Click here to switch to the map view.

The map label for this gene is yisV [H]

Identifier: 119867939

GI number: 119867939

Start: 2017599

End: 2019035

Strand: Reverse

Name: yisV [H]

Synonym: Mkms_1901

Alternate gene names: 119867939

Gene position: 2019035-2017599 (Counterclockwise)

Preceding gene: 119867947

Following gene: 119867936

Centisome position: 35.19

GC content: 70.49

Gene sequence:

>1437_bases
ATGCCGACCAGAGTGCTCGACGTCGAGCGACTGGCACGTGAGTTGGGCAACTGGCGTACGGCCAGTTCGAGTGGCCCGGT
CTACCAGGGTCTGGCCGACGGAATCCGGATGCTGATCGTCGACGGGCGGTTACCGGTCGGCGCCCGCCTACCCAGTGAAC
GCGCACTCGCGGAGTGCCTGCGGGTTTCGCGCACCACCGTCACCAGCGCCTACGCCCAACTCCGCGAGGACGGCTATCTG
CTCGCCCGCCGCGGGGCGCGCAGCACCACGGCCCTGCCGGCCACACCGAACGCCGACACACCCCCGGCCGTTTCCCGCGG
TGCGGTCAACCTGGCCAATGCCGCGCTGGCCGCCCCTGTACCCGCGGTGCTCGCCGCCCTCACCGCCGCCACCGGCCAGA
TGGCGCCCTACCTGCACGACACCGGCATCGAACTCACCGGTGTCCCCTCGCTTCGCCGGGCCGTCGCCGAAAGATATTGT
GAGCGTGGGCTTCCCACCGAACCCGACGACATCATGATCACCACCGGGGCGCTGCACGCCATCGGGTTGATCCTGGCGAC
GTACACCCAGCCGGGAGATCGTGTCCTCGTCGAGCAGCCGACCTACCACGGCGCACTCGCCGCGATCTCCACCGCGGGCG
CCCGGGCGGTCCCCGTCGCGATCGGTGAGGACGGCTGGGATCTCGGGGCCTTGCACAACGCGGTCCGCCAGCTCGCGCCC
AGCCTCGCCTACGTGGTGCCCGACAACCACAACCCCACCGGTCTGACGATGCCGCAGCCCCAGCGCGAGGAGTTGGCCGC
GATGATCGCCGACACCCGCACCCGCACCATCGTCGACGAGACGATGACCGAGGTGTGGCTGGACGAGCCGGTCCCCCCTC
CGGTCGCCACGGCGATGACCCGCCGCCGCGATCTGCTGCTGACCATCGGGTCGATGTCCAAGTCGTTCTGGGGTGGTCTG
CGGATCGGCTGGATCCGCGCCGACCCGTCGACGTTGGCCTCGATCGCCGCGCTCCGCCCGTCCATCGACATGGGCACGCC
GATCCTCGAACAGCTCGCCGCCGCGGAGTTGATACGCGTCGCCGACGACGTGTTGCCGGAGCGACGCGAGATCCTGCGCA
CCCGCCGGGCACTGATGTTGTCGCTGCTCGACGAACATCTGCCGGATTGGCAGCCCTGCCCGGGTGGTGGCGGTCTGGCG
CTGTGGGTGCGACTGCCGACACCGATGAGTTCGGCCCTCTCGGCCGCGGCGTCACGGATGGGGCTGGACGTGCCGCCCGG
CCCGCGCTTCGGTGTGGACGGCTCGCTGGAGCGGTTCATCCGGATTCCCTACACGCTGCCGCCCGAGCAGATGACCGAGG
CCGTCACCCTGCTGGCGCGCGCCTGGCATGCGGTGACCGGTGCGACGGCTCCGCAGCAGCGTGTCGTAGTGGTATGA

Upstream 100 bases:

>100_bases
GAGTCGAGATATCCAGTTTGATGCCATGTGGCCATTCTTCGTACGACTGGCTTGCTCTTCAATAGCCAGTTGGCGCATAC
TGGCTGCAATGACGCTGGAA

Downstream 100 bases:

>100_bases
CCGAGTGGTATGACCGAGTGGTTTGATCGAGTGGTCTGACCACCGGGTGTAGCGGGTCAATCCTCGGGGATCTCGACGCG
GCGCAGCAGGCCGTCGACAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MPTRVLDVERLARELGNWRTASSSGPVYQGLADGIRMLIVDGRLPVGARLPSERALAECLRVSRTTVTSAYAQLREDGYL
LARRGARSTTALPATPNADTPPAVSRGAVNLANAALAAPVPAVLAALTAATGQMAPYLHDTGIELTGVPSLRRAVAERYC
ERGLPTEPDDIMITTGALHAIGLILATYTQPGDRVLVEQPTYHGALAAISTAGARAVPVAIGEDGWDLGALHNAVRQLAP
SLAYVVPDNHNPTGLTMPQPQREELAAMIADTRTRTIVDETMTEVWLDEPVPPPVATAMTRRRDLLLTIGSMSKSFWGGL
RIGWIRADPSTLASIAALRPSIDMGTPILEQLAAAELIRVADDVLPERREILRTRRALMLSLLDEHLPDWQPCPGGGGLA
LWVRLPTPMSSALSAAASRMGLDVPPGPRFGVDGSLERFIRIPYTLPPEQMTEAVTLLARAWHAVTGATAPQQRVVVV

Sequences:

>Translated_478_residues
MPTRVLDVERLARELGNWRTASSSGPVYQGLADGIRMLIVDGRLPVGARLPSERALAECLRVSRTTVTSAYAQLREDGYL
LARRGARSTTALPATPNADTPPAVSRGAVNLANAALAAPVPAVLAALTAATGQMAPYLHDTGIELTGVPSLRRAVAERYC
ERGLPTEPDDIMITTGALHAIGLILATYTQPGDRVLVEQPTYHGALAAISTAGARAVPVAIGEDGWDLGALHNAVRQLAP
SLAYVVPDNHNPTGLTMPQPQREELAAMIADTRTRTIVDETMTEVWLDEPVPPPVATAMTRRRDLLLTIGSMSKSFWGGL
RIGWIRADPSTLASIAALRPSIDMGTPILEQLAAAELIRVADDVLPERREILRTRRALMLSLLDEHLPDWQPCPGGGGLA
LWVRLPTPMSSALSAAASRMGLDVPPGPRFGVDGSLERFIRIPYTLPPEQMTEAVTLLARAWHAVTGATAPQQRVVVV
>Mature_477_residues
PTRVLDVERLARELGNWRTASSSGPVYQGLADGIRMLIVDGRLPVGARLPSERALAECLRVSRTTVTSAYAQLREDGYLL
ARRGARSTTALPATPNADTPPAVSRGAVNLANAALAAPVPAVLAALTAATGQMAPYLHDTGIELTGVPSLRRAVAERYCE
RGLPTEPDDIMITTGALHAIGLILATYTQPGDRVLVEQPTYHGALAAISTAGARAVPVAIGEDGWDLGALHNAVRQLAPS
LAYVVPDNHNPTGLTMPQPQREELAAMIADTRTRTIVDETMTEVWLDEPVPPPVATAMTRRRDLLLTIGSMSKSFWGGLR
IGWIRADPSTLASIAALRPSIDMGTPILEQLAAAELIRVADDVLPERREILRTRRALMLSLLDEHLPDWQPCPGGGGLAL
WVRLPTPMSSALSAAASRMGLDVPPGPRFGVDGSLERFIRIPYTLPPEQMTEAVTLLARAWHAVTGATAPQQRVVVV

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=320, Percent_Identity=23.125, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI33469970, Length=320, Percent_Identity=23.125, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1787710, Length=447, Percent_Identity=29.5302013422819, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1790797, Length=472, Percent_Identity=26.6949152542373, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788722, Length=327, Percent_Identity=23.8532110091743, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356535, Length=378, Percent_Identity=23.015873015873, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 51101; Mature: 50969

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50949 HTH_GNTR ; PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTRVLDVERLARELGNWRTASSSGPVYQGLADGIRMLIVDGRLPVGARLPSERALAECL
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHH
RVSRTTVTSAYAQLREDGYLLARRGARSTTALPATPNADTPPAVSRGAVNLANAALAAPV
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCH
PAVLAALTAATGQMAPYLHDTGIELTGVPSLRRAVAERYCERGLPTEPDDIMITTGALHA
HHHHHHHHHHCCCCCCCEECCCCEEECCHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHH
IGLILATYTQPGDRVLVEQPTYHGALAAISTAGARAVPVAIGEDGWDLGALHNAVRQLAP
HHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCC
SLAYVVPDNHNPTGLTMPQPQREELAAMIADTRTRTIVDETMTEVWLDEPVPPPVATAMT
CEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHHHH
RRRDLLLTIGSMSKSFWGGLRIGWIRADPSTLASIAALRPSIDMGTPILEQLAAAELIRV
HCCCEEEEECHHHHHHCCCEEEEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
ADDVLPERREILRTRRALMLSLLDEHLPDWQPCPGGGGLALWVRLPTPMSSALSAAASRM
HHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHC
GLDVPPGPRFGVDGSLERFIRIPYTLPPEQMTEAVTLLARAWHAVTGATAPQQRVVVV
CCCCCCCCCCCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEC
>Mature Secondary Structure 
PTRVLDVERLARELGNWRTASSSGPVYQGLADGIRMLIVDGRLPVGARLPSERALAECL
CCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHH
RVSRTTVTSAYAQLREDGYLLARRGARSTTALPATPNADTPPAVSRGAVNLANAALAAPV
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCH
PAVLAALTAATGQMAPYLHDTGIELTGVPSLRRAVAERYCERGLPTEPDDIMITTGALHA
HHHHHHHHHHCCCCCCCEECCCCEEECCHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHH
IGLILATYTQPGDRVLVEQPTYHGALAAISTAGARAVPVAIGEDGWDLGALHNAVRQLAP
HHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCC
SLAYVVPDNHNPTGLTMPQPQREELAAMIADTRTRTIVDETMTEVWLDEPVPPPVATAMT
CEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHHHH
RRRDLLLTIGSMSKSFWGGLRIGWIRADPSTLASIAALRPSIDMGTPILEQLAAAELIRV
HCCCEEEEECHHHHHHCCCEEEEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
ADDVLPERREILRTRRALMLSLLDEHLPDWQPCPGGGGLALWVRLPTPMSSALSAAASRM
HHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHC
GLDVPPGPRFGVDGSLERFIRIPYTLPPEQMTEAVTLLARAWHAVTGATAPQQRVVVV
CCCCCCCCCCCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]