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The map label for this gene is glcB [H]

Identifier: 119868893

GI number: 119868893

Start: 2981438

End: 2983633

Strand: Direct

Name: glcB [H]

Synonym: Mkms_2861

Alternate gene names: 119868893

Gene position: 2981438-2983633 (Clockwise)

Preceding gene: 119868892

Following gene: 119868894

Centisome position: 51.97

GC content: 66.39

Gene sequence:

>2196_bases
ATGACTGATCGCGTGACGGTGGGAAACCTGCGCGTGGCCCGCGCGCTCTACGACTTCATCACCGATGAGGCGCTGGCCGG
TACCGATCTCGACCCGGACAGCTTCTGGTCGGGTGTCGACAAGGTCGTCGCCGACCTGACCCCGCGCAACCAGGAACTGC
TCGCCCGCCGCGACGACCTGCAGGCGCAGATCGACAAGTGGCACCGGCAGCGGGCGATCGGTCCGCACGACGCCGACGAG
TACAAGCAGTTCCTCACCGAGATCGGCTACCTCGAACCCGATCCGGGTGACTTCACGATCACCACCGCAGGCGTCGACGA
CGAAATCACCACGACCGCAGGCCCGCAGTTGGTGGTGCCGGTGCTCAACGCCCGCTTCGCGCTCAACGCGGCCAACGCGC
GGTGGGGTTCGCTCTATGACGCGCTGTACGGCACCGACGTCATCAGCGAGGAGGACGGCGCCGAGAAGGGCACCAGCTAC
AACCGCGTCCGTGGCGACAAGGTGATCGCCTACGCGCGCGAATTCCTCGACGGCGCAGCGCCGTTGGCGTCCGGCTCCTA
TGCCGACGCCACCGGTTTCCGAATCGAGGACGGGCAGGTGCAGGTCGAGCTCGGAGACGACCAGTGGGTCGGTCTGGCCG
ACCCGGACCAGTTTGTCGGCTACACCGGTGAACTCGGATCCCCGCAGTGGTCGATCCTGCTGCGCAACAACGGACTGCAC
ATCGAGATCCTCATCGACCCCGACTCGCCCGTCGGCTCGACCGACAAGGCCGGCGTCAAGGACGTCGTGCTCGAATCCGC
CGTCACCACCATCATGGATTTCGAGGATTCGGTCGCCGCGGTCGACGCCGAGGACAAGGTGCTGGGCTACCGCAACTGGC
TGGGGCTCAACCGCGGCGACCTGAGCGAAGAGGTCAGCAAGGGCGACAAGACCTTCACCCGCGTGCTCAACCCCGACCGC
ACGTACACCACCCCGGACGGTTCCGGCGAGCTCACCCTGCCCGGCCGCAGCCTGCTGTTCGTGCGCAACGTCGGACATCT
GATGACCAACGACGCGATCACGGACGCCGAGGGTAACGAGGTGTTCGAAGGTATCCAGGACGCCCTGTTCACCGGTCTGA
TCGCCATGCACGGTCTCAAGGAGAGTGACGCGAACGGCCCGCTGCGCAACAGCCGCACGGGTTCGGTCTACATCGTCAAG
CCCAAGATGCACGGCCCCGCCGAGGTGGCCTACACCGTCGACCTGTTCAGCCGCGTCGAGGACGTCCTGGGGCTGCCGCA
GAACACCCTCAAGGTCGGCATCATGGACGAGGAACGCCGCACCACCCTGAACCTCAAGGCGTGCATCAAGGCCGCCGCCG
ACCGGGTGGTGTTCATCAACACCGGGTTCCTGGACCGCACCGGCGACGAGATCCACACCTCGATGGAGGCGGGTCCGATG
ATCCGCAAGGGCGCGATGAAGAGTCAGCCGTGGATCAAGGCCTACGAGGACCAGAACGTCGACGTGGGTCTGGCCACCGG
TTTCTCGGGCCGGGCCCAGATCGGCAAGGGTATGTGGGCGATGACGGACCTGATGGCCGACATGGTCGAACAGAAGATCG
GTCAGCCGAAGGCCGGCGCCACCACCGCATGGGTGCCGTCGCCGACCGCGGCCACGCTGCACGCCATGCACTACCACCAG
GTCGACGTGTACGCCGTCCACAAGGAACTCGAGGGCAAGCAGCGCGCATCGCTCGACGATCTGCTCACCATCCCGCTGGC
CAAGGAACTGGCCTGGGCGCCCGAGGAGATCCGCGAGGAGGTCGACAACAACTGCCAGTCGATCCTGGGCTACGTCGTCC
GCTGGATCGACGCCGGTGTCGGTTGTTCCAAGGTGCCCGACATCCACGACATCGCGCTGATGGAGGATCGCGCCACGCTG
CGGATCTCCAGCCAGCTGCTGGCCAACTGGCTGCGCCACGGCGTCATCACCGAAGAGGACGTCAAGACCAGCCTGCGCCG
GATGGCCGCGGTGGTCGACGAGCAGAACGCCAAGGACCCGGACTTCAAGCCGATGGCAACCGACCCGGACTCCAGCATCG
CCTTCCAGGCCGCGCAGGAACTCATCCTCGCGGGCGGCACGCAGCCCAGCGGGTACACCGAGCCGATCCTGCACCGACGC
CGACGCGAGTACAAAGCCAGCGTTGCCGGCGCCTGA

Upstream 100 bases:

>100_bases
CATCGGTGCATGCTGGATTCGTCGCTGTTACCGATGGGTAAGCTGGATCGACGGCGGCGTGCCGGGTGGCGCGCGTGAAG
TACGGCCGAGGAGGAAGACG

Downstream 100 bases:

>100_bases
GGCGGTCCTGGCGGACGACTAGACTGCCCGGGGCGCGGACGAAAGCGGCGATGACCCAGCGATGATCAAGCGACGACGCG
AACACGGGGACCGGAATGGG

Product: malate synthase G

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 731; Mature: 730

Protein sequence:

>731_residues
MTDRVTVGNLRVARALYDFITDEALAGTDLDPDSFWSGVDKVVADLTPRNQELLARRDDLQAQIDKWHRQRAIGPHDADE
YKQFLTEIGYLEPDPGDFTITTAGVDDEITTTAGPQLVVPVLNARFALNAANARWGSLYDALYGTDVISEEDGAEKGTSY
NRVRGDKVIAYAREFLDGAAPLASGSYADATGFRIEDGQVQVELGDDQWVGLADPDQFVGYTGELGSPQWSILLRNNGLH
IEILIDPDSPVGSTDKAGVKDVVLESAVTTIMDFEDSVAAVDAEDKVLGYRNWLGLNRGDLSEEVSKGDKTFTRVLNPDR
TYTTPDGSGELTLPGRSLLFVRNVGHLMTNDAITDAEGNEVFEGIQDALFTGLIAMHGLKESDANGPLRNSRTGSVYIVK
PKMHGPAEVAYTVDLFSRVEDVLGLPQNTLKVGIMDEERRTTLNLKACIKAAADRVVFINTGFLDRTGDEIHTSMEAGPM
IRKGAMKSQPWIKAYEDQNVDVGLATGFSGRAQIGKGMWAMTDLMADMVEQKIGQPKAGATTAWVPSPTAATLHAMHYHQ
VDVYAVHKELEGKQRASLDDLLTIPLAKELAWAPEEIREEVDNNCQSILGYVVRWIDAGVGCSKVPDIHDIALMEDRATL
RISSQLLANWLRHGVITEEDVKTSLRRMAAVVDEQNAKDPDFKPMATDPDSSIAFQAAQELILAGGTQPSGYTEPILHRR
RREYKASVAGA

Sequences:

>Translated_731_residues
MTDRVTVGNLRVARALYDFITDEALAGTDLDPDSFWSGVDKVVADLTPRNQELLARRDDLQAQIDKWHRQRAIGPHDADE
YKQFLTEIGYLEPDPGDFTITTAGVDDEITTTAGPQLVVPVLNARFALNAANARWGSLYDALYGTDVISEEDGAEKGTSY
NRVRGDKVIAYAREFLDGAAPLASGSYADATGFRIEDGQVQVELGDDQWVGLADPDQFVGYTGELGSPQWSILLRNNGLH
IEILIDPDSPVGSTDKAGVKDVVLESAVTTIMDFEDSVAAVDAEDKVLGYRNWLGLNRGDLSEEVSKGDKTFTRVLNPDR
TYTTPDGSGELTLPGRSLLFVRNVGHLMTNDAITDAEGNEVFEGIQDALFTGLIAMHGLKESDANGPLRNSRTGSVYIVK
PKMHGPAEVAYTVDLFSRVEDVLGLPQNTLKVGIMDEERRTTLNLKACIKAAADRVVFINTGFLDRTGDEIHTSMEAGPM
IRKGAMKSQPWIKAYEDQNVDVGLATGFSGRAQIGKGMWAMTDLMADMVEQKIGQPKAGATTAWVPSPTAATLHAMHYHQ
VDVYAVHKELEGKQRASLDDLLTIPLAKELAWAPEEIREEVDNNCQSILGYVVRWIDAGVGCSKVPDIHDIALMEDRATL
RISSQLLANWLRHGVITEEDVKTSLRRMAAVVDEQNAKDPDFKPMATDPDSSIAFQAAQELILAGGTQPSGYTEPILHRR
RREYKASVAGA
>Mature_730_residues
TDRVTVGNLRVARALYDFITDEALAGTDLDPDSFWSGVDKVVADLTPRNQELLARRDDLQAQIDKWHRQRAIGPHDADEY
KQFLTEIGYLEPDPGDFTITTAGVDDEITTTAGPQLVVPVLNARFALNAANARWGSLYDALYGTDVISEEDGAEKGTSYN
RVRGDKVIAYAREFLDGAAPLASGSYADATGFRIEDGQVQVELGDDQWVGLADPDQFVGYTGELGSPQWSILLRNNGLHI
EILIDPDSPVGSTDKAGVKDVVLESAVTTIMDFEDSVAAVDAEDKVLGYRNWLGLNRGDLSEEVSKGDKTFTRVLNPDRT
YTTPDGSGELTLPGRSLLFVRNVGHLMTNDAITDAEGNEVFEGIQDALFTGLIAMHGLKESDANGPLRNSRTGSVYIVKP
KMHGPAEVAYTVDLFSRVEDVLGLPQNTLKVGIMDEERRTTLNLKACIKAAADRVVFINTGFLDRTGDEIHTSMEAGPMI
RKGAMKSQPWIKAYEDQNVDVGLATGFSGRAQIGKGMWAMTDLMADMVEQKIGQPKAGATTAWVPSPTAATLHAMHYHQV
DVYAVHKELEGKQRASLDDLLTIPLAKELAWAPEEIREEVDNNCQSILGYVVRWIDAGVGCSKVPDIHDIALMEDRATLR
ISSQLLANWLRHGVITEEDVKTSLRRMAAVVDEQNAKDPDFKPMATDPDSSIAFQAAQELILAGGTQPSGYTEPILHRRR
REYKASVAGA

Specific function: Accounts For Almost The Entire Malate-Synthesizing Activity In Cells Metabolizing Glyoxylate. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family. GlcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789348, Length=732, Percent_Identity=57.2404371584699, Blast_Score=850, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR001465
- InterPro:   IPR006253 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 79921; Mature: 79790

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRVTVGNLRVARALYDFITDEALAGTDLDPDSFWSGVDKVVADLTPRNQELLARRDDL
CCCCEEECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
QAQIDKWHRQRAIGPHDADEYKQFLTEIGYLEPDPGDFTITTAGVDDEITTTAGPQLVVP
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEE
VLNARFALNAANARWGSLYDALYGTDVISEEDGAEKGTSYNRVRGDKVIAYAREFLDGAA
ECCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHCCCC
PLASGSYADATGFRIEDGQVQVELGDDQWVGLADPDQFVGYTGELGSPQWSILLRNNGLH
CCCCCCCCCCCCEEEECCEEEEEECCCCEECCCCCHHHCCCCCCCCCCCEEEEEECCCEE
IEILIDPDSPVGSTDKAGVKDVVLESAVTTIMDFEDSVAAVDAEDKVLGYRNWLGLNRGD
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHCCCCCCC
LSEEVSKGDKTFTRVLNPDRTYTTPDGSGELTLPGRSLLFVRNVGHLMTNDAITDAEGNE
HHHHHHCCHHHHHHHCCCCCCEECCCCCCEEEECCCCEEEEEHHHHHHCCCCCCCCCCHH
VFEGIQDALFTGLIAMHGLKESDANGPLRNSRTGSVYIVKPKMHGPAEVAYTVDLFSRVE
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
DVLGLPQNTLKVGIMDEERRTTLNLKACIKAAADRVVFINTGFLDRTGDEIHTSMEAGPM
HHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHCCCH
IRKGAMKSQPWIKAYEDQNVDVGLATGFSGRAQIGKGMWAMTDLMADMVEQKIGQPKAGA
HHHCCCCCCCCEEECCCCCCEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCC
TTAWVPSPTAATLHAMHYHQVDVYAVHKELEGKQRASLDDLLTIPLAKELAWAPEEIREE
EEEECCCCCHHHHHHHHHHEEEEEEEHHHHCCHHHCCHHHHHCCHHHHHHCCCHHHHHHH
VDNNCQSILGYVVRWIDAGVGCSKVPDIHDIALMEDRATLRISSQLLANWLRHGVITEED
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEECCCHHEEHHHHHHHHHHHCCCCCHHH
VKTSLRRMAAVVDEQNAKDPDFKPMATDPDSSIAFQAAQELILAGGTQPSGYTEPILHRR
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
RREYKASVAGA
HHHHHHHCCCC
>Mature Secondary Structure 
TDRVTVGNLRVARALYDFITDEALAGTDLDPDSFWSGVDKVVADLTPRNQELLARRDDL
CCCEEECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
QAQIDKWHRQRAIGPHDADEYKQFLTEIGYLEPDPGDFTITTAGVDDEITTTAGPQLVVP
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEE
VLNARFALNAANARWGSLYDALYGTDVISEEDGAEKGTSYNRVRGDKVIAYAREFLDGAA
ECCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHCCCC
PLASGSYADATGFRIEDGQVQVELGDDQWVGLADPDQFVGYTGELGSPQWSILLRNNGLH
CCCCCCCCCCCCEEEECCEEEEEECCCCEECCCCCHHHCCCCCCCCCCCEEEEEECCCEE
IEILIDPDSPVGSTDKAGVKDVVLESAVTTIMDFEDSVAAVDAEDKVLGYRNWLGLNRGD
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHCCCCCCC
LSEEVSKGDKTFTRVLNPDRTYTTPDGSGELTLPGRSLLFVRNVGHLMTNDAITDAEGNE
HHHHHHCCHHHHHHHCCCCCCEECCCCCCEEEECCCCEEEEEHHHHHHCCCCCCCCCCHH
VFEGIQDALFTGLIAMHGLKESDANGPLRNSRTGSVYIVKPKMHGPAEVAYTVDLFSRVE
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
DVLGLPQNTLKVGIMDEERRTTLNLKACIKAAADRVVFINTGFLDRTGDEIHTSMEAGPM
HHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHCCCH
IRKGAMKSQPWIKAYEDQNVDVGLATGFSGRAQIGKGMWAMTDLMADMVEQKIGQPKAGA
HHHCCCCCCCCEEECCCCCCEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCC
TTAWVPSPTAATLHAMHYHQVDVYAVHKELEGKQRASLDDLLTIPLAKELAWAPEEIREE
EEEECCCCCHHHHHHHHHHEEEEEEEHHHHCCHHHCCHHHHHCCHHHHHHCCCHHHHHHH
VDNNCQSILGYVVRWIDAGVGCSKVPDIHDIALMEDRATLRISSQLLANWLRHGVITEED
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEECCCHHEEHHHHHHHHHHHCCCCCHHH
VKTSLRRMAAVVDEQNAKDPDFKPMATDPDSSIAFQAAQELILAGGTQPSGYTEPILHRR
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
RREYKASVAGA
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA