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The map label for this gene is rodA [H]

Identifier: 119896470

GI number: 119896470

Start: 194683

End: 195819

Strand: Direct

Name: rodA [H]

Synonym: azo0178

Alternate gene names: 119896470

Gene position: 194683-195819 (Clockwise)

Preceding gene: 119896469

Following gene: 119896471

Centisome position: 4.45

GC content: 65.7

Gene sequence:

>1137_bases
ATGAGCGATCACCGCTTCAATCCGCTGCTGTTGCTGCGCGCGGTGCTGCGTCCGATCGACCCGGTGCTGATGCTGGTGCT
GATGATGTTGCTCGGCTACGCCTTTGTGCTGATGGCGAGCGCGTCGCCAGACCGGCTGGACTCGCAACTGGTCAACACCA
CCGTGGCGCTGCTGGCGATGTGGGTGGCGGCCTGGCTGCCCAGCCAGCGCTTGCTGAGTTTCGCGCTGCCCTTGTATGCG
CTGGGCGTGGTACTGCTGGTCGCGGTCGAACTGTTCGGCGAGGTCTCGAAGGGCGCGCAGCGCTGGCTGCACGTCGGCGT
GACCCGCATCCAGCCCTCGGAGCTGATGAAGATCGCGATGCCGCTGATGCTGGCGTGGTACTTCCAGCAGCGCGAGGCCA
AGATCGGCCTGCGCGAGTTCATCGTCGCCGGCCTGCTGCTGGTGGTGCCGGTAGGCCTGATCCTGATCCAGCCCGATCTG
GGCACCAGCCTGCTGGTGACCGCCGCGGGCTTCTACGTGATTTTCTTCGCCGGCCTGTCGTGGAAGCTGATCGTCCCGGT
CGGCCTCGTCGGCATCATCGGCATCGGCTCCATCGTCGCCTTCGGCGACACCCTGTGCCAGCCCGACGTCGATTGGTTCG
GCCTGCGCGAATACCAGAAGCAGCGCGTATGCACCCTGCTCGATCCCACGCGCGACCCGCTGGGCAAGGGCTTCCACATC
ATCCAGTCCACGATCGCGATCGGCTCCGGCGGCGTGGTCGGCAAAGGCTGGATGGACGGCACCCAGACCCACCTCGCCTT
CCTGCCCGAGCGGCATACCGATTTCATCTTCGCGGTGCTCGCCGAGGAGTTCGGCCTGGTCGGCACGCTGGTGCTGCTCG
TCACCTATCTGGCTTTGCTTGCGCGCAGCTTCCAGATCGCCACGCAGGCGCCGACGCTGGCGACCAAGCTGCTGGGCGGG
GCGATGGCGATGATCTTCTTCACCTATGCGTTCGTGAACATGGGCATGGTCAGCGGAATCCTGCCGGTGGTGGGTGTGCC
CTTGCCATTCATCAGCTATGGTGGGACGGCACTGGTCACCTTGTGCCTCGGGGTGGGTATCCTGATGGGCATCCGCCGTG
GCCGTCCCGCGTCCTGA

Upstream 100 bases:

>100_bases
CGGCGGCCCCGATCGCACGCCAGGTGATCGACTACCACCTGCTCGGCAAGCGGCCCAACCAGCCCGCCGGCGAGGATGCG
GATGCACCGGAGAGCACCGA

Downstream 100 bases:

>100_bases
TCTGCCTGCCGTCATGATGATGAAGTCCGTCCCCGCCGCCTTCACCCTCCGTGCCCGCCCGCTGACGCTCGTGGTGGCGA
GCTGTTGCGCCGCCTGGTTG

Product: rod shape-determining protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MSDHRFNPLLLLRAVLRPIDPVLMLVLMMLLGYAFVLMASASPDRLDSQLVNTTVALLAMWVAAWLPSQRLLSFALPLYA
LGVVLLVAVELFGEVSKGAQRWLHVGVTRIQPSELMKIAMPLMLAWYFQQREAKIGLREFIVAGLLLVVPVGLILIQPDL
GTSLLVTAAGFYVIFFAGLSWKLIVPVGLVGIIGIGSIVAFGDTLCQPDVDWFGLREYQKQRVCTLLDPTRDPLGKGFHI
IQSTIAIGSGGVVGKGWMDGTQTHLAFLPERHTDFIFAVLAEEFGLVGTLVLLVTYLALLARSFQIATQAPTLATKLLGG
AMAMIFFTYAFVNMGMVSGILPVVGVPLPFISYGGTALVTLCLGVGILMGIRRGRPAS

Sequences:

>Translated_378_residues
MSDHRFNPLLLLRAVLRPIDPVLMLVLMMLLGYAFVLMASASPDRLDSQLVNTTVALLAMWVAAWLPSQRLLSFALPLYA
LGVVLLVAVELFGEVSKGAQRWLHVGVTRIQPSELMKIAMPLMLAWYFQQREAKIGLREFIVAGLLLVVPVGLILIQPDL
GTSLLVTAAGFYVIFFAGLSWKLIVPVGLVGIIGIGSIVAFGDTLCQPDVDWFGLREYQKQRVCTLLDPTRDPLGKGFHI
IQSTIAIGSGGVVGKGWMDGTQTHLAFLPERHTDFIFAVLAEEFGLVGTLVLLVTYLALLARSFQIATQAPTLATKLLGG
AMAMIFFTYAFVNMGMVSGILPVVGVPLPFISYGGTALVTLCLGVGILMGIRRGRPAS
>Mature_377_residues
SDHRFNPLLLLRAVLRPIDPVLMLVLMMLLGYAFVLMASASPDRLDSQLVNTTVALLAMWVAAWLPSQRLLSFALPLYAL
GVVLLVAVELFGEVSKGAQRWLHVGVTRIQPSELMKIAMPLMLAWYFQQREAKIGLREFIVAGLLLVVPVGLILIQPDLG
TSLLVTAAGFYVIFFAGLSWKLIVPVGLVGIIGIGSIVAFGDTLCQPDVDWFGLREYQKQRVCTLLDPTRDPLGKGFHII
QSTIAIGSGGVVGKGWMDGTQTHLAFLPERHTDFIFAVLAEEFGLVGTLVLLVTYLALLARSFQIATQAPTLATKLLGGA
MAMIFFTYAFVNMGMVSGILPVVGVPLPFISYGGTALVTLCLGVGILMGIRRGRPAS

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=360, Percent_Identity=47.7777777777778, Blast_Score=284, Evalue=5e-78,
Organism=Escherichia coli, GI1786277, Length=295, Percent_Identity=33.5593220338983, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40895; Mature: 40764

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDHRFNPLLLLRAVLRPIDPVLMLVLMMLLGYAFVLMASASPDRLDSQLVNTTVALLAM
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
WVAAWLPSQRLLSFALPLYALGVVLLVAVELFGEVSKGAQRWLHVGVTRIQPSELMKIAM
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
PLMLAWYFQQREAKIGLREFIVAGLLLVVPVGLILIQPDLGTSLLVTAAGFYVIFFAGLS
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCC
WKLIVPVGLVGIIGIGSIVAFGDTLCQPDVDWFGLREYQKQRVCTLLDPTRDPLGKGFHI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHCHHHH
IQSTIAIGSGGVVGKGWMDGTQTHLAFLPERHTDFIFAVLAEEFGLVGTLVLLVTYLALL
HHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARSFQIATQAPTLATKLLGGAMAMIFFTYAFVNMGMVSGILPVVGVPLPFISYGGTALVT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHH
LCLGVGILMGIRRGRPAS
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SDHRFNPLLLLRAVLRPIDPVLMLVLMMLLGYAFVLMASASPDRLDSQLVNTTVALLAM
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
WVAAWLPSQRLLSFALPLYALGVVLLVAVELFGEVSKGAQRWLHVGVTRIQPSELMKIAM
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
PLMLAWYFQQREAKIGLREFIVAGLLLVVPVGLILIQPDLGTSLLVTAAGFYVIFFAGLS
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCC
WKLIVPVGLVGIIGIGSIVAFGDTLCQPDVDWFGLREYQKQRVCTLLDPTRDPLGKGFHI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHCHHHH
IQSTIAIGSGGVVGKGWMDGTQTHLAFLPERHTDFIFAVLAEEFGLVGTLVLLVTYLALL
HHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARSFQIATQAPTLATKLLGGAMAMIFFTYAFVNMGMVSGILPVVGVPLPFISYGGTALVT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHH
LCLGVGILMGIRRGRPAS
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]