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The map label for this gene is bcd [H]

Identifier: 119871388

GI number: 119871388

Start: 5599730

End: 5600887

Strand: Direct

Name: bcd [H]

Synonym: Mkms_5364

Alternate gene names: 119871388

Gene position: 5599730-5600887 (Clockwise)

Preceding gene: 119871383

Following gene: 119871389

Centisome position: 97.6

GC content: 72.11

Gene sequence:

>1158_bases
GTGATTTACACGCCACGGCCCGGCGCGGAAGCTGGCAGCGACGACAGGGAAGGCGGTTCGCCCATGACGATCGACGTCGC
CGAACGGGAAGCGCTGCAGGAGGCGGTCCGGGATCTGCTCCGCAGCCGGTGCACCGAGCAGGATGTCCGGCAGGTGCTGA
CCGGTGACGACGGGTTCGACCGCGACCTGTGGCGCCGGCTGGCCGAACAGGGTGTCACCGGCATCGTGATCGGCAGCGAG
TACGGCGGCGTGGGTCTGGGCGCGGTCGAGCTCGAGGCGGTGGCCGAGGAAACCGGGGCCGCGCTGCTCCCGTCGCCGTT
CATCTCCAGCGCGGTGCTCACCGCCGCCCTGGTCCAGGCCGCCGGCTCCGAGGACGACAAGCAGCGGCTGCTGCCCGGCC
TGGCCGACGGCACCGCGATCGGGACGGTCGCGGTCACCGGGCGGGCCGGCACCTGGACCGCCGAGGGCGTCGATGTGCGC
GCGGGTACCGACGGCACGTTGACCGGGAGCGCGCACTACGTGACCGACGGGCAGGTGGCCGACGTCCTGCTGGTGGTGGC
CAACGGCACCGACGGCGTGGGCGTCTACGAGGTCGACCCCGGCGCTTCCGGTTTCGAGCGCGTCGCGGCGACGGTCTTCG
ACCCGTCGGTGCGGCTGTCGACGTTCACCTTCACCGGCACCCCGGCGCGACGACTCGGCGCGGCCGGATGGGATGCCGTC
CAGCAGGCGCTGGACCTGGCGACGATCGCGCTGGCCGGCGAACAGTGCGGTGGGACCCGCCGCATCTTCGAGATCACCGT
CGAGTACCTCAAGACCCGCATCCAGTTCGGCCGTCCGATCGGCAGTTTCCAGGCGCTCAAGCACATGGCCGCCGATCTGC
TGCTCAAGGTCGAATCCTCGACATCGGCCGCGCAGAACGCCGCGGCCCAGCGGGACGCCGACCCGGACACCGCCGGCGGC
GCGATCGCCCTGGCCGGCTTCGCCTGTGCGGAGGCCTACCGCGACACCGCCGCGGCGGCCATCCAGATGCACGGCGGTAT
CGGCTTCACCTGGGAGCATCCGGCGCATCTGTACCTCCGCCGGGCCCGCACCGGGCTGCAGTTGTTCGGCGGCCCACGCC
TGCATCGCGAGCGTTACCTCCAGTCGAAAGGCGCCTGA

Upstream 100 bases:

>100_bases
CTCAGCGCACTCGGTGTGCACTCCCGCGTGGGTTATCGGTTCCAAGGTAGCGCAGCCACCCACACATGTCGCCATCGGAA
ACCCGAAGGTGTCGGAAGTC

Downstream 100 bases:

>100_bases
CCCATGACCGAGACGACTCCGAGCGCCGACGAGCTGCGCGCCGAGGTGCGTGCCTGGCTCGAGCACAACTGGAAGGGCCT
GCCGAAGTCGACCGATCCGT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MIYTPRPGAEAGSDDREGGSPMTIDVAEREALQEAVRDLLRSRCTEQDVRQVLTGDDGFDRDLWRRLAEQGVTGIVIGSE
YGGVGLGAVELEAVAEETGAALLPSPFISSAVLTAALVQAAGSEDDKQRLLPGLADGTAIGTVAVTGRAGTWTAEGVDVR
AGTDGTLTGSAHYVTDGQVADVLLVVANGTDGVGVYEVDPGASGFERVAATVFDPSVRLSTFTFTGTPARRLGAAGWDAV
QQALDLATIALAGEQCGGTRRIFEITVEYLKTRIQFGRPIGSFQALKHMAADLLLKVESSTSAAQNAAAQRDADPDTAGG
AIALAGFACAEAYRDTAAAAIQMHGGIGFTWEHPAHLYLRRARTGLQLFGGPRLHRERYLQSKGA

Sequences:

>Translated_385_residues
MIYTPRPGAEAGSDDREGGSPMTIDVAEREALQEAVRDLLRSRCTEQDVRQVLTGDDGFDRDLWRRLAEQGVTGIVIGSE
YGGVGLGAVELEAVAEETGAALLPSPFISSAVLTAALVQAAGSEDDKQRLLPGLADGTAIGTVAVTGRAGTWTAEGVDVR
AGTDGTLTGSAHYVTDGQVADVLLVVANGTDGVGVYEVDPGASGFERVAATVFDPSVRLSTFTFTGTPARRLGAAGWDAV
QQALDLATIALAGEQCGGTRRIFEITVEYLKTRIQFGRPIGSFQALKHMAADLLLKVESSTSAAQNAAAQRDADPDTAGG
AIALAGFACAEAYRDTAAAAIQMHGGIGFTWEHPAHLYLRRARTGLQLFGGPRLHRERYLQSKGA
>Mature_385_residues
MIYTPRPGAEAGSDDREGGSPMTIDVAEREALQEAVRDLLRSRCTEQDVRQVLTGDDGFDRDLWRRLAEQGVTGIVIGSE
YGGVGLGAVELEAVAEETGAALLPSPFISSAVLTAALVQAAGSEDDKQRLLPGLADGTAIGTVAVTGRAGTWTAEGVDVR
AGTDGTLTGSAHYVTDGQVADVLLVVANGTDGVGVYEVDPGASGFERVAATVFDPSVRLSTFTFTGTPARRLGAAGWDAV
QQALDLATIALAGEQCGGTRRIFEITVEYLKTRIQFGRPIGSFQALKHMAADLLLKVESSTSAAQNAAAQRDADPDTAGG
AIALAGFACAEAYRDTAAAAIQMHGGIGFTWEHPAHLYLRRARTGLQLFGGPRLHRERYLQSKGA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=350, Percent_Identity=22.8571428571429, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI226958412, Length=325, Percent_Identity=28, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI226958414, Length=348, Percent_Identity=27.0114942528736, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI4501859, Length=355, Percent_Identity=25.6338028169014, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI7656849, Length=334, Percent_Identity=22.7544910179641, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI4503943, Length=372, Percent_Identity=25, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI7669494, Length=336, Percent_Identity=24.4047619047619, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4557233, Length=322, Percent_Identity=24.223602484472, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17533517, Length=333, Percent_Identity=25.2252252252252, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=339, Percent_Identity=26.2536873156342, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17508101, Length=321, Percent_Identity=26.1682242990654, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17506239, Length=323, Percent_Identity=26.0061919504644, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17534899, Length=335, Percent_Identity=26.2686567164179, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71990804, Length=266, Percent_Identity=24.4360902255639, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569725, Length=343, Percent_Identity=24.7813411078717, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24666513, Length=370, Percent_Identity=25.1351351351351, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21355753, Length=326, Percent_Identity=25.1533742331288, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646207, Length=320, Percent_Identity=26.5625, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356377, Length=368, Percent_Identity=24.1847826086957, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920834, Length=289, Percent_Identity=25.9515570934256, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 40259; Mature: 40259

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYTPRPGAEAGSDDREGGSPMTIDVAEREALQEAVRDLLRSRCTEQDVRQVLTGDDGFD
CCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCC
RDLWRRLAEQGVTGIVIGSEYGGVGLGAVELEAVAEETGAALLPSPFISSAVLTAALVQA
HHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
AGSEDDKQRLLPGLADGTAIGTVAVTGRAGTWTAEGVDVRAGTDGTLTGSAHYVTDGQVA
CCCCCHHHHHCCCCCCCCEEEEEEEECCCCCEECCCEEEECCCCCEECCCEEEECCCCEE
DVLLVVANGTDGVGVYEVDPGASGFERVAATVFDPSVRLSTFTFTGTPARRLGAAGWDAV
EEEEEEECCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHCCCCHHHH
QQALDLATIALAGEQCGGTRRIFEITVEYLKTRIQFGRPIGSFQALKHMAADLLLKVESS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEECCC
TSAAQNAAAQRDADPDTAGGAIALAGFACAEAYRDTAAAAIQMHGGIGFTWEHPAHLYLR
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCHHHHHHH
RARTGLQLFGGPRLHRERYLQSKGA
HHHCCHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MIYTPRPGAEAGSDDREGGSPMTIDVAEREALQEAVRDLLRSRCTEQDVRQVLTGDDGFD
CCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCC
RDLWRRLAEQGVTGIVIGSEYGGVGLGAVELEAVAEETGAALLPSPFISSAVLTAALVQA
HHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
AGSEDDKQRLLPGLADGTAIGTVAVTGRAGTWTAEGVDVRAGTDGTLTGSAHYVTDGQVA
CCCCCHHHHHCCCCCCCCEEEEEEEECCCCCEECCCEEEECCCCCEECCCEEEECCCCEE
DVLLVVANGTDGVGVYEVDPGASGFERVAATVFDPSVRLSTFTFTGTPARRLGAAGWDAV
EEEEEEECCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHCCCCHHHH
QQALDLATIALAGEQCGGTRRIFEITVEYLKTRIQFGRPIGSFQALKHMAADLLLKVESS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEECCC
TSAAQNAAAQRDADPDTAGGAIALAGFACAEAYRDTAAAAIQMHGGIGFTWEHPAHLYLR
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCHHHHHHH
RARTGLQLFGGPRLHRERYLQSKGA
HHHCCHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]