVPPAPARYVGRFAPSPTGPLHFGSLVAAAASWLEAQAHDGRWLLRIED
VDAPRCVPGAAADILATLDRFGFRWDGEVVYQSTRTAAYEAALEHLRSSEHAFPCGCTRAELAAAPLARDGSRRYPGTCR
NGLAPGRGARAWRVRAEGVVRFEDGVQGWQEEDLARDCGDYVVRRADGLFAYQLAVVVDDAAAGVTHVVRGADLLDSTAR
QIHLHRLLGSAAPAHAHVPVATNAAGEKLSKQTHALALDPAAPAPALLAALAFLGQNPPPELARATPAEVWAWARMHWHL
AGVPRQRHAPAPA

Sequences:

>Translated_333_residues
MRRQPGARSTRAPPSAGRLPMTAADTAPVPRPVPPAPARYVGRFAPSPTGPLHFGSLVAAAASWLEAQAHDGRWLLRIED
VDAPRCVPGAAADILATLDRFGFRWDGEVVYQSTRTAAYEAALEHLRSSEHAFPCGCTRAELAAAPLARDGSRRYPGTCR
NGLAPGRGARAWRVRAEGVVRFEDGVQGWQEEDLARDCGDYVVRRADGLFAYQLAVVVDDAAAGVTHVVRGADLLDSTAR
QIHLHRLLGSAAPAHAHVPVATNAAGEKLSKQTHALALDPAAPAPALLAALAFLGQNPPPELARATPAEVWAWARMHWHL
AGVPRQRHAPAPA
>Mature_333_residues
MRRQPGARSTRAPPSAGRLPMTAADTAPVPRPVPPAPARYVGRFAPSPTGPLHFGSLVAAAASWLEAQAHDGRWLLRIED
VDAPRCVPGAAADILATLDRFGFRWDGEVVYQSTRTAAYEAALEHLRSSEHAFPCGCTRAELAAAPLARDGSRRYPGTCR
NGLAPGRGARAWRVRAEGVVRFEDGVQGWQEEDLARDCGDYVVRRADGLFAYQLAVVVDDAAAGVTHVVRGADLLDSTAR
QIHLHRLLGSAAPAHAHVPVATNAAGEKLSKQTHALALDPAAPAPALLAALAFLGQNPPPELARATPAEVWAWARMHWHL
AGVPRQRHAPAPA

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=256, Percent_Identity=38.28125, Blast_Score=144, Evalue=8e-35,
Organism=Escherichia coli, GI226510925, Length=290, Percent_Identity=46.8965517241379, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1788743, Length=264, Percent_Identity=35.6060606060606, Blast_Score=149, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71993394, Length=248, Percent_Identity=31.8548387096774, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324540, Length=316, Percent_Identity=30.6962025316456, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24665321, Length=254, Percent_Identity=34.6456692913386, Blast_Score=124, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: NA

Molecular weight: Translated: 35483; Mature: 35483

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS00436 PEROXIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRQPGARSTRAPPSAGRLPMTAADTAPVPRPVPPAPARYVGRFAPSPTGPLHFGSLVAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHH
AASWLEAQAHDGRWLLRIEDVDAPRCVPGAAADILATLDRFGFRWDGEVVYQSTRTAAYE
HHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHH
AALEHLRSSEHAFPCGCTRAELAAAPLARDGSRRYPGTCRNGLAPGRGARAWRVRAEGVV
HHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCCCEEEEECCCEE
RFEDGVQGWQEEDLARDCGDYVVRRADGLFAYQLAVVVDDAAAGVTHVVRGADLLDSTAR
EEHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHH
QIHLHRLLGSAAPAHAHVPVATNAAGEKLSKQTHALALDPAAPAPALLAALAFLGQNPPP
HHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHCCCCCH
ELARATPAEVWAWARMHWHLAGVPRQRHAPAPA
HHHHCCHHHHHHHHHHHEEECCCCHHCCCCCCC
>Mature Secondary Structure
MRRQPGARSTRAPPSAGRLPMTAADTAPVPRPVPPAPARYVGRFAPSPTGPLHFGSLVAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHH
AASWLEAQAHDGRWLLRIEDVDAPRCVPGAAADILATLDRFGFRWDGEVVYQSTRTAAYE
HHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHH
AALEHLRSSEHAFPCGCTRAELAAAPLARDGSRRYPGTCRNGLAPGRGARAWRVRAEGVV
HHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCCCEEEEECCCEE
RFEDGVQGWQEEDLARDCGDYVVRRADGLFAYQLAVVVDDAAAGVTHVVRGADLLDSTAR
EEHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHH
QIHLHRLLGSAAPAHAHVPVATNAAGEKLSKQTHALALDPAAPAPALLAALAFLGQNPPP
HHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHCCCCCH
ELARATPAEVWAWARMHWHLAGVPRQRHAPAPA
HHHHCCHHHHHHHHHHHEEECCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA