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The map label for this gene is nuoE [H]

Identifier: 119867646

GI number: 119867646

Start: 1718897

End: 1719781

Strand: Reverse

Name: nuoE [H]

Synonym: Mkms_1600

Alternate gene names: 119867646

Gene position: 1719781-1718897 (Counterclockwise)

Preceding gene: 119867647

Following gene: 119867645

Centisome position: 29.98

GC content: 72.54

Gene sequence:

>885_bases
TTGCGCGAAGAAGAGACGGCCGTGAGCGTCTTCCTGGAACTCGGCCAGCGGCCGGACGAACCGGGACCGCCGGTCGGCGG
CCCCACCGCCTACCCCGCCGACGTCGCCGCCCGCCTGATCGCCGACGCCGCCCGCATCGTCACGCGCTACCCGCAGGCCC
GGTCGGCGCTGCTGCCGCTGCTGCACCTGGTGCAGGCCGAGGACGGCTGCCTCACCTCCGCCGGAATCGCGTTCTGCGCC
AACCAACTCGGGTTGACCGACGCCGAGGTGACGGCGGTGGCCACGTTCTACTCGATGTACCGGCGCACGCCGACCGGCGA
TTACCTGGTCGGGGTCTGCACCAACACCCTGTGCGCGATCATGGGCGGCGACGAGATCCTCGACGCGCTGCAGGACCATC
TCGGCGTAGCCGCCGGGCAGACCACCGACCCCGCCGAGGGACTGGCCGCGGTCACCCTCGAGCACATCGAGTGCAACGCC
GCGTGCGACTACGCACCCGTGGTGATGGTGAACTGGGAGTTCTTCGACAACCAGACGCCCGCCTCGGCCCGCGACCTCGT
CGATTCTCTGCGTGCGGGGACGCCCGCCGCGCCCACCCGCGGCGCACCGCTGTGCACGTTCCGCGAGACCGCGCGCACAC
TCGCCGGACTCGCCGATCCGCGTGCGGCCACCAACCCCGGGGGCACGGGTGAGGCGACGCTGGCCGGTCTGCGGGTGGCG
CGTGCGAACGGGATGGCGGCCCCGGATCCGGCCGAGACCGAAGGAGAAGGCACACAACCGGATCCGGAGATCGTCGAGGC
GGCCGACTCGACCAGGGACGAACCCGCCCCCGGACCCTCGGCCGCGGTACCGCGTCCCGGCGACGATTCGGAGCCGGGGT
CATGA

Upstream 100 bases:

>100_bases
GCGGTGGCGGCGATGTGCGAGGGCGGGATGGTCGCCGACGCCATCTCGGCGGTCGCGTCGATCGACCCGGTCATGGGCGG
GGTGGATAGGTGATGAGCGC

Downstream 100 bases:

>100_bases
CGGCGCTCACCCCGGTGCTGAGCCGGTTCTGGGACGAACCCGAATCGTGGACGCTGGAGACCTATCGGCGCCACGGCGGA
TACCGGGCGCTCGAACAGGC

Product: NADH dehydrogenase subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MREEETAVSVFLELGQRPDEPGPPVGGPTAYPADVAARLIADAARIVTRYPQARSALLPLLHLVQAEDGCLTSAGIAFCA
NQLGLTDAEVTAVATFYSMYRRTPTGDYLVGVCTNTLCAIMGGDEILDALQDHLGVAAGQTTDPAEGLAAVTLEHIECNA
ACDYAPVVMVNWEFFDNQTPASARDLVDSLRAGTPAAPTRGAPLCTFRETARTLAGLADPRAATNPGGTGEATLAGLRVA
RANGMAAPDPAETEGEGTQPDPEIVEAADSTRDEPAPGPSAAVPRPGDDSEPGS

Sequences:

>Translated_294_residues
MREEETAVSVFLELGQRPDEPGPPVGGPTAYPADVAARLIADAARIVTRYPQARSALLPLLHLVQAEDGCLTSAGIAFCA
NQLGLTDAEVTAVATFYSMYRRTPTGDYLVGVCTNTLCAIMGGDEILDALQDHLGVAAGQTTDPAEGLAAVTLEHIECNA
ACDYAPVVMVNWEFFDNQTPASARDLVDSLRAGTPAAPTRGAPLCTFRETARTLAGLADPRAATNPGGTGEATLAGLRVA
RANGMAAPDPAETEGEGTQPDPEIVEAADSTRDEPAPGPSAAVPRPGDDSEPGS
>Mature_294_residues
MREEETAVSVFLELGQRPDEPGPPVGGPTAYPADVAARLIADAARIVTRYPQARSALLPLLHLVQAEDGCLTSAGIAFCA
NQLGLTDAEVTAVATFYSMYRRTPTGDYLVGVCTNTLCAIMGGDEILDALQDHLGVAAGQTTDPAEGLAAVTLEHIECNA
ACDYAPVVMVNWEFFDNQTPASARDLVDSLRAGTPAAPTRGAPLCTFRETARTLAGLADPRAATNPGGTGEATLAGLRVA
RANGMAAPDPAETEGEGTQPDPEIVEAADSTRDEPAPGPSAAVPRPGDDSEPGS

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton transloca

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=196, Percent_Identity=35.7142857142857, Blast_Score=108, Evalue=5e-24,
Organism=Escherichia coli, GI1788621, Length=145, Percent_Identity=29.6551724137931, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17561328, Length=162, Percent_Identity=36.4197530864198, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI18859877, Length=178, Percent_Identity=34.2696629213483, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21355353, Length=160, Percent_Identity=35, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 30340; Mature: 30340

Theoretical pI: Translated: 4.01; Mature: 4.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREEETAVSVFLELGQRPDEPGPPVGGPTAYPADVAARLIADAARIVTRYPQARSALLPL
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LHLVQAEDGCLTSAGIAFCANQLGLTDAEVTAVATFYSMYRRTPTGDYLVGVCTNTLCAI
HHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHH
MGGDEILDALQDHLGVAAGQTTDPAEGLAAVTLEHIECNAACDYAPVVMVNWEFFDNQTP
HCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCC
ASARDLVDSLRAGTPAAPTRGAPLCTFRETARTLAGLADPRAATNPGGTGEATLAGLRVA
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
RANGMAAPDPAETEGEGTQPDPEIVEAADSTRDEPAPGPSAAVPRPGDDSEPGS
HCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MREEETAVSVFLELGQRPDEPGPPVGGPTAYPADVAARLIADAARIVTRYPQARSALLPL
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LHLVQAEDGCLTSAGIAFCANQLGLTDAEVTAVATFYSMYRRTPTGDYLVGVCTNTLCAI
HHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHH
MGGDEILDALQDHLGVAAGQTTDPAEGLAAVTLEHIECNAACDYAPVVMVNWEFFDNQTP
HCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCC
ASARDLVDSLRAGTPAAPTRGAPLCTFRETARTLAGLADPRAATNPGGTGEATLAGLRVA
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
RANGMAAPDPAETEGEGTQPDPEIVEAADSTRDEPAPGPSAAVPRPGDDSEPGS
HCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]