Click here to switch to the map view.

The map label for this gene is hsdM [C]

Identifier: 119896296

GI number: 119896296

Start: 5505

End: 7346

Strand: Direct

Name: hsdM [C]

Synonym: azo0004

Alternate gene names: 119896296

Gene position: 5505-7346 (Clockwise)

Preceding gene: 119896295

Following gene: 119896297

Centisome position: 0.13

GC content: 63.68

Gene sequence:

>1842_bases
ATGAACCACCAAGCCCTCTCATCCTTCATCTGGTCCGTCGCCGACCTCCTGCGCGGCGACTACAAGCAATCCGAATACGG
CAAGGTCATCCTGCCCTTCACCGTGCTGCGCCGCCTCGACTGCGTGCTCGAAGCCACCAAGCCCTCCGTGCTGGCCGAGC
TGGAAGCCAAAACCAAAGCCGGGCTAAATCCCGATCCCTTCCTGCTGCGCAAATCCGGCCAGAGCTTCTACAACACCGCC
CCGCTGGACCTCGTCAAACTGCTCGGCGACCAGGACCACATCCGCCAGAACCTCTACACCTACGTGCAGGCCTTCTCGCC
AGCGGCGCGCGACATCTTCGAGCGTTTCGACTTTTTCACCCAGGTCGAGCGCCTGGCGAAGGCCAACCTGCTCTACCTCG
TCACCGAAAAGTTCGCCAACATCGACCTCCACCCCGAGGCCGTCGACAACACCAGCATGGGCCTGGTGTTCGAAGAGCTC
ATCCGCAAGTTCGCCGAAATCTCCAACGAAACCGCCGGGGAGCACTTCACCCCGCGCGAAGTCATCCGCCTGATGGTGAA
CCTGCTCTTCATCGAGGATGACGACGTGCTCACCCCCGGCAATGCCGTCGTGCGCACCATCTACGACCCCACCGCCGGCA
CCGGTGGCATGCTCTCGGTGGCGGGCGAGTTCCTGCTGGAACACAACCCGCAGGCGCGGCTCACCATGTTCGGCCAGGAA
CTCAACGACGAGTCCTACGCCATCTGCAAGGCCGACATGCTCATCAAGGGCCAGGACGTCGCCAACATCGTCGCCGGCAA
CACCCTCTCGGACGATGGCCACGGCGCCCGCAAGTTCGACTACATGCTCTCCAATCCCCCCTTCGGCGTGGAATGGAAGA
AGGTCGAAAAGGCCGTGCGCCAGGAACACGAACAGAAAGGCTTCGACGGCCGCTTCGGCCCCGGCCTGCCGCGCGTGTCC
GACGGCTCCATGCTCTTCCTGATGCACCTGCTGTCCAAGATGCGCCCGGCGCAGGACGGCGGCAGCCGCTTCGGCATCGT
CCTCAACGGCTCGCCGCTGTTCACCGGCGGCGCCGGCAGCGGCGAATCCGAGATCCGCCGCTATGTGCTGGAGAACGATC
TGGTCGAAGCCATCGTCGGCCTGCCCACCGACATGTTTTACAACACCGGCATCGCCACCTATGTCTGGATCATTTCCAAC
CGCAAGAAAGCCGACCGCAAGGGCCAGGTCCAACTCATCGACGCCAGCAGCTTCTGGCAGAAGATGCGGAAGAGCCTGGG
TTCCAAGCGCAAGGAGATGAGCGACGCGCACATCGCCACCGTCACCCGCCTGTTCGGCAGCTTCACCGAGGCCGAGTACA
TCACCGTGTTCGACGCCGCCGGCCAGCAGCTCGGCGAGCCGCAGCTCGTCACCAATACGGATACCCCGCCCAAGGCGCCG
GAAGGCGGCCGCCTCAAGCGCGTGCCCATCGCCCGCATCTTCAGGAATCAAGACTTCGGCTACACCACCATCACCGTCGA
GCGCCCGCTCAAGGACGAAGCCGGCAAACCGGTGCTGGGCAGCAAGGGCGCGCGACGCGGCAAACCGCAGGCGGACAGCG
CCCTGCGCGACACCGAGAACGTACCGCTCGGCGAGGACATCTCCGCCTACTTCAAACGCGAAGTGCTGCCGCACGCGCCG
GACGCCTGGATAGACGAAACCAAGAGCAAGGTCGGCTACGAGATTCCCTTCAACCGCCACTTCTACGTTTTCGAGCCGCC
GCGCAGCCTGCACGCCATCGACGAAGAGCTGAAGACCGTCTCGGCCAACATCATGAAGATGCTGGAGGGTTTGGCGGAAT
GA

Upstream 100 bases:

>100_bases
CGAATACCCAGTAGAAATTCAACGGCCACGCATAGTGGCCGTTCCTTTTTGGGATATCGTTTTCCGGTTTGGCGCGACAC
GAAGCCTCAGAAGAAAGACC

Downstream 100 bases:

>100_bases
GCGCTTTTTCCCTTCAGGGAGGAAGCTTGTCTTTCAAGGCTGTCTTTATCACACGCGAAAAACGACAAGCGCTTTTCTTT
TTTAAAAATCAGTAGCTTGC

Product: site-specific DNA-methyltransferase

Products: NA

Alternate protein names: M.MjaXP [H]

Number of amino acids: Translated: 613; Mature: 613

Protein sequence:

>613_residues
MNHQALSSFIWSVADLLRGDYKQSEYGKVILPFTVLRRLDCVLEATKPSVLAELEAKTKAGLNPDPFLLRKSGQSFYNTA
PLDLVKLLGDQDHIRQNLYTYVQAFSPAARDIFERFDFFTQVERLAKANLLYLVTEKFANIDLHPEAVDNTSMGLVFEEL
IRKFAEISNETAGEHFTPREVIRLMVNLLFIEDDDVLTPGNAVVRTIYDPTAGTGGMLSVAGEFLLEHNPQARLTMFGQE
LNDESYAICKADMLIKGQDVANIVAGNTLSDDGHGARKFDYMLSNPPFGVEWKKVEKAVRQEHEQKGFDGRFGPGLPRVS
DGSMLFLMHLLSKMRPAQDGGSRFGIVLNGSPLFTGGAGSGESEIRRYVLENDLVEAIVGLPTDMFYNTGIATYVWIISN
RKKADRKGQVQLIDASSFWQKMRKSLGSKRKEMSDAHIATVTRLFGSFTEAEYITVFDAAGQQLGEPQLVTNTDTPPKAP
EGGRLKRVPIARIFRNQDFGYTTITVERPLKDEAGKPVLGSKGARRGKPQADSALRDTENVPLGEDISAYFKREVLPHAP
DAWIDETKSKVGYEIPFNRHFYVFEPPRSLHAIDEELKTVSANIMKMLEGLAE

Sequences:

>Translated_613_residues
MNHQALSSFIWSVADLLRGDYKQSEYGKVILPFTVLRRLDCVLEATKPSVLAELEAKTKAGLNPDPFLLRKSGQSFYNTA
PLDLVKLLGDQDHIRQNLYTYVQAFSPAARDIFERFDFFTQVERLAKANLLYLVTEKFANIDLHPEAVDNTSMGLVFEEL
IRKFAEISNETAGEHFTPREVIRLMVNLLFIEDDDVLTPGNAVVRTIYDPTAGTGGMLSVAGEFLLEHNPQARLTMFGQE
LNDESYAICKADMLIKGQDVANIVAGNTLSDDGHGARKFDYMLSNPPFGVEWKKVEKAVRQEHEQKGFDGRFGPGLPRVS
DGSMLFLMHLLSKMRPAQDGGSRFGIVLNGSPLFTGGAGSGESEIRRYVLENDLVEAIVGLPTDMFYNTGIATYVWIISN
RKKADRKGQVQLIDASSFWQKMRKSLGSKRKEMSDAHIATVTRLFGSFTEAEYITVFDAAGQQLGEPQLVTNTDTPPKAP
EGGRLKRVPIARIFRNQDFGYTTITVERPLKDEAGKPVLGSKGARRGKPQADSALRDTENVPLGEDISAYFKREVLPHAP
DAWIDETKSKVGYEIPFNRHFYVFEPPRSLHAIDEELKTVSANIMKMLEGLAE
>Mature_613_residues
MNHQALSSFIWSVADLLRGDYKQSEYGKVILPFTVLRRLDCVLEATKPSVLAELEAKTKAGLNPDPFLLRKSGQSFYNTA
PLDLVKLLGDQDHIRQNLYTYVQAFSPAARDIFERFDFFTQVERLAKANLLYLVTEKFANIDLHPEAVDNTSMGLVFEEL
IRKFAEISNETAGEHFTPREVIRLMVNLLFIEDDDVLTPGNAVVRTIYDPTAGTGGMLSVAGEFLLEHNPQARLTMFGQE
LNDESYAICKADMLIKGQDVANIVAGNTLSDDGHGARKFDYMLSNPPFGVEWKKVEKAVRQEHEQKGFDGRFGPGLPRVS
DGSMLFLMHLLSKMRPAQDGGSRFGIVLNGSPLFTGGAGSGESEIRRYVLENDLVEAIVGLPTDMFYNTGIATYVWIISN
RKKADRKGQVQLIDASSFWQKMRKSLGSKRKEMSDAHIATVTRLFGSFTEAEYITVFDAAGQQLGEPQLVTNTDTPPKAP
EGGRLKRVPIARIFRNQDFGYTTITVERPLKDEAGKPVLGSKGARRGKPQADSALRDTENVPLGEDISAYFKREVLPHAP
DAWIDETKSKVGYEIPFNRHFYVFEPPRSLHAIDEELKTVSANIMKMLEGLAE

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 68429; Mature: 68429

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHQALSSFIWSVADLLRGDYKQSEYGKVILPFTVLRRLDCVLEATKPSVLAELEAKTKA
CCHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
GLNPDPFLLRKSGQSFYNTAPLDLVKLLGDQDHIRQNLYTYVQAFSPAARDIFERFDFFT
CCCCCCEEEECCCCCHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
QVERLAKANLLYLVTEKFANIDLHPEAVDNTSMGLVFEELIRKFAEISNETAGEHFTPRE
HHHHHHHCCEEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
VIRLMVNLLFIEDDDVLTPGNAVVRTIYDPTAGTGGMLSVAGEFLLEHNPQARLTMFGQE
HHHHHHHHHEECCCCEECCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEEECHH
LNDESYAICKADMLIKGQDVANIVAGNTLSDDGHGARKFDYMLSNPPFGVEWKKVEKAVR
CCCCCEEEEEECEEECCCCHHHHHCCCCCCCCCCCCCEEHHEECCCCCCCCHHHHHHHHH
QEHEQKGFDGRFGPGLPRVSDGSMLFLMHLLSKMRPAQDGGSRFGIVLNGSPLFTGGAGS
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCEEEECCCCC
GESEIRRYVLENDLVEAIVGLPTDMFYNTGIATYVWIISNRKKADRKGQVQLIDASSFWQ
CHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEEECCCCCCCCCCCEEEEEHHHHHH
KMRKSLGSKRKEMSDAHIATVTRLFGSFTEAEYITVFDAAGQQLGEPQLVTNTDTPPKAP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCEEECCCCCCCCC
EGGRLKRVPIARIFRNQDFGYTTITVERPLKDEAGKPVLGSKGARRGKPQADSALRDTEN
CCCCEECCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCC
VPLGEDISAYFKREVLPHAPDAWIDETKSKVGYEIPFNRHFYVFEPPRSLHAIDEELKTV
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCEECCCCCEEEEECCCHHHHHHHHHHHHH
SANIMKMLEGLAE
HHHHHHHHHHHCC
>Mature Secondary Structure
MNHQALSSFIWSVADLLRGDYKQSEYGKVILPFTVLRRLDCVLEATKPSVLAELEAKTKA
CCHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
GLNPDPFLLRKSGQSFYNTAPLDLVKLLGDQDHIRQNLYTYVQAFSPAARDIFERFDFFT
CCCCCCEEEECCCCCHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
QVERLAKANLLYLVTEKFANIDLHPEAVDNTSMGLVFEELIRKFAEISNETAGEHFTPRE
HHHHHHHCCEEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
VIRLMVNLLFIEDDDVLTPGNAVVRTIYDPTAGTGGMLSVAGEFLLEHNPQARLTMFGQE
HHHHHHHHHEECCCCEECCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEEECHH
LNDESYAICKADMLIKGQDVANIVAGNTLSDDGHGARKFDYMLSNPPFGVEWKKVEKAVR
CCCCCEEEEEECEEECCCCHHHHHCCCCCCCCCCCCCEEHHEECCCCCCCCHHHHHHHHH
QEHEQKGFDGRFGPGLPRVSDGSMLFLMHLLSKMRPAQDGGSRFGIVLNGSPLFTGGAGS
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCEEEECCCCC
GESEIRRYVLENDLVEAIVGLPTDMFYNTGIATYVWIISNRKKADRKGQVQLIDASSFWQ
CHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEEECCCCCCCCCCCEEEEEHHHHHH
KMRKSLGSKRKEMSDAHIATVTRLFGSFTEAEYITVFDAAGQQLGEPQLVTNTDTPPKAP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCEEECCCCCCCCC
EGGRLKRVPIARIFRNQDFGYTTITVERPLKDEAGKPVLGSKGARRGKPQADSALRDTEN
CCCCEECCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCC
VPLGEDISAYFKREVLPHAPDAWIDETKSKVGYEIPFNRHFYVFEPPRSLHAIDEELKTV
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCEECCCCCEEEEECCCHHHHHHHHHHHHH
SANIMKMLEGLAE
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]