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The map label for this gene is selA [H]

Identifier: 119871329

GI number: 119871329

Start: 5539663

End: 5540940

Strand: Direct

Name: selA [H]

Synonym: Mkms_5303

Alternate gene names: 119871329

Gene position: 5539663-5540940 (Clockwise)

Preceding gene: 119871326

Following gene: 119871330

Centisome position: 96.56

GC content: 74.02

Gene sequence:

>1278_bases
ATGACCGACCCGCGCCGGCGCGTGCCCCGCACCGATGCCCTGCTCGCCGACCCCCGGCTGGCCGAGGCCGCGCGGGTACT
GGGCCGCACGCTGGTGAAAACGGTGATCGCCGACGCGCAGCAGCGCGCCCGCGCCGGTGACATCACGCCCGAACACGTCG
CCGACCACGCGGTCGCCGCGCTGCCGTCGGCGGCGGCGAGCCTGCGGCCGGTGATCAACGCGACCGGTGTGGTCGTCCAC
ACCAACCTCGGCCGCGCACCGCTGTCCCGGGCGGCCGTCGACGCGGTGGTGACGGCCGGCGGCGCGACCGACGTCGAATT
CGACCTCGCCACCGGCCTGCGCGCCCGCCGGGGCCGCGGGGCGTTGGCCGCACTGGCTCGGGCGGTGCCCACCGCCGGTG
GTGTACACGTGGTCAACAACAATGCCGCCGCGCTGCTGCTGGCCGCGATGACGCTGGCGAGTGGGCGTGAAATCGTCATC
AGCCGAGGCGAACTCATCGAGATCGGCGACGGCTTCCGCATCCCCGAACTCCTCGAATCGACCGGCGCGCGCATCCGCGA
GGTCGGCACCACCAACCGCACGCACCTGCGCGACTACGCCGACGCCATCGGCCCGGACACCGGGTTCGTACTCAAGGTGC
ACCCGTCGAACTACCACGTCACCGGCTTCACCAAGGCCGTGAGCATCACCGAGTTGGCCCGGCTCGACGCGCCGTTGGTC
GTCGACATCGGCTCGGGGCTGCTGACCCCGCACCCGGTCCTGCCCGACGAACCGGATGCCACGACGGCGCTGCGCGCCGG
CGCCGACCTCGTCACCGCCAGCGGGGACAAACTGCTCGGCGGCCCGCAGGCGGGGCTGCTGTTCGGCACCGCGGACCTGA
TCGAACGGCTCCGCAGGCATCCCGCCGCCCGCGCCCTGCGGGTCGACAAGCTCACCCTCGCCGCGCTCGAGGCGACGCTG
GTGGGCCCGCCGACACCGGTCGAACGCGCGTTGACCGCCGACCTCGCCGATCTGCGGGAGCGCGCGCAGCGCCTGGCCAC
GCAGCTTCCGGACGCGCAGGCCGTCGACTGTGTCGCGGCGGTCGGCGGCGGCGGCGCCCCCGAGGTCACCCTGCCCAGCG
CAGGCGTCAGCCTGCCCGAATCGTTCGCCGCGGCGCTGCGCGCGGGAACACCACCGGTGGTGGGCCGCGTCGAATCCGGC
CGCTGCGTCCTCGACCTGCGCACGGTCGATCCGGAGGAGGATGCGCGGCTGCTCGAGGCCATCAGCAGATGTACGTAG

Upstream 100 bases:

>100_bases
CGGGTTCGATTCCCGTCCGCCTCCGCCATCGTTCTTGTGATTTCGGCGTGCTGGGTCGCGCAGGGCGCGACCGCGCACGC
CGAAATCACGTGGGTGGGCG

Downstream 100 bases:

>100_bases
TCGCCACCGCCGGACACGTCGACCACGGCAAGTCGACGCTGGTGCAGCGGCTCACCGGGATGTGGCCCGACCGGCTCGCC
GAGGAGCAGCGCCGCGGCCT

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MTDPRRRVPRTDALLADPRLAEAARVLGRTLVKTVIADAQQRARAGDITPEHVADHAVAALPSAAASLRPVINATGVVVH
TNLGRAPLSRAAVDAVVTAGGATDVEFDLATGLRARRGRGALAALARAVPTAGGVHVVNNNAAALLLAAMTLASGREIVI
SRGELIEIGDGFRIPELLESTGARIREVGTTNRTHLRDYADAIGPDTGFVLKVHPSNYHVTGFTKAVSITELARLDAPLV
VDIGSGLLTPHPVLPDEPDATTALRAGADLVTASGDKLLGGPQAGLLFGTADLIERLRRHPAARALRVDKLTLAALEATL
VGPPTPVERALTADLADLRERAQRLATQLPDAQAVDCVAAVGGGGAPEVTLPSAGVSLPESFAAALRAGTPPVVGRVESG
RCVLDLRTVDPEEDARLLEAISRCT

Sequences:

>Translated_425_residues
MTDPRRRVPRTDALLADPRLAEAARVLGRTLVKTVIADAQQRARAGDITPEHVADHAVAALPSAAASLRPVINATGVVVH
TNLGRAPLSRAAVDAVVTAGGATDVEFDLATGLRARRGRGALAALARAVPTAGGVHVVNNNAAALLLAAMTLASGREIVI
SRGELIEIGDGFRIPELLESTGARIREVGTTNRTHLRDYADAIGPDTGFVLKVHPSNYHVTGFTKAVSITELARLDAPLV
VDIGSGLLTPHPVLPDEPDATTALRAGADLVTASGDKLLGGPQAGLLFGTADLIERLRRHPAARALRVDKLTLAALEATL
VGPPTPVERALTADLADLRERAQRLATQLPDAQAVDCVAAVGGGGAPEVTLPSAGVSLPESFAAALRAGTPPVVGRVESG
RCVLDLRTVDPEEDARLLEAISRCT
>Mature_424_residues
TDPRRRVPRTDALLADPRLAEAARVLGRTLVKTVIADAQQRARAGDITPEHVADHAVAALPSAAASLRPVINATGVVVHT
NLGRAPLSRAAVDAVVTAGGATDVEFDLATGLRARRGRGALAALARAVPTAGGVHVVNNNAAALLLAAMTLASGREIVIS
RGELIEIGDGFRIPELLESTGARIREVGTTNRTHLRDYADAIGPDTGFVLKVHPSNYHVTGFTKAVSITELARLDAPLVV
DIGSGLLTPHPVLPDEPDATTALRAGADLVTASGDKLLGGPQAGLLFGTADLIERLRRHPAARALRVDKLTLAALEATLV
GPPTPVERALTADLADLRERAQRLATQLPDAQAVDCVAAVGGGGAPEVTLPSAGVSLPESFAAALRAGTPPVVGRVESGR
CVLDLRTVDPEEDARLLEAISRCT

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=454, Percent_Identity=40.7488986784141, Blast_Score=263, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 43989; Mature: 43858

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS01347 MRAY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPRRRVPRTDALLADPRLAEAARVLGRTLVKTVIADAQQRARAGDITPEHVADHAVAA
CCCCHHCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LPSAAASLRPVINATGVVVHTNLGRAPLSRAAVDAVVTAGGATDVEFDLATGLRARRGRG
CCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHCCHHHCCCH
ALAALARAVPTAGGVHVVNNNAAALLLAAMTLASGREIVISRGELIEIGDGFRIPELLES
HHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCEEEECCCCCCHHHHHH
TGARIREVGTTNRTHLRDYADAIGPDTGFVLKVHPSNYHVTGFTKAVSITELARLDAPLV
CCCHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCCCEEEECHHHHHHHHHHHHCCCCEE
VDIGSGLLTPHPVLPDEPDATTALRAGADLVTASGDKLLGGPQAGLLFGTADLIERLRRH
EECCCCCCCCCCCCCCCCCHHHHHHCCCCEEECCCCCCCCCCCCCCEECHHHHHHHHHHC
PAARALRVDKLTLAALEATLVGPPTPVERALTADLADLRERAQRLATQLPDAQAVDCVAA
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VGGGGAPEVTLPSAGVSLPESFAAALRAGTPPVVGRVESGRCVLDLRTVDPEEDARLLEA
HCCCCCCCEECCCCCCCCHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHH
ISRCT
HHHCC
>Mature Secondary Structure 
TDPRRRVPRTDALLADPRLAEAARVLGRTLVKTVIADAQQRARAGDITPEHVADHAVAA
CCCHHCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LPSAAASLRPVINATGVVVHTNLGRAPLSRAAVDAVVTAGGATDVEFDLATGLRARRGRG
CCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHCCHHHCCCH
ALAALARAVPTAGGVHVVNNNAAALLLAAMTLASGREIVISRGELIEIGDGFRIPELLES
HHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCEEEECCCCCCHHHHHH
TGARIREVGTTNRTHLRDYADAIGPDTGFVLKVHPSNYHVTGFTKAVSITELARLDAPLV
CCCHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCCCEEEECHHHHHHHHHHHHCCCCEE
VDIGSGLLTPHPVLPDEPDATTALRAGADLVTASGDKLLGGPQAGLLFGTADLIERLRRH
EECCCCCCCCCCCCCCCCCHHHHHHCCCCEEECCCCCCCCCCCCCCEECHHHHHHHHHHC
PAARALRVDKLTLAALEATLVGPPTPVERALTADLADLRERAQRLATQLPDAQAVDCVAA
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VGGGGAPEVTLPSAGVSLPESFAAALRAGTPPVVGRVESGRCVLDLRTVDPEEDARLLEA
HCCCCCCCEECCCCCCCCHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHH
ISRCT
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA