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The map label for this gene is msrB2 [H]

Identifier: 119871206

GI number: 119871206

Start: 5425880

End: 5426341

Strand: Direct

Name: msrB2 [H]

Synonym: Mkms_5179

Alternate gene names: 119871206

Gene position: 5425880-5426341 (Clockwise)

Preceding gene: 119871202

Following gene: 119871207

Centisome position: 94.57

GC content: 64.07

Gene sequence:

>462_bases
GTGGCACGGGCTTACAACAGGAATCCTGCCGCGGTGGACGCGCTGTCCCCCGAGCAGTACCACGTCACGCAGGAGGGCGG
CACCGAGCGGCCGTTCACCGGTGAGTACTTGGACAACCACGAGCCGGGTATCTACGTCGACGTCGTCTCGGGCGAACCGC
TGTTCGCCTCGGTCGACAAGTTCGACAGCGGCAGCGGCTGGCCGAGCTTCACCCGGCCGATCGACGCCGTAAACATCAAA
GAGAAAAAGGACTTCAGCCATCTGATGATCCGCACCGAGGTGCGCTCGGCGCACGGCGACAGCCACCTCGGCCACGTCTT
CACCGACGGACCCCGCGCGCAAGGCGGGCTGCGGTACTGCATCAACTCCGCGGCGTTGCGGTTCATCCACCTCGACGACC
TCGAGGCGCAAGGATATGGCGAATACAGGACGTTGTTCACCAAGGAGGACGCACAGTCATGA

Upstream 100 bases:

>100_bases
GAAACACGTTCTAGCCACCTTTGTCGAGGGTGAACACGCGGCGAGCTGGGATGATCGCGGCCCGGCCTACGGTTGTAGAG
GGTGCACACGAGGAGGTCAT

Downstream 100 bases:

>100_bases
GTGACCACAAGAAGGCCATCCTGGCGGGCGGCTGCTTCTGGGGTATGCAGGATCTGATCCGCAAGCAACCGGGTGTGGTG
TCGACCCGCGTCGGCTACAC

Product: methionine-R-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase 2 [H]

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MARAYNRNPAAVDALSPEQYHVTQEGGTERPFTGEYLDNHEPGIYVDVVSGEPLFASVDKFDSGSGWPSFTRPIDAVNIK
EKKDFSHLMIRTEVRSAHGDSHLGHVFTDGPRAQGGLRYCINSAALRFIHLDDLEAQGYGEYRTLFTKEDAQS

Sequences:

>Translated_153_residues
MARAYNRNPAAVDALSPEQYHVTQEGGTERPFTGEYLDNHEPGIYVDVVSGEPLFASVDKFDSGSGWPSFTRPIDAVNIK
EKKDFSHLMIRTEVRSAHGDSHLGHVFTDGPRAQGGLRYCINSAALRFIHLDDLEAQGYGEYRTLFTKEDAQS
>Mature_152_residues
ARAYNRNPAAVDALSPEQYHVTQEGGTERPFTGEYLDNHEPGIYVDVVSGEPLFASVDKFDSGSGWPSFTRPIDAVNIKE
KKDFSHLMIRTEVRSAHGDSHLGHVFTDGPRAQGGLRYCINSAALRFIHLDDLEAQGYGEYRTLFTKEDAQS

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=118, Percent_Identity=56.7796610169492, Blast_Score=129, Evalue=7e-31,
Organism=Homo sapiens, GI301336162, Length=118, Percent_Identity=56.7796610169492, Blast_Score=129, Evalue=7e-31,
Organism=Homo sapiens, GI73089054, Length=118, Percent_Identity=56.7796610169492, Blast_Score=129, Evalue=7e-31,
Organism=Homo sapiens, GI37620216, Length=118, Percent_Identity=56.7796610169492, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI117606353, Length=121, Percent_Identity=47.1074380165289, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI1788077, Length=114, Percent_Identity=52.6315789473684, Blast_Score=123, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17553450, Length=133, Percent_Identity=45.1127819548872, Blast_Score=106, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI115532676, Length=129, Percent_Identity=45.7364341085271, Blast_Score=106, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319816, Length=121, Percent_Identity=38.8429752066116, Blast_Score=84, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45553335, Length=119, Percent_Identity=49.5798319327731, Blast_Score=120, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21356369, Length=119, Percent_Identity=49.5798319327731, Blast_Score=120, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24645799, Length=119, Percent_Identity=49.5798319327731, Blast_Score=120, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24645801, Length=130, Percent_Identity=45.3846153846154, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24645804, Length=130, Percent_Identity=45.3846153846154, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI221378664, Length=116, Percent_Identity=48.2758620689655, Blast_Score=114, Evalue=3e-26,
Organism=Drosophila melanogaster, GI221378662, Length=123, Percent_Identity=45.5284552845528, Blast_Score=111, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 17034; Mature: 16903

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARAYNRNPAAVDALSPEQYHVTQEGGTERPFTGEYLDNHEPGIYVDVVSGEPLFASVDK
CCCCCCCCCCEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCC
FDSGSGWPSFTRPIDAVNIKEKKDFSHLMIRTEVRSAHGDSHLGHVFTDGPRAQGGLRYC
CCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEEEHHHCCCCCCCCEEECCCCCCCCHHHHH
INSAALRFIHLDDLEAQGYGEYRTLFTKEDAQS
HHHHEEEEEEECCCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
ARAYNRNPAAVDALSPEQYHVTQEGGTERPFTGEYLDNHEPGIYVDVVSGEPLFASVDK
CCCCCCCCCEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCC
FDSGSGWPSFTRPIDAVNIKEKKDFSHLMIRTEVRSAHGDSHLGHVFTDGPRAQGGLRYC
CCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEEEHHHCCCCCCCCEEECCCCCCCCHHHHH
INSAALRFIHLDDLEAQGYGEYRTLFTKEDAQS
HHHHEEEEEEECCCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]