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The map label for this gene is fabD [H]

Identifier: 119869458

GI number: 119869458

Start: 3593511

End: 3594455

Strand: Direct

Name: fabD [H]

Synonym: Mkms_3426

Alternate gene names: 119869458

Gene position: 3593511-3594455 (Clockwise)

Preceding gene: 119869457

Following gene: 119869459

Centisome position: 62.63

GC content: 71.64

Gene sequence:

>945_bases
GTGCCTCAATCGCATACCCAGATCGCGCTGCTCGCGCCCGGCCAGGGGTCCCAGACTCCCGGGATGCTCGAGCCGTGGCT
GCAGCTGTCCGGCGCCGCCGAGCGCCTGGCGACGTGGTCGGAGATCAGCGGCCTGGATCTCGCCAGGCTGGGCACCACCG
CCGACGCCGATGAGATCACCGACACCGCGGTGACCCAGCCCCTGGTCGTGGCCGCGACACTGCTCGCCCACGAAGAAGCC
GCCCGACGCGACCTGTTCGGCGGCGCAGGTGACAACACCGTCGTCGCCGGCCACTCGGTCGGGGAGATCGCCGCCTACGC
CATCGCCGGGGTGATCTCCGCCGACGATGCCATCAAGCTGGCCGCGACCCGCGGCGCCGAGATGGCCAAGGCCTGCGCAC
TCGAGCCGACCGGCATGGCCGCCGTCCTCGGTGGTGAGGAGGCCGAGGTCCTTGCCCGCCTCGAGGCGCTGGACCTGGTC
CCCGCCAACCGCAACGCGGCCGGTCAGATCGTGGCCGCCGGTGCGGTGTCCGCCCTGGACAAGCTCGCCGAGGATCCGCC
GGCCAAGGCCCGCGTCCGCAAGCTGGCCACCGCGGGCGCATTCCACACCCGGTACATGGCCTCCGCACTCGACGGCTACG
AAGCCGCCGCCCGCGAGGTGGCCGTCGCCGAACCCACGGCCACGCTGTTGTCGAACGCCGACGGCCAACCGGTAGCCTCG
GCCGCGGACGCGATCGAGAAGCTGGTCGCCCAACTCACCCGGCCGGTGCGCTGGGATCTCTGTACCGCAACGATGCGGCA
GCGCTTCGAGAACGCCGAGAACGCCGCGATCGTCGAATTCCCGCCCGCGGGCACACTCGTCGGCATCGCCAAACGTGAAC
TTCGGGGGGTTCCGACGCACCCCGTCAAGTCCCCCGCTGACCTGGACGGGCTCACCTCGCTGTAA

Upstream 100 bases:

>100_bases
GCATCACATGCCGTTTTGTGGACTTGCTACAAAAACATAAGACGAGGTTCATAATCTCTTACACGGCGCAAAGTCGTCTT
CACAGTGTTCTCTTAGAGAC

Downstream 100 bases:

>100_bases
TCCGCCGGGACAACCACATATCGATCGTCATTCAAGAGTTCTCCGCTCCGCGGAGGCATGTTCACCACATATATAGAAGG
AGCCATCGTGCCCGCCACTC

Product: (acyl-carrier-protein) S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MPQSHTQIALLAPGQGSQTPGMLEPWLQLSGAAERLATWSEISGLDLARLGTTADADEITDTAVTQPLVVAATLLAHEEA
ARRDLFGGAGDNTVVAGHSVGEIAAYAIAGVISADDAIKLAATRGAEMAKACALEPTGMAAVLGGEEAEVLARLEALDLV
PANRNAAGQIVAAGAVSALDKLAEDPPAKARVRKLATAGAFHTRYMASALDGYEAAAREVAVAEPTATLLSNADGQPVAS
AADAIEKLVAQLTRPVRWDLCTATMRQRFENAENAAIVEFPPAGTLVGIAKRELRGVPTHPVKSPADLDGLTSL

Sequences:

>Translated_314_residues
MPQSHTQIALLAPGQGSQTPGMLEPWLQLSGAAERLATWSEISGLDLARLGTTADADEITDTAVTQPLVVAATLLAHEEA
ARRDLFGGAGDNTVVAGHSVGEIAAYAIAGVISADDAIKLAATRGAEMAKACALEPTGMAAVLGGEEAEVLARLEALDLV
PANRNAAGQIVAAGAVSALDKLAEDPPAKARVRKLATAGAFHTRYMASALDGYEAAAREVAVAEPTATLLSNADGQPVAS
AADAIEKLVAQLTRPVRWDLCTATMRQRFENAENAAIVEFPPAGTLVGIAKRELRGVPTHPVKSPADLDGLTSL
>Mature_313_residues
PQSHTQIALLAPGQGSQTPGMLEPWLQLSGAAERLATWSEISGLDLARLGTTADADEITDTAVTQPLVVAATLLAHEEAA
RRDLFGGAGDNTVVAGHSVGEIAAYAIAGVISADDAIKLAATRGAEMAKACALEPTGMAAVLGGEEAEVLARLEALDLVP
ANRNAAGQIVAAGAVSALDKLAEDPPAKARVRKLATAGAFHTRYMASALDGYEAAAREVAVAEPTATLLSNADGQPVASA
ADAIEKLVAQLTRPVRWDLCTATMRQRFENAENAAIVEFPPAGTLVGIAKRELRGVPTHPVKSPADLDGLTSL

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=297, Percent_Identity=28.2828282828283, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1787334, Length=301, Percent_Identity=30.5647840531561, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=29.0102389078498, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24665753, Length=297, Percent_Identity=28.956228956229, Blast_Score=107, Evalue=7e-24,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32247; Mature: 32116

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQSHTQIALLAPGQGSQTPGMLEPWLQLSGAAERLATWSEISGLDLARLGTTADADEIT
CCCCCCEEEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCHHHCCCCCCHHHHH
DTAVTQPLVVAATLLAHEEAARRDLFGGAGDNTVVAGHSVGEIAAYAIAGVISADDAIKL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCEEE
AATRGAEMAKACALEPTGMAAVLGGEEAEVLARLEALDLVPANRNAAGQIVAAGAVSALD
HHHCCHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHH
KLAEDPPAKARVRKLATAGAFHTRYMASALDGYEAAAREVAVAEPTATLLSNADGQPVAS
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHH
AADAIEKLVAQLTRPVRWDLCTATMRQRFENAENAAIVEFPPAGTLVGIAKRELRGVPTH
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCCCCCC
PVKSPADLDGLTSL
CCCCCCCCCCCCCC
>Mature Secondary Structure 
PQSHTQIALLAPGQGSQTPGMLEPWLQLSGAAERLATWSEISGLDLARLGTTADADEIT
CCCCCEEEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCHHHCCCCCCHHHHH
DTAVTQPLVVAATLLAHEEAARRDLFGGAGDNTVVAGHSVGEIAAYAIAGVISADDAIKL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCEEE
AATRGAEMAKACALEPTGMAAVLGGEEAEVLARLEALDLVPANRNAAGQIVAAGAVSALD
HHHCCHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHH
KLAEDPPAKARVRKLATAGAFHTRYMASALDGYEAAAREVAVAEPTATLLSNADGQPVAS
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHH
AADAIEKLVAQLTRPVRWDLCTATMRQRFENAENAAIVEFPPAGTLVGIAKRELRGVPTH
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCCCCCC
PVKSPADLDGLTSL
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA