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The map label for this gene is nudG [C]

Identifier: 119897019

GI number: 119897019

Start: 780242

End: 781198

Strand: Direct

Name: nudG [C]

Synonym: azo0728

Alternate gene names: 119897019

Gene position: 780242-781198 (Clockwise)

Preceding gene: 119897018

Following gene: 119897031

Centisome position: 17.83

GC content: 70.64

Gene sequence:

>957_bases
ATGGCTGAGGTGGGCGCCCGCAAGATCGTCAATGTCGCGGCCGGGGTCATCCTGGAGCGCGGACGGGTGTTGCTCGGGCA
GCGCGCACCCGACACCTTCTATCCCGGCTACTGGGAATTCCCCGGAGGCAAGGTCGAACCTGGCGAATCCGCGGCAGATG
CGCTCAAGCGCGAGCTGGCCGAGGAGCTAGGCATCGTGGTGCCGCACGTGCGGCCCTGGCTGACCCGCGAGCACGACTAC
GAACACGCTCACGTCCGCTTGCACTTCTTCGAGGTTCCGGCGTGGTCGGGAGCGCCGGTGGCGCACGTGCATGCGGCGCT
GCGCTGGGCCGAGCCGGAGCTGATTGCGACCGCGTGCGCGCCGATGCTGCCCGCCAACGGCCCGATCCTGAAGGCGCTGC
AACTGCCGCGCCGGATGGGTATCACGCAGGCCGCCGAACGGGGCGTGGCGCGTCAGCTGGACGAGCTTGAGCAGGCCCTG
GGCGCGGGCCTGCGCCTGGTGCAGGTGCGCGAAGCGGCGCTGCCTCGCCGGCAGCAGATCGAATTCGCACAGGAAGTGGT
GCGCCGCGTAGCCGCGGCCGGTGGAATCGTGGTCATCAATGGCGACCTCGATCTTGCCCGTGCAGTGGGTGCGCCCGGGG
TGCACCTTCCGTCAGCGGCACTCCTTGATTGCACGGTCCGCCCCGCGTTCGAGTGGGTCGGAGCGTCTTGCCACTCGGAA
GAGGAGCTGCGGGCGGCGGCGGCCCTGGGGCTGGACTACGCCGTGCTCGGGCCGGTGCGGCCCACGGCATCCCATCCTGG
CCAGGCTGCGCTCGGCTGGGCGCGCTTTGGCGAGTTGGCAGGCACGCTGCCATTTCCGGTCTTTGCGCTCGGTGGTCTCG
GCTGGGGCGACATGGATTGCGCCCGCGACCATGGGGCGCATGGTGTTGCGGCGATCCGCGGGGCGTGGGGCGCTTAG

Upstream 100 bases:

>100_bases
GCGGCGGCACGCCAGGAAGCGCTGCAGTGGGCGCTGATGCGTGGCGCACGCTCTGGGCGGGTTGCGTGGCAGTTCGCGCG
GGACTACGCGGGCCGGGAGG

Downstream 100 bases:

>100_bases
CGTCCGGAGCCGGTTTCGGCCGCGTCAGTGTCGTCGGGGGGCGAGGTCGGAACCTTGTATTCCTCGCTCGCCCATGCACC
GAGGTCGATCTGGCGGCAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MAEVGARKIVNVAAGVILERGRVLLGQRAPDTFYPGYWEFPGGKVEPGESAADALKRELAEELGIVVPHVRPWLTREHDY
EHAHVRLHFFEVPAWSGAPVAHVHAALRWAEPELIATACAPMLPANGPILKALQLPRRMGITQAAERGVARQLDELEQAL
GAGLRLVQVREAALPRRQQIEFAQEVVRRVAAAGGIVVINGDLDLARAVGAPGVHLPSAALLDCTVRPAFEWVGASCHSE
EELRAAAALGLDYAVLGPVRPTASHPGQAALGWARFGELAGTLPFPVFALGGLGWGDMDCARDHGAHGVAAIRGAWGA

Sequences:

>Translated_318_residues
MAEVGARKIVNVAAGVILERGRVLLGQRAPDTFYPGYWEFPGGKVEPGESAADALKRELAEELGIVVPHVRPWLTREHDY
EHAHVRLHFFEVPAWSGAPVAHVHAALRWAEPELIATACAPMLPANGPILKALQLPRRMGITQAAERGVARQLDELEQAL
GAGLRLVQVREAALPRRQQIEFAQEVVRRVAAAGGIVVINGDLDLARAVGAPGVHLPSAALLDCTVRPAFEWVGASCHSE
EELRAAAALGLDYAVLGPVRPTASHPGQAALGWARFGELAGTLPFPVFALGGLGWGDMDCARDHGAHGVAAIRGAWGA
>Mature_317_residues
AEVGARKIVNVAAGVILERGRVLLGQRAPDTFYPGYWEFPGGKVEPGESAADALKRELAEELGIVVPHVRPWLTREHDYE
HAHVRLHFFEVPAWSGAPVAHVHAALRWAEPELIATACAPMLPANGPILKALQLPRRMGITQAAERGVARQLDELEQALG
AGLRLVQVREAALPRRQQIEFAQEVVRRVAAAGGIVVINGDLDLARAVGAPGVHLPSAALLDCTVRPAFEWVGASCHSEE
ELRAAAALGLDYAVLGPVRPTASHPGQAALGWARFGELAGTLPFPVFALGGLGWGDMDCARDHGAHGVAAIRGAWGA

Specific function: Specific For Pyrimidine Substrates. Acts On 5-Methyl- Dctp, Ctp And Dctp In Decreasing Order. [C]

COG id: COG0352

COG function: function code H; Thiamine monophosphate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TMP-PPase family [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=126, Percent_Identity=39.6825396825397, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786288, Length=128, Percent_Identity=32.03125, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022998
- InterPro:   IPR003733 [H]

Pfam domain/function: PF02581 TMP-TENI [H]

EC number: 3.6.1.-; 2.5.1.3

Molecular weight: Translated: 33828; Mature: 33697

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00893 NUDIX ; PS00304 SASP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVGARKIVNVAAGVILERGRVLLGQRAPDTFYPGYWEFPGGKVEPGESAADALKRELA
CCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHH
EELGIVVPHVRPWLTREHDYEHAHVRLHFFEVPAWSGAPVAHVHAALRWAEPELIATACA
HHHCEECCCCCHHHCCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHH
PMLPANGPILKALQLPRRMGITQAAERGVARQLDELEQALGAGLRLVQVREAALPRRQQI
HCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHCCHHHHH
EFAQEVVRRVAAAGGIVVINGDLDLARAVGAPGVHLPSAALLDCTVRPAFEWVGASCHSE
HHHHHHHHHHHHCCCEEEEECCHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHCCCCCCH
EELRAAAALGLDYAVLGPVRPTASHPGQAALGWARFGELAGTLPFPVFALGGLGWGDMDC
HHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHH
ARDHGAHGVAAIRGAWGA
HHHCCCCCHHHHCCCCCC
>Mature Secondary Structure 
AEVGARKIVNVAAGVILERGRVLLGQRAPDTFYPGYWEFPGGKVEPGESAADALKRELA
CCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHH
EELGIVVPHVRPWLTREHDYEHAHVRLHFFEVPAWSGAPVAHVHAALRWAEPELIATACA
HHHCEECCCCCHHHCCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHH
PMLPANGPILKALQLPRRMGITQAAERGVARQLDELEQALGAGLRLVQVREAALPRRQQI
HCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHCCHHHHH
EFAQEVVRRVAAAGGIVVINGDLDLARAVGAPGVHLPSAALLDCTVRPAFEWVGASCHSE
HHHHHHHHHHHHCCCEEEEECCHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHCCCCCCH
EELRAAAALGLDYAVLGPVRPTASHPGQAALGWARFGELAGTLPFPVFALGGLGWGDMDC
HHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHH
ARDHGAHGVAAIRGAWGA
HHHCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]