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The map label for this gene is 119870846

Identifier: 119870846

GI number: 119870846

Start: 5047223

End: 5048410

Strand: Direct

Name: 119870846

Synonym: Mkms_4818

Alternate gene names: NA

Gene position: 5047223-5048410 (Clockwise)

Preceding gene: 119870843

Following gene: 119870847

Centisome position: 87.97

GC content: 70.12

Gene sequence:

>1188_bases
ATGCGTACTCCGGTGATCATCGTTGCCGGACAGGGTCAGTCGAACGCGGTGTGTGACGTACTGATGACCGAACCGGGGAC
CGTGGTGGTCAGCCACCGCCTGGACGGGCACGTGGTGGTCCGCACCGTAGCCACCCACCGTCACAAGCGGGTGCTCGTCT
CGGAGTGGCCGTTGGAGCTCCTGAAAGGCTGCGTGGGCTGCACCACCCGTGGCGATCTGCTTGTCTTGCTGCGGAATCTG
CACCGCCGGGAGGACGTCACCCGCATCGTCGTGCAGCTCGCACCCTGGCTCGAACCGGAACCCGTCTGCTGGGCGATCGA
GAACATCGCCGTCCACGTCGGACCCGGCTACATCGACGGTCCGGCGAGTCGTGACGTGGCGATCGATGCCGTGGTGACGA
CCGTGGACACTGCCGTGTGGCTGGCGCAGGCGCTGGGCGACGACGACCTCGACGACAACCGCACGGTCGCACAGGTGGTC
GTGGGCCAGGCCGAGTTCGCCGACGTGCTGGTGCTCACCGAACCGGAACGCAGGACACTGGCCGTGCTGCGCCGGCTGAC
CCCGCGCGCGCGGATCACCGTCGGCACAGACCAGTTCGCCACCGCCGTGCGCAACCTCGAACCCGATGCGCGCCGCGGAC
GCGGCCACAGCCCGCACGATGCGCTGCTGGCCGGCGAACCGCCGCTGCGCGCCGACGGAGACGTGACCATCGTCGAGTTC
AACGCGCGCCGACCGTTTCACCCGCAGCGGCTCCATCGGGCGATCGACGATCTGCTCGACGGCGTGGTGCGCATCCGCGG
GCGGGCGTGGCTGGCCAGCCGGCCCGATGCGGTCGTGTGGATCGAATCGGCCGGTGGCGGTCTGCATGTCGGGCACGCCG
GTGAATGGCTGGCGGCGATGAGCCCGAACCAACGGGCTTACGCCGCACCGGAGCGGGTCGCACTCGCCGCGCTGCACTGG
GACGAGCGCTTCGGCGACCGTCACATCGCCCTGACCCTCTTGGCGTGCGGCGCCGACCCGCAGACCGTGACCGGCGCGCT
GTCGGGCGCGCTGCTGACCGACGACGAGCTGACCCGGCCCGAGACGTGGACGGCGTACGAGGACCCGTTCGGCGACTGGC
ACGAAGACCCGTGCGACCAGGTCGACGAGTCGACGCCCGCGGCTTCGCAACGACACGAAGGAGAGTGA

Upstream 100 bases:

>100_bases
GCATACCCCCCTTATTGAAAATCATTTTCGACAATGCTCGATCGGGACTGTAACGTACGGGTCCAGTTATTGACAATCGT
TCTCAACAAGGGGAGGCGCG

Downstream 100 bases:

>100_bases
CGATGAGACCAGCTCGCGCAACCATCAAGTGGGAGACTCCCGACGGCGTCCGCGTCTACCGCTGACCGTTGCGCCTAAAG
TGGGCGCATGCGTCTGCGAC

Product: cobalamin synthesis CobW domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MRTPVIIVAGQGQSNAVCDVLMTEPGTVVVSHRLDGHVVVRTVATHRHKRVLVSEWPLELLKGCVGCTTRGDLLVLLRNL
HRREDVTRIVVQLAPWLEPEPVCWAIENIAVHVGPGYIDGPASRDVAIDAVVTTVDTAVWLAQALGDDDLDDNRTVAQVV
VGQAEFADVLVLTEPERRTLAVLRRLTPRARITVGTDQFATAVRNLEPDARRGRGHSPHDALLAGEPPLRADGDVTIVEF
NARRPFHPQRLHRAIDDLLDGVVRIRGRAWLASRPDAVVWIESAGGGLHVGHAGEWLAAMSPNQRAYAAPERVALAALHW
DERFGDRHIALTLLACGADPQTVTGALSGALLTDDELTRPETWTAYEDPFGDWHEDPCDQVDESTPAASQRHEGE

Sequences:

>Translated_395_residues
MRTPVIIVAGQGQSNAVCDVLMTEPGTVVVSHRLDGHVVVRTVATHRHKRVLVSEWPLELLKGCVGCTTRGDLLVLLRNL
HRREDVTRIVVQLAPWLEPEPVCWAIENIAVHVGPGYIDGPASRDVAIDAVVTTVDTAVWLAQALGDDDLDDNRTVAQVV
VGQAEFADVLVLTEPERRTLAVLRRLTPRARITVGTDQFATAVRNLEPDARRGRGHSPHDALLAGEPPLRADGDVTIVEF
NARRPFHPQRLHRAIDDLLDGVVRIRGRAWLASRPDAVVWIESAGGGLHVGHAGEWLAAMSPNQRAYAAPERVALAALHW
DERFGDRHIALTLLACGADPQTVTGALSGALLTDDELTRPETWTAYEDPFGDWHEDPCDQVDESTPAASQRHEGE
>Mature_395_residues
MRTPVIIVAGQGQSNAVCDVLMTEPGTVVVSHRLDGHVVVRTVATHRHKRVLVSEWPLELLKGCVGCTTRGDLLVLLRNL
HRREDVTRIVVQLAPWLEPEPVCWAIENIAVHVGPGYIDGPASRDVAIDAVVTTVDTAVWLAQALGDDDLDDNRTVAQVV
VGQAEFADVLVLTEPERRTLAVLRRLTPRARITVGTDQFATAVRNLEPDARRGRGHSPHDALLAGEPPLRADGDVTIVEF
NARRPFHPQRLHRAIDDLLDGVVRIRGRAWLASRPDAVVWIESAGGGLHVGHAGEWLAAMSPNQRAYAAPERVALAALHW
DERFGDRHIALTLLACGADPQTVTGALSGALLTDDELTRPETWTAYEDPFGDWHEDPCDQVDESTPAASQRHEGE

Specific function: Unknown

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 43186; Mature: 43186

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTPVIIVAGQGQSNAVCDVLMTEPGTVVVSHRLDGHVVVRTVATHRHKRVLVSEWPLEL
CCCCEEEEECCCCCCCEEEEEEECCCEEEEEECCCCEEEEEEEHHHHHCEEEHHHCCHHH
LKGCVGCTTRGDLLVLLRNLHRREDVTRIVVQLAPWLEPEPVCWAIENIAVHVGPGYIDG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEECCCCCCC
PASRDVAIDAVVTTVDTAVWLAQALGDDDLDDNRTVAQVVVGQAEFADVLVLTEPERRTL
CCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHCCHHHCEEEEEECCCHHHH
AVLRRLTPRARITVGTDQFATAVRNLEPDARRGRGHSPHDALLAGEPPLRADGDVTIVEF
HHHHHCCCCCEEEECCHHHHHHHHCCCCHHHCCCCCCCCCCEEECCCCCCCCCCEEEEEE
NARRPFHPQRLHRAIDDLLDGVVRIRGRAWLASRPDAVVWIESAGGGLHVGHAGEWLAAM
CCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCCEEEECCCCCCCEEC
SPNQRAYAAPERVALAALHWDERFGDRHIALTLLACGADPQTVTGALSGALLTDDELTRP
CCCCCCCCCCCCEEEEEEEHHHHCCCCEEEEEEEEECCCCHHHHHHHCCCEECCCCCCCC
ETWTAYEDPFGDWHEDPCDQVDESTPAASQRHEGE
CCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRTPVIIVAGQGQSNAVCDVLMTEPGTVVVSHRLDGHVVVRTVATHRHKRVLVSEWPLEL
CCCCEEEEECCCCCCCEEEEEEECCCEEEEEECCCCEEEEEEEHHHHHCEEEHHHCCHHH
LKGCVGCTTRGDLLVLLRNLHRREDVTRIVVQLAPWLEPEPVCWAIENIAVHVGPGYIDG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEECCCCCCC
PASRDVAIDAVVTTVDTAVWLAQALGDDDLDDNRTVAQVVVGQAEFADVLVLTEPERRTL
CCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHCCHHHCEEEEEECCCHHHH
AVLRRLTPRARITVGTDQFATAVRNLEPDARRGRGHSPHDALLAGEPPLRADGDVTIVEF
HHHHHCCCCCEEEECCHHHHHHHHCCCCHHHCCCCCCCCCCEEECCCCCCCCCCEEEEEE
NARRPFHPQRLHRAIDDLLDGVVRIRGRAWLASRPDAVVWIESAGGGLHVGHAGEWLAAM
CCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCCEEEECCCCCCCEEC
SPNQRAYAAPERVALAALHWDERFGDRHIALTLLACGADPQTVTGALSGALLTDDELTRP
CCCCCCCCCCCCEEEEEEEHHHHCCCCEEEEEEEEECCCCHHHHHHHCCCEECCCCCCCC
ETWTAYEDPFGDWHEDPCDQVDESTPAASQRHEGE
CCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]