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The map label for this gene is exbB1 [H]

Identifier: 119896523

GI number: 119896523

Start: 259217

End: 260059

Strand: Direct

Name: exbB1 [H]

Synonym: azo0232

Alternate gene names: 119896523

Gene position: 259217-260059 (Clockwise)

Preceding gene: 119896522

Following gene: 119896524

Centisome position: 5.92

GC content: 68.09

Gene sequence:

>843_bases
ATGAAACTTCGGCGCTTCTTCTCGTCCCTTTCCCTGGCCTTCGCCATCGCCTGCGGCGCCGTGTCGGCCCCGGCCTTCGC
GCAGTCCGATCCCGCCACCACCGCCAGCGCCGACAGCGCGTCCGCCGTGGCCGGCACCATCGACGCTGCGCCGACGGCCA
AGCCGGCCGCCGGGGCTGCAGCCAAGGTGGAGAACCCCTACGGCCTCGAAGCGCTGTGGGCCGGCAGCGACGCGGTTGCC
AAGGTGGTGCTGGTGCTGATGATCATCATGAGCGCGGGCAGCTGGTACATCATCATCGTCAAGCTGATCGAGCAGACCCG
CATGTATCGCCAGGCCAAGGCGGTGGAGGGCGTGTGGAAGTCGGCCACGATCAAGCACGGCGCCGAGAACCTGGAGAACG
GCAGCCCGTTCCGCTTCATCGCCGAAGCCGGCCTGGAAGCCACCAACCGCCACGACAGCCTGCTCGAGCACGTCGACCTC
AATGACTGGGTCACGCTCAGCATTCACCGCGCCATCGAGAAGGTGCAGAGCCGCATGCAGAACGGCCTGGCCTTCCTCGC
CACGGTCGGTTCCACCGCGCCTTTCGTCGGCCTCTTCGGCACCGTGTGGGGCATCTATCACGCGCTGACCGCGATCGGCA
TCGCCGGCCAGGCCTCGATCGACAAGGTTGCCGGCCCGGTGGGCGAGGCGCTGATCATGACCGCCATCGGCCTCGCCGTC
GCGGTGCCGGCGGTGCTCGGCTACAACTGGCTGGTCCGCCGCAACAAGGGCGTGATGGACCAGGTCCGCGGCTTCGGCAA
CGAACTGCACACCGTCATCCTGTCGTCGGCCAAGCGCGCCTGA

Upstream 100 bases:

>100_bases
GCTACAAGCGCACCAGCAAGCGCGCCTGGGTCCGCTACTTCTGACTTTCCCTCTTCATCCGGTCTTCACCGCAATCCGTC
CAGTACCACAGGAGTCGTAA

Downstream 100 bases:

>100_bases
GCGCCGCGCCGGAAGGAGCGCCACCATGGCCATGAACGTAGGCTCGGCGGACGAAGACGATGGCGTCATGTCGGCGATCA
ACACCACGCCGCTGGTCGAC

Product: putative biopolymer transport protein ExbB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MKLRRFFSSLSLAFAIACGAVSAPAFAQSDPATTASADSASAVAGTIDAAPTAKPAAGAAAKVENPYGLEALWAGSDAVA
KVVLVLMIIMSAGSWYIIIVKLIEQTRMYRQAKAVEGVWKSATIKHGAENLENGSPFRFIAEAGLEATNRHDSLLEHVDL
NDWVTLSIHRAIEKVQSRMQNGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGEALIMTAIGLAV
AVPAVLGYNWLVRRNKGVMDQVRGFGNELHTVILSSAKRA

Sequences:

>Translated_280_residues
MKLRRFFSSLSLAFAIACGAVSAPAFAQSDPATTASADSASAVAGTIDAAPTAKPAAGAAAKVENPYGLEALWAGSDAVA
KVVLVLMIIMSAGSWYIIIVKLIEQTRMYRQAKAVEGVWKSATIKHGAENLENGSPFRFIAEAGLEATNRHDSLLEHVDL
NDWVTLSIHRAIEKVQSRMQNGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGEALIMTAIGLAV
AVPAVLGYNWLVRRNKGVMDQVRGFGNELHTVILSSAKRA
>Mature_280_residues
MKLRRFFSSLSLAFAIACGAVSAPAFAQSDPATTASADSASAVAGTIDAAPTAKPAAGAAAKVENPYGLEALWAGSDAVA
KVVLVLMIIMSAGSWYIIIVKLIEQTRMYRQAKAVEGVWKSATIKHGAENLENGSPFRFIAEAGLEATNRHDSLLEHVDL
NDWVTLSIHRAIEKVQSRMQNGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGEALIMTAIGLAV
AVPAVLGYNWLVRRNKGVMDQVRGFGNELHTVILSSAKRA

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=224, Percent_Identity=30.3571428571429, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1789381, Length=190, Percent_Identity=30.5263157894737, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 29416; Mature: 29416

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRRFFSSLSLAFAIACGAVSAPAFAQSDPATTASADSASAVAGTIDAAPTAKPAAGAA
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCH
AKVENPYGLEALWAGSDAVAKVVLVLMIIMSAGSWYIIIVKLIEQTRMYRQAKAVEGVWK
HCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SATIKHGAENLENGSPFRFIAEAGLEATNRHDSLLEHVDLNDWVTLSIHRAIEKVQSRMQ
HHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHH
NGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGEALIMTAIGLAV
CCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AVPAVLGYNWLVRRNKGVMDQVRGFGNELHTVILSSAKRA
HHHHHHCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLRRFFSSLSLAFAIACGAVSAPAFAQSDPATTASADSASAVAGTIDAAPTAKPAAGAA
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCH
AKVENPYGLEALWAGSDAVAKVVLVLMIIMSAGSWYIIIVKLIEQTRMYRQAKAVEGVWK
HCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SATIKHGAENLENGSPFRFIAEAGLEATNRHDSLLEHVDLNDWVTLSIHRAIEKVQSRMQ
HHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHH
NGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGEALIMTAIGLAV
CCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AVPAVLGYNWLVRRNKGVMDQVRGFGNELHTVILSSAKRA
HHHHHHCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]