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The map label for this gene is mauR [H]

Identifier: 119870817

GI number: 119870817

Start: 5022034

End: 5022987

Strand: Direct

Name: mauR [H]

Synonym: Mkms_4789

Alternate gene names: 119870817

Gene position: 5022034-5022987 (Clockwise)

Preceding gene: 119870813

Following gene: 119870824

Centisome position: 87.53

GC content: 70.55

Gene sequence:

>954_bases
ATGGCCAACCGCGCACCATCGATCTGCAAAACTGCAGACATGCCCATTTCATCTCCGCGTCGCCCCAGCGCGGACGATCT
CCTCGTCCTGCTTGCGGTGGGCCGCACCGGCCGGTACACCACGGCCGCGGAGGAACTGGGCCTCAACCACACGACGATCT
CGCGGCGCATCGCAGCCCTGGAGCAGTCCATCGGCGGCCGGCTGGTGGCCCGGGTGGCCGGCGGCTGGGAGCTGACCGAC
CTCGGCCGTGAGGCGCTGGCCGCCGCCGAGGCCGTCGAGTCCGCGGTGCGGTCGCTGAGCGTCGACCCGGCCGGGCGCCG
CGCACTCGAAGGCGTGGTGCGGATCTCGGCGACCGACGGGTTCAGTGCCTACATCGTGGCGCCGGCCGCAGCACTGGTGC
AGCGCGACCATCCCGGCGTCGCGGTCGAGATCGTTGCCACGACCCGGCGGGCGTCACAGCAACGCTCGGGCCTCGACGTG
GAAGTGGTGGTCGGCGAACCGCAGGTGCACCGAGCCGAGGCCATTCGCCTGGGTGACTACTGCCTCGGGTTGTACGGGTC
GCGCGACTATCTGGCCGAACACGGGACGCCGAGCGACGTCGATGACCTCGCCCGGTATCCGCTCGTCTACTTCATCGACT
CGATGCTGCAGGTGGATGACCTCGACTCCGCGACGGGGTTCGCGCCGGCCATGCGGGAGTCGGTGACGTCGACGAACGTC
TTCGTCCATGTGGAGGCCACCCGCGCGGCGGCCGGGTTGGGACTGCTGCCGTGCTTCATGGCGGACCGACACGACGATCT
GGTCCGCGTGCTGCCCAACGCGGTGTCGGTGCGGTTGACCTACTGGCTCGTGACCCGCGCCGAGACCCTGCGCCGACCGG
AGGTCGACGCGGTGGTCGAGGCCATCCGGGCGCGGGTGCACGAACAGCGTGACGTGCTTCTCGGCGCGCCCTGA

Upstream 100 bases:

>100_bases
CTCATCGAGGGCTCCGTTCATGACCGGGGGCATACAGACGGGTGGTGTGTGACTGTCCCCACATGGCTGTGAGTATTCAT
GCACGCCGGACCCGCCCGCA

Downstream 100 bases:

>100_bases
TTCGCGTGGTCGCTGGTCGCCCGGCCGGACGGGGCGCCCGGACAGTTACTTCTTGAACGCATCCTTCACTTTTTCGCCCG
CGTCCTTCAGGCTGGACTTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MANRAPSICKTADMPISSPRRPSADDLLVLLAVGRTGRYTTAAEELGLNHTTISRRIAALEQSIGGRLVARVAGGWELTD
LGREALAAAEAVESAVRSLSVDPAGRRALEGVVRISATDGFSAYIVAPAAALVQRDHPGVAVEIVATTRRASQQRSGLDV
EVVVGEPQVHRAEAIRLGDYCLGLYGSRDYLAEHGTPSDVDDLARYPLVYFIDSMLQVDDLDSATGFAPAMRESVTSTNV
FVHVEATRAAAGLGLLPCFMADRHDDLVRVLPNAVSVRLTYWLVTRAETLRRPEVDAVVEAIRARVHEQRDVLLGAP

Sequences:

>Translated_317_residues
MANRAPSICKTADMPISSPRRPSADDLLVLLAVGRTGRYTTAAEELGLNHTTISRRIAALEQSIGGRLVARVAGGWELTD
LGREALAAAEAVESAVRSLSVDPAGRRALEGVVRISATDGFSAYIVAPAAALVQRDHPGVAVEIVATTRRASQQRSGLDV
EVVVGEPQVHRAEAIRLGDYCLGLYGSRDYLAEHGTPSDVDDLARYPLVYFIDSMLQVDDLDSATGFAPAMRESVTSTNV
FVHVEATRAAAGLGLLPCFMADRHDDLVRVLPNAVSVRLTYWLVTRAETLRRPEVDAVVEAIRARVHEQRDVLLGAP
>Mature_316_residues
ANRAPSICKTADMPISSPRRPSADDLLVLLAVGRTGRYTTAAEELGLNHTTISRRIAALEQSIGGRLVARVAGGWELTDL
GREALAAAEAVESAVRSLSVDPAGRRALEGVVRISATDGFSAYIVAPAAALVQRDHPGVAVEIVATTRRASQQRSGLDVE
VVVGEPQVHRAEAIRLGDYCLGLYGSRDYLAEHGTPSDVDDLARYPLVYFIDSMLQVDDLDSATGFAPAMRESVTSTNVF
VHVEATRAAAGLGLLPCFMADRHDDLVRVLPNAVSVRLTYWLVTRAETLRRPEVDAVVEAIRARVHEQRDVLLGAP

Specific function: Transcriptional activator of the mau genes involved in methylamine metabolism [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081978, Length=187, Percent_Identity=26.7379679144385, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789440, Length=188, Percent_Identity=25, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34069; Mature: 33938

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANRAPSICKTADMPISSPRRPSADDLLVLLAVGRTGRYTTAAEELGLNHTTISRRIAAL
CCCCCCCCHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHH
EQSIGGRLVARVAGGWELTDLGREALAAAEAVESAVRSLSVDPAGRRALEGVVRISATDG
HHHHCCEEEEHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEEEECCC
FSAYIVAPAAALVQRDHPGVAVEIVATTRRASQQRSGLDVEVVVGEPQVHRAEAIRLGDY
CEEEEEHHHHHHHHCCCCCEEEEEEEHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCHH
CLGLYGSRDYLAEHGTPSDVDDLARYPLVYFIDSMLQVDDLDSATGFAPAMRESVTSTNV
HEECCCCHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCEE
FVHVEATRAAAGLGLLPCFMADRHDDLVRVLPNAVSVRLTYWLVTRAETLRRPEVDAVVE
EEEEEEHHHHCCCCHHHHHHCCCCHHHHHHCCCHHEEEEHHHHHHHHHHHCCCCHHHHHH
AIRARVHEQRDVLLGAP
HHHHHHHHHCCEEECCC
>Mature Secondary Structure 
ANRAPSICKTADMPISSPRRPSADDLLVLLAVGRTGRYTTAAEELGLNHTTISRRIAAL
CCCCCCCHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHH
EQSIGGRLVARVAGGWELTDLGREALAAAEAVESAVRSLSVDPAGRRALEGVVRISATDG
HHHHCCEEEEHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEEEECCC
FSAYIVAPAAALVQRDHPGVAVEIVATTRRASQQRSGLDVEVVVGEPQVHRAEAIRLGDY
CEEEEEHHHHHHHHCCCCCEEEEEEEHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCHH
CLGLYGSRDYLAEHGTPSDVDDLARYPLVYFIDSMLQVDDLDSATGFAPAMRESVTSTNV
HEECCCCHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCEE
FVHVEATRAAAGLGLLPCFMADRHDDLVRVLPNAVSVRLTYWLVTRAETLRRPEVDAVVE
EEEEEEHHHHCCCCHHHHHHCCCCHHHHHHCCCHHEEEEHHHHHHHHHHHCCCCHHHHHH
AIRARVHEQRDVLLGAP
HHHHHHHHHCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7957249 [H]