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The map label for this gene is kcsA [H]

Identifier: 119870563

GI number: 119870563

Start: 4770030

End: 4770812

Strand: Direct

Name: kcsA [H]

Synonym: Mkms_4534

Alternate gene names: 119870563

Gene position: 4770030-4770812 (Clockwise)

Preceding gene: 119870558

Following gene: 119870564

Centisome position: 83.14

GC content: 69.09

Gene sequence:

>783_bases
GTGGGGGTAAGCAGCCGAACCGTGACGACTCCGCAGAACACGATGGAGAAGTGGGAGCGGCGGACGGAGTGGCCCCTGGC
AGGCGTCGCCCTGCTCTTCCTGGCCGCCTACGCCGTTGACGTGCTGATTCGGCCGCACGGCACGGGCGCTGACGTCACCC
GCGCGGTGACGGCGGTGTCGTGGTCGCTGTTCATCGCCGACTACCTGGTGCGGCTCGGCCTGGCCCGCAACCGGTGGCGA
TGGTTCTACCGGCACCTGTTCGACCTGGCCATCGTGGTCCTGCCGCTGCTACGTCCGCTGCAGCTGTTGCGGCTGGTCAC
GCTCATCACCGTGATGCAGCGCGCGGTCGGCAACGCGATCCGCGGCCGGGTGGTCATGTACACCGTCGCCGGTGCGGTGC
TGCTGGTGTTCGTCGCGTCGCTGGCGGTGCTGGAGAGCGAACGCGGGCAACCCGAGGCCCACATCACCCACTTCGGGCAG
GCCCTGTGGTGGTCGATCACCACGATCACCACCGTCGGCTACGGCGATCTGACCCCGGTCACCGCGACGGGACGGGTGAT
CGCGGTGCTGCTGATGATCGGCGGGATCAGCCTCGTCGGGTCGATCACCGCGACGCTGGCGTCGTGGATCGTGCAGCGGG
TGTCCGACGAGGACGCCGCCGCGAACATGGTGACGACCGAACACATCGGCAGGCTGCTCGACGAGATCGCGGATCTGCGC
GGGGAGATCGCACAGATGCGTGAGGAGGGACGGCGATCCGGCGGGCAGCCTCCCCCAGCCTGA

Upstream 100 bases:

>100_bases
GCCGGGCGACCGTTTCGATACTCATGAATTCACCGTAGAACCTCAACAAAAGGTGAGGTCAAATGTTCCCTGGTGAGCGG
CCGCGGTTCGGAGCCCTCGG

Downstream 100 bases:

>100_bases
CCTCTGTATCAGGCAAGATTGCTCCCATGGACAGTGGTGTGGGATCGCCCCGGGTACTGGTCGTCGACGACGACCCCGAC
GTGCTGGCGTCGCTGGAACG

Product: Ion transport 2 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MGVSSRTVTTPQNTMEKWERRTEWPLAGVALLFLAAYAVDVLIRPHGTGADVTRAVTAVSWSLFIADYLVRLGLARNRWR
WFYRHLFDLAIVVLPLLRPLQLLRLVTLITVMQRAVGNAIRGRVVMYTVAGAVLLVFVASLAVLESERGQPEAHITHFGQ
ALWWSITTITTVGYGDLTPVTATGRVIAVLLMIGGISLVGSITATLASWIVQRVSDEDAAANMVTTEHIGRLLDEIADLR
GEIAQMREEGRRSGGQPPPA

Sequences:

>Translated_260_residues
MGVSSRTVTTPQNTMEKWERRTEWPLAGVALLFLAAYAVDVLIRPHGTGADVTRAVTAVSWSLFIADYLVRLGLARNRWR
WFYRHLFDLAIVVLPLLRPLQLLRLVTLITVMQRAVGNAIRGRVVMYTVAGAVLLVFVASLAVLESERGQPEAHITHFGQ
ALWWSITTITTVGYGDLTPVTATGRVIAVLLMIGGISLVGSITATLASWIVQRVSDEDAAANMVTTEHIGRLLDEIADLR
GEIAQMREEGRRSGGQPPPA
>Mature_259_residues
GVSSRTVTTPQNTMEKWERRTEWPLAGVALLFLAAYAVDVLIRPHGTGADVTRAVTAVSWSLFIADYLVRLGLARNRWRW
FYRHLFDLAIVVLPLLRPLQLLRLVTLITVMQRAVGNAIRGRVVMYTVAGAVLLVFVASLAVLESERGQPEAHITHFGQA
LWWSITTITTVGYGDLTPVTATGRVIAVLLMIGGISLVGSITATLASWIVQRVSDEDAAANMVTTEHIGRLLDEIADLRG
EIAQMREEGRRSGGQPPPA

Specific function: Acts as a potassium ion channel [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the potassium channel family [H]

Homologues:

Organism=Homo sapiens, GI5031819, Length=172, Percent_Identity=25.5813953488372, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI25952092, Length=167, Percent_Identity=29.3413173652695, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994134, Length=168, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR003091 [H]

Pfam domain/function: PF07885 Ion_trans_2 [H]

EC number: NA

Molecular weight: Translated: 28506; Mature: 28374

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVSSRTVTTPQNTMEKWERRTEWPLAGVALLFLAAYAVDVLIRPHGTGADVTRAVTAVS
CCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
WSLFIADYLVRLGLARNRWRWFYRHLFDLAIVVLPLLRPLQLLRLVTLITVMQRAVGNAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGRVVMYTVAGAVLLVFVASLAVLESERGQPEAHITHFGQALWWSITTITTVGYGDLTPV
HCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCC
TATGRVIAVLLMIGGISLVGSITATLASWIVQRVSDEDAAANMVTTEHIGRLLDEIADLR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
GEIAQMREEGRRSGGQPPPA
HHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GVSSRTVTTPQNTMEKWERRTEWPLAGVALLFLAAYAVDVLIRPHGTGADVTRAVTAVS
CCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
WSLFIADYLVRLGLARNRWRWFYRHLFDLAIVVLPLLRPLQLLRLVTLITVMQRAVGNAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGRVVMYTVAGAVLLVFVASLAVLESERGQPEAHITHFGQALWWSITTITTVGYGDLTPV
HCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCC
TATGRVIAVLLMIGGISLVGSITATLASWIVQRVSDEDAAANMVTTEHIGRLLDEIADLR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
GEIAQMREEGRRSGGQPPPA
HHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]