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The map label for this gene is paaG [H]

Identifier: 119867852

GI number: 119867852

Start: 1924163

End: 1924981

Strand: Reverse

Name: paaG [H]

Synonym: Mkms_1813

Alternate gene names: 119867852

Gene position: 1924981-1924163 (Counterclockwise)

Preceding gene: 119867856

Following gene: 119867851

Centisome position: 33.55

GC content: 69.6

Gene sequence:

>819_bases
GTGGGGCAACAGGGCGGCACGGCCGCACCGGACGGGTCGGTGTCCGTGCACCGCGAGGACGCCGCACTGGTGCTGACCCT
GGACCGGCCCCAGCGCCGAAACTCGCTGAGTCACATGATGATCGACGAACTCGTCACCGCCCTGACCGCAGCGGCGACCG
ATGATTCACTGCGGGTCGTGCACATCCGCGGCGCGGGCGGGGACTTCTGCACCGGCGCCGACTGGGTGGCGACCAACACC
GCGGGTCAGCGTCCCCGAACCGGTGATCTGGTGCGACGGATCCCGCACGGTGCGAACCGGGTGGTCGAACTGGTGCACAC
GTTGCACCTGCCGGTGGTCTGCAGTGTGCAGGGCTGGGCGGTGGGCCTCGGGTGCAATCTGGCGCTGGCCGCCGACTTCA
CCGTCGCCGGCACCGACGCGGTGTTCTGGGAACCCTTTGTGGAGCGCGGTTTCGCACCGGACTCCGGGGCCAGTTGGCTG
CTGCCCCGCCTGGTGGGCCTGGCGCGGACCAAACGCATGCTGCTGCTCGGCGAGAAGGTCAGCGGCGCCGAGGCCGCCGA
ATGGGGGTTGATCCACGACAGTGTGCCGGGCGACGAGGTCGCCGCGGCCGCCGACCGGCTGGTGGCACGCCTGGCCGCCG
GGCCCACGGTCGCGATCGGCCTGGCCAAACAGGCCGTGCACCAGGCGTTGCACACGCCACTCGCCCAGGCCATGACACAG
GAATTGTTCAACGTCGAACTCTCCTGTCGTACAGCGGATTTCAAAGAGGGTCTGGCCGCGTTCCGAGACAAGCGCGACCC
GGACTTCCAAGGCCGATGA

Upstream 100 bases:

>100_bases
CCTGTTTCGTCGAGGTGGATTTCGCTATGTTGTACGGAGCACGAATCGTATCGCCTACTGTAGGGCTAACCATAACGACA
GCGGAAGGGCGGGTGCGCCG

Downstream 100 bases:

>100_bases
CCCCCGACCACACCATCGAGGAGCGCGGATGACCGACAGTTCGTACGACACGATCAAATACGAGGTCGACGGACACACCG
CGACCATCACGCTGAACCGG

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MGQQGGTAAPDGSVSVHREDAALVLTLDRPQRRNSLSHMMIDELVTALTAAATDDSLRVVHIRGAGGDFCTGADWVATNT
AGQRPRTGDLVRRIPHGANRVVELVHTLHLPVVCSVQGWAVGLGCNLALAADFTVAGTDAVFWEPFVERGFAPDSGASWL
LPRLVGLARTKRMLLLGEKVSGAEAAEWGLIHDSVPGDEVAAAADRLVARLAAGPTVAIGLAKQAVHQALHTPLAQAMTQ
ELFNVELSCRTADFKEGLAAFRDKRDPDFQGR

Sequences:

>Translated_272_residues
MGQQGGTAAPDGSVSVHREDAALVLTLDRPQRRNSLSHMMIDELVTALTAAATDDSLRVVHIRGAGGDFCTGADWVATNT
AGQRPRTGDLVRRIPHGANRVVELVHTLHLPVVCSVQGWAVGLGCNLALAADFTVAGTDAVFWEPFVERGFAPDSGASWL
LPRLVGLARTKRMLLLGEKVSGAEAAEWGLIHDSVPGDEVAAAADRLVARLAAGPTVAIGLAKQAVHQALHTPLAQAMTQ
ELFNVELSCRTADFKEGLAAFRDKRDPDFQGR
>Mature_271_residues
GQQGGTAAPDGSVSVHREDAALVLTLDRPQRRNSLSHMMIDELVTALTAAATDDSLRVVHIRGAGGDFCTGADWVATNTA
GQRPRTGDLVRRIPHGANRVVELVHTLHLPVVCSVQGWAVGLGCNLALAADFTVAGTDAVFWEPFVERGFAPDSGASWLL
PRLVGLARTKRMLLLGEKVSGAEAAEWGLIHDSVPGDEVAAAADRLVARLAAGPTVAIGLAKQAVHQALHTPLAQAMTQE
LFNVELSCRTADFKEGLAAFRDKRDPDFQGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=250, Percent_Identity=28, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI4757968, Length=240, Percent_Identity=28.3333333333333, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI49355787, Length=240, Percent_Identity=28.3333333333333, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI4757966, Length=232, Percent_Identity=28.0172413793103, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI51538581, Length=232, Percent_Identity=28.0172413793103, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI25453481, Length=232, Percent_Identity=28.0172413793103, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI51538573, Length=232, Percent_Identity=28.0172413793103, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI45643119, Length=219, Percent_Identity=26.4840182648402, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI260275230, Length=219, Percent_Identity=26.4840182648402, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI31542718, Length=248, Percent_Identity=27.8225806451613, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI260274832, Length=219, Percent_Identity=26.4840182648402, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4502327, Length=255, Percent_Identity=30.5882352941176, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI150378541, Length=253, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI221136756, Length=233, Percent_Identity=28.3261802575107, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI221136753, Length=233, Percent_Identity=28.3261802575107, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI221307494, Length=222, Percent_Identity=28.8288288288288, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI70995211, Length=203, Percent_Identity=27.5862068965517, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI68989263, Length=210, Percent_Identity=28.0952380952381, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI116235487, Length=211, Percent_Identity=25.1184834123223, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI157694516, Length=238, Percent_Identity=25.2100840336134, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI213417737, Length=238, Percent_Identity=25.2100840336134, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787660, Length=258, Percent_Identity=37.984496124031, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1787659, Length=257, Percent_Identity=35.408560311284, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI221142681, Length=264, Percent_Identity=30.6818181818182, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788597, Length=262, Percent_Identity=28.6259541984733, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788682, Length=197, Percent_Identity=27.9187817258883, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790281, Length=186, Percent_Identity=25.8064516129032, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17554946, Length=259, Percent_Identity=29.3436293436293, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17540714, Length=240, Percent_Identity=28.3333333333333, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25145438, Length=251, Percent_Identity=28.2868525896414, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17535521, Length=223, Percent_Identity=26.457399103139, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17549921, Length=214, Percent_Identity=26.6355140186916, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17560910, Length=218, Percent_Identity=25.6880733944954, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25144157, Length=206, Percent_Identity=28.1553398058252, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25144160, Length=206, Percent_Identity=28.1553398058252, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17534483, Length=178, Percent_Identity=27.5280898876405, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=196, Percent_Identity=26.530612244898, Blast_Score=76, Evalue=5e-15,
Organism=Drosophila melanogaster, GI20129971, Length=248, Percent_Identity=30.6451612903226, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24653477, Length=248, Percent_Identity=30.6451612903226, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24653139, Length=279, Percent_Identity=30.8243727598566, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21357171, Length=270, Percent_Identity=27.7777777777778, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19922422, Length=262, Percent_Identity=24.8091603053435, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24654903, Length=255, Percent_Identity=21.1764705882353, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24650670, Length=261, Percent_Identity=27.2030651340996, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI19920382, Length=250, Percent_Identity=27.6, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28863; Mature: 28732

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQQGGTAAPDGSVSVHREDAALVLTLDRPQRRNSLSHMMIDELVTALTAAATDDSLRVV
CCCCCCCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
HIRGAGGDFCTGADWVATNTAGQRPRTGDLVRRIPHGANRVVELVHTLHLPVVCSVQGWA
EEECCCCCCCCCCCEEEECCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCEE
VGLGCNLALAADFTVAGTDAVFWEPFVERGFAPDSGASWLLPRLVGLARTKRMLLLGEKV
EEECCCEEEEECEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCC
SGAEAAEWGLIHDSVPGDEVAAAADRLVARLAAGPTVAIGLAKQAVHQALHTPLAQAMTQ
CCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELFNVELSCRTADFKEGLAAFRDKRDPDFQGR
HHHCEEEEEECCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
GQQGGTAAPDGSVSVHREDAALVLTLDRPQRRNSLSHMMIDELVTALTAAATDDSLRVV
CCCCCCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
HIRGAGGDFCTGADWVATNTAGQRPRTGDLVRRIPHGANRVVELVHTLHLPVVCSVQGWA
EEECCCCCCCCCCCEEEECCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCEE
VGLGCNLALAADFTVAGTDAVFWEPFVERGFAPDSGASWLLPRLVGLARTKRMLLLGEKV
EEECCCEEEEECEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCC
SGAEAAEWGLIHDSVPGDEVAAAADRLVARLAAGPTVAIGLAKQAVHQALHTPLAQAMTQ
CCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELFNVELSCRTADFKEGLAAFRDKRDPDFQGR
HHHCEEEEEECCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]