Click here to switch to the map view.

The map label for this gene is fadB1 [H]

Identifier: 119868742

GI number: 119868742

Start: 2832023

End: 2832796

Strand: Direct

Name: fadB1 [H]

Synonym: Mkms_2709

Alternate gene names: 119868742

Gene position: 2832023-2832796 (Clockwise)

Preceding gene: 119868741

Following gene: 119868744

Centisome position: 49.36

GC content: 68.35

Gene sequence:

>774_bases
ATGACTCTCGTCACCTATGAGTTGGCCGACCACGTCGCCACCATCACCCTGAACCGGCCCGAGGCCCGCAACGCCATCAA
CGGAGCGCTGCGCGAGGACCTCAACGCCGCCTGGAACCGGTTCCGTGAGGACGAGGACGCCTGGGTCGGCATTCTCACCG
CGACCGGAGATGTCTTCTGCGCGGGAGGCGACCTCAAAGACGGCGCGGGCTCGGTCGGCACCTTCGCCGGGACGTTCTGG
GAGAAGCCCACCATCAACTCGTTCGAAAGCGGTATGGAGCTGTTCAAGCCGACCATCGCGGCAGTGCACGGGCCGTGCGT
CGGCTACGGCTTGACCGGAGTGTTGTTCTGCGACTTCGTGATCGCCAGCACCGCGGCCACCTTCTCGTTTCCCGAGGTGT
CGCTCGGAGTGCCCACCATCGTCGGCGCGATCCGGCTGCCCGAGCGGGTGCGCTGGGCCGACGCGATGGAGCTCCTCCTC
ACCGGCAAGCCCATGACGGCCCAACGGGCCAAGGAGGTGGGCCTGGTCTGGCGGCTGGTCGAGCCCGAGAACCTGCAGGC
CGAGGCGCAGGCGTGGGCCCGCACCCTGACCGAGGCCGCGCCGCTGGCTCAGCGGGCGACCAAGGAGGTGGCGTGGCGCA
CCGCGAACATGGGCTGGATCGAATCCGTCCGGTTCGGCGAGACCATGCGCAAGGTCGCCGCCGCCACCGACGATGTCGTC
GAAGGGATACAGGCGTGGCGCGACAAGCGCAAACCGCAGTGGAAAGGCCGCTGA

Upstream 100 bases:

>100_bases
CCGACGAAACGAGACCGCCGACGGCTCGACAGATGGCTCGCGGGGCAATGACTCCGAGCGTGTGAGGGAGCCGGTGACCC
GGCGAAACTAGGGTGCAGGC

Downstream 100 bases:

>100_bases
CGCGACGGCTCAGAACGCGTAGCGGATACGGCAGTCCGGCAGTCTGTCGGCGACCAGGTCGGTGAGCTGCTGCACCCACT
TTCCCTTCCAGGGGCTCTTG

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MTLVTYELADHVATITLNRPEARNAINGALREDLNAAWNRFREDEDAWVGILTATGDVFCAGGDLKDGAGSVGTFAGTFW
EKPTINSFESGMELFKPTIAAVHGPCVGYGLTGVLFCDFVIASTAATFSFPEVSLGVPTIVGAIRLPERVRWADAMELLL
TGKPMTAQRAKEVGLVWRLVEPENLQAEAQAWARTLTEAAPLAQRATKEVAWRTANMGWIESVRFGETMRKVAAATDDVV
EGIQAWRDKRKPQWKGR

Sequences:

>Translated_257_residues
MTLVTYELADHVATITLNRPEARNAINGALREDLNAAWNRFREDEDAWVGILTATGDVFCAGGDLKDGAGSVGTFAGTFW
EKPTINSFESGMELFKPTIAAVHGPCVGYGLTGVLFCDFVIASTAATFSFPEVSLGVPTIVGAIRLPERVRWADAMELLL
TGKPMTAQRAKEVGLVWRLVEPENLQAEAQAWARTLTEAAPLAQRATKEVAWRTANMGWIESVRFGETMRKVAAATDDVV
EGIQAWRDKRKPQWKGR
>Mature_256_residues
TLVTYELADHVATITLNRPEARNAINGALREDLNAAWNRFREDEDAWVGILTATGDVFCAGGDLKDGAGSVGTFAGTFWE
KPTINSFESGMELFKPTIAAVHGPCVGYGLTGVLFCDFVIASTAATFSFPEVSLGVPTIVGAIRLPERVRWADAMELLLT
GKPMTAQRAKEVGLVWRLVEPENLQAEAQAWARTLTEAAPLAQRATKEVAWRTANMGWIESVRFGETMRKVAAATDDVVE
GIQAWRDKRKPQWKGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=247, Percent_Identity=32.3886639676113, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI70995211, Length=254, Percent_Identity=28.3464566929134, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI260274832, Length=224, Percent_Identity=31.25, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI45643119, Length=224, Percent_Identity=31.25, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI260275230, Length=224, Percent_Identity=31.25, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI31542718, Length=258, Percent_Identity=28.2945736434109, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4502327, Length=254, Percent_Identity=27.9527559055118, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI20127408, Length=186, Percent_Identity=29.5698924731183, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI221307494, Length=241, Percent_Identity=26.1410788381743, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI221136756, Length=246, Percent_Identity=26.0162601626016, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI221136753, Length=246, Percent_Identity=26.0162601626016, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787659, Length=255, Percent_Identity=34.1176470588235, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI221142681, Length=260, Percent_Identity=34.2307692307692, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI87082183, Length=253, Percent_Identity=30.0395256916996, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787660, Length=266, Percent_Identity=30.8270676691729, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788597, Length=256, Percent_Identity=27.734375, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1788682, Length=192, Percent_Identity=30.2083333333333, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790281, Length=197, Percent_Identity=27.4111675126904, Blast_Score=64, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=259, Percent_Identity=34.7490347490347, Blast_Score=123, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17554946, Length=251, Percent_Identity=31.8725099601594, Blast_Score=118, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17535521, Length=209, Percent_Identity=31.1004784688995, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560910, Length=247, Percent_Identity=28.7449392712551, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17536985, Length=263, Percent_Identity=23.9543726235741, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=262, Percent_Identity=26.3358778625954, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17540306, Length=260, Percent_Identity=26.5384615384615, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=182, Percent_Identity=29.1208791208791, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17549921, Length=222, Percent_Identity=28.3783783783784, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17540714, Length=199, Percent_Identity=27.6381909547739, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI25144276, Length=214, Percent_Identity=29.9065420560748, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508951, Length=214, Percent_Identity=29.9065420560748, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508953, Length=214, Percent_Identity=29.9065420560748, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=201, Percent_Identity=27.8606965174129, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI20129971, Length=247, Percent_Identity=30.7692307692308, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24653477, Length=247, Percent_Identity=30.7692307692308, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21357171, Length=179, Percent_Identity=30.1675977653631, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24650670, Length=249, Percent_Identity=26.9076305220884, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24653139, Length=253, Percent_Identity=29.6442687747036, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI19922422, Length=256, Percent_Identity=24.609375, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19920382, Length=212, Percent_Identity=31.1320754716981, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24654903, Length=176, Percent_Identity=27.8409090909091, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28127; Mature: 27996

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVTYELADHVATITLNRPEARNAINGALREDLNAAWNRFREDEDAWVGILTATGDVFC
CEEEEEEHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEE
AGGDLKDGAGSVGTFAGTFWEKPTINSFESGMELFKPTIAAVHGPCVGYGLTGVLFCDFV
ECCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IASTAATFSFPEVSLGVPTIVGAIRLPERVRWADAMELLLTGKPMTAQRAKEVGLVWRLV
HHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEE
EPENLQAEAQAWARTLTEAAPLAQRATKEVAWRTANMGWIESVRFGETMRKVAAATDDVV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
EGIQAWRDKRKPQWKGR
HHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TLVTYELADHVATITLNRPEARNAINGALREDLNAAWNRFREDEDAWVGILTATGDVFC
EEEEEEHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEE
AGGDLKDGAGSVGTFAGTFWEKPTINSFESGMELFKPTIAAVHGPCVGYGLTGVLFCDFV
ECCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IASTAATFSFPEVSLGVPTIVGAIRLPERVRWADAMELLLTGKPMTAQRAKEVGLVWRLV
HHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEE
EPENLQAEAQAWARTLTEAAPLAQRATKEVAWRTANMGWIESVRFGETMRKVAAATDDVV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
EGIQAWRDKRKPQWKGR
HHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]