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The map label for this gene is greA [H]

Identifier: 119871350

GI number: 119871350

Start: 5560535

End: 5560996

Strand: Direct

Name: greA [H]

Synonym: Mkms_5324

Alternate gene names: 119871350

Gene position: 5560535-5560996 (Clockwise)

Preceding gene: 119871349

Following gene: 119871351

Centisome position: 96.92

GC content: 69.26

Gene sequence:

>462_bases
ATGACGACAGCACAGCGTGTCTGGATGACCCCGGTCGCCTACCGGCGCCTACAGGACGAACTGACCGAACTCCGGACCCT
GATCGCCAACGAAGCGCCCGACGACGGCCAGGAGAACACCGTCGCGGTGCAGCGTGCCCGTCAGACCCGCATCCAGCAGA
TCCACGACCTGCTGCTCAACGCCGTGGTCGGCGAGGATCCGCCCGACGACGGTGTCGCCGAACCCGGCATGGTGCTGACG
GTGCGATTCGACCAGACCGGCGACGAGGAGACGTTCCTGCTCGGCGTCCGCGGAGCGGAGTACGGCGACCTCGAGGTGTA
CTCGGTGAGCTCCCCGCTCGGTGAGGCACTGATCGGCGCCCGGCCCGGTGATCGGCGCACCTATGAGGTGCCCAGCGGGG
CGTCCGTCCCGGTCACGCTGCTCAAGGCGGTGCCGTTCGGGATGCACCACCCGCGCGGCTGA

Upstream 100 bases:

>100_bases
CCGTCGACCCGCTGCGCTGACCACAGACCGGCATCGAGTCGTCAGGGGCGGCGCATCGGCCCGCCCCTGACGACGATTCC
CGCTTTCTCGAGGAGGACCC

Downstream 100 bases:

>100_bases
CACCGTCATCGCACGGAAAGCCACGGAAAGGCACGGCACGGAAATCGGGCGCGTCCCGGGGCCAAGATTGCCGAAGTGCC
GTATCCGCGCGGTACCGTCA

Product: GreA/GreB family elongation factor

Products: NA

Alternate protein names: Transcript cleavage factor greA [H]

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MTTAQRVWMTPVAYRRLQDELTELRTLIANEAPDDGQENTVAVQRARQTRIQQIHDLLLNAVVGEDPPDDGVAEPGMVLT
VRFDQTGDEETFLLGVRGAEYGDLEVYSVSSPLGEALIGARPGDRRTYEVPSGASVPVTLLKAVPFGMHHPRG

Sequences:

>Translated_153_residues
MTTAQRVWMTPVAYRRLQDELTELRTLIANEAPDDGQENTVAVQRARQTRIQQIHDLLLNAVVGEDPPDDGVAEPGMVLT
VRFDQTGDEETFLLGVRGAEYGDLEVYSVSSPLGEALIGARPGDRRTYEVPSGASVPVTLLKAVPFGMHHPRG
>Mature_152_residues
TTAQRVWMTPVAYRRLQDELTELRTLIANEAPDDGQENTVAVQRARQTRIQQIHDLLLNAVVGEDPPDDGVAEPGMVLTV
RFDQTGDEETFLLGVRGAEYGDLEVYSVSSPLGEALIGARPGDRRTYEVPSGASVPVTLLKAVPFGMHHPRG

Specific function: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary

COG id: COG0782

COG function: function code K; Transcription elongation factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the greA/greB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018151
- InterPro:   IPR006359
- InterPro:   IPR001437
- InterPro:   IPR022691 [H]

Pfam domain/function: PF01272 GreA_GreB; PF03449 GreA_GreB_N [H]

EC number: NA

Molecular weight: Translated: 16752; Mature: 16621

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00830 GREAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAQRVWMTPVAYRRLQDELTELRTLIANEAPDDGQENTVAVQRARQTRIQQIHDLLLN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AVVGEDPPDDGVAEPGMVLTVRFDQTGDEETFLLGVRGAEYGDLEVYSVSSPLGEALIGA
HHHCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCEEEEECCCCHHHHHHCC
RPGDRRTYEVPSGASVPVTLLKAVPFGMHHPRG
CCCCCCEEECCCCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TTAQRVWMTPVAYRRLQDELTELRTLIANEAPDDGQENTVAVQRARQTRIQQIHDLLLN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AVVGEDPPDDGVAEPGMVLTVRFDQTGDEETFLLGVRGAEYGDLEVYSVSSPLGEALIGA
HHHCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCEEEEECCCCHHHHHHCC
RPGDRRTYEVPSGASVPVTLLKAVPFGMHHPRG
CCCCCCEEECCCCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA