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The map label for this gene is yrbD [H]

Identifier: 119867947

GI number: 119867947

Start: 2025152

End: 2026690

Strand: Reverse

Name: yrbD [H]

Synonym: Mkms_1909

Alternate gene names: 119867947

Gene position: 2026690-2025152 (Counterclockwise)

Preceding gene: 119867948

Following gene: 119867939

Centisome position: 35.33

GC content: 66.93

Gene sequence:

>1539_bases
GTGTCCGAATTCCTCGACACGGTGAACGGCTTCGTGTGGAGCAACGCCCTGGTCTATCTGTGCCTGGGTGCAGGTGTGTA
CTTCTCGATCCGGTCGCGCTTCGTCCAGGTGCGCCAGGTGCCCGAGATGGTGCGGTTGATGTTGCGCGGCGAGAAGTCGC
CCTCCGGGGTCTCGTCGTTCCAGGCGCTGACGATGTCGCTGGCCGGCCGGGTCGGCACCGGCAACATCGCCGGCGTGGCG
ACGGCGATCGCGTTCGGTGGACCCGGCGCCCTGTTCTGGATGTGGGCGGTCGCGTTCCTCGGCGCCTCGACGTCCTTCGT
CGAGTGCACGCTGGGGCAGATCTACAAGACCCGCGACCCGTTGACCGGTGAATACCGCGGCGGGCCGGCCTACTACCTGA
GCCGGGCGCTCTCGCACACCGGCGCGGCGGGGCTCTTCAAGGTCTACGGCGCGATCTTCGCCGCCGTCACCGTCCTGGCG
TGCGGGCTGCTGCTGCCCAGCGTGCAGTCCAACTCGATGGCGTCGGCGATGAACTCAGCGTGGGGCTTCTCGACCTGGTG
GGTCGCGGTCGGCACGGTCATCGTGCTGGCGTTCGTCATCATCGGCGGCGTCAAGCGCATCGCGGCGTTCGCGTCGATCG
TGGTGCCGTTCATGGCGGTCGTCTACATCGTGCTCGCGCTGATCATCGTCCTTCTCAACGCCGGTGAGGTGCCCGGGATC
CTGCAGATGATCTTCGCCAGCGCCTTCGGTCTCGACTCCGCGTTCGGTGCGATCATCGGTTCCGCGGTGATGTGGGGTGT
CAAACGCGGCATCTACTCCAACGAGGCCGGACAGGGCACCGGTCCGCATGCGGCCGCCGCCGCGGAGGTGTCCCACCCCG
CCAAACAGGGTCTGGTCCAGGCGTTCGCGGTCTACGTCGACACGTTGTTCGTCTGCTCGGCCACCGGCTTCCTGATCCTG
TCGACCGGCGCCTACCGGGTGTTCGAGGGCGAGAGCGAAACCGGTGCGGTGCTCGCCGAGGGCGGCATGCTGCCCGCCGA
CACCCCGGTGGGGCCGGGCTTCGCGCAGGTCGGTTTCGACACGCTGTGGAGCGGGGCGGGCGCGTCGTTCGTGGCGATCT
CGTTGGCGTTCTTCTGTTTCACCACGTTGGTCGCCTACTACTACATGGCGGAGACGAACCTGCGGTTCATCCTCGGGAAG
TCCTCGACCGTGGAGATCCCGTTCATCCGCGGCACCGTCGGCGGGACCGCCACCATGCTGCTGCAGGCGCTGATCCTGGT
GTCGGTGGTGATCGGGGCGGTGTCGACGGCCACCGAGGCCTGGGTTCTCGGCGACATCGGCGTCGGGCTGATGGCCTGGC
TGAACATCATCGGCATCATCATCCTGCAGCAGCCCGCCTACAAGGCGCTGTGGGACTACGAGAAGCAGAAGAAGGCCGGG
CTGGATCCGCTGTTCGACCCGGTGGCGCTGCAGATCTCGAACGCCTCTTTCTGGGAGACGTACGAACCGACGCCGAGAAG
CCAGAAGTCCGCTGTCTAG

Upstream 100 bases:

>100_bases
GCCGAGGTGACCCTGATTTAACAAATATCGACCGTGAGGCGTGGAATCATGCCCGGGGGCCGCACAACGGCGGCCGACGT
ACGACGCGTGGGAGTGTGTG

Downstream 100 bases:

>100_bases
ACCGCCAGGATGGGAGCGAGCGCTGCCCGCGGCACCGACGCCTGGATGGCGCCCGCGGCCTCGGGCAGCAGTTCGCCCTG
GCCGAAGAAGAAGATCACCG

Product: amino acid carrier protein

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MSEFLDTVNGFVWSNALVYLCLGAGVYFSIRSRFVQVRQVPEMVRLMLRGEKSPSGVSSFQALTMSLAGRVGTGNIAGVA
TAIAFGGPGALFWMWAVAFLGASTSFVECTLGQIYKTRDPLTGEYRGGPAYYLSRALSHTGAAGLFKVYGAIFAAVTVLA
CGLLLPSVQSNSMASAMNSAWGFSTWWVAVGTVIVLAFVIIGGVKRIAAFASIVVPFMAVVYIVLALIIVLLNAGEVPGI
LQMIFASAFGLDSAFGAIIGSAVMWGVKRGIYSNEAGQGTGPHAAAAAEVSHPAKQGLVQAFAVYVDTLFVCSATGFLIL
STGAYRVFEGESETGAVLAEGGMLPADTPVGPGFAQVGFDTLWSGAGASFVAISLAFFCFTTLVAYYYMAETNLRFILGK
SSTVEIPFIRGTVGGTATMLLQALILVSVVIGAVSTATEAWVLGDIGVGLMAWLNIIGIIILQQPAYKALWDYEKQKKAG
LDPLFDPVALQISNASFWETYEPTPRSQKSAV

Sequences:

>Translated_512_residues
MSEFLDTVNGFVWSNALVYLCLGAGVYFSIRSRFVQVRQVPEMVRLMLRGEKSPSGVSSFQALTMSLAGRVGTGNIAGVA
TAIAFGGPGALFWMWAVAFLGASTSFVECTLGQIYKTRDPLTGEYRGGPAYYLSRALSHTGAAGLFKVYGAIFAAVTVLA
CGLLLPSVQSNSMASAMNSAWGFSTWWVAVGTVIVLAFVIIGGVKRIAAFASIVVPFMAVVYIVLALIIVLLNAGEVPGI
LQMIFASAFGLDSAFGAIIGSAVMWGVKRGIYSNEAGQGTGPHAAAAAEVSHPAKQGLVQAFAVYVDTLFVCSATGFLIL
STGAYRVFEGESETGAVLAEGGMLPADTPVGPGFAQVGFDTLWSGAGASFVAISLAFFCFTTLVAYYYMAETNLRFILGK
SSTVEIPFIRGTVGGTATMLLQALILVSVVIGAVSTATEAWVLGDIGVGLMAWLNIIGIIILQQPAYKALWDYEKQKKAG
LDPLFDPVALQISNASFWETYEPTPRSQKSAV
>Mature_511_residues
SEFLDTVNGFVWSNALVYLCLGAGVYFSIRSRFVQVRQVPEMVRLMLRGEKSPSGVSSFQALTMSLAGRVGTGNIAGVAT
AIAFGGPGALFWMWAVAFLGASTSFVECTLGQIYKTRDPLTGEYRGGPAYYLSRALSHTGAAGLFKVYGAIFAAVTVLAC
GLLLPSVQSNSMASAMNSAWGFSTWWVAVGTVIVLAFVIIGGVKRIAAFASIVVPFMAVVYIVLALIIVLLNAGEVPGIL
QMIFASAFGLDSAFGAIIGSAVMWGVKRGIYSNEAGQGTGPHAAAAAEVSHPAKQGLVQAFAVYVDTLFVCSATGFLILS
TGAYRVFEGESETGAVLAEGGMLPADTPVGPGFAQVGFDTLWSGAGASFVAISLAFFCFTTLVAYYYMAETNLRFILGKS
STVEIPFIRGTVGGTATMLLQALILVSVVIGAVSTATEAWVLGDIGVGLMAWLNIIGIIILQQPAYKALWDYEKQKKAGL
DPLFDPVALQISNASFWETYEPTPRSQKSAV

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=495, Percent_Identity=33.9393939393939, Blast_Score=261, Evalue=6e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 53898; Mature: 53767

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SEFLDTVNGFVWSNALVYLCLGAGVYFSIRSRFVQVRQVPEMVRLMLRGEKSPSGVSSF
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH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CCCCCCCCEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]