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The map label for this gene is IS1086 [H]

Identifier: 119870410

GI number: 119870410

Start: 4600536

End: 4602113

Strand: Direct

Name: IS1086 [H]

Synonym: Mkms_4381

Alternate gene names: 119870410

Gene position: 4600536-4602113 (Clockwise)

Preceding gene: 119870409

Following gene: 119870419

Centisome position: 80.19

GC content: 64.32

Gene sequence:

>1578_bases
TTGAGAGGTTGCGGCGACCGTGTCGTTTCGGAGGACTGTGTCCGGTTTGGGGATCGGCTAGCGCGTTTGTTTAAGGCCGG
GGTGCCGGTGAAGGAGGCGGCGGTCGCTACTGGGGTTTCGCGTGACCGGTGTTATGCGATTCTGCGGGCGATCGGCCGGC
CTGTCGGGCAGGCCCGTGGTCGGGGTGAGCGCGCTGATCAGCGTGGGGTGGCCGACCTGGGTGTGGTCGTGGCCGTATTC
AAGGACACCGGTTCGATCCTGCAGGCGGCCACAGCGTGTGGGGTGTCGCATTCGACGGCACGCAAACTGTTGGTCGCCGA
GGGGCTGGTGACCAGCGGGAAGATCCCGTGGGGCAAGCCCGAGGCGAAACGTCGGTGCTTGGAGCTGTTCGAGCAGGGTT
GGTCCACCGGGGCAGCGGCGCGGGAGGTCGGTGTCAACGTGCGGACCGCGCGGGACTGGCGCAAGGGGATCCGGCACACC
AACAACACGCGGGTTCACCCCGATGGTCGGGTCGTGGACTACACCGACCAGACCGTCTACAAACAGTCGGTGAGCAACCT
GATCTGCGATGACACCGGACGGCCGGCCATCGATGACCGGTATCTGTCGGTCCAGGACCGAGTGGCGATCGCCGATGGCC
TCCTCGGGAAGGAGTCGTTACGGACGATCGCCGGGCGGATCGGCAAAAACGTTTCCACGGTGTCGCGGGAGATTCGTGCG
CGCAGCATTGATGGCCGCTATCTGCCGTATCACGCCGATCGGGCGGCTGCCTCGGCCCGGGCTCGGCCCAAGCAGTCCAA
ACTGGTGGTCAACGTGGTCCTGCGGGGAGCGGTTGAAGAAGGCCTGTCGCGCAAGCTGTCACCGGAGCAGATCTCCAATC
GCCTCCGTCGGGATCATCCCGACGACGAGAGCATGCAGGTGAGCCACGAAACGATCTACCAAGCCCTCTACTTCCAGGCC
CGCGGTGGCCTCAAAAAGGAAGTGCAGCAAGCACTTCGAACCGGGCGCACCCGACGCAAACCACACCGCAAAGAAGGCGA
GCGCTATCAGCGCTTCACCGACCCGATGGTGATGATCAGCGACCGCCCAGCCGAGGTGGACGACCGTGCGGTTCCCGGGC
ATTGGGAAGGGGATTTGATCACCGGGGAGAAGAACCAGACCGCGATCGGCACTCTGGTCGAGCGATCGACGCGCTACACC
ATGCTGGTGCACCTGCCAGGCGGGCACGACGCCGAATCGGTACGGGATGCGCTAATTGCGACTATCAGCACTCTTCCGGC
GCATCTGCGTGGCTCACTGACTTGGGACCAAGGCTGCGAGATGGCAGGGCACAAGCAGTTCACGATGGCCACCGATATGG
CCGTGTACTTCTGCGATCCGGCCAGTCCCTGGCAGCGCGGCAGCAACGAGAACACCAACGGCCTGCTGCGCCAGTACTTC
CCCAAAGGCACCGACCTGAGCATCTACGGACCCGAGGACCTCGAACACGTCGCCCAGGAACTCAACGGCCGCCCACGCAA
AACGCTCGGCTGGGATACCCCAGCCGAGCGCCTGCGTGATCTACTACTGACCAATTAA

Upstream 100 bases:

>100_bases
GGACACCGCGGAGACCACCAGCGCCGACAGACGCTGAACTGCGGAAACGAGACAGCCCCCGGATTTCAGCGGGTTCACAC
GGTCGTCGCAACGCTCTCAT

Downstream 100 bases:

>100_bases
CCAGCAGTGTTGCGACGACCCCTCGAAACCGCCTTTCTCCGGGGGCTGTTCGCTGTCGTGATGGAACTCAGTTCATGTTC
CAGGGTTCGCCGTAGGTGGT

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MRGCGDRVVSEDCVRFGDRLARLFKAGVPVKEAAVATGVSRDRCYAILRAIGRPVGQARGRGERADQRGVADLGVVVAVF
KDTGSILQAATACGVSHSTARKLLVAEGLVTSGKIPWGKPEAKRRCLELFEQGWSTGAAAREVGVNVRTARDWRKGIRHT
NNTRVHPDGRVVDYTDQTVYKQSVSNLICDDTGRPAIDDRYLSVQDRVAIADGLLGKESLRTIAGRIGKNVSTVSREIRA
RSIDGRYLPYHADRAAASARARPKQSKLVVNVVLRGAVEEGLSRKLSPEQISNRLRRDHPDDESMQVSHETIYQALYFQA
RGGLKKEVQQALRTGRTRRKPHRKEGERYQRFTDPMVMISDRPAEVDDRAVPGHWEGDLITGEKNQTAIGTLVERSTRYT
MLVHLPGGHDAESVRDALIATISTLPAHLRGSLTWDQGCEMAGHKQFTMATDMAVYFCDPASPWQRGSNENTNGLLRQYF
PKGTDLSIYGPEDLEHVAQELNGRPRKTLGWDTPAERLRDLLLTN

Sequences:

>Translated_525_residues
MRGCGDRVVSEDCVRFGDRLARLFKAGVPVKEAAVATGVSRDRCYAILRAIGRPVGQARGRGERADQRGVADLGVVVAVF
KDTGSILQAATACGVSHSTARKLLVAEGLVTSGKIPWGKPEAKRRCLELFEQGWSTGAAAREVGVNVRTARDWRKGIRHT
NNTRVHPDGRVVDYTDQTVYKQSVSNLICDDTGRPAIDDRYLSVQDRVAIADGLLGKESLRTIAGRIGKNVSTVSREIRA
RSIDGRYLPYHADRAAASARARPKQSKLVVNVVLRGAVEEGLSRKLSPEQISNRLRRDHPDDESMQVSHETIYQALYFQA
RGGLKKEVQQALRTGRTRRKPHRKEGERYQRFTDPMVMISDRPAEVDDRAVPGHWEGDLITGEKNQTAIGTLVERSTRYT
MLVHLPGGHDAESVRDALIATISTLPAHLRGSLTWDQGCEMAGHKQFTMATDMAVYFCDPASPWQRGSNENTNGLLRQYF
PKGTDLSIYGPEDLEHVAQELNGRPRKTLGWDTPAERLRDLLLTN
>Mature_525_residues
MRGCGDRVVSEDCVRFGDRLARLFKAGVPVKEAAVATGVSRDRCYAILRAIGRPVGQARGRGERADQRGVADLGVVVAVF
KDTGSILQAATACGVSHSTARKLLVAEGLVTSGKIPWGKPEAKRRCLELFEQGWSTGAAAREVGVNVRTARDWRKGIRHT
NNTRVHPDGRVVDYTDQTVYKQSVSNLICDDTGRPAIDDRYLSVQDRVAIADGLLGKESLRTIAGRIGKNVSTVSREIRA
RSIDGRYLPYHADRAAASARARPKQSKLVVNVVLRGAVEEGLSRKLSPEQISNRLRRDHPDDESMQVSHETIYQALYFQA
RGGLKKEVQQALRTGRTRRKPHRKEGERYQRFTDPMVMISDRPAEVDDRAVPGHWEGDLITGEKNQTAIGTLVERSTRYT
MLVHLPGGHDAESVRDALIATISTLPAHLRGSLTWDQGCEMAGHKQFTMATDMAVYFCDPASPWQRGSNENTNGLLRQYF
PKGTDLSIYGPEDLEHVAQELNGRPRKTLGWDTPAERLRDLLLTN

Specific function: Required for the transposition of the insertion element (Potential) [H]

COG id: COG2826

COG function: function code L; Transposase and inactivated derivatives, IS30 family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Escherichia coli, GI1786450, Length=318, Percent_Identity=45.5974842767296, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1790736, Length=318, Percent_Identity=45.2830188679245, Blast_Score=255, Evalue=5e-69,
Organism=Escherichia coli, GI1787671, Length=318, Percent_Identity=45.2830188679245, Blast_Score=255, Evalue=5e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337
- InterPro:   IPR001598 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 58177; Mature: 58177

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS50994 INTEGRASE ; PS01043 TRANSPOSASE_IS30

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGCGDRVVSEDCVRFGDRLARLFKAGVPVKEAAVATGVSRDRCYAILRAIGRPVGQARG
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCC
RGERADQRGVADLGVVVAVFKDTGSILQAATACGVSHSTARKLLVAEGLVTSGKIPWGKP
CCCCHHHCCHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHCCCCCCCCC
EAKRRCLELFEQGWSTGAAAREVGVNVRTARDWRKGIRHTNNTRVHPDGRVVDYTDQTVY
HHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHCCCCCCEECCCCCEEECCHHHHH
KQSVSNLICDDTGRPAIDDRYLSVQDRVAIADGLLGKESLRTIAGRIGKNVSTVSREIRA
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHH
RSIDGRYLPYHADRAAASARARPKQSKLVVNVVLRGAVEEGLSRKLSPEQISNRLRRDHP
HCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
DDESMQVSHETIYQALYFQARGGLKKEVQQALRTGRTRRKPHRKEGERYQRFTDPMVMIS
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEE
DRPAEVDDRAVPGHWEGDLITGEKNQTAIGTLVERSTRYTMLVHLPGGHDAESVRDALIA
CCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHH
TISTLPAHLRGSLTWDQGCEMAGHKQFTMATDMAVYFCDPASPWQRGSNENTNGLLRQYF
HHHHHHHHHCCCCCHHHCCCCCCCCCEEEEECEEEEEECCCCHHHCCCCCCCHHHHHHHC
PKGTDLSIYGPEDLEHVAQELNGRPRKTLGWDTPAERLRDLLLTN
CCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MRGCGDRVVSEDCVRFGDRLARLFKAGVPVKEAAVATGVSRDRCYAILRAIGRPVGQARG
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCC
RGERADQRGVADLGVVVAVFKDTGSILQAATACGVSHSTARKLLVAEGLVTSGKIPWGKP
CCCCHHHCCHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHCCCCCCCCC
EAKRRCLELFEQGWSTGAAAREVGVNVRTARDWRKGIRHTNNTRVHPDGRVVDYTDQTVY
HHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHCCCCCCEECCCCCEEECCHHHHH
KQSVSNLICDDTGRPAIDDRYLSVQDRVAIADGLLGKESLRTIAGRIGKNVSTVSREIRA
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHH
RSIDGRYLPYHADRAAASARARPKQSKLVVNVVLRGAVEEGLSRKLSPEQISNRLRRDHP
HCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
DDESMQVSHETIYQALYFQARGGLKKEVQQALRTGRTRRKPHRKEGERYQRFTDPMVMIS
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEE
DRPAEVDDRAVPGHWEGDLITGEKNQTAIGTLVERSTRYTMLVHLPGGHDAESVRDALIA
CCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHH
TISTLPAHLRGSLTWDQGCEMAGHKQFTMATDMAVYFCDPASPWQRGSNENTNGLLRQYF
HHHHHHHHHCCCCCHHHCCCCCCCCCEEEEECEEEEEECCCCHHHCCCCCCCHHHHHHHC
PKGTDLSIYGPEDLEHVAQELNGRPRKTLGWDTPAERLRDLLLTN
CCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1334071 [H]