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The map label for this gene is nisX1 [H]

Identifier: 119867697

GI number: 119867697

Start: 1768213

End: 1769112

Strand: Reverse

Name: nisX1 [H]

Synonym: Mkms_1652

Alternate gene names: 119867697

Gene position: 1769112-1768213 (Counterclockwise)

Preceding gene: 119867698

Following gene: 119867691

Centisome position: 30.84

GC content: 65.44

Gene sequence:

>900_bases
GTGAGCCGCTTTCAGTTTGTCGCCGACCACCTGCACGCCTTCGAGGTGAAGTGGCTCTGCGCAGTCGTCGAGGTTGCGCG
TTCGTCGTTCTACGCGTGGTTGGCCGGTGCTGACGGACGAGCGGCCCGTCGGGCTGCTGACGAGGCGCTGGCCGAGCGTA
TCCGCGCCGTCCACGACGAGGACAACACCTACGGGGCGCCGCGGATCACCGCCGAGCTCAACGACGGTGCGCCCGAGGGG
CAGCGGGTCAACCACAAGCGGGTGGCTCGGGTGATGCGCGGCGCCGGGATCGCCGGTTATCGACGCCGACGTCGGGTCAA
GACGACCGTGGCGGACCCGGCGAACCAGAAGGTCCCCGACCTGCTCAAACGCGATTTCACCGCCGCGCAGGTCAACACCC
GTTACGTCGGCGACATCACCTACTTGCCATTGGCGACCGGCGCCAACCTGTACCTGGCCACCGTGATCGACTGCTGTTCA
CGGCGGGTCGCCGGGTGGGCGATCGCCGATCACATGCGCACCGAACTGGTCATCGATGCGCTCAAAGCCGCTGCTGCACT
GCGGGGTTCACTGGCTGGTGCAATATTCCATGCAGATCATGGAAGTCAGTACACCTCACGGGATTTCGCGAATCTCTGCC
GCGATCTGGGGGTCGTCCAGTCGATGGGTGCGGTGGGGTCAAGTGCCGATAACGCGTTGGCCGAATCGTTCAACGCCGCC
CTCAAGCGCGAGATTCTGCAAGACCGTGCCTGCTGGCCGGACGCGGCGATCTGCCGCCGTGAGGTCTTTCGGTGGCTGGC
CCGCTACAACACCACACGACGGCACTCCTACTGCCGTCATTCCAGCCCCGCGACCTACGAAAGGAACCTGACACCGGCTA
CGCTGCCCGAAGCCGCATAA

Upstream 100 bases:

>100_bases
GCAGTGAGGTCAAGGCGTTACGCGCCACCGAGGCGCGGTTGTCCACCGAGCGTGACATCTTGCGGTCGGCGGCCAAATAT
TTCGCCGGGGAGACGAACTG

Downstream 100 bases:

>100_bases
CCACAAATCCCGTGTCCACTACATGGGGGCAAGGCCCCTGAGCTGACCTCTTGGGTCAGTACCCCTAACGGGGCGAAAGC
TCGAGATATGCAGCACGCTA

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSRFQFVADHLHAFEVKWLCAVVEVARSSFYAWLAGADGRAARRAADEALAERIRAVHDEDNTYGAPRITAELNDGAPEG
QRVNHKRVARVMRGAGIAGYRRRRRVKTTVADPANQKVPDLLKRDFTAAQVNTRYVGDITYLPLATGANLYLATVIDCCS
RRVAGWAIADHMRTELVIDALKAAAALRGSLAGAIFHADHGSQYTSRDFANLCRDLGVVQSMGAVGSSADNALAESFNAA
LKREILQDRACWPDAAICRREVFRWLARYNTTRRHSYCRHSSPATYERNLTPATLPEAA

Sequences:

>Translated_299_residues
MSRFQFVADHLHAFEVKWLCAVVEVARSSFYAWLAGADGRAARRAADEALAERIRAVHDEDNTYGAPRITAELNDGAPEG
QRVNHKRVARVMRGAGIAGYRRRRRVKTTVADPANQKVPDLLKRDFTAAQVNTRYVGDITYLPLATGANLYLATVIDCCS
RRVAGWAIADHMRTELVIDALKAAAALRGSLAGAIFHADHGSQYTSRDFANLCRDLGVVQSMGAVGSSADNALAESFNAA
LKREILQDRACWPDAAICRREVFRWLARYNTTRRHSYCRHSSPATYERNLTPATLPEAA
>Mature_298_residues
SRFQFVADHLHAFEVKWLCAVVEVARSSFYAWLAGADGRAARRAADEALAERIRAVHDEDNTYGAPRITAELNDGAPEGQ
RVNHKRVARVMRGAGIAGYRRRRRVKTTVADPANQKVPDLLKRDFTAAQVNTRYVGDITYLPLATGANLYLATVIDCCSR
RVAGWAIADHMRTELVIDALKAAAALRGSLAGAIFHADHGSQYTSRDFANLCRDLGVVQSMGAVGSSADNALAESFNAAL
KREILQDRACWPDAAICRREVFRWLARYNTTRRHSYCRHSSPATYERNLTPATLPEAA

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=262, Percent_Identity=34.3511450381679, Blast_Score=132, Evalue=3e-31,
Organism=Escherichia coli, GI1788405, Length=291, Percent_Identity=34.020618556701, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1787263, Length=291, Percent_Identity=34.020618556701, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1786753, Length=291, Percent_Identity=34.020618556701, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1786570, Length=291, Percent_Identity=34.020618556701, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1786490, Length=291, Percent_Identity=34.020618556701, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1789981, Length=274, Percent_Identity=28.1021897810219, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790724, Length=266, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789424, Length=266, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789224, Length=266, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788305, Length=266, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787669, Length=266, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786558, Length=266, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 33032; Mature: 32900

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFQFVADHLHAFEVKWLCAVVEVARSSFYAWLAGADGRAARRAADEALAERIRAVHDE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHCCC
DNTYGAPRITAELNDGAPEGQRVNHKRVARVMRGAGIAGYRRRRRVKTTVADPANQKVPD
CCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHH
LLKRDFTAAQVNTRYVGDITYLPLATGANLYLATVIDCCSRRVAGWAIADHMRTELVIDA
HHHHCCHHHHCCCEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKAAAALRGSLAGAIFHADHGSQYTSRDFANLCRDLGVVQSMGAVGSSADNALAESFNAA
HHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LKREILQDRACWPDAAICRREVFRWLARYNTTRRHSYCRHSSPATYERNLTPATLPEAA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEECCCCCCCCCCCC
>Mature Secondary Structure 
SRFQFVADHLHAFEVKWLCAVVEVARSSFYAWLAGADGRAARRAADEALAERIRAVHDE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHCCC
DNTYGAPRITAELNDGAPEGQRVNHKRVARVMRGAGIAGYRRRRRVKTTVADPANQKVPD
CCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHH
LLKRDFTAAQVNTRYVGDITYLPLATGANLYLATVIDCCSRRVAGWAIADHMRTELVIDA
HHHHCCHHHHCCCEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKAAAALRGSLAGAIFHADHGSQYTSRDFANLCRDLGVVQSMGAVGSSADNALAESFNAA
HHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LKREILQDRACWPDAAICRREVFRWLARYNTTRRHSYCRHSSPATYERNLTPATLPEAA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1482189; 11337471; 1482192 [H]