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The map label for this gene is sdcS [H]

Identifier: 119868654

GI number: 119868654

Start: 2753300

End: 2754904

Strand: Reverse

Name: sdcS [H]

Synonym: Mkms_2619

Alternate gene names: 119868654

Gene position: 2754904-2753300 (Counterclockwise)

Preceding gene: 119868655

Following gene: 119868653

Centisome position: 48.02

GC content: 67.04

Gene sequence:

>1605_bases
ATGACCGCCGACAATCCGGTCAAACGCACTGACGTGGACAAGGCGTTGCTCGGCAGCGCCACCTATCGCAGTCTCGGTGA
ACAGCGCCTGACGCCGGCCGAGGAGCGCTTCGAGAAGGGGCGCCGCACCGTCGGCCTGTTCCTCGCGCCCGCCCTCACGG
TCGTCTTCCTGCTGTTGCCGCTGGACCTCCCGCCGCAGCAACAGACGCTGGCCGCCGTGCTGCTCGGGGTGATCGTGCTG
TGGGTGACCGAGGCGGTGCCGATTCCGATCGGTGGTCTGCTCGGCGTCGCGGTCGTGGTCTTCCTCGGCGTGGCACCCGC
CGACGACGTACTGGCACCGTTCGGATCGTCGACGATCTTCACGTTCATCGGCGCCTTCATCCTCGCCCAGGCCATGCTCA
AGCACGGTCTGGCACGGCGATTCGCGTTCCGCATCCTCGCGCTGCCGCGGGCGGGTCAGTCGACCACCGGTGTCATCCTG
GCCTTCGGGGCGATCACCTGTCTGCTGTCGGCGTTCGTCTCCAACACCGCGACCGTCGCGATGTTGTTGCCCACCGCGAT
CGGCATCCTCGGCGTGATCGCCAAACTGCTGCAGAAGCAGGGCAAGGTGGCCGACGATTTCGACCCGCTGCGGCTGAGGG
TCGGTGCGGCACTCATGCTGATGCTCGCCTACTCCGCCAGCGTCGGCGGTCTGCTGACACCGGTGGGCAGCCCTCCGAAC
CTCATCGGCCGCGGCCTCATCGAAGAGGCCACCGGCGAGCGCATCAGCTTCGGCCAGTGGATGGTCATGGCCGCACCGAT
CTGCCTGCTGATGTTCGCGATCCTGGCGGTCGTCCTGCTCCTCCTGAACAAGCCGGAACTCAAGCACATCGACGGAGTCG
CCGACTACGTGGCCCGCGAGCGCGAGGAGATGGGCAGGCTCTCGAGGGCCGAGAAGAACACGCTGATCGCCTTCGGGGTG
ACGGTCTTCCTGTGGATACTGCCGGGCATCATCGCGCTGGCCTTCGGCAACGACTCCGACATCTACTCCTCGGTCAGTGA
CCGGTTGGACGAGGGCACCGTCGCGGTCTTCGGCGCGGCGCTGCTGTTCCTGCTGCCCACCGAGTGGGAACAGCGCGAGT
TCACGTTGCGCTGGAGGGATGCGGCCGCGATCGACTGGGGCACGATCGTCCTGTTCGGGACGGGCATCATCTTCGGATCG
CTGCTCGCCGACTCCGGACTGGCCGAGACGATCGGCAACTCGGTCGCCGACGCGCTCGGCCTGTCGAGCGTCGTGGCGAT
CACCATCTTCGCCGTCCTGCTCGCCATCGTCGTCTCGGAGACCACGAGCAATACCGCGTCGGCGGCGGTCGTCGTCCCCA
TCGTCATCCCGGTCGCCATCGCCGCCGGCGTCAACCCGTTCGTACCCGCACTGGCGGCCACGTTCGCCGCATCCTTCGGC
TTCATGCTGCCGGTCTCGACACCGCAGAACGCGATCGTCTACGGCTCCGGCGCCGTCCCGATCACGACGATGATCCGCTC
CGGTGTCACGTTCGACGTCGCCGGCGCCATCTTGATCATCCTCTTCCTGCCGCTGATGATCGCCCTGCTCGGGCTCGGAG
CATGA

Upstream 100 bases:

>100_bases
GACTTCCGGTCGACGGTTACTTCCGGCCAGGATCGGGCATCCTCCGCGCGTGTGAGCCACCTCACACCATGGGGAGCCGA
TCGGCCTCGAAGGGGGCAGC

Downstream 100 bases:

>100_bases
GCGCACACCGTATCGCCGTCATCCCCGGCGACGGGATCGGCACGGAGGCGACGGCCTCGGCGCGCACGGTGCTCGACGCG
GTCGCCGAGCGCCACGGGAT

Product: anion transporter

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MTADNPVKRTDVDKALLGSATYRSLGEQRLTPAEERFEKGRRTVGLFLAPALTVVFLLLPLDLPPQQQTLAAVLLGVIVL
WVTEAVPIPIGGLLGVAVVVFLGVAPADDVLAPFGSSTIFTFIGAFILAQAMLKHGLARRFAFRILALPRAGQSTTGVIL
AFGAITCLLSAFVSNTATVAMLLPTAIGILGVIAKLLQKQGKVADDFDPLRLRVGAALMLMLAYSASVGGLLTPVGSPPN
LIGRGLIEEATGERISFGQWMVMAAPICLLMFAILAVVLLLLNKPELKHIDGVADYVAREREEMGRLSRAEKNTLIAFGV
TVFLWILPGIIALAFGNDSDIYSSVSDRLDEGTVAVFGAALLFLLPTEWEQREFTLRWRDAAAIDWGTIVLFGTGIIFGS
LLADSGLAETIGNSVADALGLSSVVAITIFAVLLAIVVSETTSNTASAAVVVPIVIPVAIAAGVNPFVPALAATFAASFG
FMLPVSTPQNAIVYGSGAVPITTMIRSGVTFDVAGAILIILFLPLMIALLGLGA

Sequences:

>Translated_534_residues
MTADNPVKRTDVDKALLGSATYRSLGEQRLTPAEERFEKGRRTVGLFLAPALTVVFLLLPLDLPPQQQTLAAVLLGVIVL
WVTEAVPIPIGGLLGVAVVVFLGVAPADDVLAPFGSSTIFTFIGAFILAQAMLKHGLARRFAFRILALPRAGQSTTGVIL
AFGAITCLLSAFVSNTATVAMLLPTAIGILGVIAKLLQKQGKVADDFDPLRLRVGAALMLMLAYSASVGGLLTPVGSPPN
LIGRGLIEEATGERISFGQWMVMAAPICLLMFAILAVVLLLLNKPELKHIDGVADYVAREREEMGRLSRAEKNTLIAFGV
TVFLWILPGIIALAFGNDSDIYSSVSDRLDEGTVAVFGAALLFLLPTEWEQREFTLRWRDAAAIDWGTIVLFGTGIIFGS
LLADSGLAETIGNSVADALGLSSVVAITIFAVLLAIVVSETTSNTASAAVVVPIVIPVAIAAGVNPFVPALAATFAASFG
FMLPVSTPQNAIVYGSGAVPITTMIRSGVTFDVAGAILIILFLPLMIALLGLGA
>Mature_533_residues
TADNPVKRTDVDKALLGSATYRSLGEQRLTPAEERFEKGRRTVGLFLAPALTVVFLLLPLDLPPQQQTLAAVLLGVIVLW
VTEAVPIPIGGLLGVAVVVFLGVAPADDVLAPFGSSTIFTFIGAFILAQAMLKHGLARRFAFRILALPRAGQSTTGVILA
FGAITCLLSAFVSNTATVAMLLPTAIGILGVIAKLLQKQGKVADDFDPLRLRVGAALMLMLAYSASVGGLLTPVGSPPNL
IGRGLIEEATGERISFGQWMVMAAPICLLMFAILAVVLLLLNKPELKHIDGVADYVAREREEMGRLSRAEKNTLIAFGVT
VFLWILPGIIALAFGNDSDIYSSVSDRLDEGTVAVFGAALLFLLPTEWEQREFTLRWRDAAAIDWGTIVLFGTGIIFGSL
LADSGLAETIGNSVADALGLSSVVAITIFAVLLAIVVSETTSNTASAAVVVPIVIPVAIAAGVNPFVPALAATFAASFGF
MLPVSTPQNAIVYGSGAVPITTMIRSGVTFDVAGAILIILFLPLMIALLGLGA

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=521, Percent_Identity=28.4069097888676, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI31377715, Length=570, Percent_Identity=27.0175438596491, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI58761541, Length=524, Percent_Identity=26.9083969465649, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI301069349, Length=506, Percent_Identity=25.6916996047431, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI301069346, Length=528, Percent_Identity=27.0833333333333, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI4506979, Length=513, Percent_Identity=26.3157894736842, Blast_Score=137, Evalue=4e-32,
Organism=Homo sapiens, GI225637552, Length=470, Percent_Identity=26.8085106382979, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI225637549, Length=470, Percent_Identity=26.8085106382979, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI301069353, Length=475, Percent_Identity=26.3157894736842, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI219802232, Length=454, Percent_Identity=27.0925110132159, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI31795546, Length=343, Percent_Identity=28.8629737609329, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI19923838, Length=364, Percent_Identity=24.7252747252747, Blast_Score=100, Evalue=6e-21,
Organism=Escherichia coli, GI1786829, Length=505, Percent_Identity=25.1485148514851, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1789444, Length=505, Percent_Identity=23.7623762376238, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71988385, Length=481, Percent_Identity=28.6902286902287, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI32565804, Length=464, Percent_Identity=28.8793103448276, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI32564681, Length=503, Percent_Identity=27.037773359841, Blast_Score=151, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17551790, Length=509, Percent_Identity=26.1296660117878, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71989118, Length=494, Percent_Identity=25.7085020242915, Blast_Score=134, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6319885, Length=413, Percent_Identity=25.6658595641646, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322263, Length=423, Percent_Identity=26.0047281323877, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324340, Length=419, Percent_Identity=22.673031026253, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281362116, Length=489, Percent_Identity=25.3578732106339, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281362114, Length=489, Percent_Identity=25.7668711656442, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281362112, Length=489, Percent_Identity=25.7668711656442, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI45551633, Length=542, Percent_Identity=25.0922509225092, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281366409, Length=542, Percent_Identity=25.0922509225092, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI17737623, Length=542, Percent_Identity=25.0922509225092, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24666468, Length=542, Percent_Identity=25.0922509225092, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI78706796, Length=459, Percent_Identity=25.2723311546841, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI78706798, Length=459, Percent_Identity=25.2723311546841, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 55945; Mature: 55814

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS01271 NA_SULFATE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADNPVKRTDVDKALLGSATYRSLGEQRLTPAEERFEKGRRTVGLFLAPALTVVFLLLP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHC
LDLPPQQQTLAAVLLGVIVLWVTEAVPIPIGGLLGVAVVVFLGVAPADDVLAPFGSSTIF
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCHHHH
TFIGAFILAQAMLKHGLARRFAFRILALPRAGQSTTGVILAFGAITCLLSAFVSNTATVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHH
MLLPTAIGILGVIAKLLQKQGKVADDFDPLRLRVGAALMLMLAYSASVGGLLTPVGSPPN
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
LIGRGLIEEATGERISFGQWMVMAAPICLLMFAILAVVLLLLNKPELKHIDGVADYVARE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
REEMGRLSRAEKNTLIAFGVTVFLWILPGIIALAFGNDSDIYSSVSDRLDEGTVAVFGAA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCHHHHHHHH
LLFLLPTEWEQREFTLRWRDAAAIDWGTIVLFGTGIIFGSLLADSGLAETIGNSVADALG
HHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LSSVVAITIFAVLLAIVVSETTSNTASAAVVVPIVIPVAIAAGVNPFVPALAATFAASFG
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
FMLPVSTPQNAIVYGSGAVPITTMIRSGVTFDVAGAILIILFLPLMIALLGLGA
CEEECCCCCCEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TADNPVKRTDVDKALLGSATYRSLGEQRLTPAEERFEKGRRTVGLFLAPALTVVFLLLP
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHC
LDLPPQQQTLAAVLLGVIVLWVTEAVPIPIGGLLGVAVVVFLGVAPADDVLAPFGSSTIF
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCHHHH
TFIGAFILAQAMLKHGLARRFAFRILALPRAGQSTTGVILAFGAITCLLSAFVSNTATVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHH
MLLPTAIGILGVIAKLLQKQGKVADDFDPLRLRVGAALMLMLAYSASVGGLLTPVGSPPN
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
LIGRGLIEEATGERISFGQWMVMAAPICLLMFAILAVVLLLLNKPELKHIDGVADYVARE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
REEMGRLSRAEKNTLIAFGVTVFLWILPGIIALAFGNDSDIYSSVSDRLDEGTVAVFGAA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCHHHHHHHH
LLFLLPTEWEQREFTLRWRDAAAIDWGTIVLFGTGIIFGSLLADSGLAETIGNSVADALG
HHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LSSVVAITIFAVLLAIVVSETTSNTASAAVVVPIVIPVAIAAGVNPFVPALAATFAASFG
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
FMLPVSTPQNAIVYGSGAVPITTMIRSGVTFDVAGAILIILFLPLMIALLGLGA
CEEECCCCCCEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA