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The map label for this gene is emrE [C]

Identifier: 119868942

GI number: 119868942

Start: 3051822

End: 3052166

Strand: Direct

Name: emrE [C]

Synonym: Mkms_2910

Alternate gene names: 119868942

Gene position: 3051822-3052166 (Clockwise)

Preceding gene: 119868935

Following gene: 119868943

Centisome position: 53.19

GC content: 70.72

Gene sequence:

>345_bases
GTGCGAAGATCAGTGCTGTTGATCGCAGCCATCGCCACCGAGGTCACCGCCACCCTGGCGCTGCGGGCATCCCACGATGA
TTCGTGGTGGCTGATCGTCGTGGTCGCCGGATATCTCGGGGCGTTCCTGCTCCTCACCGCGGTGCTGCGGGCCGGGATGG
CCGTCGGCGTCGCCTACGGGATCTGGGGGGCATCGGGCACCGCGGCGACCGCGATCCTGGCCGCGGGCATCTTCGGCGAT
CCGTTCACCTGGCCCATTGCCGCCGGCATCGCGCTGATCGTCGGCGGGGTGCTGTTGGTCGAATTCGGCTCGCGCCCGCG
GCCGGAACCCGGTGGCGCGCGGTGA

Upstream 100 bases:

>100_bases
GGGCCTGATGCACCGGTTGATTCGGTCGTCACGAGCAGCACCTCCCTGCGGTAAGCATCGACCCGACCAGGCTACTCACG
CAGTCGGTTAGGTTGGCGCG

Downstream 100 bases:

>100_bases
TGTACCTCGCACTTGCCGCGGCCATCGCGCTGGAGGTGCTCGCGACGCTGTGCCTGCGGGCGTCCGACGGCTTCCGCAAG
AAGGTGTGGATGGCGCCGGT

Product: small multidrug resistance protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: Multidrug Efflux Transporter; Multidrug Resistance Membrane Protein; Integral Membrane Efflux Protein; Small Multidrug Resistance Protein SMR Family; Transporter Small Multidrug Resistance Family Protein; Cation/Cationic Drug Transporter

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MRRSVLLIAAIATEVTATLALRASHDDSWWLIVVVAGYLGAFLLLTAVLRAGMAVGVAYGIWGASGTAATAILAAGIFGD
PFTWPIAAGIALIVGGVLLVEFGSRPRPEPGGAR

Sequences:

>Translated_114_residues
MRRSVLLIAAIATEVTATLALRASHDDSWWLIVVVAGYLGAFLLLTAVLRAGMAVGVAYGIWGASGTAATAILAAGIFGD
PFTWPIAAGIALIVGGVLLVEFGSRPRPEPGGAR
>Mature_114_residues
MRRSVLLIAAIATEVTATLALRASHDDSWWLIVVVAGYLGAFLLLTAVLRAGMAVGVAYGIWGASGTAATAILAAGIFGD
PFTWPIAAGIALIVGGVLLVEFGSRPRPEPGGAR

Specific function: Multidrug Transporter. Confers Resistance To A Wide Range Of Toxic Compounds By Removing Them For The Cells. The Efflux Is Coupled To An Influx Of Protons. Probably Prevents The Incorporation Of Methyl VIologen Into Cells. Involved In Ethidium Bromide Ef

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 11645; Mature: 11645

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSVLLIAAIATEVTATLALRASHDDSWWLIVVVAGYLGAFLLLTAVLRAGMAVGVAYG
CCCHHHHHHHHHHHHHHHHHEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IWGASGTAATAILAAGIFGDPFTWPIAAGIALIVGGVLLVEFGSRPRPEPGGAR
CCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRRSVLLIAAIATEVTATLALRASHDDSWWLIVVVAGYLGAFLLLTAVLRAGMAVGVAYG
CCCHHHHHHHHHHHHHHHHHEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IWGASGTAATAILAAGIFGDPFTWPIAAGIALIVGGVLLVEFGSRPRPEPGGAR
CCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA