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The map label for this gene is 119870062

Identifier: 119870062

GI number: 119870062

Start: 4251456

End: 4252712

Strand: Direct

Name: 119870062

Synonym: Mkms_4032

Alternate gene names: NA

Gene position: 4251456-4252712 (Clockwise)

Preceding gene: 119870059

Following gene: 119870064

Centisome position: 74.1

GC content: 70.88

Gene sequence:

>1257_bases
ATGATCGCCAGCAAGCGCGTCCCGCTGTACCTCATCTACTTCTCGGCCTTGACCGCCGGAGCGGGTAACGGCATCTCGCT
GGTCGCCTTCCCCTGGCTGGTGTTGCAGCGCAACGGCTCAGCGGTCGACGCGTCGATCGTCGCGATGGCCGGAACGCTGC
CACTGCTGGTCGCCACGCTGATCGCCGGCGCCGCGGTCGACTACCTGGGCCGGCGCCGGGTGTCGATGATCGCTGATGGT
TTGTCTGCCCTGTCCGTCGCGGCGGTGCCCGTGCTGGCGTGGACGTTCGGCGTGCAGGCGGTCAATGTGGCGGTGCTGGC
CGGACTCGCGGCCCTGGGTGCGTTCTTCGATCCCGCCGGGATGACCGCCCGCGAGACGATGCTGCCCGAGGCCGCGCACC
GGGCCGGGTGGACGCTCGACCACGCCAACAGCGTGTACGAGGCCGTGTTCAACCTGGCCTACATCGTCGGGCCGGGCATC
GGTGGTCTGCTGATCGCGACGATGGGCGGCGTCAACACCATGTGGGTCACGGCCGCGGCGTTCGTCCTGTCGATCGGCGC
CATCGCCGCGCTGCAGCTCGAGGGTGCGGGACGACCCGACCGCGACCAGCTGCCCGAGCGGGTGTGGTCGGGCATCGTGG
AGGGTCTCGGATTCGTCTGGCGCACACCGGTGTTGCGCACCCTGGCGGTGGTGGACCTGGTCGCCACCGGGCTGTACATG
CCGATGGAGAGCGTGCTGTTCCCGAAGTACTTCACCGACCGCGACGAACCCGCGCAGCTGGGCTGGGTCCTGATGGCGCT
GTCGATCGGGGGGCTGGTGGGCGCCCTCGGCTATGCCGCGCTGTCGCGATACGTCAACCGCCGCACGGTGATGCTGGCCG
CCGTGCTCACCCTCGGCGTCGCGATGACCGTCATCGCGTTCCTTCCGCCGCTGCCGGTGATCCTGGTCCTCTCGGCGCTC
GTCGGACTGGTCTACGGGCCGATCGCGCCGATCTACAACTACGTCATGCAGACGCGCGCGCCGGCCCACCTGCGCGGCCG
CGTGGTCGGGGTGATGGGGTCGCTGGCGTATGCAGCGGGCCCGCTCGGCCTGGTGGTGGCGGGTCCACTGGCCGACGGCG
CCGGCCTGTCCGTGACGTTCCTCGCGCTCGCACTGCCGATGCTCGCCCTCGGTGTGGCGGCCGTCTTCCTGCCCGCCCTG
CGCGAACTCGACCGGGAACCGGCCCGACCCCTCAGAGGCGAACCCGGGGCGGGGTGA

Upstream 100 bases:

>100_bases
GCCCGGCGGCACGGGTGAAGAGAAGGGGACGCCGGTGCGCGGGTGAGGTGATTGCACGCCTCCACTGTGCCGCCCGCTGC
TACATTCGGCCGCGATACCC

Downstream 100 bases:

>100_bases
ACACCTCGGCGAGTTGTCGAACCGCTTCGGGGGCGCCGGCGACGTGCAACCTGCCCGCCGCGACCAGTTCGTCGACGCGG
GCGGGGTCGGTGGCGGCGGC

Product: H+ antiporter protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MIASKRVPLYLIYFSALTAGAGNGISLVAFPWLVLQRNGSAVDASIVAMAGTLPLLVATLIAGAAVDYLGRRRVSMIADG
LSALSVAAVPVLAWTFGVQAVNVAVLAGLAALGAFFDPAGMTARETMLPEAAHRAGWTLDHANSVYEAVFNLAYIVGPGI
GGLLIATMGGVNTMWVTAAAFVLSIGAIAALQLEGAGRPDRDQLPERVWSGIVEGLGFVWRTPVLRTLAVVDLVATGLYM
PMESVLFPKYFTDRDEPAQLGWVLMALSIGGLVGALGYAALSRYVNRRTVMLAAVLTLGVAMTVIAFLPPLPVILVLSAL
VGLVYGPIAPIYNYVMQTRAPAHLRGRVVGVMGSLAYAAGPLGLVVAGPLADGAGLSVTFLALALPMLALGVAAVFLPAL
RELDREPARPLRGEPGAG

Sequences:

>Translated_418_residues
MIASKRVPLYLIYFSALTAGAGNGISLVAFPWLVLQRNGSAVDASIVAMAGTLPLLVATLIAGAAVDYLGRRRVSMIADG
LSALSVAAVPVLAWTFGVQAVNVAVLAGLAALGAFFDPAGMTARETMLPEAAHRAGWTLDHANSVYEAVFNLAYIVGPGI
GGLLIATMGGVNTMWVTAAAFVLSIGAIAALQLEGAGRPDRDQLPERVWSGIVEGLGFVWRTPVLRTLAVVDLVATGLYM
PMESVLFPKYFTDRDEPAQLGWVLMALSIGGLVGALGYAALSRYVNRRTVMLAAVLTLGVAMTVIAFLPPLPVILVLSAL
VGLVYGPIAPIYNYVMQTRAPAHLRGRVVGVMGSLAYAAGPLGLVVAGPLADGAGLSVTFLALALPMLALGVAAVFLPAL
RELDREPARPLRGEPGAG
>Mature_418_residues
MIASKRVPLYLIYFSALTAGAGNGISLVAFPWLVLQRNGSAVDASIVAMAGTLPLLVATLIAGAAVDYLGRRRVSMIADG
LSALSVAAVPVLAWTFGVQAVNVAVLAGLAALGAFFDPAGMTARETMLPEAAHRAGWTLDHANSVYEAVFNLAYIVGPGI
GGLLIATMGGVNTMWVTAAAFVLSIGAIAALQLEGAGRPDRDQLPERVWSGIVEGLGFVWRTPVLRTLAVVDLVATGLYM
PMESVLFPKYFTDRDEPAQLGWVLMALSIGGLVGALGYAALSRYVNRRTVMLAAVLTLGVAMTVIAFLPPLPVILVLSAL
VGLVYGPIAPIYNYVMQTRAPAHLRGRVVGVMGSLAYAAGPLGLVVAGPLADGAGLSVTFLALALPMLALGVAAVFLPAL
RELDREPARPLRGEPGAG

Specific function: Could be involved in tetracycline efflux [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43320; Mature: 43320

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIASKRVPLYLIYFSALTAGAGNGISLVAFPWLVLQRNGSAVDASIVAMAGTLPLLVATL
CCCCCCCCEEEHHHHHHHCCCCCCCCHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHH
IAGAAVDYLGRRRVSMIADGLSALSVAAVPVLAWTFGVQAVNVAVLAGLAALGAFFDPAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
MTARETMLPEAAHRAGWTLDHANSVYEAVFNLAYIVGPGIGGLLIATMGGVNTMWVTAAA
CCHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHH
FVLSIGAIAALQLEGAGRPDRDQLPERVWSGIVEGLGFVWRTPVLRTLAVVDLVATGLYM
HHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PMESVLFPKYFTDRDEPAQLGWVLMALSIGGLVGALGYAALSRYVNRRTVMLAAVLTLGV
HHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMTVIAFLPPLPVILVLSALVGLVYGPIAPIYNYVMQTRAPAHLRGRVVGVMGSLAYAAG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
PLGLVVAGPLADGAGLSVTFLALALPMLALGVAAVFLPALRELDREPARPLRGEPGAG
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure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CCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]