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The map label for this gene is ruvC

Identifier: 119896862

GI number: 119896862

Start: 601871

End: 602422

Strand: Reverse

Name: ruvC

Synonym: azo0571

Alternate gene names: 119896862

Gene position: 602422-601871 (Counterclockwise)

Preceding gene: 119896863

Following gene: 119896861

Centisome position: 13.77

GC content: 70.65

Gene sequence:

>552_bases
ATGAGCAGCGCCGGCCGCATCGTCGCCACCCGCATCCTCGGGCTGGATCCGGGGCTGCGCATCACCGGCTTCGGCGTCAT
CGACACCCTCGGCAGCCAGCTGCGCTACGTCGCCAGCGGTTGCATCAAGACCCGCGACGGTGAACTCCCCGGCCGCCTAA
AGACCCTGCTCGACGGCGTGCGCGAAGTCATCGCCACCTACCAGCCGGACGCGGTGGCGGTGGAAAAGGTCTTCGTCAAC
GTCAACCCGCAATCGACCCTGCTGCTGGGCCAGGCGCGTGGCGCGGTGATCTGCGGCGCGGTCTCGTGCGACCTCCCGGT
AGCCGAATACACCGCGCTGCAGGTCAAGCAGTCGGTGGTCGGCTACGGCAAGGCCGCCAAGGAGCAGGTGCAGCACATGG
TGCAGCGCCTGCTGGCGCTCGACGCCAGCCCCGGTCCCGACGCCGCCGACGCGCTCGCATGCGCGATCTGCCACGCTCAT
GGGGGCCAGGGCCTGGGCGGGCAGGCCGGTATCGGCGGCCGCCGGCGCGCAGGGCGCATCCTGAGCTTGTAA

Upstream 100 bases:

>100_bases
GTCCTCGGCCAGGACAACGGAATGCTGATGGTCTGCGTCAGCGGCACCGCGGTGATCACGGCTTGAGCGCACGCCGCAGC
GGTCGCCCGGCGGCGGTGCG

Downstream 100 bases:

>100_bases
CCGACTTGCAAGAAAATTCAGCGAAACGCTTGCGCAACGGCTGAACGCCGGCTAATATGCGCGCTTCTCGACGCCGGGCA
ACACAGCGCAGCGAGAAACG

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MSSAGRIVATRILGLDPGLRITGFGVIDTLGSQLRYVASGCIKTRDGELPGRLKTLLDGVREVIATYQPDAVAVEKVFVN
VNPQSTLLLGQARGAVICGAVSCDLPVAEYTALQVKQSVVGYGKAAKEQVQHMVQRLLALDASPGPDAADALACAICHAH
GGQGLGGQAGIGGRRRAGRILSL

Sequences:

>Translated_183_residues
MSSAGRIVATRILGLDPGLRITGFGVIDTLGSQLRYVASGCIKTRDGELPGRLKTLLDGVREVIATYQPDAVAVEKVFVN
VNPQSTLLLGQARGAVICGAVSCDLPVAEYTALQVKQSVVGYGKAAKEQVQHMVQRLLALDASPGPDAADALACAICHAH
GGQGLGGQAGIGGRRRAGRILSL
>Mature_182_residues
SSAGRIVATRILGLDPGLRITGFGVIDTLGSQLRYVASGCIKTRDGELPGRLKTLLDGVREVIATYQPDAVAVEKVFVNV
NPQSTLLLGQARGAVICGAVSCDLPVAEYTALQVKQSVVGYGKAAKEQVQHMVQRLLALDASPGPDAADALACAICHAHG
GQGLGGQAGIGGRRRAGRILSL

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=153, Percent_Identity=57.516339869281, Blast_Score=156, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_AZOSB (A1K2Y3)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_932075.1
- ProteinModelPortal:   A1K2Y3
- SMR:   A1K2Y3
- STRING:   A1K2Y3
- GeneID:   4610009
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo0571
- eggNOG:   COG0817
- HOGENOM:   HBG437552
- OMA:   RTGWGVI
- PhylomeDB:   A1K2Y3
- ProtClustDB:   PRK00039
- BioCyc:   ASP62928:AZO0571-MONOMER
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 18899; Mature: 18768

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAGRIVATRILGLDPGLRITGFGVIDTLGSQLRYVASGCIKTRDGELPGRLKTLLDGV
CCCCCHHHHHHEECCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
REVIATYQPDAVAVEKVFVNVNPQSTLLLGQARGAVICGAVSCDLPVAEYTALQVKQSVV
HHHHHHCCCCCEEEEEEEEECCCCCEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHH
GYGKAAKEQVQHMVQRLLALDASPGPDAADALACAICHAHGGQGLGGQAGIGGRRRAGRI
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
LSL
CCC
>Mature Secondary Structure 
SSAGRIVATRILGLDPGLRITGFGVIDTLGSQLRYVASGCIKTRDGELPGRLKTLLDGV
CCCCHHHHHHEECCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
REVIATYQPDAVAVEKVFVNVNPQSTLLLGQARGAVICGAVSCDLPVAEYTALQVKQSVV
HHHHHHCCCCCEEEEEEEEECCCCCEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHH
GYGKAAKEQVQHMVQRLLALDASPGPDAADALACAICHAHGGQGLGGQAGIGGRRRAGRI
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
LSL
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA