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The map label for this gene is acdA [H]

Identifier: 119870740

GI number: 119870740

Start: 4935011

End: 4936108

Strand: Direct

Name: acdA [H]

Synonym: Mkms_4711

Alternate gene names: 119870740

Gene position: 4935011-4936108 (Clockwise)

Preceding gene: 119870739

Following gene: 119870741

Centisome position: 86.02

GC content: 70.67

Gene sequence:

>1098_bases
ATGGATTTTTCATCGACAGAGGCCGCGAACGACCTCGGCGGCCTGGTCCGCACCATCACCGAGTCGGTGTGCACACCCGA
ACACCAGCGCGAACTCGACACGCTCGAGCATCGCTTCGACCGTGACCTGTGGCGAAAGCTGATCGACGCGGACGTGCTGT
CCACGACGGCGCCGGAGGCGTTGGGCGGCGGCGGGTTCGGAGTGCTCGAGGAGGTCGCGGTGCTCGTGGCTCTGGGTCGC
CAATTGTCCGCGGTCCCGTATCTGGAATCGGTGGTGCTCGCCGCGGGCGCCATATCGACCTTCGGATCCGAACAGCTGCA
GCAGGATTGGGCGGCGCCGGCCGTCGCCGGTGAGAAGGTGCTGACCGTCGCGCTCGAGGGCGAGATGGGGCAGGGCCCGG
TCCAGGCGCAGAGCGACGGCGCGGGCCACCGGTTGACGGGTTCGCGCACGCTCGTGCCGTTCGGCCCGGTCGCCGATGCG
TTCCTGGTGCCCGCCGAATCCGACGGCGGCGTGCAGGTCTTCCTGGTCTCCACCGCGGATGCCGGCGTCGCGGTCGACAC
CCTCGACACGACGGGACACGGCAGCGTCGGGCACCTCGAGCTGTCCGGCGCCGAGGTGGACGCCGCGCGGGTCGTCGGCG
GTGCGGATGTGCTGGCGTGGTTGACCGCTCGCCATGCCCTGGCTCGGGCGGCGTTCCAGCTCGGCGTCCTGGAGCGGGCG
CTCGAGCTGACTGCGACCTACGCCCGCGAGCGCGAGCAGTTCGAACGTCCCATCGGCAGCTTCCAGGCGGTCTCGCAGCG
ACTGGCCGACGGGTACATCGACATCAAGGGACTGCGCCTGACCCTCACCCAGGCGGCCTGGCGGACCTCCGAGGGGCTGC
CCGCCGACATCGACGTGTCGTCCGCGGCGTTCTGGGCGGCCGAGGCCGGACACCGCGTCGCACACACGGCGGTCCATGTG
CACGGCGGTGTGGGCATCGACACCGACCACCCGATCCATCGGTACTTCCTGTCTGCCAAGCAGACCGAGTTCGCGGTCGG
CGGCGCGACGGGACAGTTGCTGCGCATCGGGCGCGAGCTGGCCGACACCCCGGTGTGA

Upstream 100 bases:

>100_bases
GCCTGATCCTGACGTTCGGCGGCGGCACCAACGAGATCCAGCGCGACATCATCGGCATGGTCGCGCTCGGCCTGCCCCGG
GTCAACCGGTAAGGAGCATC

Downstream 100 bases:

>100_bases
CCGTGGGTGCGGATCCGACGGTCGCAAATCTGCTGCGGCCGTTGGCCGATGTCGACGACCGCGGGATCCACGCCGACGGT
GAGTTCGCCAGCTGGCGTGA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MDFSSTEAANDLGGLVRTITESVCTPEHQRELDTLEHRFDRDLWRKLIDADVLSTTAPEALGGGGFGVLEEVAVLVALGR
QLSAVPYLESVVLAAGAISTFGSEQLQQDWAAPAVAGEKVLTVALEGEMGQGPVQAQSDGAGHRLTGSRTLVPFGPVADA
FLVPAESDGGVQVFLVSTADAGVAVDTLDTTGHGSVGHLELSGAEVDAARVVGGADVLAWLTARHALARAAFQLGVLERA
LELTATYAREREQFERPIGSFQAVSQRLADGYIDIKGLRLTLTQAAWRTSEGLPADIDVSSAAFWAAEAGHRVAHTAVHV
HGGVGIDTDHPIHRYFLSAKQTEFAVGGATGQLLRIGRELADTPV

Sequences:

>Translated_365_residues
MDFSSTEAANDLGGLVRTITESVCTPEHQRELDTLEHRFDRDLWRKLIDADVLSTTAPEALGGGGFGVLEEVAVLVALGR
QLSAVPYLESVVLAAGAISTFGSEQLQQDWAAPAVAGEKVLTVALEGEMGQGPVQAQSDGAGHRLTGSRTLVPFGPVADA
FLVPAESDGGVQVFLVSTADAGVAVDTLDTTGHGSVGHLELSGAEVDAARVVGGADVLAWLTARHALARAAFQLGVLERA
LELTATYAREREQFERPIGSFQAVSQRLADGYIDIKGLRLTLTQAAWRTSEGLPADIDVSSAAFWAAEAGHRVAHTAVHV
HGGVGIDTDHPIHRYFLSAKQTEFAVGGATGQLLRIGRELADTPV
>Mature_365_residues
MDFSSTEAANDLGGLVRTITESVCTPEHQRELDTLEHRFDRDLWRKLIDADVLSTTAPEALGGGGFGVLEEVAVLVALGR
QLSAVPYLESVVLAAGAISTFGSEQLQQDWAAPAVAGEKVLTVALEGEMGQGPVQAQSDGAGHRLTGSRTLVPFGPVADA
FLVPAESDGGVQVFLVSTADAGVAVDTLDTTGHGSVGHLELSGAEVDAARVVGGADVLAWLTARHALARAAFQLGVLERA
LELTATYAREREQFERPIGSFQAVSQRLADGYIDIKGLRLTLTQAAWRTSEGLPADIDVSSAAFWAAEAGHRVAHTAVHV
HGGVGIDTDHPIHRYFLSAKQTEFAVGGATGQLLRIGRELADTPV

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=354, Percent_Identity=27.683615819209, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI226958414, Length=348, Percent_Identity=27.2988505747126, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI4557233, Length=383, Percent_Identity=25.8485639686684, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI4501859, Length=343, Percent_Identity=23.6151603498542, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4557231, Length=379, Percent_Identity=23.4828496042216, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI187960098, Length=379, Percent_Identity=23.4828496042216, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87081958, Length=373, Percent_Identity=22.7882037533512, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786223, Length=334, Percent_Identity=23.9520958083832, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=359, Percent_Identity=27.0194986072423, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17508101, Length=373, Percent_Identity=23.8605898123324, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17569725, Length=384, Percent_Identity=23.4375, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17506239, Length=363, Percent_Identity=21.2121212121212, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355753, Length=356, Percent_Identity=27.247191011236, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21356377, Length=341, Percent_Identity=25.5131964809384, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24646207, Length=362, Percent_Identity=26.5193370165746, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24666513, Length=350, Percent_Identity=24.5714285714286, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24660351, Length=133, Percent_Identity=31.5789473684211, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 38326; Mature: 38326

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSSTEAANDLGGLVRTITESVCTPEHQRELDTLEHRFDRDLWRKLIDADVLSTTAPEA
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LGGGGFGVLEEVAVLVALGRQLSAVPYLESVVLAAGAISTFGSEQLQQDWAAPAVAGEKV
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEE
LTVALEGEMGQGPVQAQSDGAGHRLTGSRTLVPFGPVADAFLVPAESDGGVQVFLVSTAD
EEEEEECCCCCCCCCCCCCCCCCEECCCCEEECCCCCCCEEEEECCCCCCEEEEEEEECC
AGVAVDTLDTTGHGSVGHLELSGAEVDAARVVGGADVLAWLTARHALARAAFQLGVLERA
CCEEEEECCCCCCCCEEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LELTATYAREREQFERPIGSFQAVSQRLADGYIDIKGLRLTLTQAAWRTSEGLPADIDVS
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECEEEEEEHHHHHCCCCCCCCCCCC
SAAFWAAEAGHRVAHTAVHVHGGVGIDTDHPIHRYFLSAKQTEFAVGGATGQLLRIGREL
CHHHHHHHCCCEEEEEEEEEECCCCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHH
ADTPV
HCCCC
>Mature Secondary Structure
MDFSSTEAANDLGGLVRTITESVCTPEHQRELDTLEHRFDRDLWRKLIDADVLSTTAPEA
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LGGGGFGVLEEVAVLVALGRQLSAVPYLESVVLAAGAISTFGSEQLQQDWAAPAVAGEKV
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEE
LTVALEGEMGQGPVQAQSDGAGHRLTGSRTLVPFGPVADAFLVPAESDGGVQVFLVSTAD
EEEEEECCCCCCCCCCCCCCCCCEECCCCEEECCCCCCCEEEEECCCCCCEEEEEEEECC
AGVAVDTLDTTGHGSVGHLELSGAEVDAARVVGGADVLAWLTARHALARAAFQLGVLERA
CCEEEEECCCCCCCCEEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LELTATYAREREQFERPIGSFQAVSQRLADGYIDIKGLRLTLTQAAWRTSEGLPADIDVS
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECEEEEEEHHHHHCCCCCCCCCCCC
SAAFWAAEAGHRVAHTAVHVHGGVGIDTDHPIHRYFLSAKQTEFAVGGATGQLLRIGREL
CHHHHHHHCCCEEEEEEEEEECCCCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHH
ADTPV
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]