| Definition | Mycobacterium sp. KMS chromosome, complete genome. |
|---|---|
| Accession | NC_008705 |
| Length | 5,737,227 |
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The map label for this gene is fabG [H]
Identifier: 119867907
GI number: 119867907
Start: 1982547
End: 1983344
Strand: Reverse
Name: fabG [H]
Synonym: Mkms_1869
Alternate gene names: 119867907
Gene position: 1983344-1982547 (Counterclockwise)
Preceding gene: 119867911
Following gene: 119867905
Centisome position: 34.57
GC content: 71.3
Gene sequence:
>798_bases ATGCCCACAGCAGTTCCGAACGCGTTCGATCTGACCGGTCAGGTGGCCCTGGTCACCGGGTCGAGCAGCGAGCTCGGGAT CGGCTTCGCCTCGGCACGTCTACTCGGACAGTTCGGGGCGTCGGTGATGGTCACCGGGACCACCGAGCGCGCCGCCGAAC GCGCGCGGGAACTGCAGAGTGAGGGCATCGCGGCGCGTTCGCACGTCGCGGACCTGATGGATCCGGAGGCGGCCCGGGGA CTGGTCGAGGCAACCGAGGCGGCGTTCGGCCGGCTCGACATCGTGGTCAACAACGCCGGGCTGGCGTCGGTGCACATCCC CGAGCGTCCGAATCCGTTGATGGTGATGTCCGACGAGGAATGGCGCCTGGCGCTGCGACGCAACGTGGACAGCGCGTTCT TCGTCACCCGGGCCGCCCTGCCCGGCATGGTGGAACGGGGCTACGGCCGCATCGTCAACGTGGCGTCGACGGCCGGGATC CTCACCGCCTACACCGGCGACGTCGGTTACCACACGGCCAAGGCCGCGATGCTGGGGATGACGCGGTCGGTGGCGGTGGA CTACGCGCGCAACGGCGTGACGGCCAACGTGGTGGTCCCCGGCTGGATCGCCACCGCGGCGCAGCTCCCCTCCGAGGTGG TCGCGGGCAACGCGACGCCGATCGGCCGGTCGGCCACCGCGGCCGAGGTCGCCGCAGGCATCGCGTTCCTCGCGGCGCCG GGCGCCTCCTACGTCACGGGCACCACGTTGGCCATCGACGGCGCCAACTCGATCGCGGGGTCGTCGGCGACCGAGTGA
Upstream 100 bases:
>100_bases TTGTACGAACGTCCAAGTTTTGGTCGGTTGACCTAGCAGGGTCCCGCAACGCGCTCTAGTGTTCTGGCACAGCATGCGAA AGACGAAGGGAAACAACACA
Downstream 100 bases:
>100_bases CACGGACGGCGCCTGGCGATCGGATCCCGCCCCGCCCCACTCGACTGTGCGGTTTCATCCGCGCCACGCCGGGGCAGGCG TATCGGAACGCACACTCGAT
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 265; Mature: 264
Protein sequence:
>265_residues MPTAVPNAFDLTGQVALVTGSSSELGIGFASARLLGQFGASVMVTGTTERAAERARELQSEGIAARSHVADLMDPEAARG LVEATEAAFGRLDIVVNNAGLASVHIPERPNPLMVMSDEEWRLALRRNVDSAFFVTRAALPGMVERGYGRIVNVASTAGI LTAYTGDVGYHTAKAAMLGMTRSVAVDYARNGVTANVVVPGWIATAAQLPSEVVAGNATPIGRSATAAEVAAGIAFLAAP GASYVTGTTLAIDGANSIAGSSATE
Sequences:
>Translated_265_residues MPTAVPNAFDLTGQVALVTGSSSELGIGFASARLLGQFGASVMVTGTTERAAERARELQSEGIAARSHVADLMDPEAARG LVEATEAAFGRLDIVVNNAGLASVHIPERPNPLMVMSDEEWRLALRRNVDSAFFVTRAALPGMVERGYGRIVNVASTAGI LTAYTGDVGYHTAKAAMLGMTRSVAVDYARNGVTANVVVPGWIATAAQLPSEVVAGNATPIGRSATAAEVAAGIAFLAAP GASYVTGTTLAIDGANSIAGSSATE >Mature_264_residues PTAVPNAFDLTGQVALVTGSSSELGIGFASARLLGQFGASVMVTGTTERAAERARELQSEGIAARSHVADLMDPEAARGL VEATEAAFGRLDIVVNNAGLASVHIPERPNPLMVMSDEEWRLALRRNVDSAFFVTRAALPGMVERGYGRIVNVASTAGIL TAYTGDVGYHTAKAAMLGMTRSVAVDYARNGVTANVVVPGWIATAAQLPSEVVAGNATPIGRSATAAEVAAGIAFLAAPG ASYVTGTTLAIDGANSIAGSSATE
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=33.5907335907336, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=31.7647058823529, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI5031737, Length=261, Percent_Identity=32.9501915708812, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI66933014, Length=231, Percent_Identity=30.3030303030303, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI19923817, Length=265, Percent_Identity=27.9245283018868, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI4504505, Length=221, Percent_Identity=32.579185520362, Blast_Score=88, Evalue=6e-18, Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=30.7377049180328, Blast_Score=86, Evalue=5e-17, Organism=Homo sapiens, GI59889578, Length=226, Percent_Identity=31.858407079646, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI33667109, Length=203, Percent_Identity=34.4827586206897, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI126723191, Length=193, Percent_Identity=33.160621761658, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI10190704, Length=262, Percent_Identity=29.3893129770992, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI126723750, Length=257, Percent_Identity=28.4046692607004, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI7706318, Length=199, Percent_Identity=29.1457286432161, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI31542939, Length=204, Percent_Identity=29.9019607843137, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI210032110, Length=200, Percent_Identity=27, Blast_Score=70, Evalue=3e-12, Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=36.4, Blast_Score=140, Evalue=1e-34, Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=33.8461538461538, Blast_Score=135, Evalue=2e-33, Organism=Escherichia coli, GI1789208, Length=262, Percent_Identity=30.1526717557252, Blast_Score=110, Evalue=7e-26, Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=34.6456692913386, Blast_Score=110, Evalue=9e-26, Organism=Escherichia coli, GI1790717, Length=262, Percent_Identity=29.7709923664122, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=25.8823529411765, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1789378, Length=257, Percent_Identity=30.7392996108949, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1787820, Length=189, Percent_Identity=32.8042328042328, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=32.4, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1787905, Length=259, Percent_Identity=30.5019305019305, Blast_Score=75, Evalue=6e-15, Organism=Escherichia coli, GI1786812, Length=266, Percent_Identity=28.1954887218045, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=31.8725099601594, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1789057, Length=265, Percent_Identity=25.2830188679245, Blast_Score=64, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17560676, Length=259, Percent_Identity=33.5907335907336, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=34.7014925373134, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=32.2097378277154, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=35.5555555555556, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=30.7086614173228, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=35.5555555555556, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=31.7164179104478, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI193204405, Length=276, Percent_Identity=31.8840579710145, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI71994600, Length=259, Percent_Identity=32.4324324324324, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=32.8413284132841, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17551412, Length=274, Percent_Identity=31.3868613138686, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17544670, Length=279, Percent_Identity=31.1827956989247, Blast_Score=95, Evalue=5e-20, Organism=Caenorhabditis elegans, GI71994604, Length=261, Percent_Identity=32.5670498084291, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI193203115, Length=246, Percent_Identity=30.8943089430894, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=29.6296296296296, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17561402, Length=270, Percent_Identity=29.2592592592593, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=29.8507462686567, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17560220, Length=272, Percent_Identity=32.7205882352941, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17568967, Length=199, Percent_Identity=33.1658291457286, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI193203117, Length=245, Percent_Identity=30.6122448979592, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17565030, Length=267, Percent_Identity=31.8352059925094, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=29.8507462686567, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=30.8, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562990, Length=269, Percent_Identity=28.996282527881, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI72000259, Length=269, Percent_Identity=28.996282527881, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17564282, Length=255, Percent_Identity=27.843137254902, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=28.6245353159851, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=30.859375, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17508895, Length=210, Percent_Identity=25.2380952380952, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17555612, Length=208, Percent_Identity=29.3269230769231, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=204, Percent_Identity=24.5098039215686, Blast_Score=70, Evalue=4e-13, Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=34.6456692913386, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=35.1778656126482, Blast_Score=107, Evalue=8e-24, Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=30.6201550387597, Blast_Score=104, Evalue=6e-23, Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=33.59375, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI18859837, Length=195, Percent_Identity=35.3846153846154, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=32.6848249027237, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI24644339, Length=261, Percent_Identity=31.4176245210728, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24644337, Length=270, Percent_Identity=32.2222222222222, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24640492, Length=202, Percent_Identity=27.7227722772277, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI17737361, Length=211, Percent_Identity=33.175355450237, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI21357673, Length=205, Percent_Identity=26.8292682926829, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24643142, Length=256, Percent_Identity=26.5625, Blast_Score=66, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 27032; Mature: 26901
Theoretical pI: Translated: 4.87; Mature: 4.87
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPTAVPNAFDLTGQVALVTGSSSELGIGFASARLLGQFGASVMVTGTTERAAERARELQS CCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHH EGIAARSHVADLMDPEAARGLVEATEAAFGRLDIVVNNAGLASVHIPERPNPLMVMSDEE CCCHHHHHHHHHCCHHHHHHHHHHHHHHHCEEEEEEECCCEEEEECCCCCCCEEEECCCH WRLALRRNVDSAFFVTRAALPGMVERGYGRIVNVASTAGILTAYTGDVGYHTAKAAMLGM HHHHHHHCCCHHHHHHHHHCCHHHHCCCCCEEEECHHCCEEEEEECCCCHHHHHHHHHHH TRSVAVDYARNGVTANVVVPGWIATAAQLPSEVVAGNATPIGRSATAAEVAAGIAFLAAP HHHHHHHHHCCCEEEEEEECCHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHEEECC GASYVTGTTLAIDGANSIAGSSATE CCCCEECEEEEEECCCCCCCCCCCC >Mature Secondary Structure PTAVPNAFDLTGQVALVTGSSSELGIGFASARLLGQFGASVMVTGTTERAAERARELQS CCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHH EGIAARSHVADLMDPEAARGLVEATEAAFGRLDIVVNNAGLASVHIPERPNPLMVMSDEE CCCHHHHHHHHHCCHHHHHHHHHHHHHHHCEEEEEEECCCEEEEECCCCCCCEEEECCCH WRLALRRNVDSAFFVTRAALPGMVERGYGRIVNVASTAGILTAYTGDVGYHTAKAAMLGM HHHHHHHCCCHHHHHHHHHCCHHHHCCCCCEEEECHHCCEEEEEECCCCHHHHHHHHHHH TRSVAVDYARNGVTANVVVPGWIATAAQLPSEVVAGNATPIGRSATAAEVAAGIAFLAAP HHHHHHHHHCCCEEEEEEECCHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHEEECC GASYVTGTTLAIDGANSIAGSSATE CCCCEECEEEEEECCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7542800 [H]