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The map label for this gene is paaZ [H]

Identifier: 119896590

GI number: 119896590

Start: 322766

End: 324430

Strand: Reverse

Name: paaZ [H]

Synonym: azo0299

Alternate gene names: 119896590

Gene position: 324430-322766 (Counterclockwise)

Preceding gene: 119896608

Following gene: 119896589

Centisome position: 7.41

GC content: 67.93

Gene sequence:

>1665_bases
ATGACCCACCCGCTCTACGCCAAGCACCAGGCGACGCTCGAGGCCGCGCTGGCCGCCATCCACACCCGCGGCTACTGGAC
GCCGTATGCGGAAATGCCCAGTCCCAAGGTCTATGGCGAAACCGCCGCGGACGACGGCAAGCGCGCCTTCGAGGCCTGCC
TCGGCAAGGATTTCGAGCTGGATCAACCGGGCCGCAGCGGCTGGGCTGCGTCGGAACGTTCACCGTATGGCATCGCGCTC
GACGTGCGCTATCCGGTTTGCGAGCCGAGCGCGCTGATCGCCGCCGCCGAAGCCGCGATGCCCGGCTGGCGCAAGATCGG
CGCCGAAGGCCGGGTCGGCGTCTGCCTGGAAATCCTCGATCGCCTGAACAAGCGCAGCTTCGAGATCGCCCATGCGGTGA
TGATGACCACCGGCCAGGGCTGGATGATGGCTTTCCAGGCCGGCGGCCCGCATGCGCAGGACCGCGGCCTCGAAGCCGTC
GCCTACGCCTGGGACGCGATGCGCGGCGTGCCGGCCACCACCGTGTGGGAAAAGCCGCAGGGCAAGAACCCGCCGCTGAA
GATGCAGAAGCACTACGAGATCGTCGGCCGCGGCGTCGCGCTGGTGGTCGGCTGCGGCACCTTCCCGACCTGGAACACCT
ACCCCGGCCTGTTCGCCGCGCTTGCCACCGGCAACCCGGTGATCGTCAAGCCGCACAGCAACGCCATCCTGCCCGCGGCA
ATGACGGTGAAGATCGCCCGCGAGGTGCTGGCCGAGGCCGGCCTCGACCCCAGCGTCGTCAGCCTGGCGGTGGTCGAGAA
GCGCAGCGACACCCAGGCGCTCGCCACCCATCCGGCGGTGAAGTCGATCGATTTCACCGGCAGCAACGTCTTCGGCCAGT
GGCTGATCGACAACGCCAGACAGGCCCAGGTGTATGCCGAACTCGCCGGCGTGAACAACGTGGTGATCGAATCCACCGAC
AACTACAAGGCGATGCTGCGCAACCTCGCGTTCACGCTGTGCCTGTATTCCGGCCAGATGTGCACCACCACCCAGGCCAT
CCTCGTCCCGGCCGGCGGCATCGATACCGACCAGGGCCACAAGCGCTACGACGAAGTCGCCGCCGACCTCGGCGCCGCGA
TCGACAAGTTCCTGTCCGACCCGGCGGTCGCCACCGCGGTGCTGGGCGCAATCCAGTCCGATGCCACGCTCGCCCGCATC
AACGAAGCCGGCCAATACGGTGACATCGTGCTGGCCTCGAAGAAGATCGAGCACCCGGAATTCCCCCAGGCCGAAGTGCG
CACCCCGGTGCTGCTTGCCTGCGACGCCGCCGCCGAGAAGAGCTATATGGAAGAGCGCTTCGGCCCGATCGCCTTCGTGG
TCAAGGTTGCCGACGGCGCCGCCGCGGTGGCACTGTCCGAGCGCATCGTCCGCGAGCACGGCGCCCTGACAGTGGGCCTG
TACTCGACCAAGGCGGAAGTCATCGACGCGATGACCGAGGCCACGCTGCGCGCCGGCGTCGCGCTGTCGATCAACCTCAC
CGGCGGCGTGTTCGTGAACCAGTCGGCGGCCTTCTCCGACTACCACGGCGTCGGCATGAACCCGGCCGCCAACGCCAGCT
ACTCGGATGCCGCCTTCGTCGCCAACCGCTTCCGCGTCGTACAGCGGCGCTATCACGTCGAGTAA

Upstream 100 bases:

>100_bases
TTTTCACGCCGCGGCGACGCCCGCGACTGTCGCGGCTAGAGGCGCGGAGCGCGTGCCGCGAAGGCTGCGGCCGCACCGCC
TACAACGGAGGAGACAACCG

Downstream 100 bases:

>100_bases
GCTGGAACGCCCCGACCACGTTTGAGGCGGCAGACGGTTTTCTCCCTCCCCTTCAAGGGGAGGGCTGGGGTGGGGATGGG
GTTGGGCGCAGCGCTCACTT

Product: dehydrogenase

Products: NA

Alternate protein names: Succinylglutamic semialdehyde dehydrogenase; SGSD [H]

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MTHPLYAKHQATLEAALAAIHTRGYWTPYAEMPSPKVYGETAADDGKRAFEACLGKDFELDQPGRSGWAASERSPYGIAL
DVRYPVCEPSALIAAAEAAMPGWRKIGAEGRVGVCLEILDRLNKRSFEIAHAVMMTTGQGWMMAFQAGGPHAQDRGLEAV
AYAWDAMRGVPATTVWEKPQGKNPPLKMQKHYEIVGRGVALVVGCGTFPTWNTYPGLFAALATGNPVIVKPHSNAILPAA
MTVKIAREVLAEAGLDPSVVSLAVVEKRSDTQALATHPAVKSIDFTGSNVFGQWLIDNARQAQVYAELAGVNNVVIESTD
NYKAMLRNLAFTLCLYSGQMCTTTQAILVPAGGIDTDQGHKRYDEVAADLGAAIDKFLSDPAVATAVLGAIQSDATLARI
NEAGQYGDIVLASKKIEHPEFPQAEVRTPVLLACDAAAEKSYMEERFGPIAFVVKVADGAAAVALSERIVREHGALTVGL
YSTKAEVIDAMTEATLRAGVALSINLTGGVFVNQSAAFSDYHGVGMNPAANASYSDAAFVANRFRVVQRRYHVE

Sequences:

>Translated_554_residues
MTHPLYAKHQATLEAALAAIHTRGYWTPYAEMPSPKVYGETAADDGKRAFEACLGKDFELDQPGRSGWAASERSPYGIAL
DVRYPVCEPSALIAAAEAAMPGWRKIGAEGRVGVCLEILDRLNKRSFEIAHAVMMTTGQGWMMAFQAGGPHAQDRGLEAV
AYAWDAMRGVPATTVWEKPQGKNPPLKMQKHYEIVGRGVALVVGCGTFPTWNTYPGLFAALATGNPVIVKPHSNAILPAA
MTVKIAREVLAEAGLDPSVVSLAVVEKRSDTQALATHPAVKSIDFTGSNVFGQWLIDNARQAQVYAELAGVNNVVIESTD
NYKAMLRNLAFTLCLYSGQMCTTTQAILVPAGGIDTDQGHKRYDEVAADLGAAIDKFLSDPAVATAVLGAIQSDATLARI
NEAGQYGDIVLASKKIEHPEFPQAEVRTPVLLACDAAAEKSYMEERFGPIAFVVKVADGAAAVALSERIVREHGALTVGL
YSTKAEVIDAMTEATLRAGVALSINLTGGVFVNQSAAFSDYHGVGMNPAANASYSDAAFVANRFRVVQRRYHVE
>Mature_553_residues
THPLYAKHQATLEAALAAIHTRGYWTPYAEMPSPKVYGETAADDGKRAFEACLGKDFELDQPGRSGWAASERSPYGIALD
VRYPVCEPSALIAAAEAAMPGWRKIGAEGRVGVCLEILDRLNKRSFEIAHAVMMTTGQGWMMAFQAGGPHAQDRGLEAVA
YAWDAMRGVPATTVWEKPQGKNPPLKMQKHYEIVGRGVALVVGCGTFPTWNTYPGLFAALATGNPVIVKPHSNAILPAAM
TVKIAREVLAEAGLDPSVVSLAVVEKRSDTQALATHPAVKSIDFTGSNVFGQWLIDNARQAQVYAELAGVNNVVIESTDN
YKAMLRNLAFTLCLYSGQMCTTTQAILVPAGGIDTDQGHKRYDEVAADLGAAIDKFLSDPAVATAVLGAIQSDATLARIN
EAGQYGDIVLASKKIEHPEFPQAEVRTPVLLACDAAAEKSYMEERFGPIAFVVKVADGAAAVALSERIVREHGALTVGLY
STKAEVIDAMTEATLRAGVALSINLTGGVFVNQSAAFSDYHGVGMNPAANASYSDAAFVANRFRVVQRRYHVE

Specific function: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family. AstD subfamily [H]

Homologues:

Organism=Caenorhabditis elegans, GI115534176, Length=303, Percent_Identity=25.0825082508251, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321828, Length=326, Percent_Identity=24.2331288343558, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320917, Length=278, Percent_Identity=29.136690647482, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR017649 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.71 [H]

Molecular weight: Translated: 59213; Mature: 59082

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPLYAKHQATLEAALAAIHTRGYWTPYAEMPSPKVYGETAADDGKRAFEACLGKDFEL
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
DQPGRSGWAASERSPYGIALDVRYPVCEPSALIAAAEAAMPGWRKIGAEGRVGVCLEILD
CCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHH
RLNKRSFEIAHAVMMTTGQGWMMAFQAGGPHAQDRGLEAVAYAWDAMRGVPATTVWEKPQ
HHCCCHHHHHHEEEEECCCCEEEEEECCCCCCHHCCCHHHHHHHHHHCCCCCCEEECCCC
GKNPPLKMQKHYEIVGRGVALVVGCGTFPTWNTYPGLFAALATGNPVIVKPHSNAILPAA
CCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCHH
MTVKIAREVLAEAGLDPSVVSLAVVEKRSDTQALATHPAVKSIDFTGSNVFGQWLIDNAR
HHHHHHHHHHHHCCCCHHHEEEEEECCCCCCHHHHCCCCCCEEECCCCCCCHHHHHCCCH
QAQVYAELAGVNNVVIESTDNYKAMLRNLAFTLCLYSGQMCTTTQAILVPAGGIDTDQGH
HHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCH
KRYDEVAADLGAAIDKFLSDPAVATAVLGAIQSDATLARINEAGQYGDIVLASKKIEHPE
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEEECCCCCCC
FPQAEVRTPVLLACDAAAEKSYMEERFGPIAFVVKVADGAAAVALSERIVREHGALTVGL
CCHHHCCCCEEEEECCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEE
YSTKAEVIDAMTEATLRAGVALSINLTGGVFVNQSAAFSDYHGVGMNPAANASYSDAAFV
ECHHHHHHHHHHHHHHHCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHH
ANRFRVVQRRYHVE
HHHHHHHHHHHCCC
>Mature Secondary Structure 
THPLYAKHQATLEAALAAIHTRGYWTPYAEMPSPKVYGETAADDGKRAFEACLGKDFEL
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
DQPGRSGWAASERSPYGIALDVRYPVCEPSALIAAAEAAMPGWRKIGAEGRVGVCLEILD
CCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHH
RLNKRSFEIAHAVMMTTGQGWMMAFQAGGPHAQDRGLEAVAYAWDAMRGVPATTVWEKPQ
HHCCCHHHHHHEEEEECCCCEEEEEECCCCCCHHCCCHHHHHHHHHHCCCCCCEEECCCC
GKNPPLKMQKHYEIVGRGVALVVGCGTFPTWNTYPGLFAALATGNPVIVKPHSNAILPAA
CCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCHH
MTVKIAREVLAEAGLDPSVVSLAVVEKRSDTQALATHPAVKSIDFTGSNVFGQWLIDNAR
HHHHHHHHHHHHCCCCHHHEEEEEECCCCCCHHHHCCCCCCEEECCCCCCCHHHHHCCCH
QAQVYAELAGVNNVVIESTDNYKAMLRNLAFTLCLYSGQMCTTTQAILVPAGGIDTDQGH
HHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCH
KRYDEVAADLGAAIDKFLSDPAVATAVLGAIQSDATLARINEAGQYGDIVLASKKIEHPE
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEEECCCCCCC
FPQAEVRTPVLLACDAAAEKSYMEERFGPIAFVVKVADGAAAVALSERIVREHGALTVGL
CCHHHCCCCEEEEECCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEE
YSTKAEVIDAMTEATLRAGVALSINLTGGVFVNQSAAFSDYHGVGMNPAANASYSDAAFV
ECHHHHHHHHHHHHHHHCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHH
ANRFRVVQRRYHVE
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA