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The map label for this gene is fbpC [H]

Identifier: 119868849

GI number: 119868849

Start: 2936977

End: 2937981

Strand: Direct

Name: fbpC [H]

Synonym: Mkms_2817

Alternate gene names: 119868849

Gene position: 2936977-2937981 (Clockwise)

Preceding gene: 119868847

Following gene: 119868850

Centisome position: 51.19

GC content: 65.67

Gene sequence:

>1005_bases
ATGAAATTCGTCGGAAAGTTCCGCGATACAGCGAGGCGGACATGGAGGCGGATGGCGGTGGTTGCGGTCGCCGCGATCAC
GCTTCCGGGTCTGATCGGCTTCGCTGGGGGTTCGGCGACCGCAGGTGCCTTCTCGAGGCCGGGTCTGCCGGTCGAGTACC
TCGACGTGTTCTCCCAGTCCATGAACCGCAACATCCGCATCCAGTTCCAGGGCGGCGGACCGCACGCGGTCTACCTGCTC
GACGGGTTGCGGGCGCAGGACGACTACAACGGCTGGGACATCAACACCCCGGCGTTCGAGTGGTACCACCAGTCGGGCCT
GTCGGTGGTCATGCCCGTCGGCGGCCAGTCCAGCTTCTACACCGACTGGTACCAGCCGTCGCGCGGCAACGGTCAGGACT
ACACCTACAAATGGGAGACGTTCCTGACCCAGGAGCTGCCCGCGTGGCTCGAGGCCAACCGCGGCGTGTCGCCCAGCGGC
AATGCGGTCGTGGGTATCTCGATGGCGGGCAGCACCGCGCTCACCTACTCGATCTACTACCCGCAGAAGTTCGTCTACGC
GGCGTCGTTGTCGGGCTTCCTCAACCCCTCCGAGGGCTGGTGGCCGATGCTGATCGGGCTGGCGATGCAGGACTCCGGCA
AGTACAACGCCGAGAGCATGTGGGGCCCGGCCAGCGATCCGGCGTGGCGGCGTAACGACCCGATGGTCAACATCAACCAG
CTGGTCGCCAACAACACCCGGGTGTGGATCTACTGCGGTACCGGCACACCGTCGGAACTCGACGCCGGCACCTCCGGTGG
CAACCTCATGGCGGCCCAGTTCCTCGAGGGCTTCACGTTGCGCACCAACGTCACCTTCCGCGACAACTACATCGCCGCGG
GCGGAACCAACGGGGTCTTCAACTTCCCGTCGAACGGCACACATGCCTGGGGCTACTGGGGTCAGCAGCTGCAGCAGATG
AAGCCGGACATCCAGCGGGTGCTCGGCGCCCAGGGCGCCATCTAG

Upstream 100 bases:

>100_bases
GTGTTGGTGCGCCTGTGACGGATGGGGCGCGTGTTTCATGAGTCTCGATAAGCGACGGCACTGCTTGTGGCATGCGAAGA
AAGGTGGGTGGGTTGCCGTT

Downstream 100 bases:

>100_bases
ATCCACCCACAACCAGGGAGCCTGCCGCCACCCCCCAGGCGGCAGGCTCCCTGCCGTTTGCGGCAAACTCCGCCCGGGGT
GACCGGAGGCGACCTTAGAG

Product: putative esterase

Products: NA

Alternate protein names: Antigen 85 complex C; 85C; Ag85C; Fibronectin-binding protein C; Mycolyl transferase 85C [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKFVGKFRDTARRTWRRMAVVAVAAITLPGLIGFAGGSATAGAFSRPGLPVEYLDVFSQSMNRNIRIQFQGGGPHAVYLL
DGLRAQDDYNGWDINTPAFEWYHQSGLSVVMPVGGQSSFYTDWYQPSRGNGQDYTYKWETFLTQELPAWLEANRGVSPSG
NAVVGISMAGSTALTYSIYYPQKFVYAASLSGFLNPSEGWWPMLIGLAMQDSGKYNAESMWGPASDPAWRRNDPMVNINQ
LVANNTRVWIYCGTGTPSELDAGTSGGNLMAAQFLEGFTLRTNVTFRDNYIAAGGTNGVFNFPSNGTHAWGYWGQQLQQM
KPDIQRVLGAQGAI

Sequences:

>Translated_334_residues
MKFVGKFRDTARRTWRRMAVVAVAAITLPGLIGFAGGSATAGAFSRPGLPVEYLDVFSQSMNRNIRIQFQGGGPHAVYLL
DGLRAQDDYNGWDINTPAFEWYHQSGLSVVMPVGGQSSFYTDWYQPSRGNGQDYTYKWETFLTQELPAWLEANRGVSPSG
NAVVGISMAGSTALTYSIYYPQKFVYAASLSGFLNPSEGWWPMLIGLAMQDSGKYNAESMWGPASDPAWRRNDPMVNINQ
LVANNTRVWIYCGTGTPSELDAGTSGGNLMAAQFLEGFTLRTNVTFRDNYIAAGGTNGVFNFPSNGTHAWGYWGQQLQQM
KPDIQRVLGAQGAI
>Mature_334_residues
MKFVGKFRDTARRTWRRMAVVAVAAITLPGLIGFAGGSATAGAFSRPGLPVEYLDVFSQSMNRNIRIQFQGGGPHAVYLL
DGLRAQDDYNGWDINTPAFEWYHQSGLSVVMPVGGQSSFYTDWYQPSRGNGQDYTYKWETFLTQELPAWLEANRGVSPSG
NAVVGISMAGSTALTYSIYYPQKFVYAASLSGFLNPSEGWWPMLIGLAMQDSGKYNAESMWGPASDPAWRRNDPMVNINQ
LVANNTRVWIYCGTGTPSELDAGTSGGNLMAAQFLEGFTLRTNVTFRDNYIAAGGTNGVFNFPSNGTHAWGYWGQQLQQM
KPDIQRVLGAQGAI

Specific function: Proteins of the antigen 85 complex are responsible for the high affinity of mycobacteria to fibronectin. Possesses a mycolyltransferase activity required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintain

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial A85 antigen family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: NA

Molecular weight: Translated: 36662; Mature: 36662

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVGKFRDTARRTWRRMAVVAVAAITLPGLIGFAGGSATAGAFSRPGLPVEYLDVFSQS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHH
MNRNIRIQFQGGGPHAVYLLDGLRAQDDYNGWDINTPAFEWYHQSGLSVVMPVGGQSSFY
HCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCEE
TDWYQPSRGNGQDYTYKWETFLTQELPAWLEANRGVSPSGNAVVGISMAGSTALTYSIYY
ECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEEEEC
PQKFVYAASLSGFLNPSEGWWPMLIGLAMQDSGKYNAESMWGPASDPAWRRNDPMVNINQ
CCCEEEEEHHHCCCCCCCCCCEEEEEEEECCCCCCCCHHCCCCCCCCCCCCCCCEEEHHH
LVANNTRVWIYCGTGTPSELDAGTSGGNLMAAQFLEGFTLRTNVTFRDNYIAAGGTNGVF
HHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCEEEEEEEEECCCEEEECCCCCEE
NFPSNGTHAWGYWGQQLQQMKPDIQRVLGAQGAI
ECCCCCCEECCHHHHHHHHHCHHHHHHHCCCCCC
>Mature Secondary Structure
MKFVGKFRDTARRTWRRMAVVAVAAITLPGLIGFAGGSATAGAFSRPGLPVEYLDVFSQS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHH
MNRNIRIQFQGGGPHAVYLLDGLRAQDDYNGWDINTPAFEWYHQSGLSVVMPVGGQSSFY
HCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCEE
TDWYQPSRGNGQDYTYKWETFLTQELPAWLEANRGVSPSGNAVVGISMAGSTALTYSIYY
ECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEEEEC
PQKFVYAASLSGFLNPSEGWWPMLIGLAMQDSGKYNAESMWGPASDPAWRRNDPMVNINQ
CCCEEEEEHHHCCCCCCCCCCEEEEEEEECCCCCCCCHHCCCCCCCCCCCCCCCEEEHHH
LVANNTRVWIYCGTGTPSELDAGTSGGNLMAAQFLEGFTLRTNVTFRDNYIAAGGTNGVF
HHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCEEEEEEEEECCCEEEECCCCCEE
NFPSNGTHAWGYWGQQLQQMKPDIQRVLGAQGAI
ECCCCCCEECCHHHHHHHHHCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]