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The map label for this gene is nodG [H]

Identifier: 119871326

GI number: 119871326

Start: 5536993

End: 5538039

Strand: Direct

Name: nodG [H]

Synonym: Mkms_5300

Alternate gene names: 119871326

Gene position: 5536993-5538039 (Clockwise)

Preceding gene: 119871324

Following gene: 119871329

Centisome position: 96.51

GC content: 71.44

Gene sequence:

>1047_bases
GTGGCTGCTGCGCGCGGTGTCTGCGGTGTTGCCGCGCCGGGCGCCCAAGAAGTCGGTGTGGGTGCCCGCCGCGCCGTCCT
ACCTGAGTCATCAGCTCAGAATCCGCTGACGGTGATCGACGATGCGGTGCGGTTGGCCGGTCGGACCGCGATCCGGTTGG
CCCGCGGGATCCCCGTGGTCGGCAACCGGTTCGGCGCACCCCCGCATCTGGACCTGGACGGCCGGGTCGTGTTCGTCACC
GGCGCGGCACGCGGGCTCGGCGCGCAGATCGCCCGCCAGGCGCACGCGCGCGGCGCTCAGGTGGTGCTCGTCGGGCGCAC
CCTGAAACCGCTGGAGGATCTCGCCGCCGAACTCGGCGACGGGGCGGCCGCCTTCGAGGCCGACGTCACCGACGCCCCGG
CTTTGCGACGCGCCGCCGAGGGTGCGGTCGCCGCGTTCGGCGGGATCGACGTCGTGGTGGCCAACGCCGGGATCGCGCCG
CCGTCGGAGACGGTCGCCACCATCGACCCGGACGAGTTCGAGCACACCGTCGAGGTCGACCTGCTCGGCCAGTGGCGCAC
CGTACGCGCGACGCTGCCCGCCGTGATCGCGGCCCGCGGACACATCGCGTTCGTCGGCTCGATCTACGCATTCTTCAACG
GTGTGCTCGCCGCCCCCTACGCGGTCAGTAAGGCCGGGGTGGAACAGCTTTCGCGTGCCCTGCGGGTGGAGCTGGCGCAG
CACGGTGTCACCGCGGGCATCGCCTACCTCGGTTTCATCGACACCGATCTGACCAGCGATGCCTTCGCCGACGAACACGC
CGCCGCGATCCGTTCGGCGGCGCCCGGTTTCATCACCCGGCCGATGAGTGCCGAATCGGCCGCCGCCGCCGTGCTCTCGG
GTGTCGAACGCCGTGCCGCGCAGGTCACCGCACCCGCGTGGGTGGGTCCGGTGCTGGCGGCGCGCAGCCTCACCACCGCC
GTGATGGACGACGTCCTGATGCACAACCCGCGAGTCAGCGATGCGGTACTCAGCGCCGAAGACGATGTGGCGCAGAGAGA
TTCATAA

Upstream 100 bases:

>100_bases
GCGGACGACCGTAACGGTTTGCCTCGGCCGCCGACGGGTATTTCAAGATCCCGTCACCTTACGGAAGGGAGCAGGCGATG
AGCACTCCGATGCCTCGGCC

Downstream 100 bases:

>100_bases
CCGTTCAGTCGGGCCGTACCGTGCTCACGCAGAACGGGTGGCCGACCGGGTCGAGCAGCACCCGCCACGCCTTGGCCGCG
GGCTGAAACTCGGCCTCCGT

Product: short chain dehydrogenase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MAAARGVCGVAAPGAQEVGVGARRAVLPESSAQNPLTVIDDAVRLAGRTAIRLARGIPVVGNRFGAPPHLDLDGRVVFVT
GAARGLGAQIARQAHARGAQVVLVGRTLKPLEDLAAELGDGAAAFEADVTDAPALRRAAEGAVAAFGGIDVVVANAGIAP
PSETVATIDPDEFEHTVEVDLLGQWRTVRATLPAVIAARGHIAFVGSIYAFFNGVLAAPYAVSKAGVEQLSRALRVELAQ
HGVTAGIAYLGFIDTDLTSDAFADEHAAAIRSAAPGFITRPMSAESAAAAVLSGVERRAAQVTAPAWVGPVLAARSLTTA
VMDDVLMHNPRVSDAVLSAEDDVAQRDS

Sequences:

>Translated_348_residues
MAAARGVCGVAAPGAQEVGVGARRAVLPESSAQNPLTVIDDAVRLAGRTAIRLARGIPVVGNRFGAPPHLDLDGRVVFVT
GAARGLGAQIARQAHARGAQVVLVGRTLKPLEDLAAELGDGAAAFEADVTDAPALRRAAEGAVAAFGGIDVVVANAGIAP
PSETVATIDPDEFEHTVEVDLLGQWRTVRATLPAVIAARGHIAFVGSIYAFFNGVLAAPYAVSKAGVEQLSRALRVELAQ
HGVTAGIAYLGFIDTDLTSDAFADEHAAAIRSAAPGFITRPMSAESAAAAVLSGVERRAAQVTAPAWVGPVLAARSLTTA
VMDDVLMHNPRVSDAVLSAEDDVAQRDS
>Mature_347_residues
AAARGVCGVAAPGAQEVGVGARRAVLPESSAQNPLTVIDDAVRLAGRTAIRLARGIPVVGNRFGAPPHLDLDGRVVFVTG
AARGLGAQIARQAHARGAQVVLVGRTLKPLEDLAAELGDGAAAFEADVTDAPALRRAAEGAVAAFGGIDVVVANAGIAPP
SETVATIDPDEFEHTVEVDLLGQWRTVRATLPAVIAARGHIAFVGSIYAFFNGVLAAPYAVSKAGVEQLSRALRVELAQH
GVTAGIAYLGFIDTDLTSDAFADEHAAAIRSAAPGFITRPMSAESAAAAVLSGVERRAAQVTAPAWVGPVLAARSLTTAV
MDDVLMHNPRVSDAVLSAEDDVAQRDS

Specific function: Proposed to modify Nod factor fatty acyl chain [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=201, Percent_Identity=32.3383084577114, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI19743808, Length=212, Percent_Identity=32.5471698113208, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI150247226, Length=193, Percent_Identity=32.6424870466321, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI7706318, Length=215, Percent_Identity=27.4418604651163, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI210032110, Length=194, Percent_Identity=28.8659793814433, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI40254992, Length=193, Percent_Identity=29.0155440414508, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI22507405, Length=202, Percent_Identity=29.7029702970297, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI142976729, Length=237, Percent_Identity=27.8481012658228, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI32483357, Length=199, Percent_Identity=27.1356783919598, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI59889578, Length=206, Percent_Identity=27.6699029126214, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1787335, Length=207, Percent_Identity=30.9178743961353, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082100, Length=197, Percent_Identity=32.994923857868, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787820, Length=168, Percent_Identity=31.547619047619, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789208, Length=204, Percent_Identity=26.4705882352941, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=198, Percent_Identity=31.3131313131313, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32563809, Length=198, Percent_Identity=31.3131313131313, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=180, Percent_Identity=30.5555555555556, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=192, Percent_Identity=30.2083333333333, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=258, Percent_Identity=24.031007751938, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=202, Percent_Identity=28.2178217821782, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=195, Percent_Identity=28.7179487179487, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=148, Percent_Identity=28.3783783783784, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=209, Percent_Identity=25.8373205741627, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=205, Percent_Identity=29.2682926829268, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=202, Percent_Identity=25.2475247524752, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=194, Percent_Identity=27.8350515463918, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=233, Percent_Identity=29.1845493562232, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322226, Length=188, Percent_Identity=29.2553191489362, Blast_Score=76, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6324126, Length=192, Percent_Identity=28.6458333333333, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322067, Length=189, Percent_Identity=26.984126984127, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI23397609, Length=192, Percent_Identity=35.4166666666667, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644339, Length=194, Percent_Identity=29.8969072164948, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571526, Length=201, Percent_Identity=30.8457711442786, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357041, Length=199, Percent_Identity=30.6532663316583, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21358495, Length=252, Percent_Identity=25.7936507936508, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640492, Length=235, Percent_Identity=28.0851063829787, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24639444, Length=191, Percent_Identity=31.413612565445, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24649181, Length=240, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357673, Length=187, Percent_Identity=28.8770053475936, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI281364892, Length=176, Percent_Identity=28.9772727272727, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 35573; Mature: 35441

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAARGVCGVAAPGAQEVGVGARRAVLPESSAQNPLTVIDDAVRLAGRTAIRLARGIPVV
CCCCCCCCCCCCCCCHHHCCCCHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
GNRFGAPPHLDLDGRVVFVTGAARGLGAQIARQAHARGAQVVLVGRTLKPLEDLAAELGD
CCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCC
GAAAFEADVTDAPALRRAAEGAVAAFGGIDVVVANAGIAPPSETVATIDPDEFEHTVEVD
CCEEEECCCCCCHHHHHHHCCCCEECCCEEEEEECCCCCCCCCCEEECCHHHCCEEEEEE
LLGQWRTVRATLPAVIAARGHIAFVGSIYAFFNGVLAAPYAVSKAGVEQLSRALRVELAQ
ECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
HGVTAGIAYLGFIDTDLTSDAFADEHAAAIRSAAPGFITRPMSAESAAAAVLSGVERRAA
CCHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHH
QVTAPAWVGPVLAARSLTTAVMDDVLMHNPRVSDAVLSAEDDVAQRDS
HCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHCCCC
>Mature Secondary Structure 
AAARGVCGVAAPGAQEVGVGARRAVLPESSAQNPLTVIDDAVRLAGRTAIRLARGIPVV
CCCCCCCCCCCCCCHHHCCCCHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
GNRFGAPPHLDLDGRVVFVTGAARGLGAQIARQAHARGAQVVLVGRTLKPLEDLAAELGD
CCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCC
GAAAFEADVTDAPALRRAAEGAVAAFGGIDVVVANAGIAPPSETVATIDPDEFEHTVEVD
CCEEEECCCCCCHHHHHHHCCCCEECCCEEEEEECCCCCCCCCCEEECCHHHCCEEEEEE
LLGQWRTVRATLPAVIAARGHIAFVGSIYAFFNGVLAAPYAVSKAGVEQLSRALRVELAQ
ECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
HGVTAGIAYLGFIDTDLTSDAFADEHAAAIRSAAPGFITRPMSAESAAAAVLSGVERRAA
CCHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHH
QVTAPAWVGPVLAARSLTTAVMDDVLMHNPRVSDAVLSAEDDVAQRDS
HCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9100384 [H]