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The map label for this gene is adhR [H]

Identifier: 119868697

GI number: 119868697

Start: 2798013

End: 2798492

Strand: Direct

Name: adhR [H]

Synonym: Mkms_2664

Alternate gene names: 119868697

Gene position: 2798013-2798492 (Clockwise)

Preceding gene: 119868696

Following gene: 119868698

Centisome position: 48.77

GC content: 64.38

Gene sequence:

>480_bases
ATGTCCACCGACGACCTGATGACCAAGGCCCTCGCCTCACTCGGCGAGATCGACGGTCCGATGTCGATCGAGGTGATCCA
TCGCCTCGCCGCCACCACTGAGGTCCGCGCTTCGATGAGTATCGCCGAGGTCGCCGAGTTGCTCGACGTCTCCGCGCATA
CCCTGCGCTACTACGAACGCGTCGGCCTGGTCGAGGTGGACCGCGACAGCAGCGGCCACCGCAGCTACCGTCCCGCGGCG
GTGCGTCGGCTTGTCTTCCTCACTCGGATGCGGTTGTCCGGCATGGCTATCCGCGATCTACAGCACTATATCGCGCTCGT
CGACAGCGGTGATCAGACCGTACCCGAACGACTCGACATGCTGCTCGAACACCGCGACACCATCCGCCGCCAGATCCGTG
AACTCACCCTTTCCCTGGCTGCCACCGAATACAAGATCACCACCTACGGCGGTACCACCGGCGACACCGGTGCGCGGTAG

Upstream 100 bases:

>100_bases
ATCGACGCAGTCTGGAGGAGGTCAGCCAGTGGGCTGAGCTTGCGCGCAGCGCCGACTTCGCCGACGTCCCCGCCTCAATG
CGTCCGATCTAGGATCGGGT

Downstream 100 bases:

>100_bases
CAACTGCCAGTTGGGCTACCCCACGATCGTCGGCCCCTGGCGGTCGGTCAGCCCAGGGCGAACGCGATACCGAGGTGCCA
GATCCCTGGTTAACGTGATC

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MSTDDLMTKALASLGEIDGPMSIEVIHRLAATTEVRASMSIAEVAELLDVSAHTLRYYERVGLVEVDRDSSGHRSYRPAA
VRRLVFLTRMRLSGMAIRDLQHYIALVDSGDQTVPERLDMLLEHRDTIRRQIRELTLSLAATEYKITTYGGTTGDTGAR

Sequences:

>Translated_159_residues
MSTDDLMTKALASLGEIDGPMSIEVIHRLAATTEVRASMSIAEVAELLDVSAHTLRYYERVGLVEVDRDSSGHRSYRPAA
VRRLVFLTRMRLSGMAIRDLQHYIALVDSGDQTVPERLDMLLEHRDTIRRQIRELTLSLAATEYKITTYGGTTGDTGAR
>Mature_158_residues
STDDLMTKALASLGEIDGPMSIEVIHRLAATTEVRASMSIAEVAELLDVSAHTLRYYERVGLVEVDRDSSGHRSYRPAAV
RRLVFLTRMRLSGMAIRDLQHYIALVDSGDQTVPERLDMLLEHRDTIRRQIRELTLSLAATEYKITTYGGTTGDTGAR

Specific function: Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon, the yraC and its own promoter region; binding is unchanged in the presence of aldehydes [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 17751; Mature: 17619

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDDLMTKALASLGEIDGPMSIEVIHRLAATTEVRASMSIAEVAELLDVSAHTLRYYER
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGLVEVDRDSSGHRSYRPAAVRRLVFLTRMRLSGMAIRDLQHYIALVDSGDQTVPERLDM
CCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHH
LLEHRDTIRRQIRELTLSLAATEYKITTYGGTTGDTGAR
HHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
STDDLMTKALASLGEIDGPMSIEVIHRLAATTEVRASMSIAEVAELLDVSAHTLRYYER
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGLVEVDRDSSGHRSYRPAAVRRLVFLTRMRLSGMAIRDLQHYIALVDSGDQTVPERLDM
CCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHH
LLEHRDTIRRQIRELTLSLAATEYKITTYGGTTGDTGAR
HHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377 [H]