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The map label for this gene is ybdL [H]

Identifier: 119870613

GI number: 119870613

Start: 4815388

End: 4816557

Strand: Direct

Name: ybdL [H]

Synonym: Mkms_4584

Alternate gene names: 119870613

Gene position: 4815388-4816557 (Clockwise)

Preceding gene: 119870612

Following gene: 119870618

Centisome position: 83.93

GC content: 68.97

Gene sequence:

>1170_bases
ATGACGGTGTCCAGACTGCGGCCGTACGCGGTGACGGTGTTCGCCGAGATGTCGGCGCTCGCCGCGCGGATCGGCGCGGT
GAACCTCGGACAGGGATTCCCCGACGAGGACGGTCCGGCGTCGATGCTCGAGGTAGCCCGGCAGGCGATCGCCGACGGCG
TGAACCAGTACCCGCCCGGCCTGGGCATCGCGCCGCTGCGGGAAGCCATTGCCGCGCAACGTAAACGGGTCCACGGCGTC
GACTACGACCCCGACACCGAGGTGCTGGTGACCAACGGCGCCACCGAGGCCATCGCCGCGGCGGTACTCGGTCTCGTCGA
ACCGGGGTCCGAGGTGCTGCTCGTCGAACCGTTCTACGACTCCTACTCCCCGGTGCTCGCGATGGCGGGCTGTCACCGCG
TCGCCGTCCCGATGGTCGAGCACGGCCGCGGCTTCGCGATCGACGTCGACGGTCTGCGCCGGGCGATCACTCCGCGCACC
AGCGCGCTGATCGTCAACAGCCCGCACAACCCGACCGGCATGGTGGCCTCTGACGCCGAACTCGCGGCGATCGCCGAACT
GGCCGTCGAACACGACCTGCTGGTCATCACCGACGAGGTCTACGAACACCTGGTGTTCGACGGATACGAACACCGTCCGC
TGGCCGCCTATCCGGGGATGTCCGGGCGGACCGTCACCATCTCGAGTGCGGCCAAGATGTTCAACGTCACCGGCTGGAAA
ATCGGATGGGCCTGCGGCGCAGCGGATCTCATAGCCGGCGTGCGCGCGGCCAAACAGTACCTCACCTATGTCGGGGGCGC
GCCGTTCCAGCCGGCGGTAGCCCACGCCCTCGACCACGAGGACGCCTGGGTGGCCGCGCTGCGCGACTCCTTCCAGCACA
AGCGCGACCGGCTCGGTTCGGCGCTGGCCGAGTTGGGTTTCGCGGTGCACGACAGTGCGGGCACCTACTTCCTGTGCGCC
GACCCGCGGCCGCTGGGCTATGACGACAGCACCACCTTCTGCGCGGACCTCCCCGAGCGCGCGGGTGTCGCGGCGATCCC
GATGTCGGCGTTCTGCGACCCGCACTCACCGCACATCGACCGGTGGAATCACCTGGTGCGTTTCGCCTTCTGCAAGCGCG
ACGACACCCTGGACGAAGCGATCAGACGGTTGCAGGTGCTGCGCCGGTAG

Upstream 100 bases:

>100_bases
GCTGTGGCAGCGCTACCTCGCGATCATCTTCGACGGGTTGCGACCCGAGGGCGCCCATCCCCTGCCGCAACCGGCGCCGA
ACCTGCCCTAGGCTCGGACC

Downstream 100 bases:

>100_bases
CGCTCACTCGGCGTGGGTCTTGGCCATGACGCGCGCCCGCAGACCCTCCGTCGCCGAGTGCAGCACGATCTTCTTCGCCC
GTTTGACGAGGAACTGCGGG

Product: aminotransferase

Products: N-succinyl-2-L-amino-6-oxoheptanedioate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTVSRLRPYAVTVFAEMSALAARIGAVNLGQGFPDEDGPASMLEVARQAIADGVNQYPPGLGIAPLREAIAAQRKRVHGV
DYDPDTEVLVTNGATEAIAAAVLGLVEPGSEVLLVEPFYDSYSPVLAMAGCHRVAVPMVEHGRGFAIDVDGLRRAITPRT
SALIVNSPHNPTGMVASDAELAAIAELAVEHDLLVITDEVYEHLVFDGYEHRPLAAYPGMSGRTVTISSAAKMFNVTGWK
IGWACGAADLIAGVRAAKQYLTYVGGAPFQPAVAHALDHEDAWVAALRDSFQHKRDRLGSALAELGFAVHDSAGTYFLCA
DPRPLGYDDSTTFCADLPERAGVAAIPMSAFCDPHSPHIDRWNHLVRFAFCKRDDTLDEAIRRLQVLRR

Sequences:

>Translated_389_residues
MTVSRLRPYAVTVFAEMSALAARIGAVNLGQGFPDEDGPASMLEVARQAIADGVNQYPPGLGIAPLREAIAAQRKRVHGV
DYDPDTEVLVTNGATEAIAAAVLGLVEPGSEVLLVEPFYDSYSPVLAMAGCHRVAVPMVEHGRGFAIDVDGLRRAITPRT
SALIVNSPHNPTGMVASDAELAAIAELAVEHDLLVITDEVYEHLVFDGYEHRPLAAYPGMSGRTVTISSAAKMFNVTGWK
IGWACGAADLIAGVRAAKQYLTYVGGAPFQPAVAHALDHEDAWVAALRDSFQHKRDRLGSALAELGFAVHDSAGTYFLCA
DPRPLGYDDSTTFCADLPERAGVAAIPMSAFCDPHSPHIDRWNHLVRFAFCKRDDTLDEAIRRLQVLRR
>Mature_388_residues
TVSRLRPYAVTVFAEMSALAARIGAVNLGQGFPDEDGPASMLEVARQAIADGVNQYPPGLGIAPLREAIAAQRKRVHGVD
YDPDTEVLVTNGATEAIAAAVLGLVEPGSEVLLVEPFYDSYSPVLAMAGCHRVAVPMVEHGRGFAIDVDGLRRAITPRTS
ALIVNSPHNPTGMVASDAELAAIAELAVEHDLLVITDEVYEHLVFDGYEHRPLAAYPGMSGRTVTISSAAKMFNVTGWKI
GWACGAADLIAGVRAAKQYLTYVGGAPFQPAVAHALDHEDAWVAALRDSFQHKRDRLGSALAELGFAVHDSAGTYFLCAD
PRPLGYDDSTTFCADLPERAGVAAIPMSAFCDPHSPHIDRWNHLVRFAFCKRDDTLDEAIRRLQVLRR

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=394, Percent_Identity=35.7868020304569, Blast_Score=248, Evalue=9e-66,
Organism=Homo sapiens, GI56713256, Length=394, Percent_Identity=35.7868020304569, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI95147551, Length=406, Percent_Identity=33.9901477832512, Blast_Score=218, Evalue=6e-57,
Organism=Homo sapiens, GI169881279, Length=406, Percent_Identity=33.9901477832512, Blast_Score=218, Evalue=6e-57,
Organism=Homo sapiens, GI169881281, Length=404, Percent_Identity=29.4554455445545, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI4507369, Length=202, Percent_Identity=28.7128712871287, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI7705897, Length=329, Percent_Identity=25.8358662613982, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI33469970, Length=329, Percent_Identity=25.8358662613982, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1786816, Length=384, Percent_Identity=39.5833333333333, Blast_Score=271, Evalue=4e-74,
Organism=Escherichia coli, GI1788722, Length=394, Percent_Identity=28.6802030456853, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788627, Length=183, Percent_Identity=30.6010928961749, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787710, Length=305, Percent_Identity=27.2131147540984, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787909, Length=256, Percent_Identity=28.125, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71994472, Length=415, Percent_Identity=35.9036144578313, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI71994476, Length=415, Percent_Identity=35.9036144578313, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17567369, Length=415, Percent_Identity=30.1204819277108, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17567663, Length=345, Percent_Identity=26.9565217391304, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6322401, Length=388, Percent_Identity=31.4432989690722, Blast_Score=191, Evalue=1e-49,
Organism=Drosophila melanogaster, GI28573069, Length=405, Percent_Identity=34.320987654321, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24646114, Length=405, Percent_Identity=34.320987654321, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI28573067, Length=405, Percent_Identity=34.320987654321, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI28573065, Length=405, Percent_Identity=34.320987654321, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI18859735, Length=158, Percent_Identity=29.1139240506329, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.17

Molecular weight: Translated: 41837; Mature: 41706

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSRLRPYAVTVFAEMSALAARIGAVNLGQGFPDEDGPASMLEVARQAIADGVNQYPPG
CCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCC
LGIAPLREAIAAQRKRVHGVDYDPDTEVLVTNGATEAIAAAVLGLVEPGSEVLLVEPFYD
CCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCC
SYSPVLAMAGCHRVAVPMVEHGRGFAIDVDGLRRAITPRTSALIVNSPHNPTGMVASDAE
CCCHHHHHHCCHHHCCHHHHCCCCEEEEHHHHHHHCCCCCCEEEEECCCCCCCCEECCHH
LAAIAELAVEHDLLVITDEVYEHLVFDGYEHRPLAAYPGMSGRTVTISSAAKMFNVTGWK
HHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCCCCEECCCCCCCEEEEECHHHHHCCCCEE
IGWACGAADLIAGVRAAKQYLTYVGGAPFQPAVAHALDHEDAWVAALRDSFQHKRDRLGS
EEHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ALAELGFAVHDSAGTYFLCADPRPLGYDDSTTFCADLPERAGVAAIPMSAFCDPHSPHID
HHHHHCCEEECCCCCEEEECCCCCCCCCCCCCEECCCHHHCCEEECCHHHCCCCCCCCHH
RWNHLVRFAFCKRDDTLDEAIRRLQVLRR
HHHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TVSRLRPYAVTVFAEMSALAARIGAVNLGQGFPDEDGPASMLEVARQAIADGVNQYPPG
CCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCC
LGIAPLREAIAAQRKRVHGVDYDPDTEVLVTNGATEAIAAAVLGLVEPGSEVLLVEPFYD
CCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCC
SYSPVLAMAGCHRVAVPMVEHGRGFAIDVDGLRRAITPRTSALIVNSPHNPTGMVASDAE
CCCHHHHHHCCHHHCCHHHHCCCCEEEEHHHHHHHCCCCCCEEEEECCCCCCCCEECCHH
LAAIAELAVEHDLLVITDEVYEHLVFDGYEHRPLAAYPGMSGRTVTISSAAKMFNVTGWK
HHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCCCCEECCCCCCCEEEEECHHHHHCCCCEE
IGWACGAADLIAGVRAAKQYLTYVGGAPFQPAVAHALDHEDAWVAALRDSFQHKRDRLGS
EEHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ALAELGFAVHDSAGTYFLCADPRPLGYDDSTTFCADLPERAGVAAIPMSAFCDPHSPHID
HHHHHCCEEECCCCCEEEECCCCCCCCCCCCCEECCCHHHCCEEECCHHHCCCCCCCCHH
RWNHLVRFAFCKRDDTLDEAIRRLQVLRR
HHHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-L-2,6-diaminoheptanedioate; 2-oxoglutarate

Specific reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]