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The map label for this gene is fadfX [H]

Identifier: 119896685

GI number: 119896685

Start: 420508

End: 421641

Strand: Direct

Name: fadfX [H]

Synonym: azo0394

Alternate gene names: 119896685

Gene position: 420508-421641 (Clockwise)

Preceding gene: 119896684

Following gene: 119896686

Centisome position: 9.61

GC content: 67.99

Gene sequence:

>1134_bases
ATGATTCTGACCTCCGAACAGGAACTTATCCGCGACTCCATCCGCGCCTTCGCGCAGGAGCGCCTTGCCCCCTTCGCCGC
CGAATGGGACCGCAACCACACCTTTCCGCGCCAGGCGCTGAAGGAACTCGCCGAACTCGGCGCGCTCGGCATGGTGGTGC
CGGAAGAATGGGGCGGCGCCGGCATGGACTACATGAGCCTGGTGCTGGCGCTCGAAGAGATCGCCGCCGGCGATGGCGCC
ACCTCCACCATCGTCAGCGTGCAGAACTCGCTCGCCTGCGGCATCCCGGCCAAGTACGGCACCGATGCGCAGAAGGAGCG
CTGGCTCAAGCCGCTGGCGCGCGGCGACATGCTGGGCTGCTTCTGCCTGACCGAGCCGCACGTCGGCTCCGACGCCTCGG
CGCTGCGGACCACCGCGGTGCGCGACGGTGACGACTGGGTGCTCAACGGCGTCAAGCAGTTCATCACCACCGGGCGCGAG
GCCGATGTCGCCATCGTGTTCGCGGTCACCGACAAGGCGGCCGGCAAGAAGGGGATTTCCTGCTTCATCGTGCCGACCGC
GACGCCCGGCTACATCGTCGCCCGCATCGAGGAGAAGATGGGCCAGAAGGCGTCCGACACCGCGCAGATCCTGTTCGAGA
ACTGCCGCGTGCCGGCCGACGCGCTGCTCGGGGCCGAGGGCGAAGGCTACAAGATCGCGCTCTCCAACCTCGAAGCCGGC
CGCATCGGCATCGCCTCGCAGTGCCTGGGCATGGCGCGCGCCGCGCTCGAGGCCGCGGTGAAATACGCGCAGGAGCGCGA
GACCTTCGGCAAGCCCATCTTCGAACACCAGGCGGTGAACTTCCGCCTCGCCGACATGGCGACGCAACTGGAGGCCGCGC
GCCAGCTGGTGTGGCACGCCGCCAGCCTGAAGGACGCCGGCCGGCCCTGCCTGAAGGAGGCGTCGATGGCCAAGCTGTTC
GCCTCCGAGATGGCGGAGAAGGTGTGCTCGGATGCGATCCAGATCCACGGCGGTTACGGCTACGTCAGCGACTTTCCGGT
CGAGCGCATCTACCGCGACGTGCGGGTGTGCCAGATCTACGAGGGTGCTTCCGATATCCAGAAGCTGGTGATCGGGCGCG
CGCTGGCGCAGTAG

Upstream 100 bases:

>100_bases
ACAGTCCTCGCACGCTCCACAAGCACCCGACACGTCCGGCTCGACGCGGGGGCTTGCTGAACCCTTGTTATGGAAGGCTT
TGCCTTCCCACGGAAATCCC

Downstream 100 bases:

>100_bases
TCTTTCGCGATCCTGCGGACGGGTCGCGGCGGTTTTCCCGCTTTCCCTCCCCCGTTCGACCGCCGCGCCCGCGGGATCTT
TTTTACATCGCCTTGCGCTG

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MILTSEQELIRDSIRAFAQERLAPFAAEWDRNHTFPRQALKELAELGALGMVVPEEWGGAGMDYMSLVLALEEIAAGDGA
TSTIVSVQNSLACGIPAKYGTDAQKERWLKPLARGDMLGCFCLTEPHVGSDASALRTTAVRDGDDWVLNGVKQFITTGRE
ADVAIVFAVTDKAAGKKGISCFIVPTATPGYIVARIEEKMGQKASDTAQILFENCRVPADALLGAEGEGYKIALSNLEAG
RIGIASQCLGMARAALEAAVKYAQERETFGKPIFEHQAVNFRLADMATQLEAARQLVWHAASLKDAGRPCLKEASMAKLF
ASEMAEKVCSDAIQIHGGYGYVSDFPVERIYRDVRVCQIYEGASDIQKLVIGRALAQ

Sequences:

>Translated_377_residues
MILTSEQELIRDSIRAFAQERLAPFAAEWDRNHTFPRQALKELAELGALGMVVPEEWGGAGMDYMSLVLALEEIAAGDGA
TSTIVSVQNSLACGIPAKYGTDAQKERWLKPLARGDMLGCFCLTEPHVGSDASALRTTAVRDGDDWVLNGVKQFITTGRE
ADVAIVFAVTDKAAGKKGISCFIVPTATPGYIVARIEEKMGQKASDTAQILFENCRVPADALLGAEGEGYKIALSNLEAG
RIGIASQCLGMARAALEAAVKYAQERETFGKPIFEHQAVNFRLADMATQLEAARQLVWHAASLKDAGRPCLKEASMAKLF
ASEMAEKVCSDAIQIHGGYGYVSDFPVERIYRDVRVCQIYEGASDIQKLVIGRALAQ
>Mature_377_residues
MILTSEQELIRDSIRAFAQERLAPFAAEWDRNHTFPRQALKELAELGALGMVVPEEWGGAGMDYMSLVLALEEIAAGDGA
TSTIVSVQNSLACGIPAKYGTDAQKERWLKPLARGDMLGCFCLTEPHVGSDASALRTTAVRDGDDWVLNGVKQFITTGRE
ADVAIVFAVTDKAAGKKGISCFIVPTATPGYIVARIEEKMGQKASDTAQILFENCRVPADALLGAEGEGYKIALSNLEAG
RIGIASQCLGMARAALEAAVKYAQERETFGKPIFEHQAVNFRLADMATQLEAARQLVWHAASLKDAGRPCLKEASMAKLF
ASEMAEKVCSDAIQIHGGYGYVSDFPVERIYRDVRVCQIYEGASDIQKLVIGRALAQ

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=369, Percent_Identity=50.9485094850949, Blast_Score=387, Evalue=1e-107,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=41.5549597855228, Blast_Score=310, Evalue=1e-84,
Organism=Homo sapiens, GI226958412, Length=377, Percent_Identity=37.6657824933687, Blast_Score=276, Evalue=2e-74,
Organism=Homo sapiens, GI7656849, Length=378, Percent_Identity=37.8306878306878, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI4557231, Length=374, Percent_Identity=38.2352941176471, Blast_Score=266, Evalue=2e-71,
Organism=Homo sapiens, GI187960098, Length=374, Percent_Identity=38.2352941176471, Blast_Score=266, Evalue=2e-71,
Organism=Homo sapiens, GI226958414, Length=368, Percent_Identity=35.5978260869565, Blast_Score=251, Evalue=8e-67,
Organism=Homo sapiens, GI4501857, Length=376, Percent_Identity=34.5744680851064, Blast_Score=241, Evalue=6e-64,
Organism=Homo sapiens, GI21361497, Length=350, Percent_Identity=34.8571428571429, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI76496475, Length=337, Percent_Identity=37.3887240356083, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI4557235, Length=337, Percent_Identity=37.3887240356083, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI4503943, Length=377, Percent_Identity=32.3607427055703, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI7669494, Length=362, Percent_Identity=31.767955801105, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI38505218, Length=282, Percent_Identity=32.6241134751773, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI211971008, Length=284, Percent_Identity=30.6338028169014, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI48976061, Length=284, Percent_Identity=30.6338028169014, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI218563752, Length=261, Percent_Identity=26.4367816091954, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI156104864, Length=334, Percent_Identity=24.5508982035928, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI156104866, Length=334, Percent_Identity=24.5508982035928, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI87081958, Length=379, Percent_Identity=32.9815303430079, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1786223, Length=374, Percent_Identity=29.4117647058824, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI87081702, Length=362, Percent_Identity=27.3480662983425, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI87082384, Length=275, Percent_Identity=30.9090909090909, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17506239, Length=374, Percent_Identity=38.7700534759358, Blast_Score=291, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=39.622641509434, Blast_Score=286, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI17534899, Length=378, Percent_Identity=38.0952380952381, Blast_Score=267, Evalue=8e-72,
Organism=Caenorhabditis elegans, GI17538396, Length=377, Percent_Identity=35.0132625994695, Blast_Score=267, Evalue=9e-72,
Organism=Caenorhabditis elegans, GI17569725, Length=377, Percent_Identity=37.9310344827586, Blast_Score=261, Evalue=6e-70,
Organism=Caenorhabditis elegans, GI17570075, Length=376, Percent_Identity=37.5, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI71990804, Length=293, Percent_Identity=41.296928327645, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17533517, Length=375, Percent_Identity=34.6666666666667, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI71985184, Length=355, Percent_Identity=38.5915492957746, Blast_Score=233, Evalue=9e-62,
Organism=Caenorhabditis elegans, GI17551932, Length=378, Percent_Identity=32.5396825396825, Blast_Score=207, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI17505929, Length=377, Percent_Identity=30.5039787798408, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI32563615, Length=254, Percent_Identity=39.3700787401575, Blast_Score=191, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI71982178, Length=268, Percent_Identity=34.7014925373134, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17534353, Length=376, Percent_Identity=31.1170212765957, Blast_Score=181, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI71985192, Length=284, Percent_Identity=36.6197183098592, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=35.2697095435685, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17562446, Length=285, Percent_Identity=30.1754385964912, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17531913, Length=179, Percent_Identity=35.195530726257, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI86563383, Length=276, Percent_Identity=28.6231884057971, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI86563381, Length=276, Percent_Identity=28.6231884057971, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356377, Length=369, Percent_Identity=48.5094850948509, Blast_Score=364, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24646207, Length=373, Percent_Identity=44.7721179624665, Blast_Score=332, Evalue=4e-91,
Organism=Drosophila melanogaster, GI24666513, Length=376, Percent_Identity=38.031914893617, Blast_Score=291, Evalue=4e-79,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=39.9470899470899, Blast_Score=269, Evalue=2e-72,
Organism=Drosophila melanogaster, GI21355753, Length=379, Percent_Identity=36.1477572559367, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI281363737, Length=387, Percent_Identity=34.1085271317829, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI19920834, Length=380, Percent_Identity=33.4210526315789, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI281365206, Length=278, Percent_Identity=25.1798561151079, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24585193, Length=278, Percent_Identity=25.1798561151079, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24585195, Length=278, Percent_Identity=25.1798561151079, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24585191, Length=278, Percent_Identity=25.1798561151079, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 40740; Mature: 40740

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILTSEQELIRDSIRAFAQERLAPFAAEWDRNHTFPRQALKELAELGALGMVVPEEWGGA
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
GMDYMSLVLALEEIAAGDGATSTIVSVQNSLACGIPAKYGTDAQKERWLKPLARGDMLGC
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEE
FCLTEPHVGSDASALRTTAVRDGDDWVLNGVKQFITTGREADVAIVFAVTDKAAGKKGIS
EEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCE
CFIVPTATPGYIVARIEEKMGQKASDTAQILFENCRVPADALLGAEGEGYKIALSNLEAG
EEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCCC
RIGIASQCLGMARAALEAAVKYAQERETFGKPIFEHQAVNFRLADMATQLEAARQLVWHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ASLKDAGRPCLKEASMAKLFASEMAEKVCSDAIQIHGGYGYVSDFPVERIYRDVRVCQIY
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHH
EGASDIQKLVIGRALAQ
CCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MILTSEQELIRDSIRAFAQERLAPFAAEWDRNHTFPRQALKELAELGALGMVVPEEWGGA
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
GMDYMSLVLALEEIAAGDGATSTIVSVQNSLACGIPAKYGTDAQKERWLKPLARGDMLGC
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEE
FCLTEPHVGSDASALRTTAVRDGDDWVLNGVKQFITTGREADVAIVFAVTDKAAGKKGIS
EEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCE
CFIVPTATPGYIVARIEEKMGQKASDTAQILFENCRVPADALLGAEGEGYKIALSNLEAG
EEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCCC
RIGIASQCLGMARAALEAAVKYAQERETFGKPIFEHQAVNFRLADMATQLEAARQLVWHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ASLKDAGRPCLKEASMAKLFASEMAEKVCSDAIQIHGGYGYVSDFPVERIYRDVRVCQIY
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHH
EGASDIQKLVIGRALAQ
CCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]