Click here to switch to the map view.

The map label for this gene is yciR [C]

Identifier: 119870861

GI number: 119870861

Start: 5061971

End: 5063842

Strand: Direct

Name: yciR [C]

Synonym: Mkms_4833

Alternate gene names: 119870861

Gene position: 5061971-5063842 (Clockwise)

Preceding gene: 119870860

Following gene: 119870863

Centisome position: 88.23

GC content: 67.84

Gene sequence:

>1872_bases
ATGACCCGGACCCTCGATCAGGTCGTCACCGCGGCGGCCGCGGAGTTGATGGCGGCCACCGCCACCAACGTGGTCGAAAG
CTGCACCCGGGTCCTCGCCGACGTCGTCGCCCACCTGGGGGTCGACTTCAGCTTCCTGCGGCACAACGACCACACCATCA
AGGCCACCAAGCTGGTCGCCGAATGGCCGATCCGCGACTACATCCCGGACCCGGACCCGATCGGCACCATCTATTTCGCC
GAGGCCGACCCCGTCTTCCGGCAGGCCGAGTACCTCAAGACACCGCTCATCGTGCGTCCCGAACCGGACAACGACGACTA
CCAGCGCCGGATCGAGGAGGGCCGAGGCGTGCCGTCGGTGTCGATGGCATGCGTGCCATTGCTCTCGGGTGAGATGACCT
CTGGCATCCTCGGCTTCATCAAGATCGGTGACCGTGAGTGGACCACCGAGGAGCAGAACGCGCTGCAGGCGATCGCCACG
CTGTTCGCCCAGCTGCAGGCCCGCATCGCCGCCGAGGAGCAGCTCCAGTACCTCGCCGAGCACGACGATCTGTCCGGACT
GCTGAACCGCCGGGCGCTGATGGCGCACCTCGGCCTACGGCTCGCCGAGGGTCAGCCCGGTCCGGTGTCGGTGCTGTTCC
TCGATCTCGACCGGCTCAAGACCGTCAACGACTATCTGGGCCACAGCGCCGGTGACCAGTTCATCAAGATGTTCGCCGAG
CGGTTGCGGGCGGGCACCGAGAAGCCCGCCGTGATCGCCCGCGTCGGCGGTGACGAGTTCGTGGTGGTCCCCGACGAACC
GATGGACGTCGTGGCGGTCGAGAGCTTCGCCCGCCGGCTGCAGACGTGGTTGCAGCGGCGGGTCGTCATCGACGGCGAGA
TGCTTGCGCGCACTGTGAGCATCGGCGTCGCCGTCGGCACTCCCGGTGACGACACCACATCGGATCTGCTGCGCCGCGCC
GACCAGGCGGCCCTGTCGGCGAAGAGCACCGGCGGCAGCAAGACGGCGGTGTTCACCACGGAGATGGCGTCCCAGCACGC
CATCCGCAACGACATCGAACTGCACCTCGAGGGTGTGATCGACGAGGCGAGCAGCGCGCTCGTCCTGCACTACCTACCCG
AGATCGACATGCGCACCGGGAAGGTGCTCGGCACCGAGGCACTGGTCCGCTGGCGGCATCCGACCAGGGGGCTGCTGCTG
CCCGAGTCGTTCATCGGGGTGGCCGAATCCATCAATCTCGCAGGCAAACTCGGCCGACTGGTGATGCGCTCGGCATGCGC
GGACTTCGCCCGCTGGAGGTCGCGCCGCACCGCAGGCGACGCCATCCTGCGGATCAACGTCTCACCCGTGCAACTGGTTT
CGGATGGATTCGCGGCGACCGTCGCCGGCACCCTCGACGAGTTCGGGGTCGACGGTTCCGCGGTGTGCCTGGAGATCACC
GAGAGCGTGGTGGTCCAGGACATCGAGGCCACCCGCCACACACTGGCCGCACTCAAAGAGGTCGGCGTGCGCATCGCGAT
CGACGACTTCGGTACCGGCTACAGCGTTCTCACGCACCTGAAGTCACTGCCCGTCGACACCGTCAAGATCGACCGCAGCT
TCGTCCGTGACCTCGGCGCCAGCCCCGGCGACCTGGCGATCGTGCGGGCCATCCTGGCGTTGGCCGATGCGTTCGAACTC
GAGGTGGTGGCCGAAGGGGTGGAGACCGTCGCGGCCGCCAAGACGCTGCTCGAACTGGGTTGCCCACGCGCGCAGGGGTT
CATGCTGTCGCGTCCGGTCGACGCGGCGGCGATGGAGGCGTTGTTCCGTGAGGGGCGCATCGCCGTCGACGCGTGGCGTG
ACGACGCCGCAACCGTGAACGGACGGCAGTAG

Upstream 100 bases:

>100_bases
CGCCGACGGCCGCTTCGCGCTCGCGGGAGAGGGTTCGTGAACGCAGCCGTACCAGCGTGGTCGCCCACTTGGGCACACCT
CTGCGGGATACCGTGATCAG

Downstream 100 bases:

>100_bases
CACTAGGCGGTCTGCTCCGCCTGGGTGTCGTTGCAGCAGAACCGCCTGCGGTAGTCGGTGGGCGTCACACCGATGATGCG
CCGGAAGTGGTGGCGCAGCA

Product: GAF sensor-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 623; Mature: 622

Protein sequence:

>623_residues
MTRTLDQVVTAAAAELMAATATNVVESCTRVLADVVAHLGVDFSFLRHNDHTIKATKLVAEWPIRDYIPDPDPIGTIYFA
EADPVFRQAEYLKTPLIVRPEPDNDDYQRRIEEGRGVPSVSMACVPLLSGEMTSGILGFIKIGDREWTTEEQNALQAIAT
LFAQLQARIAAEEQLQYLAEHDDLSGLLNRRALMAHLGLRLAEGQPGPVSVLFLDLDRLKTVNDYLGHSAGDQFIKMFAE
RLRAGTEKPAVIARVGGDEFVVVPDEPMDVVAVESFARRLQTWLQRRVVIDGEMLARTVSIGVAVGTPGDDTTSDLLRRA
DQAALSAKSTGGSKTAVFTTEMASQHAIRNDIELHLEGVIDEASSALVLHYLPEIDMRTGKVLGTEALVRWRHPTRGLLL
PESFIGVAESINLAGKLGRLVMRSACADFARWRSRRTAGDAILRINVSPVQLVSDGFAATVAGTLDEFGVDGSAVCLEIT
ESVVVQDIEATRHTLAALKEVGVRIAIDDFGTGYSVLTHLKSLPVDTVKIDRSFVRDLGASPGDLAIVRAILALADAFEL
EVVAEGVETVAAAKTLLELGCPRAQGFMLSRPVDAAAMEALFREGRIAVDAWRDDAATVNGRQ

Sequences:

>Translated_623_residues
MTRTLDQVVTAAAAELMAATATNVVESCTRVLADVVAHLGVDFSFLRHNDHTIKATKLVAEWPIRDYIPDPDPIGTIYFA
EADPVFRQAEYLKTPLIVRPEPDNDDYQRRIEEGRGVPSVSMACVPLLSGEMTSGILGFIKIGDREWTTEEQNALQAIAT
LFAQLQARIAAEEQLQYLAEHDDLSGLLNRRALMAHLGLRLAEGQPGPVSVLFLDLDRLKTVNDYLGHSAGDQFIKMFAE
RLRAGTEKPAVIARVGGDEFVVVPDEPMDVVAVESFARRLQTWLQRRVVIDGEMLARTVSIGVAVGTPGDDTTSDLLRRA
DQAALSAKSTGGSKTAVFTTEMASQHAIRNDIELHLEGVIDEASSALVLHYLPEIDMRTGKVLGTEALVRWRHPTRGLLL
PESFIGVAESINLAGKLGRLVMRSACADFARWRSRRTAGDAILRINVSPVQLVSDGFAATVAGTLDEFGVDGSAVCLEIT
ESVVVQDIEATRHTLAALKEVGVRIAIDDFGTGYSVLTHLKSLPVDTVKIDRSFVRDLGASPGDLAIVRAILALADAFEL
EVVAEGVETVAAAKTLLELGCPRAQGFMLSRPVDAAAMEALFREGRIAVDAWRDDAATVNGRQ
>Mature_622_residues
TRTLDQVVTAAAAELMAATATNVVESCTRVLADVVAHLGVDFSFLRHNDHTIKATKLVAEWPIRDYIPDPDPIGTIYFAE
ADPVFRQAEYLKTPLIVRPEPDNDDYQRRIEEGRGVPSVSMACVPLLSGEMTSGILGFIKIGDREWTTEEQNALQAIATL
FAQLQARIAAEEQLQYLAEHDDLSGLLNRRALMAHLGLRLAEGQPGPVSVLFLDLDRLKTVNDYLGHSAGDQFIKMFAER
LRAGTEKPAVIARVGGDEFVVVPDEPMDVVAVESFARRLQTWLQRRVVIDGEMLARTVSIGVAVGTPGDDTTSDLLRRAD
QAALSAKSTGGSKTAVFTTEMASQHAIRNDIELHLEGVIDEASSALVLHYLPEIDMRTGKVLGTEALVRWRHPTRGLLLP
ESFIGVAESINLAGKLGRLVMRSACADFARWRSRRTAGDAILRINVSPVQLVSDGFAATVAGTLDEFGVDGSAVCLEITE
SVVVQDIEATRHTLAALKEVGVRIAIDDFGTGYSVLTHLKSLPVDTVKIDRSFVRDLGASPGDLAIVRAILALADAFELE
VVAEGVETVAAAKTLLELGCPRAQGFMLSRPVDAAAMEALFREGRIAVDAWRDDAATVNGRQ

Specific function: Unknown

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=433, Percent_Identity=33.4872979214781, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI87081921, Length=427, Percent_Identity=32.0843091334895, Blast_Score=201, Evalue=9e-53,
Organism=Escherichia coli, GI226510982, Length=429, Percent_Identity=29.1375291375291, Blast_Score=170, Evalue=3e-43,
Organism=Escherichia coli, GI1787055, Length=234, Percent_Identity=37.1794871794872, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1788502, Length=223, Percent_Identity=37.219730941704, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI87081743, Length=225, Percent_Identity=32, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1786507, Length=256, Percent_Identity=32.421875, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1790496, Length=225, Percent_Identity=32, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI87081845, Length=227, Percent_Identity=33.920704845815, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788849, Length=207, Percent_Identity=32.3671497584541, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI87082096, Length=198, Percent_Identity=33.8383838383838, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87081980, Length=225, Percent_Identity=32, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI87081881, Length=173, Percent_Identity=36.4161849710983, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI87081977, Length=196, Percent_Identity=32.1428571428571, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787262, Length=163, Percent_Identity=31.2883435582822, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788381, Length=185, Percent_Identity=28.6486486486486, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI145693134, Length=195, Percent_Identity=27.1794871794872, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787816, Length=154, Percent_Identity=29.2207792207792, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082007, Length=183, Percent_Identity=31.6939890710383, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87081974, Length=159, Percent_Identity=28.9308176100629, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1787410, Length=156, Percent_Identity=28.8461538461538, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1787802, Length=175, Percent_Identity=30.8571428571429, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786584, Length=168, Percent_Identity=27.9761904761905, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 67519; Mature: 67388

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTLDQVVTAAAAELMAATATNVVESCTRVLADVVAHLGVDFSFLRHNDHTIKATKLVA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEHHHHHH
EWPIRDYIPDPDPIGTIYFAEADPVFRQAEYLKTPLIVRPEPDNDDYQRRIEEGRGVPSV
HCCHHHCCCCCCCCCEEEEECCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCCCCH
SMACVPLLSGEMTSGILGFIKIGDREWTTEEQNALQAIATLFAQLQARIAAEEQLQYLAE
HHHHHHHHCCCHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDDLSGLLNRRALMAHLGLRLAEGQPGPVSVLFLDLDRLKTVNDYLGHSAGDQFIKMFAE
CCHHHHHHHHHHHHHHHCCEEECCCCCCEEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHH
RLRAGTEKPAVIARVGGDEFVVVPDEPMDVVAVESFARRLQTWLQRRVVIDGEMLARTVS
HHHCCCCCCEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHH
IGVAVGTPGDDTTSDLLRRADQAALSAKSTGGSKTAVFTTEMASQHAIRNDIELHLEGVI
EEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHCCHHHHHHHHH
DEASSALVLHYLPEIDMRTGKVLGTEALVRWRHPTRGLLLPESFIGVAESINLAGKLGRL
HCCCCEEEEEECCCCCCCCCCEECHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VMRSACADFARWRSRRTAGDAILRINVSPVQLVSDGFAATVAGTLDEFGVDGSAVCLEIT
HHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHH
ESVVVQDIEATRHTLAALKEVGVRIAIDDFGTGYSVLTHLKSLPVDTVKIDRSFVRDLGA
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCC
SPGDLAIVRAILALADAFELEVVAEGVETVAAAKTLLELGCPRAQGFMLSRPVDAAAMEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHH
LFREGRIAVDAWRDDAATVNGRQ
HHHCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
TRTLDQVVTAAAAELMAATATNVVESCTRVLADVVAHLGVDFSFLRHNDHTIKATKLVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEHHHHHH
EWPIRDYIPDPDPIGTIYFAEADPVFRQAEYLKTPLIVRPEPDNDDYQRRIEEGRGVPSV
HCCHHHCCCCCCCCCEEEEECCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCCCCH
SMACVPLLSGEMTSGILGFIKIGDREWTTEEQNALQAIATLFAQLQARIAAEEQLQYLAE
HHHHHHHHCCCHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDDLSGLLNRRALMAHLGLRLAEGQPGPVSVLFLDLDRLKTVNDYLGHSAGDQFIKMFAE
CCHHHHHHHHHHHHHHHCCEEECCCCCCEEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHH
RLRAGTEKPAVIARVGGDEFVVVPDEPMDVVAVESFARRLQTWLQRRVVIDGEMLARTVS
HHHCCCCCCEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHH
IGVAVGTPGDDTTSDLLRRADQAALSAKSTGGSKTAVFTTEMASQHAIRNDIELHLEGVI
EEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHCCHHHHHHHHH
DEASSALVLHYLPEIDMRTGKVLGTEALVRWRHPTRGLLLPESFIGVAESINLAGKLGRL
HCCCCEEEEEECCCCCCCCCCEECHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VMRSACADFARWRSRRTAGDAILRINVSPVQLVSDGFAATVAGTLDEFGVDGSAVCLEIT
HHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHH
ESVVVQDIEATRHTLAALKEVGVRIAIDDFGTGYSVLTHLKSLPVDTVKIDRSFVRDLGA
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCC
SPGDLAIVRAILALADAFELEVVAEGVETVAAAKTLLELGCPRAQGFMLSRPVDAAAMEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHH
LFREGRIAVDAWRDDAATVNGRQ
HHHCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]