BacMap

Definition	Mycobacterium sp. KMS chromosome, complete genome.
Accession	NC_008705
Length	5,737,227

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The map label for this gene is ydfG [H]

Identifier: 119870191

GI number: 119870191

Start: 4389936

End: 4390739

Strand: Direct

Name: ydfG [H]

Synonym: Mkms_4161

Alternate gene names: 119870191

Gene position: 4389936-4390739 (Clockwise)

Preceding gene: 119870187

Following gene: 119870196

Centisome position: 76.52

GC content: 73.26

Gene sequence:

>804_bases
ATGCTTCCGGCCAGCAGCAGCACCGGGGTGGCGCTCGTCACCGGCGCCTCGTCGGGGATCGGCGAGCAGATCGCCCGCGA
ATTGGCAAGGCGCGGATACGGTTTGGCGCTGGTCGCCCGTCGCGCCGATCAGTTGCGGGCGCTGGTCGACGACCTCGGCT
CGCACGCCCACGCGCTGCCCACCGACCTGTCGCGCCCCGATGAGCGCGCCGCGCTGCCCGCCCGGATCGCCGCACTCGGC
GCCGAGGTCGACATCCTGGTCAACAACGCGGGTATGGCGAACCTCGGCCGCGTCGCCGCATCCGATCCCGCCGCCGAGCT
GACGCTGGTGGAACTCGACGTCGCGGCGGTGGTCGACCTGTGCAGCCGCTTCGTTCCCGGCATGGTCGCGCGCGGCCGCG
GCGCGGTGCTCAACGTCGCCTCGGTCGGCGCGTTCGGCCCGGTGCCGGGGCAGGCCACCTACGGTGCGGCCAAGGCGTTC
GTGCTGTCCTACACCCACGCGTTGCGTGAGGAGTTGCGCGGTACCGGCGTCTCGGCGGCGACCCTGTGTCCCGGACCGGT
CCGTACCGGATTCGGCGAGCAGGCGGGTATCCCCGACGACGAGGCGGAGAAGATGTTGCCGAAGTTCCTGTGGGAGCGGC
CGGACACGGTCGCGAAAGCGGGACTCGACGGGCTGGCCGCGGGCCGGGCGGTCATCGTGCCCGGCACACCGAACCGGGTC
GCCGCGGCGCTCAACCACCTCACGCCGCGGCGCCTGCTGCTGCCGATGCTGGGCCGCGCCCACCCCGGGATGAAGCGCTC
CTAG

Upstream 100 bases:

>100_bases
GAACTGGTCGTCAGGCATCTTGGCCGACATCCACAGGTTCTGGGCGTCGACCGCCGCGAGCCGGCGCGCCGTCATAGCGT
CCGAGGTTAAGCTTCGCCGC

Downstream 100 bases:

>100_bases
CGGGCGGTCCCGATGAAGTCGACGATGTGGCGGCCGACCACGTCGGGCTGTTCGAGCGCCAGGAAGTGCCCGGCGTGCTC
GACGACCGCGACCGCACTCC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MLPASSSTGVALVTGASSGIGEQIARELARRGYGLALVARRADQLRALVDDLGSHAHALPTDLSRPDERAALPARIAALG
AEVDILVNNAGMANLGRVAASDPAAELTLVELDVAAVVDLCSRFVPGMVARGRGAVLNVASVGAFGPVPGQATYGAAKAF
VLSYTHALREELRGTGVSAATLCPGPVRTGFGEQAGIPDDEAEKMLPKFLWERPDTVAKAGLDGLAAGRAVIVPGTPNRV
AAALNHLTPRRLLLPMLGRAHPGMKRS

Sequences:

>Translated_267_residues
MLPASSSTGVALVTGASSGIGEQIARELARRGYGLALVARRADQLRALVDDLGSHAHALPTDLSRPDERAALPARIAALG
AEVDILVNNAGMANLGRVAASDPAAELTLVELDVAAVVDLCSRFVPGMVARGRGAVLNVASVGAFGPVPGQATYGAAKAF
VLSYTHALREELRGTGVSAATLCPGPVRTGFGEQAGIPDDEAEKMLPKFLWERPDTVAKAGLDGLAAGRAVIVPGTPNRV
AAALNHLTPRRLLLPMLGRAHPGMKRS
>Mature_267_residues
MLPASSSTGVALVTGASSGIGEQIARELARRGYGLALVARRADQLRALVDDLGSHAHALPTDLSRPDERAALPARIAALG
AEVDILVNNAGMANLGRVAASDPAAELTLVELDVAAVVDLCSRFVPGMVARGRGAVLNVASVGAFGPVPGQATYGAAKAF
VLSYTHALREELRGTGVSAATLCPGPVRTGFGEQAGIPDDEAEKMLPKFLWERPDTVAKAGLDGLAAGRAVIVPGTPNRV
AAALNHLTPRRLLLPMLGRAHPGMKRS

Specific function: Catalyzes the NADP-dependent oxidation of L-allo- threonine and L-serine [H]

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4557649, Length=185, Percent_Identity=31.8918918918919, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI7705855, Length=188, Percent_Identity=30.8510638297872, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI7706318, Length=214, Percent_Identity=31.3084112149533, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI226371731, Length=188, Percent_Identity=29.7872340425532, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI210032110, Length=249, Percent_Identity=26.5060240963855, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI142976729, Length=194, Percent_Identity=31.9587628865979, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI32483357, Length=200, Percent_Identity=30, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI20149619, Length=199, Percent_Identity=27.1356783919598, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI40254992, Length=198, Percent_Identity=24.7474747474747, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=30.3191489361702, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI5031737, Length=188, Percent_Identity=30.3191489361702, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI109715829, Length=224, Percent_Identity=29.0178571428571, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1787820, Length=218, Percent_Identity=35.3211009174312, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI87082100, Length=189, Percent_Identity=33.8624338624339, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1787335, Length=181, Percent_Identity=32.0441988950276, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786701, Length=185, Percent_Identity=29.1891891891892, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789378, Length=218, Percent_Identity=29.3577981651376, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788459, Length=213, Percent_Identity=30.5164319248826, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=30.4182509505703, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=219, Percent_Identity=30.5936073059361, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=272, Percent_Identity=26.1029411764706, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=29.2490118577075, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=25.5639097744361, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=234, Percent_Identity=30.3418803418803, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=30.9236947791165, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=26.3358778625954, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=241, Percent_Identity=29.045643153527, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=224, Percent_Identity=29.0178571428571, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=27.027027027027, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=26.9230769230769, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17570069, Length=216, Percent_Identity=27.3148148148148, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI212646214, Length=192, Percent_Identity=26.5625, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=218, Percent_Identity=26.1467889908257, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=219, Percent_Identity=27.8538812785388, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25152911, Length=195, Percent_Identity=29.7435897435897, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=208, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=26.5151515151515, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=259, Percent_Identity=25.8687258687259, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=249, Percent_Identity=25.7028112449799, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=191, Percent_Identity=26.7015706806283, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=221, Percent_Identity=27.6018099547511, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=224, Percent_Identity=27.2321428571429, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=193, Percent_Identity=28.4974093264249, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322067, Length=205, Percent_Identity=27.8048780487805, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6319635, Length=179, Percent_Identity=27.3743016759777, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21358495, Length=276, Percent_Identity=28.6231884057971, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=32.6771653543307, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI161076933, Length=187, Percent_Identity=33.1550802139037, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24584748, Length=187, Percent_Identity=33.1550802139037, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24640442, Length=192, Percent_Identity=30.2083333333333, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24580925, Length=197, Percent_Identity=35.0253807106599, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28574402, Length=186, Percent_Identity=31.1827956989247, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24584744, Length=186, Percent_Identity=31.1827956989247, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24584752, Length=193, Percent_Identity=31.0880829015544, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21355631, Length=171, Percent_Identity=32.7485380116959, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28571526, Length=207, Percent_Identity=29.4685990338164, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357041, Length=243, Percent_Identity=30.8641975308642, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=27.1794871794872, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24644339, Length=242, Percent_Identity=28.099173553719, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI116007236, Length=218, Percent_Identity=29.8165137614679, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24641388, Length=226, Percent_Identity=32.7433628318584, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45553409, Length=203, Percent_Identity=25.1231527093596, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24647948, Length=203, Percent_Identity=25.1231527093596, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24647946, Length=203, Percent_Identity=25.1231527093596, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI116007238, Length=176, Percent_Identity=31.25, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24641232, Length=216, Percent_Identity=29.6296296296296, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27466; Mature: 27466

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPASSSTGVALVTGASSGIGEQIARELARRGYGLALVARRADQLRALVDDLGSHAHALP
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
TDLSRPDERAALPARIAALGAEVDILVNNAGMANLGRVAASDPAAELTLVELDVAAVVDL
CCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHCCHHCCCCCCEEEEEHHHHHHHHHH
CSRFVPGMVARGRGAVLNVASVGAFGPVPGQATYGAAKAFVLSYTHALREELRGTGVSAA
HHHHHHHHHHCCCCCEEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TLCPGPVRTGFGEQAGIPDDEAEKMLPKFLWERPDTVAKAGLDGLAAGRAVIVPGTPNRV
EECCCHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCHHHCCCEEEECCCCHHH
AAALNHLTPRRLLLPMLGRAHPGMKRS
HHHHHHCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLPASSSTGVALVTGASSGIGEQIARELARRGYGLALVARRADQLRALVDDLGSHAHALP
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
TDLSRPDERAALPARIAALGAEVDILVNNAGMANLGRVAASDPAAELTLVELDVAAVVDL
CCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHCCHHCCCCCCEEEEEHHHHHHHHHH
CSRFVPGMVARGRGAVLNVASVGAFGPVPGQATYGAAKAFVLSYTHALREELRGTGVSAA
HHHHHHHHHHCCCCCEEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TLCPGPVRTGFGEQAGIPDDEAEKMLPKFLWERPDTVAKAGLDGLAAGRAVIVPGTPNRV
EECCCHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCHHHCCCEEEECCCCHHH
AAALNHLTPRRLLLPMLGRAHPGMKRS
HHHHHHCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]