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The map label for this gene is ucpA [C]

Identifier: 119870704

GI number: 119870704

Start: 4901725

End: 4902513

Strand: Direct

Name: ucpA [C]

Synonym: Mkms_4675

Alternate gene names: 119870704

Gene position: 4901725-4902513 (Clockwise)

Preceding gene: 119870703

Following gene: 119870705

Centisome position: 85.44

GC content: 69.71

Gene sequence:

>789_bases
GTGGCCGAACTGCTCTCGGCGCAGGGTGCCGGGGTGGTGGTCAGCGGACGCAATCCCGACGCGGTCGAACAAGCCGCACA
ACGTGTCTCGGGTGTCGGCTGCGCGGGTTCGCCGGCCGACCCCGAGATTGCCGACGCACTGATCGAACGGTGCGTGAGCG
AGTTCGGGCGCATCGACATCCTCATCAACTGTGCGGGCACCCCCGAGCCGCCGGGGTCGTCGATCCTGAACGTGAGCTCA
GCGCAGTTCCGCGAGCTGCTCGACGCACACCTGGGCACGGTGTTCGAGACGTGCCGAGCCGCGGCCCCGCGGATGGTCGC
GCAGGGCGGCGGGGCGATCGTCAACACGAGTTCGTTTGCCTTCGTTGGCGATTACGGCGGCACCGGGTACCCGGCCGGCA
AGGGCGCGGTCAACGGGCTGACGTCGGCGATCGCCGCGGAACTGAAGGAACACGGCGTGCGGGCGAACGTCGTGTGCCCG
GGCGCCAAGACCCGGCTCTCGAGCGGCGACGAATACGAACAGCACGTCACGGAGTTGAATCGCCGCGGCCTACTCGACGA
CGTGAGCCTGCAGGGAGCCCTGGACGCCGCGCCGCCGGAGTACGTGGCGCCGACATACGCCTACCTGGTCAGCGATCGCG
CGCACGGTGTGACCGGCCGGATCTTCATCGCCGCCGGCGGCTTCGTCGGCGAGTTCGCCCGTCAGTCCCCCGGCTTCCTC
GGCTACCGGGACCACCACGACTCGCCACCGTGGACCGTCGAGGAGTTGCACGAGCTCATCGGGGGCTGA

Upstream 100 bases:

>100_bases
TCGATGACGTTCGAAGAGGCCAAGGGCGATTAGCGAGTCACCGCCGCTGGCCGGCCGCGGCGCAGTCGTCGTCGGCGGTT
CTCGCGGTATCGGCCTCGCG

Downstream 100 bases:

>100_bases
GCGTCGCCGAACGTGAAGCCACTGCGAAAAATCGGGCCGTTCGTCGCACTCAGTTCACGTTCGACGGATGGAGCCCGGCG
GAGCGTCACTATGCTCGGGG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MAELLSAQGAGVVVSGRNPDAVEQAAQRVSGVGCAGSPADPEIADALIERCVSEFGRIDILINCAGTPEPPGSSILNVSS
AQFRELLDAHLGTVFETCRAAAPRMVAQGGGAIVNTSSFAFVGDYGGTGYPAGKGAVNGLTSAIAAELKEHGVRANVVCP
GAKTRLSSGDEYEQHVTELNRRGLLDDVSLQGALDAAPPEYVAPTYAYLVSDRAHGVTGRIFIAAGGFVGEFARQSPGFL
GYRDHHDSPPWTVEELHELIGG

Sequences:

>Translated_262_residues
MAELLSAQGAGVVVSGRNPDAVEQAAQRVSGVGCAGSPADPEIADALIERCVSEFGRIDILINCAGTPEPPGSSILNVSS
AQFRELLDAHLGTVFETCRAAAPRMVAQGGGAIVNTSSFAFVGDYGGTGYPAGKGAVNGLTSAIAAELKEHGVRANVVCP
GAKTRLSSGDEYEQHVTELNRRGLLDDVSLQGALDAAPPEYVAPTYAYLVSDRAHGVTGRIFIAAGGFVGEFARQSPGFL
GYRDHHDSPPWTVEELHELIGG
>Mature_261_residues
AELLSAQGAGVVVSGRNPDAVEQAAQRVSGVGCAGSPADPEIADALIERCVSEFGRIDILINCAGTPEPPGSSILNVSSA
QFRELLDAHLGTVFETCRAAAPRMVAQGGGAIVNTSSFAFVGDYGGTGYPAGKGAVNGLTSAIAAELKEHGVRANVVCPG
AKTRLSSGDEYEQHVTELNRRGLLDDVSLQGALDAAPPEYVAPTYAYLVSDRAHGVTGRIFIAAGGFVGEFARQSPGFLG
YRDHHDSPPWTVEELHELIGG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=238, Percent_Identity=30.2521008403361, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI66933014, Length=189, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI40254992, Length=181, Percent_Identity=29.8342541436464, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI4504505, Length=233, Percent_Identity=24.8927038626609, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI15277342, Length=191, Percent_Identity=31.413612565445, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4758504, Length=177, Percent_Identity=33.8983050847458, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI10190704, Length=241, Percent_Identity=29.045643153527, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI87082100, Length=246, Percent_Identity=30.0813008130081, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=28.4518828451883, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789208, Length=186, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=26.8, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788459, Length=200, Percent_Identity=31, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=27.0833333333333, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786812, Length=199, Percent_Identity=29.6482412060301, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI2367175, Length=242, Percent_Identity=28.5123966942149, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=240, Percent_Identity=30.8333333333333, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17568967, Length=221, Percent_Identity=30.316742081448, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17560676, Length=240, Percent_Identity=27.0833333333333, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=244, Percent_Identity=29.0983606557377, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=172, Percent_Identity=29.0697674418605, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=247, Percent_Identity=27.9352226720648, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=230, Percent_Identity=29.5652173913043, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=26.530612244898, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=26.0162601626016, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=177, Percent_Identity=31.638418079096, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=253, Percent_Identity=29.2490118577075, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=252, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=175, Percent_Identity=29.1428571428571, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=180, Percent_Identity=29.4444444444444, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=178, Percent_Identity=27.5280898876405, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=175, Percent_Identity=30.2857142857143, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=242, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=174, Percent_Identity=29.3103448275862, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=240, Percent_Identity=28.75, Blast_Score=89, Evalue=5e-19,
Organism=Drosophila melanogaster, GI23397609, Length=239, Percent_Identity=29.7071129707113, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357041, Length=235, Percent_Identity=30.2127659574468, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=27.9352226720648, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI18859837, Length=164, Percent_Identity=31.0975609756098, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571526, Length=233, Percent_Identity=29.1845493562232, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644339, Length=228, Percent_Identity=26.7543859649123, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27133; Mature: 27001

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELLSAQGAGVVVSGRNPDAVEQAAQRVSGVGCAGSPADPEIADALIERCVSEFGRIDI
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEE
LINCAGTPEPPGSSILNVSSAQFRELLDAHLGTVFETCRAAAPRMVAQGGGAIVNTSSFA
EEECCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEECCCEE
FVGDYGGTGYPAGKGAVNGLTSAIAAELKEHGVRANVVCPGAKTRLSSGDEYEQHVTELN
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
RRGLLDDVSLQGALDAAPPEYVAPTYAYLVSDRAHGVTGRIFIAAGGFVGEFARQSPGFL
HCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHCCCCCC
GYRDHHDSPPWTVEELHELIGG
CCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
AELLSAQGAGVVVSGRNPDAVEQAAQRVSGVGCAGSPADPEIADALIERCVSEFGRIDI
CCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEE
LINCAGTPEPPGSSILNVSSAQFRELLDAHLGTVFETCRAAAPRMVAQGGGAIVNTSSFA
EEECCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEECCCEE
FVGDYGGTGYPAGKGAVNGLTSAIAAELKEHGVRANVVCPGAKTRLSSGDEYEQHVTELN
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
RRGLLDDVSLQGALDAAPPEYVAPTYAYLVSDRAHGVTGRIFIAAGGFVGEFARQSPGFL
HCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHCCCCCC
GYRDHHDSPPWTVEELHELIGG
CCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9655913; 12597275 [H]