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The map label for this gene is nuoG [H]

Identifier: 119867644

GI number: 119867644

Start: 1715073

End: 1717478

Strand: Reverse

Name: nuoG [H]

Synonym: Mkms_1598

Alternate gene names: 119867644

Gene position: 1717478-1715073 (Counterclockwise)

Preceding gene: 119867645

Following gene: 119867643

Centisome position: 29.94

GC content: 71.57

Gene sequence:

>2406_bases
ATGACGCAGACCGCTGACACCGGGACCTCGAACGCACCTGCGGTCGAGATGGTCGAGCTCACGATCGACGGCGCCACCGT
CAGCGTGCCCAAGGGCACCCTGGTGATCCGGGCCGCCGAGCTGATCGGCATCCAGATCCCCCGGTTCTGCGACCACCCGC
TGCTCGACCCGGTGGGCGCCTGTCGCCAGTGCCTCGTCGAGGTGGAGGGCCAGCGCAAGCCGATGGCGTCGTGCACCACC
ACCGTCAGCCAGGACATGGTGGTGCACACCCAGTTCAGCTCCGAGGCCGCCGACAAGGCCCAGCGCGGTGTGATGGAACT
GCTGCTGATCAACCATCCCCTCGACTGCCCGGTCTGCGACAAGGGCGGCGAATGCCCGCTGCAGAACCAGGCGATGTCCA
ACGGCCGCGCCGAAACCCGCTTCACCGACGTCAAACGCACGTTCCCGAAACCGATCAACATCAGCTCCCAGGTGCTGCTC
GACCGCGAACGCTGCGTGCTGTGCGCGCGGTGCACCCGGTTCTCCCAGCAGATCGCCGGGGACCCGTTCATCGAACTTCT
CGAACGCGGTGCGCTGCAACAGGTCGGCATCGCCCCCGGCGAACCGTTCCAGTCCTACTTCTCGGGCAACACTGTGCAGA
TCTGTCCGGTCGGCGCGCTGACCGGGACCGCATACCGTTTCCGCGCAAGGCCTTTCGACCTGGTTTCCACGCCCAGCGTG
TGCGAACACTGCGCCTCGGGGTGCGCACAGCGCACCGACCACCGCCGCGGAAAGGTGCTGCGCCGCCTGGCCGGTGACGA
TCCGCAGGTCAACGAGGAGTGGAACTGCGACAAGGGTCGCTGGGCGTTCACGTACACGGATGTCGGTGACCGCATCGCCA
CACCGCTGGTCCGTGACGCCGACGGGGTGTTGCAGCCGGCGTCGTGGTCGGAGGCGCTCGCCGTCGCCGCCGCCGGACTC
GCCGTGGCGAACGCACGGGCCGGTGTGGTGGTCGGTGGCCGGGCCACCGTCGAAGATGCCTATGCCTACGCGAAGTTCGC
CCGAATGGTGTTGGGCACCAACGACGTCGACTTCCGGGTGCGACCACACAGCGCCGAGGAGGCCGACTTCCTCACCGCGC
ACGTGGCGGGCCGGCCGATGCAGGTCACCTACGCCGACCTGGAGAACGCCCCCGCGGTCCTGCTCGCCGGATTCGAACCC
GAGGACGAATCACCGATCGTGTTCCTGCGGCTGCGCAAAGCCGTACGCAAACAGGGACTGCAGGTGCTCTCGGTCGCACC
GTTCGCCGGCCGGGGGCTGACCAAACTCTCCGGCCGCCTCGTCACCGCCGCACCGGGTGGGGAGGCCGCCGCACTCGACG
CGCTGACCGACGAGCCTCTGCTGCGCCTGCCCGGTGTCGTCATCCTCGTCGGGGAACGCCTGGCCACCGCACCCGGGGCG
CTGACCGCGGCGGCCCGGCTGGCGGCCGCCACCGGTGCGCGGCTGGCGTGGATCCCCCGCCGAGCCGGTGAGCGCGGCGC
CGTGGAGGCCGGGGCGCTGCCCACCCTGCTGCCGGGCGGACGTCCCGTCACCGACGACTCCGCCCGCGCCCAGGTGGCGG
CCGCGTGGCATACCGACGCGCTCCCGGACGGTCCGGGCCGCGACACCGGCGAGATACTCGACGCCGCGCGCTCCGGGGCG
CTGAGCGCACTGGTGTGCGGCGGCGTCGACGTCACCGATCTGCCGGATCCGCACGCCGCACTCGCCGCGTTGGCGGCCGT
ACCGTTCGTGGTGAGTCTCGAGCTGCGCGAAAGCGAGGTCACCCGCGCCGCCGACGTGGTGTTCCCGGTGGCTCCGGTGG
CCGAGAAGGGCGGTGCGTTCCTCGACTGGGAGGGCAGGCTGCGCTCGTTCGGACCGGCCCTGCCCAGCAACGCCATCCCG
GATCTGCGGGTGCTGAACTTCCTCGCCGACGAGATGGGTGTCGACCTCGGTCTGCCGGATGCGCAGACCGCCGGTGCGGA
ACTCGGCCGGCTGGGCTGGTGGGACGGTCCGCGTCCGCACTGCGCCCACGAGGCGCCGGCACCGCCGCATGTCGGACCCG
GCCAGGCGGTGCTGACGGGCTGGCGCATGCTGCTCGACCTCGGGCGGATGCAGGACGGTGAGCCCCATCTGGCCGGCACC
GCACCGCCGGCCGTCGTCCGGCTGTCCGGTCCCACCGCCGACGCCATCGGCGCGGCGCCCGGCGAGTTGGTCACCGTCGG
CACCGAACGCGGTCAGGTCACGCTGCCGCTCACCGTCACCGACATGCCCGACGGCGTGGTCTGGTTACCGCTGAGCTCCC
GCGGCTCGCAGGTGCACCGCCAACTCGGTGTGAGCACCGGCGCCATCGTGTCGATCGCCGCGTCGGGCGGGCGGACGGCG
CCGTGA

Upstream 100 bases:

>100_bases
CGTACGCCACCGCGCTCGCCGAATGTGCGGTTCCATCCGCGACACACCGCCCTATGCGTACGAAACCGCACACTCGCGGC
GGACGAAAGTGGGGGGTGCG

Downstream 100 bases:

>100_bases
TCCACCCCGACCCCACGCTGTTCGGCCACGACCCGTGGTGGCTCATCCTGGCCAAGGCCGTCGGCGTCTTCGTGTTCCTG
GTGCTCACGGTGCTCGCCGC

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 801; Mature: 800

Protein sequence:

>801_residues
MTQTADTGTSNAPAVEMVELTIDGATVSVPKGTLVIRAAELIGIQIPRFCDHPLLDPVGACRQCLVEVEGQRKPMASCTT
TVSQDMVVHTQFSSEAADKAQRGVMELLLINHPLDCPVCDKGGECPLQNQAMSNGRAETRFTDVKRTFPKPINISSQVLL
DRERCVLCARCTRFSQQIAGDPFIELLERGALQQVGIAPGEPFQSYFSGNTVQICPVGALTGTAYRFRARPFDLVSTPSV
CEHCASGCAQRTDHRRGKVLRRLAGDDPQVNEEWNCDKGRWAFTYTDVGDRIATPLVRDADGVLQPASWSEALAVAAAGL
AVANARAGVVVGGRATVEDAYAYAKFARMVLGTNDVDFRVRPHSAEEADFLTAHVAGRPMQVTYADLENAPAVLLAGFEP
EDESPIVFLRLRKAVRKQGLQVLSVAPFAGRGLTKLSGRLVTAAPGGEAAALDALTDEPLLRLPGVVILVGERLATAPGA
LTAAARLAAATGARLAWIPRRAGERGAVEAGALPTLLPGGRPVTDDSARAQVAAAWHTDALPDGPGRDTGEILDAARSGA
LSALVCGGVDVTDLPDPHAALAALAAVPFVVSLELRESEVTRAADVVFPVAPVAEKGGAFLDWEGRLRSFGPALPSNAIP
DLRVLNFLADEMGVDLGLPDAQTAGAELGRLGWWDGPRPHCAHEAPAPPHVGPGQAVLTGWRMLLDLGRMQDGEPHLAGT
APPAVVRLSGPTADAIGAAPGELVTVGTERGQVTLPLTVTDMPDGVVWLPLSSRGSQVHRQLGVSTGAIVSIAASGGRTA
P

Sequences:

>Translated_801_residues
MTQTADTGTSNAPAVEMVELTIDGATVSVPKGTLVIRAAELIGIQIPRFCDHPLLDPVGACRQCLVEVEGQRKPMASCTT
TVSQDMVVHTQFSSEAADKAQRGVMELLLINHPLDCPVCDKGGECPLQNQAMSNGRAETRFTDVKRTFPKPINISSQVLL
DRERCVLCARCTRFSQQIAGDPFIELLERGALQQVGIAPGEPFQSYFSGNTVQICPVGALTGTAYRFRARPFDLVSTPSV
CEHCASGCAQRTDHRRGKVLRRLAGDDPQVNEEWNCDKGRWAFTYTDVGDRIATPLVRDADGVLQPASWSEALAVAAAGL
AVANARAGVVVGGRATVEDAYAYAKFARMVLGTNDVDFRVRPHSAEEADFLTAHVAGRPMQVTYADLENAPAVLLAGFEP
EDESPIVFLRLRKAVRKQGLQVLSVAPFAGRGLTKLSGRLVTAAPGGEAAALDALTDEPLLRLPGVVILVGERLATAPGA
LTAAARLAAATGARLAWIPRRAGERGAVEAGALPTLLPGGRPVTDDSARAQVAAAWHTDALPDGPGRDTGEILDAARSGA
LSALVCGGVDVTDLPDPHAALAALAAVPFVVSLELRESEVTRAADVVFPVAPVAEKGGAFLDWEGRLRSFGPALPSNAIP
DLRVLNFLADEMGVDLGLPDAQTAGAELGRLGWWDGPRPHCAHEAPAPPHVGPGQAVLTGWRMLLDLGRMQDGEPHLAGT
APPAVVRLSGPTADAIGAAPGELVTVGTERGQVTLPLTVTDMPDGVVWLPLSSRGSQVHRQLGVSTGAIVSIAASGGRTA
P
>Mature_800_residues
TQTADTGTSNAPAVEMVELTIDGATVSVPKGTLVIRAAELIGIQIPRFCDHPLLDPVGACRQCLVEVEGQRKPMASCTTT
VSQDMVVHTQFSSEAADKAQRGVMELLLINHPLDCPVCDKGGECPLQNQAMSNGRAETRFTDVKRTFPKPINISSQVLLD
RERCVLCARCTRFSQQIAGDPFIELLERGALQQVGIAPGEPFQSYFSGNTVQICPVGALTGTAYRFRARPFDLVSTPSVC
EHCASGCAQRTDHRRGKVLRRLAGDDPQVNEEWNCDKGRWAFTYTDVGDRIATPLVRDADGVLQPASWSEALAVAAAGLA
VANARAGVVVGGRATVEDAYAYAKFARMVLGTNDVDFRVRPHSAEEADFLTAHVAGRPMQVTYADLENAPAVLLAGFEPE
DESPIVFLRLRKAVRKQGLQVLSVAPFAGRGLTKLSGRLVTAAPGGEAAALDALTDEPLLRLPGVVILVGERLATAPGAL
TAAARLAAATGARLAWIPRRAGERGAVEAGALPTLLPGGRPVTDDSARAQVAAAWHTDALPDGPGRDTGEILDAARSGAL
SALVCGGVDVTDLPDPHAALAALAAVPFVVSLELRESEVTRAADVVFPVAPVAEKGGAFLDWEGRLRSFGPALPSNAIPD
LRVLNFLADEMGVDLGLPDAQTAGAELGRLGWWDGPRPHCAHEAPAPPHVGPGQAVLTGWRMLLDLGRMQDGEPHLAGTA
PPAVVRLSGPTADAIGAAPGELVTVGTERGQVTLPLTVTDMPDGVVWLPLSSRGSQVHRQLGVSTGAIVSIAASGGRTAP

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton transloca

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=415, Percent_Identity=37.3493975903614, Blast_Score=252, Evalue=8e-67,
Organism=Escherichia coli, GI145693161, Length=411, Percent_Identity=29.683698296837, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI3868721, Length=200, Percent_Identity=29.5, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32566231, Length=516, Percent_Identity=36.6279069767442, Blast_Score=264, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17565758, Length=516, Percent_Identity=36.6279069767442, Blast_Score=264, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI193209088, Length=259, Percent_Identity=44.015444015444, Blast_Score=196, Evalue=5e-50,
Organism=Drosophila melanogaster, GI24640559, Length=422, Percent_Identity=39.0995260663507, Blast_Score=257, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24640557, Length=422, Percent_Identity=39.0995260663507, Blast_Score=257, Evalue=2e-68,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574 [H]

Pfam domain/function: PF00111 Fer2; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 84047; Mature: 83915

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTADTGTSNAPAVEMVELTIDGATVSVPKGTLVIRAAELIGIQIPRFCDHPLLDPVGA
CCCCCCCCCCCCCCEEEEEEEECCEEEECCCCEEEEEEEHHHCEECCHHCCCCCCCHHHH
CRQCLVEVEGQRKPMASCTTTVSQDMVVHTQFSSEAADKAQRGVMELLLINHPLDCPVCD
HHHHHHHHCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCC
KGGECPLQNQAMSNGRAETRFTDVKRTFPKPINISSQVLLDRERCVLCARCTRFSQQIAG
CCCCCCCCHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHEECHHHHHHHHHHHHHHHHHCC
DPFIELLERGALQQVGIAPGEPFQSYFSGNTVQICPVGALTGTAYRFRARPFDLVSTPSV
CHHHHHHHCCCHHHCCCCCCCCHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCCCHHH
CEHCASGCAQRTDHRRGKVLRRLAGDDPQVNEEWNCDKGRWAFTYTDVGDRIATPLVRDA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHCCHHHCC
DGVLQPASWSEALAVAAAGLAVANARAGVVVGGRATVEDAYAYAKFARMVLGTNDVDFRV
CCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEE
RPHSAEEADFLTAHVAGRPMQVTYADLENAPAVLLAGFEPEDESPIVFLRLRKAVRKQGL
CCCCCCCCCEEEEECCCCCEEEEEECCCCCCEEEEECCCCCCCCCEEEHHHHHHHHHCCC
QVLSVAPFAGRGLTKLSGRLVTAAPGGEAAALDALTDEPLLRLPGVVILVGERLATAPGA
EEEEECCCCCCCCHHHCCEEEEECCCCCCCEECCCCCCCHHHCCCEEEEECCHHCCCCCH
LTAAARLAAATGARLAWIPRRAGERGAVEAGALPTLLPGGRPVTDDSARAQVAAAWHTDA
HHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
LPDGPGRDTGEILDAARSGALSALVCGGVDVTDLPDPHAALAALAAVPFVVSLELRESEV
CCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCEEEEEEECHHHH
TRAADVVFPVAPVAEKGGAFLDWEGRLRSFGPALPSNAIPDLRVLNFLADEMGVDLGLPD
HHHHHHHCCCCCHHHCCCEEEEECCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
AQTAGAELGRLGWWDGPRPHCAHEAPAPPHVGPGQAVLTGWRMLLDLGRMQDGEPHLAGT
CHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
APPAVVRLSGPTADAIGAAPGELVTVGTERGQVTLPLTVTDMPDGVVWLPLSSRGSQVHR
CCCEEEEECCCCCHHCCCCCCCEEEEECCCCEEEEEEEEECCCCCEEEEEECCCCHHHHH
QLGVSTGAIVSIAASGGRTAP
HHCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
TQTADTGTSNAPAVEMVELTIDGATVSVPKGTLVIRAAELIGIQIPRFCDHPLLDPVGA
CCCCCCCCCCCCCEEEEEEEECCEEEECCCCEEEEEEEHHHCEECCHHCCCCCCCHHHH
CRQCLVEVEGQRKPMASCTTTVSQDMVVHTQFSSEAADKAQRGVMELLLINHPLDCPVCD
HHHHHHHHCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCC
KGGECPLQNQAMSNGRAETRFTDVKRTFPKPINISSQVLLDRERCVLCARCTRFSQQIAG
CCCCCCCCHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHEECHHHHHHHHHHHHHHHHHCC
DPFIELLERGALQQVGIAPGEPFQSYFSGNTVQICPVGALTGTAYRFRARPFDLVSTPSV
CHHHHHHHCCCHHHCCCCCCCCHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCCCHHH
CEHCASGCAQRTDHRRGKVLRRLAGDDPQVNEEWNCDKGRWAFTYTDVGDRIATPLVRDA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHCCHHHCC
DGVLQPASWSEALAVAAAGLAVANARAGVVVGGRATVEDAYAYAKFARMVLGTNDVDFRV
CCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEE
RPHSAEEADFLTAHVAGRPMQVTYADLENAPAVLLAGFEPEDESPIVFLRLRKAVRKQGL
CCCCCCCCCEEEEECCCCCEEEEEECCCCCCEEEEECCCCCCCCCEEEHHHHHHHHHCCC
QVLSVAPFAGRGLTKLSGRLVTAAPGGEAAALDALTDEPLLRLPGVVILVGERLATAPGA
EEEEECCCCCCCCHHHCCEEEEECCCCCCCEECCCCCCCHHHCCCEEEEECCHHCCCCCH
LTAAARLAAATGARLAWIPRRAGERGAVEAGALPTLLPGGRPVTDDSARAQVAAAWHTDA
HHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
LPDGPGRDTGEILDAARSGALSALVCGGVDVTDLPDPHAALAALAAVPFVVSLELRESEV
CCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCEEEEEEECHHHH
TRAADVVFPVAPVAEKGGAFLDWEGRLRSFGPALPSNAIPDLRVLNFLADEMGVDLGLPD
HHHHHHHCCCCCHHHCCCEEEEECCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
AQTAGAELGRLGWWDGPRPHCAHEAPAPPHVGPGQAVLTGWRMLLDLGRMQDGEPHLAGT
CHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
APPAVVRLSGPTADAIGAAPGELVTVGTERGQVTLPLTVTDMPDGVVWLPLSSRGSQVHR
CCCEEEEECCCCCHHCCCCCCCEEEEECCCCEEEEEEEEECCCCCEEEEEECCCCHHHHH
QLGVSTGAIVSIAASGGRTAP
HHCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]