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The map label for this gene is ttuB [H]

Identifier: 119870319

GI number: 119870319

Start: 4510357

End: 4511670

Strand: Direct

Name: ttuB [H]

Synonym: Mkms_4289

Alternate gene names: 119870319

Gene position: 4510357-4511670 (Clockwise)

Preceding gene: 119870314

Following gene: 119870320

Centisome position: 78.62

GC content: 65.83

Gene sequence:

>1314_bases
ATGAGCATCGATTCTGTGCTCGCATCGGCGGACGAACTGCACAAGCGCGCCACGCGCAAGGCCGTTCTACGCCTGCTGCC
CGTCATGTGCGCGGTCTACTTCATGGCCTACATCGACCGCACCAACGTCGCGCTCGCGAAAACCCACCTCGAAGCCGACG
TGGGCATCAGCGCCGCGGCATTCGGCTTCGGCGCGGGCATCTTCTTCATCAGCTACGCGTTCCTCGAAGTCCCGAGCAAC
CTGATCATGTATCGCGTCGGGCCGCGGCGGTGGATCGCCCGCATCGCCGTCACGTGGGGCACTTTGTCGGCGCTCATGAT
GTTCGTTCAGGGCGACCTGTCCTTCTACATCATGCGATTCCTGCTCGGCGCCGCCGAGGCCGGCCTTTACCCCGCCCTGA
TGTACATGGTCACGGTCTGGTTCGCGCAGAGCTACCGCGCCACCGTCGTCGGGTTCATCTACCTGGCGCCCACCATCGCG
CTCGTCGTCGGCGGCCCCATGGGCGGCGCGCTGATGGAGCTCGACAGCGCATTCGGCCTGCACGGCTGGCAGTGGATGTT
CCTCATCGAAGGCCTCGTGACCGTCCTCGTCGGCGTCCTGGTGTGGTTCAAGCTTCCCCAGGTACCCAGCGAGGCGCGGT
GGCTGTCCGCCGACGAGGCGCAGATTCTCACCGAACGCGCCGCGGGCGCCCACCACGACACCGCGACCCGGATCCGCGGC
AACGTCAAGGAGGCCTTCGGCCGACCCTTCGTCATCGTGGTCGCGCTGATCTACTTCTTCAACCAGATCACCAACGTCGG
AATCGTTTTCAACATCCCCGCGATCGTCGAGGATCTCGACATCAGCGGTTCGTTCCTCATCGGGCTCCTGTCCGGCAGCG
CGGGAATCGGCGCGACGATCGGCGTGCTGGTGATCCCCCGCCTGTTCGCCCGGTACCCGCGCGAGGCGAGCGCCGTCGGC
ATCCTGGCCGCCGCCACACTGGTCACCTCGATCGCGTTCATGCTCTCCTCCAGTGCGTTGGCCCGCATCCTGCTCATCGC
GATCTCGATGATCTTCGTGTTCGGCACCCTGCCGCTGTTCTGGTCGATCGCGATGGCCCGCATGTCCGGACTGATGGCGG
CGGCCAGCCTGGCGTTCATCAACACCATCGGACTGATCGGCGGGTTCGTCGGGCCCTACCTGTTCGGGCTGGCCGAGACC
GCGACCAACAATCCGTCCGCCGGGTTCTACGTCGTCATCCTCGCCTCGATCATCGGCGTCGCGCTGGCACCGGTGCTCGG
CCACGCCATCAAGCGCGAGGACGCGAGCACGTAA

Upstream 100 bases:

>100_bases
ATAATACTCAGTAGTATCCCTGGTGAGGGCGTTTCACGCCACTCGGTACACGGCAAATCAGCTCTCCCACGCGCGACCGT
GACGCAACCAAAGGAGCCAT

Downstream 100 bases:

>100_bases
AGGCTGAAGCGAGACCGATGACCGCGAAAACTTTTCTGCGACAGGATATCTGCCGACCCACTTGCTGACCGGGCGTGCCC
CCCATATGTTGACGCGGCAC

Product: major facilitator superfamily transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSIDSVLASADELHKRATRKAVLRLLPVMCAVYFMAYIDRTNVALAKTHLEADVGISAAAFGFGAGIFFISYAFLEVPSN
LIMYRVGPRRWIARIAVTWGTLSALMMFVQGDLSFYIMRFLLGAAEAGLYPALMYMVTVWFAQSYRATVVGFIYLAPTIA
LVVGGPMGGALMELDSAFGLHGWQWMFLIEGLVTVLVGVLVWFKLPQVPSEARWLSADEAQILTERAAGAHHDTATRIRG
NVKEAFGRPFVIVVALIYFFNQITNVGIVFNIPAIVEDLDISGSFLIGLLSGSAGIGATIGVLVIPRLFARYPREASAVG
ILAAATLVTSIAFMLSSSALARILLIAISMIFVFGTLPLFWSIAMARMSGLMAAASLAFINTIGLIGGFVGPYLFGLAET
ATNNPSAGFYVVILASIIGVALAPVLGHAIKREDAST

Sequences:

>Translated_437_residues
MSIDSVLASADELHKRATRKAVLRLLPVMCAVYFMAYIDRTNVALAKTHLEADVGISAAAFGFGAGIFFISYAFLEVPSN
LIMYRVGPRRWIARIAVTWGTLSALMMFVQGDLSFYIMRFLLGAAEAGLYPALMYMVTVWFAQSYRATVVGFIYLAPTIA
LVVGGPMGGALMELDSAFGLHGWQWMFLIEGLVTVLVGVLVWFKLPQVPSEARWLSADEAQILTERAAGAHHDTATRIRG
NVKEAFGRPFVIVVALIYFFNQITNVGIVFNIPAIVEDLDISGSFLIGLLSGSAGIGATIGVLVIPRLFARYPREASAVG
ILAAATLVTSIAFMLSSSALARILLIAISMIFVFGTLPLFWSIAMARMSGLMAAASLAFINTIGLIGGFVGPYLFGLAET
ATNNPSAGFYVVILASIIGVALAPVLGHAIKREDAST
>Mature_436_residues
SIDSVLASADELHKRATRKAVLRLLPVMCAVYFMAYIDRTNVALAKTHLEADVGISAAAFGFGAGIFFISYAFLEVPSNL
IMYRVGPRRWIARIAVTWGTLSALMMFVQGDLSFYIMRFLLGAAEAGLYPALMYMVTVWFAQSYRATVVGFIYLAPTIAL
VVGGPMGGALMELDSAFGLHGWQWMFLIEGLVTVLVGVLVWFKLPQVPSEARWLSADEAQILTERAAGAHHDTATRIRGN
VKEAFGRPFVIVVALIYFFNQITNVGIVFNIPAIVEDLDISGSFLIGLLSGSAGIGATIGVLVIPRLFARYPREASAVGI
LAAATLVTSIAFMLSSSALARILLIAISMIFVFGTLPLFWSIAMARMSGLMAAASLAFINTIGLIGGFVGPYLFGLAETA
TNNPSAGFYVVILASIIGVALAPVLGHAIKREDAST

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=404, Percent_Identity=34.9009900990099, Blast_Score=238, Evalue=5e-64,
Organism=Escherichia coli, GI87082320, Length=229, Percent_Identity=26.2008733624454, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1789515, Length=235, Percent_Identity=25.9574468085106, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI2367379, Length=226, Percent_Identity=25.6637168141593, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789152, Length=281, Percent_Identity=23.1316725978648, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321698, Length=224, Percent_Identity=21.4285714285714, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6322612, Length=254, Percent_Identity=24.4094488188976, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323032, Length=245, Percent_Identity=26.530612244898, Blast_Score=73, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6322025, Length=208, Percent_Identity=24.0384615384615, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319876, Length=240, Percent_Identity=21.6666666666667, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319250, Length=201, Percent_Identity=23.3830845771144, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46841; Mature: 46710

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDSVLASADELHKRATRKAVLRLLPVMCAVYFMAYIDRTNVALAKTHLEADVGISAAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHH
FGFGAGIFFISYAFLEVPSNLIMYRVGPRRWIARIAVTWGTLSALMMFVQGDLSFYIMRF
HHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LLGAAEAGLYPALMYMVTVWFAQSYRATVVGFIYLAPTIALVVGGPMGGALMELDSAFGL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
HGWQWMFLIEGLVTVLVGVLVWFKLPQVPSEARWLSADEAQILTERAAGAHHDTATRIRG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHC
NVKEAFGRPFVIVVALIYFFNQITNVGIVFNIPAIVEDLDISGSFLIGLLSGSAGIGATI
CHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECHHHHHHCCCCCHHHHEEECCCCCCHHHH
GVLVIPRLFARYPREASAVGILAAATLVTSIAFMLSSSALARILLIAISMIFVFGTLPLF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WSIAMARMSGLMAAASLAFINTIGLIGGFVGPYLFGLAETATNNPSAGFYVVILASIIGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
ALAPVLGHAIKREDAST
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SIDSVLASADELHKRATRKAVLRLLPVMCAVYFMAYIDRTNVALAKTHLEADVGISAAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHH
FGFGAGIFFISYAFLEVPSNLIMYRVGPRRWIARIAVTWGTLSALMMFVQGDLSFYIMRF
HHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LLGAAEAGLYPALMYMVTVWFAQSYRATVVGFIYLAPTIALVVGGPMGGALMELDSAFGL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
HGWQWMFLIEGLVTVLVGVLVWFKLPQVPSEARWLSADEAQILTERAAGAHHDTATRIRG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHC
NVKEAFGRPFVIVVALIYFFNQITNVGIVFNIPAIVEDLDISGSFLIGLLSGSAGIGATI
CHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECHHHHHHCCCCCHHHHEEECCCCCCHHHH
GVLVIPRLFARYPREASAVGILAAATLVTSIAFMLSSSALARILLIAISMIFVFGTLPLF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WSIAMARMSGLMAAASLAFINTIGLIGGFVGPYLFGLAETATNNPSAGFYVVILASIIGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
ALAPVLGHAIKREDAST
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]