Click here to switch to the map view.

The map label for this gene is dinB2 [H]

Identifier: 119871174

GI number: 119871174

Start: 5392582

End: 5393805

Strand: Direct

Name: dinB2 [H]

Synonym: Mkms_5147

Alternate gene names: 119871174

Gene position: 5392582-5393805 (Clockwise)

Preceding gene: 119871173

Following gene: 119871178

Centisome position: 93.99

GC content: 73.77

Gene sequence:

>1224_bases
ATGTTCGTGTCGGCTCCGGCTCGTGGTCACGCGCAGGCCAGCATCCTGCACGCTGACCTCGACTCCTTCTACGCCTCGGT
CGAGCAGCGCGACGATCCCGCGCTGCGCGGCCGGCCCGTCATCGTCGGCGGCGGGGTGGTGCTCGCGGCCAGCTACGAGG
CCAAGGCCTACGGCGTCCGCACCGCGATGGGCGGCCACCAGGCGCGGCGGCTGTGCCCGCAGGCGGTCGTCGTCCCGCCG
CGGATGGCCGCCTACTCCCAGGCCAGCGCCGCCGTGTTCGAGGTCTTCCGTGACACCACCCCGCTCGTCGAACCCCTCTC
GGTGGACGAGGCGTTCCTCGACGTCTCCGGGCTCGGCCGGGTCTCGGGCACTCCGGTGGCGATCGGCGCGCGCCTGCGGG
CCAGGGTGCGCGAGGAGGTCGGGCTGCCGATCACCGTCGGGATCGCGCGGACCAAGTTCCTCGCCAAGGTCGCCAGCCAG
GAGGGCAAACCGGACGGGCTGCTGCTGGTCCCGCCGGACCGCGAGCTGGCCTTCCTGCATCCGCTGCCGGTGCGGCGGCT
CTGGGGGGTCGGGGAGAAGACCGCCGCGAAGCTGCGCGCGCACGGCATCGAAACCGTCGCCGACGTCGCCGAACTCGGCG
AGTCGACGCTGAGCGCGATGGTCGGCGGCGCGATGGGCCGCCAGCTCTACGCGCTGTCGCACAACGTCGACCGTCGCCGG
GTGGTCACCGGCGTCCGGCGCCGCTCGGTCGGGGCGCAGCGGGCGCTGGGCCGCCGCGGCAACGCCATGACGGCCACCGA
GGTGGACGCCGTGGTGGTCAACCTGATCGACCGCATCACCCGCCGGATGCGCAACGCCGGTCGCACCGGCCGCACGGTCG
TGCTGCGGTTGCGCTTCGACGACTTCAGCCGCGTCACCCGGTCACACACCATGCCGCGCGCGACGGCGTCGACCGACGCC
GTGCTGGCCGCCGCACGCGATCTGGTCGCGGCGGCGGCCCCGGTGATCGCCGAGCGCGGGCTCACGCTGATCGGTTTCGC
GGTGTCCAACATCGACCGCGACGGCGCCCAGCAGCTCGAGTTGCCCTTCGGACACGCACCCGATGCGGGTGCGCTCGACG
CCGCGGTCGACGAGGTGCGCACCCGCTACGGCAACGCCGCCGTCACCCGCGGGGTGCTGCTCGGGCGTGATCCCGGTTTG
GAGATGCCGATGCTGCCGGACTGA

Upstream 100 bases:

>100_bases
CGGCATCCCGCCCGACCGGGTCCTCGACTCGCTCGTGCACGTGTGGACGTGTGCGGTGTACGGGGAATGCCGCTGACACG
TCGGACCCTCATGCGAACAT

Downstream 100 bases:

>100_bases
CCGTCAGGCGGGGACGACGCGGCCCCACACCCGGTGTTCGCCGAGGCTCTCGAGCAGCGCCGACGTCAGGCCCGCCGGGT
CCGACGCGCTGAGCACGCCT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 2 [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MFVSAPARGHAQASILHADLDSFYASVEQRDDPALRGRPVIVGGGVVLAASYEAKAYGVRTAMGGHQARRLCPQAVVVPP
RMAAYSQASAAVFEVFRDTTPLVEPLSVDEAFLDVSGLGRVSGTPVAIGARLRARVREEVGLPITVGIARTKFLAKVASQ
EGKPDGLLLVPPDRELAFLHPLPVRRLWGVGEKTAAKLRAHGIETVADVAELGESTLSAMVGGAMGRQLYALSHNVDRRR
VVTGVRRRSVGAQRALGRRGNAMTATEVDAVVVNLIDRITRRMRNAGRTGRTVVLRLRFDDFSRVTRSHTMPRATASTDA
VLAAARDLVAAAAPVIAERGLTLIGFAVSNIDRDGAQQLELPFGHAPDAGALDAAVDEVRTRYGNAAVTRGVLLGRDPGL
EMPMLPD

Sequences:

>Translated_407_residues
MFVSAPARGHAQASILHADLDSFYASVEQRDDPALRGRPVIVGGGVVLAASYEAKAYGVRTAMGGHQARRLCPQAVVVPP
RMAAYSQASAAVFEVFRDTTPLVEPLSVDEAFLDVSGLGRVSGTPVAIGARLRARVREEVGLPITVGIARTKFLAKVASQ
EGKPDGLLLVPPDRELAFLHPLPVRRLWGVGEKTAAKLRAHGIETVADVAELGESTLSAMVGGAMGRQLYALSHNVDRRR
VVTGVRRRSVGAQRALGRRGNAMTATEVDAVVVNLIDRITRRMRNAGRTGRTVVLRLRFDDFSRVTRSHTMPRATASTDA
VLAAARDLVAAAAPVIAERGLTLIGFAVSNIDRDGAQQLELPFGHAPDAGALDAAVDEVRTRYGNAAVTRGVLLGRDPGL
EMPMLPD
>Mature_407_residues
MFVSAPARGHAQASILHADLDSFYASVEQRDDPALRGRPVIVGGGVVLAASYEAKAYGVRTAMGGHQARRLCPQAVVVPP
RMAAYSQASAAVFEVFRDTTPLVEPLSVDEAFLDVSGLGRVSGTPVAIGARLRARVREEVGLPITVGIARTKFLAKVASQ
EGKPDGLLLVPPDRELAFLHPLPVRRLWGVGEKTAAKLRAHGIETVADVAELGESTLSAMVGGAMGRQLYALSHNVDRRR
VVTGVRRRSVGAQRALGRRGNAMTATEVDAVVVNLIDRITRRMRNAGRTGRTVVLRLRFDDFSRVTRSHTMPRATASTDA
VLAAARDLVAAAAPVIAERGLTLIGFAVSNIDRDGAQQLELPFGHAPDAGALDAAVDEVRTRYGNAAVTRGVLLGRDPGL
EMPMLPD

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI7706681, Length=271, Percent_Identity=28.0442804428044, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI84043967, Length=271, Percent_Identity=28.0442804428044, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI154350220, Length=392, Percent_Identity=24.7448979591837, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI7705344, Length=104, Percent_Identity=44.2307692307692, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI5729982, Length=127, Percent_Identity=33.0708661417323, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1786425, Length=363, Percent_Identity=35.5371900826446, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1787432, Length=205, Percent_Identity=34.6341463414634, Blast_Score=102, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI193205700, Length=383, Percent_Identity=25.065274151436, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17537959, Length=200, Percent_Identity=28, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI115534089, Length=117, Percent_Identity=44.4444444444444, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193205702, Length=201, Percent_Identity=25.3731343283582, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI19923006, Length=337, Percent_Identity=24.6290801186944, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21355641, Length=349, Percent_Identity=28.3667621776504, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24644984, Length=349, Percent_Identity=28.3667621776504, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24668444, Length=116, Percent_Identity=36.2068965517241, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 43313; Mature: 43313

Theoretical pI: Translated: 10.81; Mature: 10.81

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVSAPARGHAQASILHADLDSFYASVEQRDDPALRGRPVIVGGGVVLAASYEAKAYGVR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCCHHHHHH
TAMGGHQARRLCPQAVVVPPRMAAYSQASAAVFEVFRDTTPLVEPLSVDEAFLDVSGLGR
HHHCCHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCC
VSGTPVAIGARLRARVREEVGLPITVGIARTKFLAKVASQEGKPDGLLLVPPDRELAFLH
CCCCCEEEHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEC
PLPVRRLWGVGEKTAAKLRAHGIETVADVAELGESTLSAMVGGAMGRQLYALSHNVDRRR
CCCHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEHHCCCCHHH
VVTGVRRRSVGAQRALGRRGNAMTATEVDAVVVNLIDRITRRMRNAGRTGRTVVLRLRFD
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
DFSRVTRSHTMPRATASTDAVLAAARDLVAAAAPVIAERGLTLIGFAVSNIDRDGAQQLE
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCHHCC
LPFGHAPDAGALDAAVDEVRTRYGNAAVTRGVLLGRDPGLEMPMLPD
CCCCCCCCCCHHHHHHHHHHHHHCCHHHHHCEEEECCCCCCCCCCCC
>Mature Secondary Structure
MFVSAPARGHAQASILHADLDSFYASVEQRDDPALRGRPVIVGGGVVLAASYEAKAYGVR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCCHHHHHH
TAMGGHQARRLCPQAVVVPPRMAAYSQASAAVFEVFRDTTPLVEPLSVDEAFLDVSGLGR
HHHCCHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCC
VSGTPVAIGARLRARVREEVGLPITVGIARTKFLAKVASQEGKPDGLLLVPPDRELAFLH
CCCCCEEEHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEC
PLPVRRLWGVGEKTAAKLRAHGIETVADVAELGESTLSAMVGGAMGRQLYALSHNVDRRR
CCCHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEHHCCCCHHH
VVTGVRRRSVGAQRALGRRGNAMTATEVDAVVVNLIDRITRRMRNAGRTGRTVVLRLRFD
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
DFSRVTRSHTMPRATASTDAVLAAARDLVAAAAPVIAERGLTLIGFAVSNIDRDGAQQLE
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCHHCC
LPFGHAPDAGALDAAVDEVRTRYGNAAVTRGVLLGRDPGLEMPMLPD
CCCCCCCCCCHHHHHHHHHHHHHCCHHHHHCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]