Click here to switch to the map view.

The map label for this gene is nuoC

Identifier: 119867648

GI number: 119867648

Start: 1721129

End: 1721824

Strand: Reverse

Name: nuoC

Synonym: Mkms_1602

Alternate gene names: 119867648

Gene position: 1721824-1721129 (Counterclockwise)

Preceding gene: 119867649

Following gene: 119867647

Centisome position: 30.01

GC content: 69.83

Gene sequence:

>696_bases
GTGACGGAGGCGAACGGCACCACCGGGGGCGGCGCGGGCGATCCGGAAGTCATCGACGTGCGCCGAGGGATGTTCGGGGC
CAAGGGTTCTGGCGACACGTCGGGTTACGGCAGGCTGATCCGGTCGGTGGCGCTGCCCGGCGGTTCACCGCGGCCGTACG
GCGGCCACTTCGACGAGGTCGTCGACGCGCTGGCGGCCGCGCTGGGCCAAGACCTGTACGACGCATCGGTCGAACGCATC
GTCGTCTACCGCGACGAACTGACGCTCGAGATCGCCCGGGCCCGACTGCCCGTCGTCGCCAAGACCCTGCGTGACGACGC
GGCCCTGCGGTTCGAACTGTGCCTCGGGGTCAGCGGCGTGCACTACCCGGGCGACGCCGGGCGCGAACTGCACGCCGCGT
ACCCGCTGATGTCGATCACCCACAACCGGCGGATCCGGCTGGAAGTGGCCGCCCCCGACGACGATCCGCACATCCCGTCG
CTGTTCTCGGTGTACCCCACCACCGACTGGCACGAGCGGGAGACCTACGACTTCTTCGGGATCATCTTCGACGGCCATCC
GTCGCTCACCCGGATCGAGATGCCCGACGACTGGGTCGGGCATCCACAGCGCAAGGACTACCCGCTGGGCGGCATCCCCG
TCGAGTACCACGGCGCCCGGATACCACCGCCCGACGAGCGGAGGGCCTACAACTGA

Upstream 100 bases:

>100_bases
AGCAGATGCCGCTGGGGGTCAACCGCGACGAGGCCATCCGGGAAGCCGAACAGGCGGCGTTGGCGGTGCCGTCCACGATC
GAACTGAAGGGTCTGTTGCG

Downstream 100 bases:

>100_bases
TGACCACTCCCCCCGGCCCGCCCAACGCGGGCGGTGACGCGCGCACCGGCACCGACACGGTGATCGTCGTCGGCGGTGAG
GACTGGGAGCAGGTCGTCGC

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MTEANGTTGGGAGDPEVIDVRRGMFGAKGSGDTSGYGRLIRSVALPGGSPRPYGGHFDEVVDALAAALGQDLYDASVERI
VVYRDELTLEIARARLPVVAKTLRDDAALRFELCLGVSGVHYPGDAGRELHAAYPLMSITHNRRIRLEVAAPDDDPHIPS
LFSVYPTTDWHERETYDFFGIIFDGHPSLTRIEMPDDWVGHPQRKDYPLGGIPVEYHGARIPPPDERRAYN

Sequences:

>Translated_231_residues
MTEANGTTGGGAGDPEVIDVRRGMFGAKGSGDTSGYGRLIRSVALPGGSPRPYGGHFDEVVDALAAALGQDLYDASVERI
VVYRDELTLEIARARLPVVAKTLRDDAALRFELCLGVSGVHYPGDAGRELHAAYPLMSITHNRRIRLEVAAPDDDPHIPS
LFSVYPTTDWHERETYDFFGIIFDGHPSLTRIEMPDDWVGHPQRKDYPLGGIPVEYHGARIPPPDERRAYN
>Mature_230_residues
TEANGTTGGGAGDPEVIDVRRGMFGAKGSGDTSGYGRLIRSVALPGGSPRPYGGHFDEVVDALAAALGQDLYDASVERIV
VYRDELTLEIARARLPVVAKTLRDDAALRFELCLGVSGVHYPGDAGRELHAAYPLMSITHNRRIRLEVAAPDDDPHIPSL
FSVYPTTDWHERETYDFFGIIFDGHPSLTRIEMPDDWVGHPQRKDYPLGGIPVEYHGARIPPPDERRAYN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=201, Percent_Identity=32.3383084577114, Blast_Score=78, Evalue=7e-15,
Organism=Escherichia coli, GI145693162, Length=161, Percent_Identity=37.888198757764, Blast_Score=100, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI71990788, Length=146, Percent_Identity=34.9315068493151, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32563621, Length=146, Percent_Identity=34.9315068493151, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24656494, Length=127, Percent_Identity=34.6456692913386, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_MYCSJ (A3PWR9)

Other databases:

- EMBL:   CP000580
- RefSeq:   YP_001069837.1
- ProteinModelPortal:   A3PWR9
- SMR:   A3PWR9
- STRING:   A3PWR9
- EnsemblBacteria:   EBMYCT00000050563
- GeneID:   4877280
- GenomeReviews:   CP000580_GR
- KEGG:   mjl:Mjls_1548
- eggNOG:   COG0852
- GeneTree:   EBGT00050000017747
- HOGENOM:   HBG727675
- OMA:   VYPTNDW
- ProtClustDB:   PRK07785
- BioCyc:   MSP164757:MJLS_1548-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 25351; Mature: 25219

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEANGTTGGGAGDPEVIDVRRGMFGAKGSGDTSGYGRLIRSVALPGGSPRPYGGHFDEV
CCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHH
VDALAAALGQDLYDASVERIVVYRDELTLEIARARLPVVAKTLRDDAALRFELCLGVSGV
HHHHHHHHCCHHHHHCCEEEEEEECCHHEEHHHHHHHHHHHHHHCCHHEEEEEEECCCCC
HYPGDAGRELHAAYPLMSITHNRRIRLEVAAPDDDPHIPSLFSVYPTTDWHERETYDFFG
CCCCCCCCCHHHHCCCEEECCCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCEEEEE
IIFDGHPSLTRIEMPDDWVGHPQRKDYPLGGIPVEYHGARIPPPDERRAYN
EEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEANGTTGGGAGDPEVIDVRRGMFGAKGSGDTSGYGRLIRSVALPGGSPRPYGGHFDEV
CCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHH
VDALAAALGQDLYDASVERIVVYRDELTLEIARARLPVVAKTLRDDAALRFELCLGVSGV
HHHHHHHHCCHHHHHCCEEEEEEECCHHEEHHHHHHHHHHHHHHCCHHEEEEEEECCCCC
HYPGDAGRELHAAYPLMSITHNRRIRLEVAAPDDDPHIPSLFSVYPTTDWHERETYDFFG
CCCCCCCCCHHHHCCCEEECCCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCEEEEE
IIFDGHPSLTRIEMPDDWVGHPQRKDYPLGGIPVEYHGARIPPPDERRAYN
EEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA