BacMap

Definition	Mycobacterium sp. KMS chromosome, complete genome.
Accession	NC_008705
Length	5,737,227

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The map label for this gene is yghA [C]

Identifier: 119868702

GI number: 119868702

Start: 2801891

End: 2802637

Strand: Direct

Name: yghA [C]

Synonym: Mkms_2669

Alternate gene names: 119868702

Gene position: 2801891-2802637 (Clockwise)

Preceding gene: 119868698

Following gene: 119868705

Centisome position: 48.84

GC content: 66.93

Gene sequence:

>747_bases
ATGGCCCGAATTGCGCTCGTGACCGGCGCCAACCGCGGACTCGGACGAGCCACCGCGCTCGCGTTGGCCAGGAACAAGAT
CCGAGTCGTCGCAGCCTCGCGAAATGGTGCGAGTGGGGTCGTGGACGACATCGTCGAAGCGGGAGGTGAAGCCATCGCGG
TCCAGTTGGATGTCGCAGACCTCTCATCCGTCGAGGCGGCGCGCGTCGCTGCGCTCGCCGGCATCGGGCAGGAGTGGAAC
GCCAGCACCATCGACGTGCTGGTCAACAACGCCGGGGTGGGCCTGTTCGCGCCGCTCGGCGCCATCACGGTCGAAGACTT
CGACGCCACCTTCGCCGTCAACGTTCGTGGCCCGCTTTTCGTCACCCAAGCTTTCTTGCCCCACCTGTCGGAAGGAGCAA
GCATCGTGAACGTGTCGAGTTCGCTCAGCCGACACGTCAGCCCGGCGGCCTCCGTCTACGCGGCATCGAAGAAGGCACTC
GAAGCACTTACCCGCAGCCTCGCCCTCGAACTCGGCCCGCGGGGCATTCGGGTCAACTCGATCGCGCCCGGCCCGACCGC
GACCGACTTCAACGGCGGAGCCATGCGCGACAGCGAAGCCATGCGAGCGGAACTCTCCGGACAAACCGCCCTCGGGCGAG
TGGGCGACCCGGATGACATCGCCGAGGCGATCTGCGCCCTCGTGTCCCGTGAGTTCCGCTGGGCAACCGGTGAACGCCTC
GAGGTATCCGGTGGCGTGTTGCTGTGA

Upstream 100 bases:

>100_bases
CGCGGGCCATTACCCTCTCCCCTGCTTTGAATTGACGGCATCACCGGCACGGGCTAGCTTACAAGTAAGTATCCATTTAC
TTATCTGATGTGGGGACGAC

Downstream 100 bases:

>100_bases
CCGGACGCGGCGTCACCCGAGCCGCCGAGTGCGCCACCGCGACAGATCCGCATCGAGCACCGCCGAATCGCGTTCGGGAA
ACACCTCGCCGGTGATCTCC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: ORFC [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MARIALVTGANRGLGRATALALARNKIRVVAASRNGASGVVDDIVEAGGEAIAVQLDVADLSSVEAARVAALAGIGQEWN
ASTIDVLVNNAGVGLFAPLGAITVEDFDATFAVNVRGPLFVTQAFLPHLSEGASIVNVSSSLSRHVSPAASVYAASKKAL
EALTRSLALELGPRGIRVNSIAPGPTATDFNGGAMRDSEAMRAELSGQTALGRVGDPDDIAEAICALVSREFRWATGERL
EVSGGVLL

Sequences:

>Translated_248_residues
MARIALVTGANRGLGRATALALARNKIRVVAASRNGASGVVDDIVEAGGEAIAVQLDVADLSSVEAARVAALAGIGQEWN
ASTIDVLVNNAGVGLFAPLGAITVEDFDATFAVNVRGPLFVTQAFLPHLSEGASIVNVSSSLSRHVSPAASVYAASKKAL
EALTRSLALELGPRGIRVNSIAPGPTATDFNGGAMRDSEAMRAELSGQTALGRVGDPDDIAEAICALVSREFRWATGERL
EVSGGVLL
>Mature_247_residues
ARIALVTGANRGLGRATALALARNKIRVVAASRNGASGVVDDIVEAGGEAIAVQLDVADLSSVEAARVAALAGIGQEWNA
STIDVLVNNAGVGLFAPLGAITVEDFDATFAVNVRGPLFVTQAFLPHLSEGASIVNVSSSLSRHVSPAASVYAASKKALE
ALTRSLALELGPRGIRVNSIAPGPTATDFNGGAMRDSEAMRAELSGQTALGRVGDPDDIAEAICALVSREFRWATGERLE
VSGGVLL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=36.5853658536585, Blast_Score=117, Evalue=7e-27,
Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=34.6613545816733, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=32.3886639676113, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=31.3492063492063, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=33.4630350194552, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=37.5, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI10190704, Length=260, Percent_Identity=29.6153846153846, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI33667109, Length=267, Percent_Identity=32.5842696629214, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI7657478, Length=211, Percent_Identity=33.6492890995261, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=28.740157480315, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI223718074, Length=201, Percent_Identity=36.318407960199, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI4504505, Length=262, Percent_Identity=31.2977099236641, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI302344755, Length=101, Percent_Identity=43.5643564356436, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI20149619, Length=236, Percent_Identity=29.2372881355932, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI19923817, Length=263, Percent_Identity=26.9961977186312, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=30.2564102564103, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=30.6034482758621, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI44680136, Length=191, Percent_Identity=28.7958115183246, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI44680133, Length=191, Percent_Identity=28.7958115183246, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI17738292, Length=191, Percent_Identity=28.7958115183246, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI142976729, Length=199, Percent_Identity=31.6582914572864, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI31542939, Length=198, Percent_Identity=31.3131313131313, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI210032110, Length=192, Percent_Identity=30.2083333333333, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=33.9920948616601, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI2367175, Length=255, Percent_Identity=36.078431372549, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=32.6771653543307, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=33.2, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=32.1285140562249, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=31.3253012048193, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=32.156862745098, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=29.8387096774194, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=30.241935483871, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=29.8804780876494, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=32.6771653543307, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786701, Length=195, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1787820, Length=226, Percent_Identity=28.3185840707965, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787526, Length=249, Percent_Identity=31.3253012048193, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787545, Length=251, Percent_Identity=26.6932270916335, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=38.3064516129032, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=33.4645669291339, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=34.4262295081967, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=34.3629343629344, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=32.4528301886792, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=33.203125, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI193204405, Length=258, Percent_Identity=31.7829457364341, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17531453, Length=258, Percent_Identity=31.3953488372093, Blast_Score=97, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17561402, Length=266, Percent_Identity=31.9548872180451, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=32.089552238806, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=32.0754716981132, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=275, Percent_Identity=30.5454545454545, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=30.3149606299213, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560220, Length=259, Percent_Identity=30.8880308880309, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=29.3893129770992, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=29.0566037735849, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=273, Percent_Identity=30.4029304029304, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=270, Percent_Identity=32.962962962963, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=29.4339622641509, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=31.5985130111524, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=29.7709923664122, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=269, Percent_Identity=31.5985130111524, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17508651, Length=258, Percent_Identity=29.8449612403101, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=32.0610687022901, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=194, Percent_Identity=34.5360824742268, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71982365, Length=199, Percent_Identity=28.643216080402, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=28.0898876404494, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=208, Percent_Identity=29.3269230769231, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=26.7716535433071, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17557780, Length=209, Percent_Identity=28.2296650717703, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17558006, Length=206, Percent_Identity=30.5825242718447, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=257, Percent_Identity=28.7937743190661, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=254, Percent_Identity=25.1968503937008, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17558628, Length=195, Percent_Identity=28.2051282051282, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=240, Percent_Identity=32.5, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322861, Length=194, Percent_Identity=30.4123711340206, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=26.984126984127, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=36.2139917695473, Blast_Score=124, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=34.9397590361446, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=34.9206349206349, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=36.4, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=35.6, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=32.9317269076305, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24644337, Length=221, Percent_Identity=35.2941176470588, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21358495, Length=237, Percent_Identity=28.6919831223629, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357673, Length=250, Percent_Identity=28.4, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=29.9212598425197, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24656154, Length=213, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI19922628, Length=213, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24647946, Length=199, Percent_Identity=34.1708542713568, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45553409, Length=199, Percent_Identity=34.1708542713568, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647948, Length=199, Percent_Identity=34.1708542713568, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24580925, Length=234, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI18859837, Length=197, Percent_Identity=32.48730964467, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640442, Length=196, Percent_Identity=27.5510204081633, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25342; Mature: 25211

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIALVTGANRGLGRATALALARNKIRVVAASRNGASGVVDDIVEAGGEAIAVQLDVAD
CCEEEEEECCCCCCCHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHCCCCEEEEEEEHHC
LSSVEAARVAALAGIGQEWNASTIDVLVNNAGVGLFAPLGAITVEDFDATFAVNVRGPLF
CCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEECCCEEEEECCCCEEEEECCCCCH
VTQAFLPHLSEGASIVNVSSSLSRHVSPAASVYAASKKALEALTRSLALELGPRGIRVNS
HHHHHHHHHCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
IAPGPTATDFNGGAMRDSEAMRAELSGQTALGRVGDPDDIAEAICALVSREFRWATGERL
CCCCCCCCCCCCCCCCCHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEE
EVSGGVLL
EECCCCCC
>Mature Secondary Structure 
ARIALVTGANRGLGRATALALARNKIRVVAASRNGASGVVDDIVEAGGEAIAVQLDVAD
CEEEEEECCCCCCCHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHCCCCEEEEEEEHHC
LSSVEAARVAALAGIGQEWNASTIDVLVNNAGVGLFAPLGAITVEDFDATFAVNVRGPLF
CCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEECCCEEEEECCCCEEEEECCCCCH
VTQAFLPHLSEGASIVNVSSSLSRHVSPAASVYAASKKALEALTRSLALELGPRGIRVNS
HHHHHHHHHCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
IAPGPTATDFNGGAMRDSEAMRAELSGQTALGRVGDPDDIAEAICALVSREFRWATGERL
CCCCCCCCCCCCCCCCCHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEE
EVSGGVLL
EECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8868443 [H]