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The map label for this gene is nahD [H]

Identifier: 119896686

GI number: 119896686

Start: 421777

End: 422394

Strand: Direct

Name: nahD [H]

Synonym: azo0395

Alternate gene names: 119896686

Gene position: 421777-422394 (Clockwise)

Preceding gene: 119896685

Following gene: 119896687

Centisome position: 9.64

GC content: 68.77

Gene sequence:

>618_bases
GTGACACCGCCGAAGACGATCGACTTCTGGTTCGATTTCTCCTCGCCCTACGGCTATTTCATGAGCGAGAAGATCGACGC
CGTCGCGCGCCGCCACGGCCGTGACGTGCGCTGGCGGCCCTTCCTGCTCGGTGTGGTCTACAAGGAGATCGGGTCGCGGC
CGCTCACCGAGGTGCCGCTGAAAGGCGAGTACACCCGGCGCGACCTGCTACGGACCGCGCGTTTCCTCGATCTGCCGTTC
GCGCTGCCGTCGCCGTTTCCGGTGGCAACCCAGCATGCGGCGCGCTGCTTCTACTGGCTGCAGGCGGACGATGAGGCGCT
CGCGCGGCGTTTCGCCCACGCGGCCTACCGCGCCTATTTCGTCGAGGGGCGTGATATCTCGCAGCAGGTGGAGGTGGTGT
CGATCGCCGCCGCGCTGGAGGTGGATGGCGCGGCGCTGAGCGCTGCCTTGGGCGACGCGCCGGTGAAGGAGCGTCTGCGC
GCCGCGTCGGCGGAGGCGATCGCCGCCGGCGTTTTCGGTTCGCCCTATGTCATCATCGACGGCGAACCGTTCTGGGGCGT
GGACCGTCTGCCGCAGATCGAAGCCTGGCTCGCGGAACGTTCCGCCGCGGGCCGCTGA

Upstream 100 bases:

>100_bases
TCCCGCTTTCCCTCCCCCGTTCGACCGCCGCGCCCGCGGGATCTTTTTTACATCGCCTTGCGCTGCGCCCGGGCGTGGTG
CTGGCCTTGGAGGCCGCCGC

Downstream 100 bases:

>100_bases
CCAAAGCGCTGTCAGCGCCAGATAACGATATTCGCCTCCCGACCCCCGACATGAGCCCCGCCTCCCCTTGCATCAACGTC
TGTCGCATGGATGCCGCCAC

Product: 2-hydroxychromene-2-carboxylate isomerase family protein

Products: NA

Alternate protein names: HCCA isomerase [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MTPPKTIDFWFDFSSPYGYFMSEKIDAVARRHGRDVRWRPFLLGVVYKEIGSRPLTEVPLKGEYTRRDLLRTARFLDLPF
ALPSPFPVATQHAARCFYWLQADDEALARRFAHAAYRAYFVEGRDISQQVEVVSIAAALEVDGAALSAALGDAPVKERLR
AASAEAIAAGVFGSPYVIIDGEPFWGVDRLPQIEAWLAERSAAGR

Sequences:

>Translated_205_residues
MTPPKTIDFWFDFSSPYGYFMSEKIDAVARRHGRDVRWRPFLLGVVYKEIGSRPLTEVPLKGEYTRRDLLRTARFLDLPF
ALPSPFPVATQHAARCFYWLQADDEALARRFAHAAYRAYFVEGRDISQQVEVVSIAAALEVDGAALSAALGDAPVKERLR
AASAEAIAAGVFGSPYVIIDGEPFWGVDRLPQIEAWLAERSAAGR
>Mature_204_residues
TPPKTIDFWFDFSSPYGYFMSEKIDAVARRHGRDVRWRPFLLGVVYKEIGSRPLTEVPLKGEYTRRDLLRTARFLDLPFA
LPSPFPVATQHAARCFYWLQADDEALARRFAHAAYRAYFVEGRDISQQVEVVSIAAALEVDGAALSAALGDAPVKERLRA
ASAEAIAAGVFGSPYVIIDGEPFWGVDRLPQIEAWLAERSAAGR

Specific function: Catalyzes the isomerization of 2-hydroxychromene-2- carboxylate (HCCA) to trans-O-hydroxybenzylidenepyruvate (THBPA). The reaction is reversible [H]

COG id: COG3917

COG function: function code Q; 2-hydroxychromene-2-carboxylate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI17539520, Length=209, Percent_Identity=31.1004784688995, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538137, Length=205, Percent_Identity=27.3170731707317, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR014440
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA [H]

EC number: NA

Molecular weight: Translated: 22894; Mature: 22763

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPKTIDFWFDFSSPYGYFMSEKIDAVARRHGRDVRWRPFLLGVVYKEIGSRPLTEVPL
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
KGEYTRRDLLRTARFLDLPFALPSPFPVATQHAARCFYWLQADDEALARRFAHAAYRAYF
CCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHE
VEGRDISQQVEVVSIAAALEVDGAALSAALGDAPVKERLRAASAEAIAAGVFGSPYVIID
ECCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEC
GEPFWGVDRLPQIEAWLAERSAAGR
CCCCCCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
TPPKTIDFWFDFSSPYGYFMSEKIDAVARRHGRDVRWRPFLLGVVYKEIGSRPLTEVPL
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
KGEYTRRDLLRTARFLDLPFALPSPFPVATQHAARCFYWLQADDEALARRFAHAAYRAYF
CCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHE
VEGRDISQQVEVVSIAAALEVDGAALSAALGDAPVKERLRAASAEAIAAGVFGSPYVIID
ECCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEC
GEPFWGVDRLPQIEAWLAERSAAGR
CCCCCCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002605; 1447127 [H]