BacMap

Definition	Mycobacterium sp. KMS chromosome, complete genome.
Accession	NC_008705
Length	5,737,227

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The map label for this gene is fadB1 [H]

Identifier: 119867633

GI number: 119867633

Start: 1702659

End: 1703432

Strand: Reverse

Name: fadB1 [H]

Synonym: Mkms_1587

Alternate gene names: 119867633

Gene position: 1703432-1702659 (Counterclockwise)

Preceding gene: 119867634

Following gene: 119867630

Centisome position: 29.69

GC content: 70.93

Gene sequence:

>774_bases
ATGACCTCCCTCGTCCAGGTGGCCGACGTCGACCACGTCCGCCTGCTCACCATGAACCGGCCCGAGGCGCGAAATGCGCT
CAGCCGCGACCTCATTCGGGCGCTGTACGCGTCGCTGTCCGAGGCCGACGACGACGCGTCGGTGCACGTCGTGGTGCTCA
CCGGCGCAGACCCCGCGTTCTGCGCAGGGGTGGACCTCAAGGAGGCCGCCCGCGAGGGCACGGAGTACTTCGCCGAGTTC
CAATCGCAGAGCTGCATCACCCGGGTCGCCGAGATGCGGACACCGGTCATCGGGGCGGTCAACGGGGCGGTGTTCACCGG
CGGGCTGGAGATGGCGCTGGGCTGCGACTTCCTCATCGCATCGCACCGTGCGGTGTTCGCCGACACCCACGCCCGCGTCG
GCATCCTGCCCGGCGGCGGGATGACGGCGCGGCTGCCACAGGTGGTCGGTGCCGCGATGGCGCGACGGCTGTCGATGACC
GGTGAGGTCGTCGATGCCGAGCGGGCCGAGCGGATCGGGCTGGTGACCGAGGTGGTGCCGCACGAGCGGCTGCTCGATCG
CGCCATCGAATTGGCCGCCCAGATCGCCGAGGTGCCCGCGGCGACCATGGCCGGACTCAAGGAGATCTACACGCGCGGCG
CCGACGCCGTCATCTCCCCCGCCCTGGCCGCAGAGCAGGACATCGCGGGATCGCAGGCCCGCGACTTCGCCGGCCTGTCT
ACCCGGTTCGACGACGTGACCGCCCGCAATCGCGCTCAGATCGCGACCGACTGA

Upstream 100 bases:

>100_bases
CACGGTGACCGCCGCGGTGACGCTCGCCCTCGGGGCGCTGCCGCAGCCACTGCTCGACCTCGCGAACAACGCCGACCTGT
TCCTGCGTTAGCTTGCGTAT

Downstream 100 bases:

>100_bases
CGCCGACCCAGCCCGATTGTGCGGTTTCATCCGCGACACGCCACATGTGGCGGATCAATCCGCACACTCGGCGGCTGACG
CTACACCGCTTGGGCGAACC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MTSLVQVADVDHVRLLTMNRPEARNALSRDLIRALYASLSEADDDASVHVVVLTGADPAFCAGVDLKEAAREGTEYFAEF
QSQSCITRVAEMRTPVIGAVNGAVFTGGLEMALGCDFLIASHRAVFADTHARVGILPGGGMTARLPQVVGAAMARRLSMT
GEVVDAERAERIGLVTEVVPHERLLDRAIELAAQIAEVPAATMAGLKEIYTRGADAVISPALAAEQDIAGSQARDFAGLS
TRFDDVTARNRAQIATD

Sequences:

>Translated_257_residues
MTSLVQVADVDHVRLLTMNRPEARNALSRDLIRALYASLSEADDDASVHVVVLTGADPAFCAGVDLKEAAREGTEYFAEF
QSQSCITRVAEMRTPVIGAVNGAVFTGGLEMALGCDFLIASHRAVFADTHARVGILPGGGMTARLPQVVGAAMARRLSMT
GEVVDAERAERIGLVTEVVPHERLLDRAIELAAQIAEVPAATMAGLKEIYTRGADAVISPALAAEQDIAGSQARDFAGLS
TRFDDVTARNRAQIATD
>Mature_256_residues
TSLVQVADVDHVRLLTMNRPEARNALSRDLIRALYASLSEADDDASVHVVVLTGADPAFCAGVDLKEAAREGTEYFAEFQ
SQSCITRVAEMRTPVIGAVNGAVFTGGLEMALGCDFLIASHRAVFADTHARVGILPGGGMTARLPQVVGAAMARRLSMTG
EVVDAERAERIGLVTEVVPHERLLDRAIELAAQIAEVPAATMAGLKEIYTRGADAVISPALAAEQDIAGSQARDFAGLST
RFDDVTARNRAQIATD

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=200, Percent_Identity=37.5, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI4502327, Length=185, Percent_Identity=32.972972972973, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI31542718, Length=197, Percent_Identity=29.9492385786802, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI20127408, Length=203, Percent_Identity=29.5566502463054, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI157694516, Length=230, Percent_Identity=27.3913043478261, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI213417737, Length=230, Percent_Identity=27.3913043478261, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI70995211, Length=242, Percent_Identity=28.9256198347107, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI68989263, Length=185, Percent_Identity=29.7297297297297, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI37594469, Length=176, Percent_Identity=26.7045454545455, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI37594471, Length=176, Percent_Identity=26.7045454545455, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI62530384, Length=180, Percent_Identity=28.3333333333333, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI157694520, Length=210, Percent_Identity=26.6666666666667, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI295842266, Length=178, Percent_Identity=28.0898876404494, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI221136756, Length=175, Percent_Identity=28, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI221136753, Length=175, Percent_Identity=28, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI221307494, Length=175, Percent_Identity=26.8571428571429, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787659, Length=228, Percent_Identity=33.7719298245614, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI221142681, Length=198, Percent_Identity=38.3838383838384, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1788682, Length=192, Percent_Identity=31.7708333333333, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787660, Length=237, Percent_Identity=32.0675105485232, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788597, Length=180, Percent_Identity=31.6666666666667, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790281, Length=184, Percent_Identity=27.7173913043478, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082183, Length=207, Percent_Identity=26.5700483091787, Blast_Score=71, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI25145438, Length=203, Percent_Identity=37.9310344827586, Blast_Score=140, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17554946, Length=230, Percent_Identity=31.7391304347826, Blast_Score=125, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17540714, Length=219, Percent_Identity=31.9634703196347, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17536985, Length=217, Percent_Identity=26.2672811059908, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560910, Length=195, Percent_Identity=29.2307692307692, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17534483, Length=234, Percent_Identity=26.9230769230769, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25144276, Length=174, Percent_Identity=31.0344827586207, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17508951, Length=174, Percent_Identity=31.0344827586207, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17558304, Length=167, Percent_Identity=31.1377245508982, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17508953, Length=186, Percent_Identity=30.1075268817204, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17535521, Length=197, Percent_Identity=24.8730964467005, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17549921, Length=211, Percent_Identity=28.9099526066351, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17540306, Length=196, Percent_Identity=29.0816326530612, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25144157, Length=233, Percent_Identity=24.0343347639485, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25144160, Length=233, Percent_Identity=24.0343347639485, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6320241, Length=194, Percent_Identity=28.8659793814433, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI20129971, Length=187, Percent_Identity=37.9679144385027, Blast_Score=138, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24653477, Length=187, Percent_Identity=37.9679144385027, Blast_Score=138, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24653139, Length=190, Percent_Identity=35.7894736842105, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24650670, Length=222, Percent_Identity=31.0810810810811, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21357171, Length=193, Percent_Identity=31.0880829015544, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI19922422, Length=235, Percent_Identity=29.3617021276596, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28571730, Length=152, Percent_Identity=28.9473684210526, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571729, Length=152, Percent_Identity=28.9473684210526, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24654903, Length=245, Percent_Identity=24.8979591836735, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24583165, Length=197, Percent_Identity=24.3654822335025, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19921018, Length=241, Percent_Identity=24.4813278008299, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI19921000, Length=185, Percent_Identity=28.6486486486486, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27218; Mature: 27087

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLVQVADVDHVRLLTMNRPEARNALSRDLIRALYASLSEADDDASVHVVVLTGADPAF
CCCCHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHH
CAGVDLKEAAREGTEYFAEFQSQSCITRVAEMRTPVIGAVNGAVFTGGLEMALGCDFLIA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHH
SHRAVFADTHARVGILPGGGMTARLPQVVGAAMARRLSMTGEVVDAERAERIGLVTEVVP
CCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
HERLLDRAIELAAQIAEVPAATMAGLKEIYTRGADAVISPALAAEQDIAGSQARDFAGLS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHCCHHHHHHHCCCCHHHHHCCCC
TRFDDVTARNRAQIATD
CHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TSLVQVADVDHVRLLTMNRPEARNALSRDLIRALYASLSEADDDASVHVVVLTGADPAF
CCCHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHH
CAGVDLKEAAREGTEYFAEFQSQSCITRVAEMRTPVIGAVNGAVFTGGLEMALGCDFLIA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHH
SHRAVFADTHARVGILPGGGMTARLPQVVGAAMARRLSMTGEVVDAERAERIGLVTEVVP
CCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
HERLLDRAIELAAQIAEVPAATMAGLKEIYTRGADAVISPALAAEQDIAGSQARDFAGLS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHCCHHHHHHHCCCCHHHHHCCCC
TRFDDVTARNRAQIATD
CHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]