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The map label for this gene is trxB [H]

Identifier: 119871514

GI number: 119871514

Start: 5733672

End: 5734673

Strand: Direct

Name: trxB [H]

Synonym: Mkms_5491

Alternate gene names: 119871514

Gene position: 5733672-5734673 (Clockwise)

Preceding gene: 119871513

Following gene: 119871515

Centisome position: 99.94

GC content: 68.26

Gene sequence:

>1002_bases
GTGCCGGTGCGAAACGGCAGAAAGGCTCACATGACCAGCTCATCGACGGTTCACGATGTGATCATCATCGGCTCCGGCCC
GGCCGGATACACGGCCGCCGTGTACGCCGCGCGCGCACAGCTCAAGCCGCTCGTATTCGAGGGCAGCCAGTTCGGCGGCG
CGCTCATGACCACGACCGAGGTGGAGAACTACCCCGGCTTCCGCAACGGCATCACCGGACCCGAACTGATGGACGAGATG
CGCGAGCAGGCGCTGCGCTTCGGCGCCGACCTGCGGATGGAGGACGTCGACGAGGTCTCCCTCGACGGCCCCGTCAAGAC
GGTCACCGTGGGCGACGAGACCCATCGGGCCCGGGCGGTCATCCTCGCGATGGGTGCCGCCGCACGCCACCTCGGCGTCC
CCGGCGAGGACGCGCTGCTCGGCATGGGCGTGAGCACCTGCGCGACCTGCGACGGCTTCTTCTTCCGCGATCAGGACATC
GCGGTCATCGGCGGCGGCGACTCGGCGATGGAGGAGGCGACGTTCCTCACCCGCTTCGCGCGCAGCGTGACGGTGATCCA
CCGCCGCGAGGAGTTCCGCGCCTCGCGCATCATGCTCGACCGCGCCCGCGCCAACGAGAAGATCACGTTCATGACCAACA
CCGCGGTCACCGAGATCGAGGGCGATCCCAAGGTGACCGGAATCCGCTTGCGCGACACCGTGACCGGTGAGGAGTCGAAG
CTCGCGGTGACCGGTGTGTTCGTCGCGATCGGGCACGTGCCGCGCTCGGACATCGTGCGTGGTCAGGTCGACGTCGACGA
GGACGGCTACGTCCTGGTCGAGGGTCGCACCACCAACACCTCCGTCGAAGGTGTCTTTGCCGCAGGCGATCTCGTGGACC
GCACCTACCGGCAGGCGATCACCGCCGCGGGCAGCGGTTGTTCGGCCGCCATCGACGCCGAGCGCTGGCTGGCCGAAATC
GGCGTCGCACCAAGCGATCAAGAGATCTCGGCCCCGATCTGA

Upstream 100 bases:

>100_bases
CGCGCCGTGCGTCACGCGGGTGGCGGGACACCGGTCGACCGGCCGTAGCGTGACCCTCCAGGCAGTCGGGAACACCCGGA
CCTAGGCTGGTGTTGTACCC

Downstream 100 bases:

>100_bases
GACATCTGACACACCCCTATCCCGAGGAGCACACATGGCCGACAGCGCCACCGTCACCGTCACCGACGACTCGTTCTCCG
AGGACGTGCTGACCAGCAGC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MPVRNGRKAHMTSSSTVHDVIIIGSGPAGYTAAVYAARAQLKPLVFEGSQFGGALMTTTEVENYPGFRNGITGPELMDEM
REQALRFGADLRMEDVDEVSLDGPVKTVTVGDETHRARAVILAMGAAARHLGVPGEDALLGMGVSTCATCDGFFFRDQDI
AVIGGGDSAMEEATFLTRFARSVTVIHRREEFRASRIMLDRARANEKITFMTNTAVTEIEGDPKVTGIRLRDTVTGEESK
LAVTGVFVAIGHVPRSDIVRGQVDVDEDGYVLVEGRTTNTSVEGVFAAGDLVDRTYRQAITAAGSGCSAAIDAERWLAEI
GVAPSDQEISAPI

Sequences:

>Translated_333_residues
MPVRNGRKAHMTSSSTVHDVIIIGSGPAGYTAAVYAARAQLKPLVFEGSQFGGALMTTTEVENYPGFRNGITGPELMDEM
REQALRFGADLRMEDVDEVSLDGPVKTVTVGDETHRARAVILAMGAAARHLGVPGEDALLGMGVSTCATCDGFFFRDQDI
AVIGGGDSAMEEATFLTRFARSVTVIHRREEFRASRIMLDRARANEKITFMTNTAVTEIEGDPKVTGIRLRDTVTGEESK
LAVTGVFVAIGHVPRSDIVRGQVDVDEDGYVLVEGRTTNTSVEGVFAAGDLVDRTYRQAITAAGSGCSAAIDAERWLAEI
GVAPSDQEISAPI
>Mature_332_residues
PVRNGRKAHMTSSSTVHDVIIIGSGPAGYTAAVYAARAQLKPLVFEGSQFGGALMTTTEVENYPGFRNGITGPELMDEMR
EQALRFGADLRMEDVDEVSLDGPVKTVTVGDETHRARAVILAMGAAARHLGVPGEDALLGMGVSTCATCDGFFFRDQDIA
VIGGGDSAMEEATFLTRFARSVTVIHRREEFRASRIMLDRARANEKITFMTNTAVTEIEGDPKVTGIRLRDTVTGEESKL
AVTGVFVAIGHVPRSDIVRGQVDVDEDGYVLVEGRTTNTSVEGVFAAGDLVDRTYRQAITAAGSGCSAAIDAERWLAEIG
VAPSDQEISAPI

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=307, Percent_Identity=49.8371335504886, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI87081763, Length=324, Percent_Identity=33.3333333333333, Blast_Score=160, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6320560, Length=317, Percent_Identity=49.5268138801262, Blast_Score=296, Evalue=3e-81,
Organism=Saccharomyces cerevisiae, GI6321898, Length=313, Percent_Identity=47.2843450479233, Blast_Score=282, Evalue=7e-77,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 35559; Mature: 35427

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVRNGRKAHMTSSSTVHDVIIIGSGPAGYTAAVYAARAQLKPLVFEGSQFGGALMTTTE
CCCCCCCEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEEEEE
VENYPGFRNGITGPELMDEMREQALRFGADLRMEDVDEVSLDGPVKTVTVGDETHRARAV
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHEEE
ILAMGAAARHLGVPGEDALLGMGVSTCATCDGFFFRDQDIAVIGGGDSAMEEATFLTRFA
EEEECHHHHHCCCCCCCCEEECCCHHHHCCCCEEEECCCEEEEECCCHHHHHHHHHHHHH
RSVTVIHRREEFRASRIMLDRARANEKITFMTNTAVTEIEGDPKVTGIRLRDTVTGEESK
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEECCCCCEEEEEEEEECCCCCCE
LAVTGVFVAIGHVPRSDIVRGQVDVDEDGYVLVEGRTTNTSVEGVFAAGDLVDRTYRQAI
EEEEEEEEEECCCCHHHHEECEEEECCCCEEEEECCCCCCCCCEEEECCHHHHHHHHHHH
TAAGSGCSAAIDAERWLAEIGVAPSDQEISAPI
HHCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PVRNGRKAHMTSSSTVHDVIIIGSGPAGYTAAVYAARAQLKPLVFEGSQFGGALMTTTE
CCCCCCEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEEEEE
VENYPGFRNGITGPELMDEMREQALRFGADLRMEDVDEVSLDGPVKTVTVGDETHRARAV
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHEEE
ILAMGAAARHLGVPGEDALLGMGVSTCATCDGFFFRDQDIAVIGGGDSAMEEATFLTRFA
EEEECHHHHHCCCCCCCCEEECCCHHHHCCCCEEEECCCEEEEECCCHHHHHHHHHHHHH
RSVTVIHRREEFRASRIMLDRARANEKITFMTNTAVTEIEGDPKVTGIRLRDTVTGEESK
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEECCCCCEEEEEEEEECCCCCCE
LAVTGVFVAIGHVPRSDIVRGQVDVDEDGYVLVEGRTTNTSVEGVFAAGDLVDRTYRQAI
EEEEEEEEEECCCCHHHHEECEEEECCCCEEEEECCCCCCCCCEEEECCHHHHHHHHHHH
TAAGSGCSAAIDAERWLAEIGVAPSDQEISAPI
HHCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9795994 [H]