Click here to switch to the map view.

The map label for this gene is dmsA [H]

Identifier: 119868248

GI number: 119868248

Start: 2326545

End: 2328833

Strand: Reverse

Name: dmsA [H]

Synonym: Mkms_2212

Alternate gene names: 119868248

Gene position: 2328833-2326545 (Counterclockwise)

Preceding gene: 119868250

Following gene: 119868241

Centisome position: 40.59

GC content: 69.07

Gene sequence:

>2289_bases
ATGCCCGCCCGCCCGACCAGCCTCACCCATTGGGGCGGTTTCTCCGCCGAGGTTTCGTCCGGTGACATCGCGGCCGTCAC
ACCTCTGCCCGGCGACGACGATCCCTCTCCCCTGCTGGGCAATCTGCCCGGTTCGGTGCGGCACCGTTCGCGCATCGCGG
GTCCGGCCATCCGGCGCGGCTGGCTCGACGACGGGCCGGGCCCCAGCCGGCGACGCGGCGCGGACGAATTCGTCGCCGTG
TCGTGGGATGAGCTCACCGACCTTCTCGCGGCCGAACTGCGCCGTGTGGTCGACACCCACGGCAACGAGGCCATCTACGG
CGGTTCGTACGGGTGGGCCAGCGCGGGCCGGTTCCACCACGCCCAGAGCCAGGTGCACCGCTTCCTGAAACTGCTTGGCG
GTTACACCTATTCGCGTCACTCCTACAGCCTCGGCGCGACGGGGGTGATCATGCCACGCGTCGTCGGCACCCACGACGAT
CTGTTCAAACGCTCCACCGACTGGGACGTCATCGCCGCGCGCACCGATCTGCTGGTGTGCTTCGGCGGGTTGGCGATGAA
GAACACCGGCACCAATCACGGTGGAACGACGGCACATCCGGCCCGCGCCGCACTGCGCCGGTTCCGCGGCCGCGGCGGCC
GGATCGTGTCGTTCTCACCGCTGCGCGACGACGTCGACGGTGAGTGTGATTGGTACGCACCGGTGCCGGGCACCGATGTC
GCGATCATGTTGGGCTTGGCCTATGTGCTGGCCACCGAACGACTGGCCGACCGCGGGTTCCTCGAGACTCACTGCGTCGG
CTACGACCGTTTCGAGCGGTACCTGCTCGGCGCCGACGACGGTGTCGCGAAGAGCCCGCAGTGGGCGGCGGCGATCTGCG
GTCTGCCCGCCGACGAGATCACCGCGCTGGCCCGGCGGATGGCGGCGCAGCGCACCATCGTCACCGTCAGTTGGTCGCTG
CAGCGGGTCCGGCACGGTGAGCAAGCCCCGTGGATGGGTTTGACGCTGGCCGCGATGCTGGGTCAGATCGGCCTTCCCGG
AGGGGGTTTCGGGCATGGCTACGGATCGATGAACGAACCGGGGTTGCCGCCGTTGCGTTGTGGTCTGCCGCGGCTGCCGC
AGGGCATCAACCCGGTGAGCACGTTCATCCCGGTCGCCGCGGTCAGCGATATGCTGCTGCACCCCGGTGAGACGTTCGAC
TACAACGGGATGCGGTTGACCTACCCCGACATCCGTTGCGTGTACTGGGCCGGCGGCAACCCGTTCCACCACCACCAGAA
CATCCCCCGGCTGCGGCGGGCGCTGGCCCGCGTGGACACCGTCGTCGTGCACGATCCGTACTGGACCGCGATGGCCAAAC
ACGCCGACATCGTGGTGCCCTCCACCACGGCGTTCGAACGCGAGGACTACTCGGGTTCGAAGAACGATCCCGTGCTGATG
GCGATGCCGAAACTGGTCGAACCGTATGCCGACAGCCGCGACGACTACACGACGTTCGCCGCGCTGGCCGACCGGCTCGG
ATTCGGCGAACAGTTCACCGAAGGGCGCACCGCCCGGCAGTGGCTCGCCCACCTCTACGAGAAGTGGTCGGCGGAGCTGG
ATTTCGCGGTGCCGACCTTCGAGCAGTTCTGGCGCGACGGCAGCCTCCGCCTGCCCACCGAACCGGGCCTGACGCTGCTG
GGCGACTTCCGCGCCGACCCCGTCGCGCACCGGCTCGGCACCCCGAGTGGCCGCATCGAGATCTTCTCCGAGGACATCGC
GGGTTTCGGCTATGCCGATTGCGCGGGACATCCCACCTGGTTCGAGCCCACCGAGTGGCTCGGCGGCGAACGTGCCGCGA
CGTATCCGCTACACCTCGTCGCCAACCAGCCGGCGACCCGGCTGCACGGCCAGCTCGACGGCGGTTCCACCAGTCAGTCC
GCGAAAGTCGTTGGCCGCGAAGCCATCAGGATGCATCCCGATGACGCCGCCGCCCGCGGTGTGGCCGACGGCGACGTGGT
GCGGGTGTTCAACGACCGCGGCGCCTGCCTCGCCGGTGCGGTGATCGATGACCGGCTGCGGCGCAGTGTCGTACAGCTGC
CGACGGGCGCCTGGTTCGATCCGGCCGACCCGGCCGACTACGACGCGATGTGCGTACACGGCAATCCCAACGTGCTGACC
GACGACGTCGGCACCTCGTCGCTGGCTCGTGGCAGCACCGGGGCCCATGTGCTGGTGCAGGTCGAGAAATTCTCCGGTCC
GATCCCGCCGGTGCGGGCGCACGAACCGCCGGTGATCCGGCAGCGCTGA

Upstream 100 bases:

>100_bases
TCCGACCATAGGGGCCCGAAACCGTGCGATCGGGTGCTGCCGACCGCGCGGCGGCCCGCTGCGCTGCGGTGTGAGATCGC
GCGGTCCTAGACTTCCCGCC

Downstream 100 bases:

>100_bases
CAGAGAAACACCGCCCCGGTGTGGGGCGGTGTTCCTGTGTCGGCTCTAGCGGGCGGCCTGTGGGCGTCGGCGCGGACCGC
GCGAACGCGTACCGGCGCCG

Product: molybdopterin guanine dinucleotide-containing S/N-oxide reductases

Products: Biotin [C]

Alternate protein names: DMSO reductase; DMSOR [H]

Number of amino acids: Translated: 762; Mature: 761

Protein sequence:

>762_residues
MPARPTSLTHWGGFSAEVSSGDIAAVTPLPGDDDPSPLLGNLPGSVRHRSRIAGPAIRRGWLDDGPGPSRRRGADEFVAV
SWDELTDLLAAELRRVVDTHGNEAIYGGSYGWASAGRFHHAQSQVHRFLKLLGGYTYSRHSYSLGATGVIMPRVVGTHDD
LFKRSTDWDVIAARTDLLVCFGGLAMKNTGTNHGGTTAHPARAALRRFRGRGGRIVSFSPLRDDVDGECDWYAPVPGTDV
AIMLGLAYVLATERLADRGFLETHCVGYDRFERYLLGADDGVAKSPQWAAAICGLPADEITALARRMAAQRTIVTVSWSL
QRVRHGEQAPWMGLTLAAMLGQIGLPGGGFGHGYGSMNEPGLPPLRCGLPRLPQGINPVSTFIPVAAVSDMLLHPGETFD
YNGMRLTYPDIRCVYWAGGNPFHHHQNIPRLRRALARVDTVVVHDPYWTAMAKHADIVVPSTTAFEREDYSGSKNDPVLM
AMPKLVEPYADSRDDYTTFAALADRLGFGEQFTEGRTARQWLAHLYEKWSAELDFAVPTFEQFWRDGSLRLPTEPGLTLL
GDFRADPVAHRLGTPSGRIEIFSEDIAGFGYADCAGHPTWFEPTEWLGGERAATYPLHLVANQPATRLHGQLDGGSTSQS
AKVVGREAIRMHPDDAAARGVADGDVVRVFNDRGACLAGAVIDDRLRRSVVQLPTGAWFDPADPADYDAMCVHGNPNVLT
DDVGTSSLARGSTGAHVLVQVEKFSGPIPPVRAHEPPVIRQR

Sequences:

>Translated_762_residues
MPARPTSLTHWGGFSAEVSSGDIAAVTPLPGDDDPSPLLGNLPGSVRHRSRIAGPAIRRGWLDDGPGPSRRRGADEFVAV
SWDELTDLLAAELRRVVDTHGNEAIYGGSYGWASAGRFHHAQSQVHRFLKLLGGYTYSRHSYSLGATGVIMPRVVGTHDD
LFKRSTDWDVIAARTDLLVCFGGLAMKNTGTNHGGTTAHPARAALRRFRGRGGRIVSFSPLRDDVDGECDWYAPVPGTDV
AIMLGLAYVLATERLADRGFLETHCVGYDRFERYLLGADDGVAKSPQWAAAICGLPADEITALARRMAAQRTIVTVSWSL
QRVRHGEQAPWMGLTLAAMLGQIGLPGGGFGHGYGSMNEPGLPPLRCGLPRLPQGINPVSTFIPVAAVSDMLLHPGETFD
YNGMRLTYPDIRCVYWAGGNPFHHHQNIPRLRRALARVDTVVVHDPYWTAMAKHADIVVPSTTAFEREDYSGSKNDPVLM
AMPKLVEPYADSRDDYTTFAALADRLGFGEQFTEGRTARQWLAHLYEKWSAELDFAVPTFEQFWRDGSLRLPTEPGLTLL
GDFRADPVAHRLGTPSGRIEIFSEDIAGFGYADCAGHPTWFEPTEWLGGERAATYPLHLVANQPATRLHGQLDGGSTSQS
AKVVGREAIRMHPDDAAARGVADGDVVRVFNDRGACLAGAVIDDRLRRSVVQLPTGAWFDPADPADYDAMCVHGNPNVLT
DDVGTSSLARGSTGAHVLVQVEKFSGPIPPVRAHEPPVIRQR
>Mature_761_residues
PARPTSLTHWGGFSAEVSSGDIAAVTPLPGDDDPSPLLGNLPGSVRHRSRIAGPAIRRGWLDDGPGPSRRRGADEFVAVS
WDELTDLLAAELRRVVDTHGNEAIYGGSYGWASAGRFHHAQSQVHRFLKLLGGYTYSRHSYSLGATGVIMPRVVGTHDDL
FKRSTDWDVIAARTDLLVCFGGLAMKNTGTNHGGTTAHPARAALRRFRGRGGRIVSFSPLRDDVDGECDWYAPVPGTDVA
IMLGLAYVLATERLADRGFLETHCVGYDRFERYLLGADDGVAKSPQWAAAICGLPADEITALARRMAAQRTIVTVSWSLQ
RVRHGEQAPWMGLTLAAMLGQIGLPGGGFGHGYGSMNEPGLPPLRCGLPRLPQGINPVSTFIPVAAVSDMLLHPGETFDY
NGMRLTYPDIRCVYWAGGNPFHHHQNIPRLRRALARVDTVVVHDPYWTAMAKHADIVVPSTTAFEREDYSGSKNDPVLMA
MPKLVEPYADSRDDYTTFAALADRLGFGEQFTEGRTARQWLAHLYEKWSAELDFAVPTFEQFWRDGSLRLPTEPGLTLLG
DFRADPVAHRLGTPSGRIEIFSEDIAGFGYADCAGHPTWFEPTEWLGGERAATYPLHLVANQPATRLHGQLDGGSTSQSA
KVVGREAIRMHPDDAAARGVADGDVVRVFNDRGACLAGAVIDDRLRRSVVQLPTGAWFDPADPADYDAMCVHGNPNVLTD
DVGTSSLARGSTGAHVLVQVEKFSGPIPPVRAHEPPVIRQR

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=776, Percent_Identity=38.7886597938144, Blast_Score=540, Evalue=1e-154,
Organism=Escherichia coli, GI145693196, Length=768, Percent_Identity=39.0625, Blast_Score=513, Evalue=1e-146,
Organism=Escherichia coli, GI1787231, Length=778, Percent_Identity=38.1748071979434, Blast_Score=492, Evalue=1e-140,
Organism=Escherichia coli, GI87081797, Length=781, Percent_Identity=30.9859154929577, Blast_Score=276, Evalue=5e-75,
Organism=Escherichia coli, GI1787870, Length=748, Percent_Identity=30.8823529411765, Blast_Score=261, Evalue=1e-70,
Organism=Escherichia coli, GI171474008, Length=746, Percent_Identity=29.8927613941019, Blast_Score=246, Evalue=4e-66,
Organism=Escherichia coli, GI3868721, Length=647, Percent_Identity=21.3292117465224, Blast_Score=109, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.7.2.3 [C]

Molecular weight: Translated: 82844; Mature: 82713

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARPTSLTHWGGFSAEVSSGDIAAVTPLPGDDDPSPLLGNLPGSVRHRSRIAGPAIRRG
CCCCCCCCEECCCCCEEECCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHCC
WLDDGPGPSRRRGADEFVAVSWDELTDLLAAELRRVVDTHGNEAIYGGSYGWASAGRFHH
CCCCCCCCCHHCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHH
AQSQVHRFLKLLGGYTYSRHSYSLGATGVIMPRVVGTHDDLFKRSTDWDVIAARTDLLVC
HHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCEECCCHHHHHCCCCCEEEEHHHCEEEE
FGGLAMKNTGTNHGGTTAHPARAALRRFRGRGGRIVSFSPLRDDVDGECDWYAPVPGTDV
ECCEEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCCCHH
AIMLGLAYVLATERLADRGFLETHCVGYDRFERYLLGADDGVAKSPQWAAAICGLPADEI
HHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHEECCCCCCCCCCCHHHHHHCCCHHHH
TALARRMAAQRTIVTVSWSLQRVRHGEQAPWMGLTLAAMLGQIGLPGGGFGHGYGSMNEP
HHHHHHHHHHCEEEEEEHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GLPPLRCGLPRLPQGINPVSTFIPVAAVSDMLLHPGETFDYNGMRLTYPDIRCVYWAGGN
CCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEECCCC
PFHHHQNIPRLRRALARVDTVVVHDPYWTAMAKHADIVVPSTTAFEREDYSGSKNDPVLM
CCHHCCCCHHHHHHHHHHCEEEEECCHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCEEE
AMPKLVEPYADSRDDYTTFAALADRLGFGEQFTEGRTARQWLAHLYEKWSAELDFAVPTF
ECHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCH
EQFWRDGSLRLPTEPGLTLLGDFRADPVAHRLGTPSGRIEIFSEDIAGFGYADCAGHPTW
HHHHCCCCEECCCCCCCEEEECCCCCHHHHHCCCCCCCEEEEECCCCCCCCHHCCCCCCC
FEPTEWLGGERAATYPLHLVANQPATRLHGQLDGGSTSQSAKVVGREAIRMHPDDAAARG
CCCHHHCCCCCCCCCEEEEEECCCHHHHCCCCCCCCCCCHHHHHHHHHHEECCCHHHHCC
VADGDVVRVFNDRGACLAGAVIDDRLRRSVVQLPTGAWFDPADPADYDAMCVHGNPNVLT
CCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEE
DDVGTSSLARGSTGAHVLVQVEKFSGPIPPVRAHEPPVIRQR
CCCCCHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PARPTSLTHWGGFSAEVSSGDIAAVTPLPGDDDPSPLLGNLPGSVRHRSRIAGPAIRRG
CCCCCCCEECCCCCEEECCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHCC
WLDDGPGPSRRRGADEFVAVSWDELTDLLAAELRRVVDTHGNEAIYGGSYGWASAGRFHH
CCCCCCCCCHHCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHH
AQSQVHRFLKLLGGYTYSRHSYSLGATGVIMPRVVGTHDDLFKRSTDWDVIAARTDLLVC
HHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCEECCCHHHHHCCCCCEEEEHHHCEEEE
FGGLAMKNTGTNHGGTTAHPARAALRRFRGRGGRIVSFSPLRDDVDGECDWYAPVPGTDV
ECCEEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCCCHH
AIMLGLAYVLATERLADRGFLETHCVGYDRFERYLLGADDGVAKSPQWAAAICGLPADEI
HHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHEECCCCCCCCCCCHHHHHHCCCHHHH
TALARRMAAQRTIVTVSWSLQRVRHGEQAPWMGLTLAAMLGQIGLPGGGFGHGYGSMNEP
HHHHHHHHHHCEEEEEEHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GLPPLRCGLPRLPQGINPVSTFIPVAAVSDMLLHPGETFDYNGMRLTYPDIRCVYWAGGN
CCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEECCCC
PFHHHQNIPRLRRALARVDTVVVHDPYWTAMAKHADIVVPSTTAFEREDYSGSKNDPVLM
CCHHCCCCHHHHHHHHHHCEEEEECCHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCEEE
AMPKLVEPYADSRDDYTTFAALADRLGFGEQFTEGRTARQWLAHLYEKWSAELDFAVPTF
ECHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCH
EQFWRDGSLRLPTEPGLTLLGDFRADPVAHRLGTPSGRIEIFSEDIAGFGYADCAGHPTW
HHHHCCCCEECCCCCCCEEEECCCCCHHHHHCCCCCCCEEEEECCCCCCCCHHCCCCCCC
FEPTEWLGGERAATYPLHLVANQPATRLHGQLDGGSTSQSAKVVGREAIRMHPDDAAARG
CCCHHHCCCCCCCCCEEEEEECCCHHHHCCCCCCCCCCCHHHHHHHHHHEECCCHHHHCC
VADGDVVRVFNDRGACLAGAVIDDRLRRSVVQLPTGAWFDPADPADYDAMCVHGNPNVLT
CCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEE
DDVGTSSLARGSTGAHVLVQVEKFSGPIPPVRAHEPPVIRQR
CCCCCHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds) [C]

Specific reaction: Reduces A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds), Back To Biotin. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8645727; 8534974; 7625833; 8658134 [H]